Tyan013695.1


Basic Information
Transcription Factor Domain
Sequence Information
Similar Transcription Factors

Basic Information

Insect
Topomyia yanbarensis
Gene Symbol
-
Assembly
GCA_030247195.1
Location
CM058068.1:201458252-201480698[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 49 0.0043 0.43 13.1 0.6 2 23 47 70 47 70 0.92
2 49 1.2e-05 0.0013 21.1 0.5 1 23 76 98 76 98 0.97
3 49 0.00014 0.014 17.8 1.9 1 23 104 126 104 126 0.98
4 49 2.7e-06 0.00028 23.2 0.8 1 23 132 154 132 154 0.99
5 49 0.00012 0.013 18.0 1.4 1 23 160 182 160 182 0.98
6 49 0.043 4.4 10.0 0.1 1 23 188 210 188 210 0.98
7 49 0.022 2.2 10.9 2.5 1 21 216 236 216 238 0.95
8 49 0.0049 0.5 12.9 6.5 1 21 244 264 244 266 0.95
9 49 6.6 6.7e+02 3.1 5.9 1 21 272 292 272 294 0.96
10 49 0.005 0.51 12.9 0.1 1 23 302 324 302 324 0.94
11 49 0.00063 0.065 15.7 1.3 2 23 343 364 342 364 0.98
12 49 0.0018 0.18 14.3 1.6 1 23 370 392 370 392 0.98
13 49 0.073 7.4 9.2 1.0 1 21 398 418 398 419 0.91
14 49 0.00035 0.036 16.5 2.1 1 23 426 448 426 448 0.99
15 49 0.0012 0.12 14.9 1.8 1 23 454 476 454 476 0.98
16 49 6.7e-05 0.0068 18.8 0.1 1 23 482 504 482 504 0.97
17 49 0.00055 0.056 15.9 0.6 3 23 512 532 510 532 0.94
18 49 3e-06 0.00031 23.0 0.6 1 23 538 560 538 560 0.98
19 49 2.3e-05 0.0023 20.3 4.0 1 23 566 588 566 588 0.98
20 49 2e-05 0.002 20.5 0.4 1 23 594 616 594 616 0.99
21 49 0.00033 0.034 16.6 0.3 1 23 624 646 624 646 0.97
22 49 0.05 5 9.8 1.1 1 23 652 675 652 675 0.95
23 49 9.9e-05 0.01 18.3 0.9 1 23 680 702 680 702 0.99
24 49 4.4e-06 0.00045 22.5 1.9 1 23 708 731 708 731 0.97
25 49 9e-05 0.0092 18.4 1.9 1 23 765 787 765 787 0.98
26 49 0.00027 0.027 16.9 6.0 1 23 793 815 793 815 0.98
27 49 1e-06 0.00011 24.5 2.1 1 23 821 843 821 843 0.99
28 49 4.7e-06 0.00048 22.4 1.0 1 23 849 871 849 871 0.98
29 49 0.018 1.9 11.1 0.1 3 23 879 899 877 899 0.96
30 49 0.0017 0.18 14.4 2.8 1 21 906 926 906 928 0.95
31 49 0.0047 0.47 13.0 6.6 1 21 934 954 934 956 0.96
32 49 1.6e-05 0.0017 20.7 0.2 1 23 962 984 962 984 0.99
33 49 0.0022 0.23 14.0 0.0 1 23 992 1014 992 1014 0.95
34 49 0.071 7.3 9.3 0.9 2 23 1021 1043 1021 1043 0.95
35 49 8e-07 8.2e-05 24.8 0.5 1 23 1048 1070 1048 1070 0.99
36 49 6.1e-06 0.00062 22.1 1.2 2 23 1077 1099 1076 1099 0.96
37 49 2.6e-05 0.0027 20.1 0.8 2 23 1134 1156 1133 1156 0.97
38 49 2.7e-06 0.00027 23.2 1.3 1 23 1156 1178 1156 1178 0.98
39 49 0.5 51 6.6 3.6 1 23 1184 1206 1184 1206 0.90
40 49 4.8e-05 0.0049 19.3 1.3 1 23 1212 1234 1212 1234 0.99
41 49 0.00019 0.019 17.4 3.5 1 23 1240 1262 1240 1262 0.97
42 49 0.035 3.5 10.3 0.8 1 23 1268 1290 1268 1290 0.95
43 49 0.0011 0.11 15.0 1.7 1 21 1297 1317 1297 1319 0.95
44 49 0.0087 0.89 12.1 7.5 1 23 1325 1347 1325 1347 0.97
45 49 0.016 1.6 11.3 0.6 1 21 1353 1373 1353 1375 0.95
46 49 0.00094 0.096 15.2 0.1 1 23 1383 1405 1383 1405 0.94
47 49 0.0018 0.18 14.3 1.2 1 23 1411 1434 1411 1434 0.96
48 49 0.00059 0.06 15.8 2.4 1 23 1439 1461 1439 1461 0.98
49 49 2.4e-06 0.00024 23.4 0.2 2 23 1468 1490 1467 1490 0.95

Sequence Information

Coding Sequence
atgcgtcctCCCCACGCACACCTAATGCCCCGTGGATTAATTCCCTGGTTGGTCAAACAAGCACCAAATAAGCATAGAAATTACTCTGCTCTGTCCAAAGCAATCTATTCCTATGATAATACCGGTCTCAAAAAGCCCAAATGCTACATTTGCGATCGACAATTTGCTGAACTGCGCTACCTAAAACTGCACATGCGATCAACAGCCCACGCCGAAAAAGTTTCCCATCCGTGCGACATTTGCGGGAAAATCATTGCGCGGAAGGACTCACTCGAAAGACACCGAAGAACGCATACCGGCGAACGACCCTTTTCTTGCGAAATATGTGGCAAAAGTTTCCCATGCAAACGCTCGCTGGTCAACCATATGCGATTGCATACTGGAAATCACAACTACAGGTGCGATGTTTGTGACAAAGGATACAGTTCAAGGAGTAAGCTCATGATCCACTTGAGGACCCATACAGGCGAGCGTCCGTACAAATGTGAGCTATGTGAAAAAAGTTTCGCTAGTCAGTTGTACCTGAGAAATCATACGCTAAGACATGAGGAAAATCACGAGTTCAGCTGTGGCGTTTGTGGCAAAGGATGTGGTACGGGAGCTCTACTTGCGATTCACGAGAAAACCCACAGCACCGAACGTCCATACAAATGTGACATTTGCGGCAAGGAATTTTTCGCTATTGGACAGTTCAATCGGCATCTGAAGTGTCATAATGACGAACGTCTGCATCGGTGTACTGTTTGCACTAAAGAATTCAAAAACAATCAGCACCTCGTCGTACACATGCGCTGTCACACTGGTGAACGGCCATACAAATGTGAAGTTTGCTGTTCTTCGTTCAGGTTTTCTAACAACCTGGTAGAGCACATGAAATGTCACTTAGACGTagcgtcaagaccattccaatgTGGCGTATGCGGAGCAAAATTTAGTCTGCAAAGAACGCTTACCGCACACAGTGTGGTTCATGGCCATTCCGACGACCAGCCGGATCGCGATGGTACCGGTCTCGAAAAGCCCACCAAATGCGACATTTGCGATCGACTAATCACTAAACTAGGAAACTTCAAAAGACACATGCGAACTCACACCGAGAATACAGCCCACCGGTGCGACATTTGCGGAAAAACCCTTAAGTGGAGGGACTCACTCGAAAGTCATAGAAGAATGCATACCGGCGAACGGCCGTTTCGTTGCGAAATATGTGGCAAAGGTTTCGCCTGTAAACGCACTCTGAACGGACATACGAAATTGAATGCTGGAAATCACGACTACAAGTGCGATGTTTGTGGCAAAGCATACAGTCCAAAGTGTAAGTTTGTGGACCACATGAAATCCCATGCAGGAGAGCGTCCGTACGAATGTGacatatgtggaaaaaaatttgcTAGCCAGTGCATCCTGAGAAATCATACGCTAAGACATACAGAAAATTATGAATTCAGCTGCGATGTTTGTGGCAAAGGATTTGCTACAAGAGGCAGCCTTGTGAATCACGGGAAATCGCATAGCACCGGGCGCCCACTCGCATGTGACATATGTGGCAAAACCTTCTACAATAACCAGACgctgcggtatcacagtgacaGGCATATGACGGAACATCCTTTCAAATGTAACATTTGTGGCAAGGGATTCTCTTTCCTTGGTCAGCTCAATAAGCATTGGAAGATTCATAATGCCCCACGTCTCCATCGGTGTAATGTTTGCAACAAAGAGTTCAGAACTAAGTTTCTGCTTGTCACACACATGCGGTCTCACACTGATGAACGGCCATACAAATGTGAAATTTGCGGTTCTTCGTTTAGGACTTCTACTACACTGGTTGGGCACATGAAAATTCACGCAAATCTAGCATCAAACCCGTTCGAATGTGACGTATGCGGAGCAAAGTTTAGCCAACAAAGAACTCTTAGCATTCACAGTAAAGTTCATCGGAAGACACCGTGCCATGAATGTCCTAATTGTAACAAACAATTTCTCGCCTCTAGAGACCTGAACAGGCACAGAGTTACCGTTCACAATGATCGACCGTACAAATGTACGATCTGTGACATAACGACCACTACCATGCAGAACTTGCGGTCACATTTGAAAGTTCACTATGGCGCGATTCGGCACAAATGTCACATTTGTGGGAAGAGTTACGCAAGGAAATCCGGTCTTAATGATCACGTCAAAGTAGTGCACGCTCAAGATAAACGCCTCCACTCCGACCACGAGCTGGATGGTGATGGTAGCGAACTAGAAAAACGGCACATGGGAACCACTAACCACGAAAAAGCTTCTCACCGGTGCGACATTTGTGGGAAAAGCTTTGAGAAACCATACGTCTACGTAAGACATAGAAGAATGCATACCGGCGAACGACCGTTTTCATGCGTAATATGTGGCAAATGTTTCACATGCCAATCCTATCTGCGCAATCATATGAGATTGCATACCGAAAATCACATCTACAAGTGCGATGTTTGCGGCAAAGGTTACAGTTCAAAGTCTAAGTTCACGACCCACATGAGATCCCATACAGGCGAGCGTCCGTACAAATGTGACATATGTGGAAAAAGTTTTGCTAGTCAGTTGTATCTGAGAAATCATACGCTAAGACATGAGGAAAATTACGAGTTCGGCTGTGATTTTTGTGGCAAAGGATTTGGTACAAGAGCTAAGCTTGCGGTTCACGAGGAAATCCACAGCACCACCGAGCGCCCATTCAAATGTAACATTTGCGACAAGGGATTTTCCTTTATTGGACAGCTCAATCAGCATCTGAAATGTCATAACGACGAACGTCTGTATCGGTGTAATGTTTGCAACAAAGAGTTCAGAATTAATCACCATCTCATCTCACACATGCGTTGTCACACTGCCGAGCGACCATACAAATGTGAAGTTTGCGGTTCTTCGTTCAGGTTCGCCAGTAACCTGGTAGGGCACATGAAAGTTCACTTGAACCTAGCATCAAAACCGTTCGAATGTGACATATGCGGGGCAAAATTCAGTGCGCAAGGAACCCTCACCGCTCACAGTGATGTTCATCGGCAGGGACAGGCGGCTGAATGCTTTACATGTGATAAACAGTTTCTCACCTCCAGAGAGCTGGAGAAGCATAGGGTTACCATTCACAACTATCGACCGTACAAGTGTACGATTTGTGGCAAAACCTTTGCCACCATGCCGAACTTGCGGTCACATCTGAAAGTTCACACCGATGTGATTCGACTGAAATGTCACATTTGCGAGCGGAGCTATTCAAGGAAATCAAGCCTACAGGCACACGTAAAAGTAGCACACGCTCGAGATGAATTCATGCAATGTAGTGGTATTCAACCGGGTGTCCACTCCAACGAGGAGCCGGATGGTGGTGATGGTACTGATGGTCTCGAAAGGCCCACCAAATGCGACATTTGCGATCGACAATTCGCTAAACTGAGCACTTTCGAACGGCACATACGAACATCCCACCGGTGCGAAATTTGCGGGAAAACCATTGCGCGGAAGGACTCACTCGAAAGACACCGAAGGACGCATACCGGCGAACGACCATTTCCTTGCGACGTATGTGGCAAAAGTTTCGTATGTAAACGCACTCTGATCTGCCATATGACACTGCATACTGGAAATCACAACTACAAGTGCGATTTTTGTGGCAAAGGATACAGTTCAAAGGCTAAGTTTACGATCCACGTGAGATCCCATACGGGCGAGCGTCCACACAAATGTACCATCTGTGGTAAAAGTTTTGCTAGTCAGTTGTACCTGAGAAGTCATACGTTTAGACATGAGGAAAATTACGAATTCAGCTGTGATGTTTGTGGTAAAAGATATGGTACAAGAGCTAAGCTTGAGTTTCACAAGGAAACACACAGCACAACCGAGCGCCCATACAAATGTGACATTTGCGGTAAGGGATTTTCCTTTATTGGACTGCTCAATCAGCATCTGAAATGTCATAATGAAGAACGTCTGCATTCGTGTAATATTTGCAACCAAAAGTTCAGAATTATTCATCATCTCAACTCACACATGCGCCGTCACAAGGATGAACGACCGTACAAATGTGAAGTTTGCGGTGCTTCGTTTAAGGCTTCCAATGGCCTGGTAGGGCACATGAAATGTCACTCAAACCTAGCCGCAAAACCGTTCGAATGTGACATATGCGGAGCAAAATTTAGTCTGCAAAGAAACCTCACCGTTCACAGTGTGGTTCATCGGCCGGGACAGTCCCATGAATGCTTTATATGTGGCCAACAATTTCGCACCCTCAGAGTGCTGGAAAGGCATAGAATCACCATTCACGACTATCGACCGCACAAATGTACGATCTGTGACAAAGCCTGCGGCACCGTGTCGAGCTTGCGGGATCATCTGAAAGTTCACACTGACGTGATGCGACTCAAATGTCCTATTTGCGGGCAAAGCTATGCAAGGAAATCAAGCCTTCAAACACACATAAAAGAAATACACGGTCGAGATAAATCAGTGTAG
Protein Sequence
MRPPHAHLMPRGLIPWLVKQAPNKHRNYSALSKAIYSYDNTGLKKPKCYICDRQFAELRYLKLHMRSTAHAEKVSHPCDICGKIIARKDSLERHRRTHTGERPFSCEICGKSFPCKRSLVNHMRLHTGNHNYRCDVCDKGYSSRSKLMIHLRTHTGERPYKCELCEKSFASQLYLRNHTLRHEENHEFSCGVCGKGCGTGALLAIHEKTHSTERPYKCDICGKEFFAIGQFNRHLKCHNDERLHRCTVCTKEFKNNQHLVVHMRCHTGERPYKCEVCCSSFRFSNNLVEHMKCHLDVASRPFQCGVCGAKFSLQRTLTAHSVVHGHSDDQPDRDGTGLEKPTKCDICDRLITKLGNFKRHMRTHTENTAHRCDICGKTLKWRDSLESHRRMHTGERPFRCEICGKGFACKRTLNGHTKLNAGNHDYKCDVCGKAYSPKCKFVDHMKSHAGERPYECDICGKKFASQCILRNHTLRHTENYEFSCDVCGKGFATRGSLVNHGKSHSTGRPLACDICGKTFYNNQTLRYHSDRHMTEHPFKCNICGKGFSFLGQLNKHWKIHNAPRLHRCNVCNKEFRTKFLLVTHMRSHTDERPYKCEICGSSFRTSTTLVGHMKIHANLASNPFECDVCGAKFSQQRTLSIHSKVHRKTPCHECPNCNKQFLASRDLNRHRVTVHNDRPYKCTICDITTTTMQNLRSHLKVHYGAIRHKCHICGKSYARKSGLNDHVKVVHAQDKRLHSDHELDGDGSELEKRHMGTTNHEKASHRCDICGKSFEKPYVYVRHRRMHTGERPFSCVICGKCFTCQSYLRNHMRLHTENHIYKCDVCGKGYSSKSKFTTHMRSHTGERPYKCDICGKSFASQLYLRNHTLRHEENYEFGCDFCGKGFGTRAKLAVHEEIHSTTERPFKCNICDKGFSFIGQLNQHLKCHNDERLYRCNVCNKEFRINHHLISHMRCHTAERPYKCEVCGSSFRFASNLVGHMKVHLNLASKPFECDICGAKFSAQGTLTAHSDVHRQGQAAECFTCDKQFLTSRELEKHRVTIHNYRPYKCTICGKTFATMPNLRSHLKVHTDVIRLKCHICERSYSRKSSLQAHVKVAHARDEFMQCSGIQPGVHSNEEPDGGDGTDGLERPTKCDICDRQFAKLSTFERHIRTSHRCEICGKTIARKDSLERHRRTHTGERPFPCDVCGKSFVCKRTLICHMTLHTGNHNYKCDFCGKGYSSKAKFTIHVRSHTGERPHKCTICGKSFASQLYLRSHTFRHEENYEFSCDVCGKRYGTRAKLEFHKETHSTTERPYKCDICGKGFSFIGLLNQHLKCHNEERLHSCNICNQKFRIIHHLNSHMRRHKDERPYKCEVCGASFKASNGLVGHMKCHSNLAAKPFECDICGAKFSLQRNLTVHSVVHRPGQSHECFICGQQFRTLRVLERHRITIHDYRPHKCTICDKACGTVSSLRDHLKVHTDVMRLKCPICGQSYARKSSLQTHIKEIHGRDKSV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-