Basic Information

Insect: Tolmerus cingulatus
Gene Symbol: L
Assembly: GCA_959613345.1
Location: OY390708.1:25397289-25403699[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.32 62 5.7 5.7 1 23 21 43 21 43 0.98

2 17 1.7e-07 3.4e-05 25.4 3.1 1 23 49 71 49 71 0.99

3 17 1.4e-05 0.0028 19.4 0.2 1 23 77 99 77 99 0.98

4 17 0.11 22 7.1 0.2 3 23 157 179 155 179 0.86

5 17 0.011 2.1 10.3 0.2 2 23 200 222 199 222 0.95

6 17 0.074 14 7.7 0.5 1 23 311 333 311 333 0.95

7 17 6.9e-05 0.014 17.2 1.3 1 23 341 363 341 363 0.97

8 17 0.0028 0.54 12.2 0.2 1 23 371 395 371 395 0.87

9 17 0.037 7.2 8.6 1.3 1 23 430 453 430 453 0.98

10 17 0.001 0.2 13.5 2.9 1 23 485 507 485 508 0.96

11 17 4.5 8.8e+02 2.1 0.6 1 23 642 666 642 666 0.83

12 17 0.00076 0.15 13.9 4.6 2 23 675 697 674 697 0.96

13 17 0.088 17 7.4 0.1 1 23 703 725 703 725 0.92

14 17 0.54 1.1e+02 5.0 0.3 2 23 733 754 732 754 0.96

15 17 0.98 1.9e+02 4.1 0.5 2 23 838 859 838 859 0.95

16 17 0.00072 0.14 14.0 0.0 1 23 869 891 869 891 0.98

17 17 0.1 19 7.3 0.3 1 23 898 920 898 920 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.32	62	5.7	5.7	1	23	21	43	21	43	0.98
2	17	1.7e-07	3.4e-05	25.4	3.1	1	23	49	71	49	71	0.99
3	17	1.4e-05	0.0028	19.4	0.2	1	23	77	99	77	99	0.98
4	17	0.11	22	7.1	0.2	3	23	157	179	155	179	0.86
5	17	0.011	2.1	10.3	0.2	2	23	200	222	199	222	0.95
6	17	0.074	14	7.7	0.5	1	23	311	333	311	333	0.95
7	17	6.9e-05	0.014	17.2	1.3	1	23	341	363	341	363	0.97
8	17	0.0028	0.54	12.2	0.2	1	23	371	395	371	395	0.87
9	17	0.037	7.2	8.6	1.3	1	23	430	453	430	453	0.98
10	17	0.001	0.2	13.5	2.9	1	23	485	507	485	508	0.96
11	17	4.5	8.8e+02	2.1	0.6	1	23	642	666	642	666	0.83
12	17	0.00076	0.15	13.9	4.6	2	23	675	697	674	697	0.96
13	17	0.088	17	7.4	0.1	1	23	703	725	703	725	0.92
14	17	0.54	1.1e+02	5.0	0.3	2	23	733	754	732	754	0.96
15	17	0.98	1.9e+02	4.1	0.5	2	23	838	859	838	859	0.95
16	17	0.00072	0.14	14.0	0.0	1	23	869	891	869	891	0.98
17	17	0.1	19	7.3	0.3	1	23	898	920	898	920	0.96

Sequence Information

Coding Sequence: ATGCTGTACCTAATCTACTCGAAACGTAATACAACTACAAGCCACGCCGAACATCTTCCCTTTAAATGCGAATACTGCGCCCGCCTCTTCAAGCACAAGCGCTCCAGGGACCGTCACACCAAATTACACACGGGGGACCGGCGCTACCGCTGCCCCCACTGCGAGGCGGCATTCTCCCGAAGCGATCACCTCAAGATCCACATGAAGACGCACGACAACCAGAAACCGTTCCAGTGCACGGTCTGCAACCGGGGCTACAACACGGCGGCGGCCCTCACCTCCCACATGCAGAACCACAAGAAGCAGGCGGCCCTTTTGGGTGGTGGGGCACATGCCCTGAATTTCAGCCCACGCTCGACGGGCAGCGGGTCCAGCAACAGCAGCTTCCACAAGCGGCGGTACGCGACCGCCGAGAACAGCCCGAGCCGCGCCGACTACCGCAAGCACCTCCGCGGCGGCTTCATCTCGTGCGTCTACTGCACCAAGGCGGACTTCGCCTCGCTGGACCAGCTGAACACACACATCCAGACGATGCACGAGAACGCGACGCCCAAAGACAACCACCACGCCCTGGCCGGCCACTCGGTGTTCCAGCTCTCCTGCGAGTACTGCACCATGAAGTTCCCCAACATCCCCGCGATGTTCCAGCACATGAGGGCCACGCACGTCGACCGGCTGGCGAGCCCCAACTCCTACTTCGAGCACTTCAACCGCCTCGCCGCGTCCGGGACGTTCAGTCCGCGACTGGCCACCAGCGTGCGCTTGGATGAAATGAAGGTAAAGACCGAGGAGCCAAGCCCTAAGCAGGAGCGCTCATCAGAAGTAGAAAAGGATGAGGAGCAAGTGAGTCCCACCGACTTGAGTCAGCCCAAAAAGCGGTCGCAAACGCCGCAGACGCAAGGGGCGAGTTCAGCGGAGAAGCCTGGCGCCTTCTTGTGCAACCAGTGCAACGCCGGACTGCCCGACTTCGAGACGTTCCGATCGCATCTGAAGACGCACATTAGCCAGGGCGTTACCAACTTTGTCTGCCACCACTGCGGACTATCGCTGCGTGACCAGGCTGAATATGAGCGGCACATCGTGTCACACTTCCTGATCGCGAGCTCCGAATACGCCTGCGCCAGCAGCTGCAGCAAGGTCTTCCCGAAGCCAGACGACCTCCAGAAGCATTTGTTCGAGAGCCACATCCAAGCGATGTTCAAGTGCTCCCTCTGCTCAGACCTCTTCGAGTCGAAAGTGGCCATCCAGGTCCACTTTGCGTGCGCTCATTCGAACGAGAACAAGATTTTCAGGTGCTCCGCATGCATGGAAACATTCAGAGCGGAAAAGGATTTTACCACTCACATCAGGACTCGTCATGCCAGCACCGGGTCCATCCAGTGCATGTTTTGCAGAGCAGTGTGCTCCTCCGAGCTGGAGATGCATTTCCACCTAGCAGCGCACGCGAGACAATTTCGGTGTCCCTCATGTCCGGAGACCTTCCACGTAGAGTTCCTCCTGGACCGACATATGCAGACCCATCACGCGCAGAAGGATGGAAGCGCAGTGGCCCCAATCACCAATGCTTCGAATCAACTGTTCCAGGGGCAGTTCGCTAAGACCCCtaataacaacaacaatgTCCTGGACTACCATTCCTTCGTGGCGGCGAACAAGAGCCTCTTCCCGCTTCCGAGCAACAAGTTCTACAACCCGCTCCAGGTCGAAACCAGCTCCTTGAACTCCTCCAGCAAACATCCGTCGTTGATGTACGGACTGGGCCAGCGGTACTTCGACACCAACAAGACCCTCCTGGACATGTACAACTACCAGCAGGAGAAGAGTGGGTCCAACTACTTTGTGAGTCCCAGTGGGTTCGAGGGCACCAGGGGTCCGAAGCCCCAGCCCGAAGTGAAAACTCCCGACCGAACCCACAACAGTGGCTTCAGTTGCGGCATTTGCGAGCGCAGCGACTTCCGCACGGAGGCTGAGGTCCACTCCCATCGCAAGATAGTCCACAATCTCAAGACGGGGGTGAGTCTCAGGTGCGCCTACTGCAGCGGCAATTTCAAGTCCCGGAGTGAGCTGGAGCACCACATGAAGACTTGCCACAACTCGACAGGGAAGCACAAGTGCTTGATTTGCGACGAAATCTTCCCGTCGCCGGCCATTTTGGCGGAGCACAAGTTGCAGCACTCGAAAGTGGGGCAATCTGGGAAGTGTTCGCACTGCTCCGCGGCCTTGAATGACGTCGCCGCGTTCAAATCCCACCTGTCCGAGCACAACGTCGAGGGCCAGATTCCGGTGCAGTGCATCTGCTGCCGACAGACCCTCAACTCGGACTTTGAGATTGGACTCCATGCCAAGTTCCACACAAAATCCTCTGGGACGCCCGAGAACCTTTGCGCTCTCTGTCTGGAGGCAATCCCACCCACCTCGGAAGCTCGAGTCTGCGAAAAATGTTGTCGCAAGCACAATCTGACCTCAAAGTTCAACATGCGCTTCGAGTCCTCCCGCAGTTACGTGGAAAATAGGTGCAACCTCTGCAAGATGATCCTACCTCACGCCCAGCGGCTCCAGGAGCACCTCATCGAGCACACGTTCGTCGGGTGCGAGGAGCGCGGCTACTCCTGCTACATTTGCTCGGCGGTGTTCACCGTTCCCGCGGGACTCCTGAGCCACATGAACGAGCACGGCCCCAACGCGCGCCCCTACGACTGCAACCTCTGCTCCGAGAAATACTTCTTCAGGGCGGAGCTGGACAACCACCTGATCGAGCACGAGAACCGCGTCAAGACTGACCTCAAGCACGAGACCCCGCAGGAGCAGCAGCAGATGCCGAAGGAGGCGGCGCCCCCAGCGCAACCCTCAGCAGGACACGAAAAGGGGCCCGAACCGAAGGACTCAAAGAAGGAGGTTGCCGAGGAGGCCCATCTAGAGGTCAAAACTGAGGTCGCCGAGCATGAGAAGGACGAGGACGAGGAGGAGTACATCgaagttgaaaaaattccGGAGACTTCTGCCCCCGAGGGGGGCCAGAACCACCAGCACGACGACTAG
Protein Sequence: MLYLIYSKRNTTTSHAEHLPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQNHKKQAALLGGGAHALNFSPRSTGSGSSNSSFHKRRYATAENSPSRADYRKHLRGGFISCVYCTKADFASLDQLNTHIQTMHENATPKDNHHALAGHSVFQLSCEYCTMKFPNIPAMFQHMRATHVDRLASPNSYFEHFNRLAASGTFSPRLATSVRLDEMKVKTEEPSPKQERSSEVEKDEEQVSPTDLSQPKKRSQTPQTQGASSAEKPGAFLCNQCNAGLPDFETFRSHLKTHISQGVTNFVCHHCGLSLRDQAEYERHIVSHFLIASSEYACASSCSKVFPKPDDLQKHLFESHIQAMFKCSLCSDLFESKVAIQVHFACAHSNENKIFRCSACMETFRAEKDFTTHIRTRHASTGSIQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQTHHAQKDGSAVAPITNASNQLFQGQFAKTPNNNNNVLDYHSFVAANKSLFPLPSNKFYNPLQVETSSLNSSSKHPSLMYGLGQRYFDTNKTLLDMYNYQQEKSGSNYFVSPSGFEGTRGPKPQPEVKTPDRTHNSGFSCGICERSDFRTEAEVHSHRKIVHNLKTGVSLRCAYCSGNFKSRSELEHHMKTCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCSHCSAALNDVAAFKSHLSEHNVEGQIPVQCICCRQTLNSDFEIGLHAKFHTKSSGTPENLCALCLEAIPPTSEARVCEKCCRKHNLTSKFNMRFESSRSYVENRCNLCKMILPHAQRLQEHLIEHTFVGCEERGYSCYICSAVFTVPAGLLSHMNEHGPNARPYDCNLCSEKYFFRAELDNHLIEHENRVKTDLKHETPQEQQQMPKEAAPPAQPSAGHEKGPEPKDSKKEVAEEAHLEVKTEVAEHEKDEDEEEYIEVEKIPETSAPEGGQNHQHDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00628637;
90% Identity: iTF_00718036;
80% Identity: -