Basic Information

Insect: Tipula vernalis
Gene Symbol: Hivep1
Assembly: GCA_958295665.1
Location: OY282560.1:90777807-90787012[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00084 0.47 14.3 2.1 1 23 359 381 359 381 0.97

2 8 0.00054 0.3 14.9 2.3 1 23 387 411 387 411 0.90

3 8 0.003 1.7 12.5 0.4 1 20 717 736 717 737 0.95

4 8 3.5e-06 0.0019 21.8 2.0 1 23 1500 1522 1500 1522 0.99

5 8 3.8e-05 0.021 18.5 3.2 1 23 1528 1552 1528 1552 0.92

6 8 0.0049 2.7 11.9 1.8 2 23 2008 2029 2008 2029 0.97

7 8 0.0065 3.6 11.5 1.3 1 23 2035 2059 2035 2059 0.91

8 8 0.0058 3.2 11.7 2.6 1 23 2080 2104 2080 2104 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00084	0.47	14.3	2.1	1	23	359	381	359	381	0.97
2	8	0.00054	0.3	14.9	2.3	1	23	387	411	387	411	0.90
3	8	0.003	1.7	12.5	0.4	1	20	717	736	717	737	0.95
4	8	3.5e-06	0.0019	21.8	2.0	1	23	1500	1522	1500	1522	0.99
5	8	3.8e-05	0.021	18.5	3.2	1	23	1528	1552	1528	1552	0.92
6	8	0.0049	2.7	11.9	1.8	2	23	2008	2029	2008	2029	0.97
7	8	0.0065	3.6	11.5	1.3	1	23	2035	2059	2035	2059	0.91
8	8	0.0058	3.2	11.7	2.6	1	23	2080	2104	2080	2104	0.93

Sequence Information

Coding Sequence: ATGTTTGATAGTGGCCCGATGAGAAAGGatGATTCAGATGATAGAGGTGACAAACCAGTAGCACCATTAATCGATatagtacaaaaaaataatagtagtagtaataataataataacaataatgaaatagatgCAAGGCAGAATCGAAGGGATgaggaattattaaaatcacatcATATTCATAATCAGCACCAATCAACAAGGGAACTTCCaacatatgtaaataataataacaatagtaGTGCAACATTTGATGATCTAAAGTACctgcataaaaaatttaagcgacTCGCTAGTACGACACTAAATGATACAAATTTAGGGAAAATCGGTTTAGTGAATATTAGTAATTTAATAGTGAATAGTAAcagtagtaatagtaatatcaGCCCACCATTATCAACTTTTACATCAACATCATCACAATCGCCTCCCATTGTTGCGTCTgcaacaccaacaacaacaacaacaatcgcGCCAACAACCACATTAATATCTCCACCCAATATACAACATATTCAACACAAGAAATTACAGTACAGTGAGTCCGACAATTACAACCAGGTTCAATTAATGAGTAGCACAAGCAACAGTAGTTCCAAATATAACGGACGTCTAGAAAATGATTATGTGCAAAGTAGTACCAGTAATAATCAAAATGAGTTGAGgtataatgataatattaccaACCAGCTTGCATCAACCCAGCAACATGTCGTTGAAGCAAGTGGTAATAATGTAATTTATGTCCCTCTACGACCTACTACACATTCGATTCAACAAATCCCGCCTTCACAATCACCATCGATATTGTCACAACAGATCAATTACGTAAAACAGCAGCAGGTGCCATCGATTGATGGTATTACAGCGTCAAACATGGGTATGAATGATAATTATAGCCACCAAAATCATTACCAACCACATAATATACCGAATGGTATTTTAGCGCACGGAAATTCTACGGTGTCATCAACAACGCTGATTTCAGCTCCAAAAGTTATAACTTTAACACCAAGTACAATGCCGCCTGGTACAGCGCTCTCAACAGCACCTTCATCTACCAATGGCCGGCACGTATGCCCTTATTGCCAAATGAATTGTTCAAAACCGTCTGTCCTTCAAAAACATATACGAGCCCATACAAATGAGCGACCATATCCTTGTGGACCGTGCGGTTGTGCatttaaaaccaaaagtaaTCTCTATAAGCATCAAAGGTCACGTACACATACTCTACGAACCCAAGGTGGTGAAATAGCGGATGATGATGTTTCACAAAGCTCCGATCAAGAGCAAGATCAAGATCAACAATATAatcaacttgaaaatttggccCAACAACAAAATTCCACTATGGAAGTTGATATGAAATATTCATCACAACAACATGTACACCAGCCACCATTACAGAACCACCAACTACATCATCAGCCTGCCCAAGAGAAACCGtacaaaccaaaatttcacAATGCTTATAAACCGTATGGTGACCAAGGGAATAGTAACAGTAGTAGTTGTAGTGCTTCCACAAAAGATGAGATGAAACAACTAAATTATGTTGCGTCAATGAGTACAAATTCGAGCGGAAATTCAGCTGCAACGTTGAAACAACATCATGTTTCAAATTTAGTCtCAACTCCACCAAAAAATGTAGATGTTGCTTTACACATTACTAAATTAATATCGGATAATGAAGCAATTGTCGAAGGTGGTAAACCGCCATTACCAAAGAAAACTCTAAAATCATTTCGGAGTGTAATTCCAGAAAATTCGAGCCCAAAATTAGCCCTTGCTTTGTTGCATAAGGAAATAAGTGCAAACGCAGCCGGCCAAATGACTAACAATAAATTAACGATTTCTAATAGTCGTATTCAAGGTAGTCATACTGCATATACGAATTTTTCGACTGGTACAAATCCGGGTACATCGAATCAGGCATCTACCAGTTCTGGAAGCCAACCGTTAAATTTGAGTAAAGTAGTGAATGACAATGATGTGTCGCGAAAAAGATGTTTTAGTGAAAGTTTTACAGGCCAAGATGTGGCGAATCATCCGCAAAATCCTGAACGATCTATTATAAAAGATTTACTTTTGAATTCGAAAGGGTTTGGTGCTGTAGCCGATAGTGAAGCAGCCGAATCATTGTATAATTgtccattttgtaaaattagttttcgaAACGCTGAGACGCTGAAATATCACACGATATGTTATTGTCAAGGGAATCAAGCGAACAGTCCACAAAGTACACCAGCTAGTCCAGCAGCTTCTCCATCTCATCAGTATATGAGATCTCATTCTAATTCAGGAAGTTATAATCCGAATAGTTTAGCAAAATTGGCTAGTACCTCACTGCGCCAACATCCATACCGTACTCCTACAAAATTGTCCAATTTAGCAAAAGTTAATATAAAGCAAACACGACCGAGACTCGAAAATATCGTGATTAATACCGTAATAGAGAAACAAGAAGAAATTGTAAATCGTAATGTGGAAATTGTACAAGCCCCATTGCCTTCGCCGGGCCCTCTATTGGGTAAAACTCGTCTTGTTGATTCTTActataaaacatcaaatttgATTGAGGAAAAAACAGACGATGTTTCTTTGTACGTTGTTGAAATAAATCGGGAGCGGAGCCCATCTCCAGTGGATACACCTAGTCACAATTTTGCTCTACCCACGATGATAAGTGAAGATCCGGCAATGTCTCAACGAAGGAGCTCGAGTAGCGTGAATAATTTTCAGATGTTTGGCGGGGAAGTTCAAGTGATCGAGAAGAAGAATGATTTGTTTCCTACCTATGGTGCTGGTGGTTCAGTAACATCTTTATCACCGTCTGATTCAGAACCCAGCCCAATACTTGTGCGTTCAGGGTTATTTTCTGGTGGGTCGTTACAGTTACCGCATACacctaaagaaaaaattaatcgcACACCTTTAACACCAAAACTACTTGGTACCCCGTCATTGGTTACACCATCCTCGGTAACACATTTTCAATTTCCACCGATTAATTCGATATCAGGTTACAATCCGCTGACCTTACCGCCGATTACGATTTCTTCGATATCATTACCAAGTTCGTCCCCGATGTCTACACCATCATCAAATCAGCCATCCGCCATTATTCATGGTGGTAAAATCATCCCATTTGTACCAGGAATGCCTGGGCCAAACACAAATTCAGCGTCAAATTTAATTCACCAACAACAGCATCTAAATAATAAACGAGTGATCAGTCCAAATCGATTAAAAAACATCCCAAGCCCGTTGACGTATACGCACGCCTCGAATAATTCAATGCATTCTGGAACATCAGTACTTCGTATAAATACCGGGCTTCCGAGTACAAATATACCAAATAATGTAATATCGCCACGGACGATACCtcatattaaaatttacgaCGGTTCCACAATTATAAGCGACGAtacaataaaagtaaataaaaagccGGTcgcaattggaaacaaaaacgGATTATTGGTAACCACcgataagaatttaatttggtcaCCGGCAAAGCAAGAAATACAATCGTCAAGTTCTAGcactagaaaatttaatttcgctaGAATGGCAGAAAACTTGAGTCCACGTAAATTAAATTCAGCATTACCTCCGGGGCGATCACCTGATGCGGAAATTCGTCATTttaattacgaaaatttaatttcaaaatcagcGATTTTAATCAAACCACCTCCGCAACCAGCTACTCATCTACAAGAGGCCACTCGAACTTCAGCTATAATTCCAATTCATGTTGAGGTTGATCCATCACCTCCGCGATCACCACAACCTCcggctaaaaataaatttctacgACCCACTTCGCTTCCATTGAAACCAGGTACTTTTATACAAAAGAAACATCATGGAATAACACcaacacaaaacacaatgccACTCATTTCACCGGAAACTCCGAGGCCATCGAAAAATTGTATCCAGCTGTATTTAAATGGACATGCTTACACATATCTTGGCCTCAAATGTAGTACAAAGTTGACTTATTGCACCCTAAATCGGGCACAACCTGTTTATATTGCGAACCAGCATAAACTGTCCATGTACAGCGAATGGCGAGTACAAACTGACTATGATCCGCATCCATTAGGATTGAAGCAAGACAAAGCAATATCTTTGTACGATTCCCGACATAGGCCGCTTTCATATTCAATTGCTAAGGATAGGACACGGCTTGCATctcaaaatacatatttggtgCATTCGCAATCTACAATAATGACACCATTCGAAAGTACTATGCCTGCATTGAAGGATGGACAGTTTCCGCATCATCAAGTTATGCAGATTGAAGTACCGCAACCACCACAACCTTTAGCTAATTgtgaaacaacaaatatgtatgtTACAACGACTGGACCTATCTCATCATCGAACTCATCTTCGATTGTGGGTACGATCCCTGGCGGTTACGAAAGTAATGAagattatacatatgtacgggGGCGAGGGCGAGGTCGTTATGTTTGTTCCGAATGTGGAATACGTTGTAAAAAACCGTCAATGCTTAAAAAGCACATTCGAACGCATACTGATGTACGGCCATACACTTGTAAGATGTGTGCATTTAGTTTCAAGACCAAGGGGAACCTTACTAAGCATATGAAATCAAAGACTCATTATAAAAAGTGTATAGAACTAGGATTGAATCCGATTCCATTGCAAGGTATGAACATGGATGATGATTCAAACGAAATGCTAGACGATCAAATGTCTATGACTGGAAGTGGCCGTACAAGTACAATACCTGGAGATTCAGATACAGATTCGGATAGTGATGGAGACGATGTCGAAAGTGAAAGTAGTGatacCGACGAGTCTAAATCACGTCTTCTTGAACAGGAAGCAGCACActgtttaatttctttatcaATGACCCCTCCTATTCCTTCGGTAAGCACTACAAATTCATACAGTCAGCCACCAATTGATGCATTGGAAAATCGACAGCGTTGTATTATTACAACGTTTTCATCGGCCAAGCCAAACGAATTCAATCTTTTAAAACATGATCAATACTATTCGAACCCAAAAGTGAATAAAGTTTATAATGTGGTCCGAAATGCCGTACCCGAAATGGTTCCTTGTGATATTCCATCATCAGCCACAGATGATTCAATGCCTATTGATTTGACGAAGCCGAAAGAAAGGGAAAGACCAGTAGTTTATAGTAATCCCCAAAGTTTAATACATCAAGCAACGGTTCAGGTACGTCCAGAAATTTCAGAAGTAATCGGACCAATTGATCAGACTCGATTTATCACATCGCTCGTTTCGATTATGGAGAAAACCCCTACGTCATCTAGTAGTATTGATAGTAATAACTTACCTAGTCATATTGATGAGAATAAGTTGTTACATCAATATTTGACTGAGCGGGCTCTgcaagattctaaaatgaaacaGTCCCAAatgataaagaaattaagtaacATTGAGAATTGTGAAACGAATACAAATAGCAGTGATGGTATAGTCGGAGGAAATGGAATCATTATTTTAAGTCAACCATCAACACCATTGGCATCAACACCAACTAATTCTGATTATTTCGGTACCAAATATGATGAAAAAATAATGAGAAGTTATGATACAGAAAGTGAAAAACAATCGAATCACAGTGAAAATGAAAAGGAGGTGGGAAATGCTTCGAGTATGGAAACATTGGCTGATGTTGCAGCAAGTTCTGTTAAATTAGATGTTTCCAgtaatcaaaaaatgttgaacataAATGATAATGCTAAAACTGTGGCATCAGAATATCTAAAGCTCGCTTCTAATGAGACCAGGCGACAAGCAAAAATTTCTATCAATGAAGATGATGAGTTTAACAATAGCGAATCGGATCAGGatgatttatcaaataaaatgtcgAATACTAATATGGTGCGGAAAGTGGTGGTCGGTGAAGATGGTTTTAAGAATCCGGTCGCTGAAAATACACAAGTTCCTTATAAACCACGGCTTCTTGAAGATGGTCGGGCTGTTTGCACGGTTTGCTCGAAAACATTTCAGAAAGAATATCATTTGCTATTGCATTATAATATTCACTATATCGAGAGGAAATTCCGTTGCGAACCATGTGCTATCAGTTTTCGTACAAAAGGCCACTTACAAAAACATGAACGTAGTGTTCAACACAATACCAAAGTTTCAATGACATCAACGTTTGGCGTGGCAACCACATCAAATCCACGTCCATTTAAATGTGGTGATTGTAAAGTTGCGTTTCGAATACATGGACACTTGGCAAAGCATTTACGTTCGAAAAGCCATGTCATGAAATTGGAATGCATTGGAAAGTTACCGTTTGGTATGTACGCTGAAATTGAAAGGGCCGGTGTTAGTTTAACCGATATTGATACAACTGACTGTGATAACTCATTGACAAGTTTATTATTGCTTGCCCAAAAATTACACGAAAAAGATCCGAATATATTTGGTAATTGGAGTCCAGacgtaaataatatttcaattttacaacgacaacaacaacaacaacaacagctaCATAATAGTAATAagaatagtaatagtaataatgaTACAGACAGTGAAGACAGTGATAACCAAATTGATGAACAAaaagatgaaattaatagtCTTAGTCGTAATATGAGTAATATGAGTAGTAGTGTTGGTGGtggattaataaatattattagtaataatATAAGTAACAGTAATTCTATAAGTGGTGGAAATGGTGGAGGTGGTGGTGATTCAGCATTTTCATCTGACTCAAGTACTGGTTCGATAAAACgtaaaattgatcaaattacCGGGAGTCTAGATCCTCTACTTATCGGCAGCGATGAGCAAGcgccatcaccatcatcatcctTAAATATCGATCATAAAAGACTTAAAACACTAAGTGACATCTAG
Protein Sequence: MFDSGPMRKDDSDDRGDKPVAPLIDIVQKNNSSSNNNNNNNEIDARQNRRDEELLKSHHIHNQHQSTRELPTYVNNNNNSSATFDDLKYLHKKFKRLASTTLNDTNLGKIGLVNISNLIVNSNSSNSNISPPLSTFTSTSSQSPPIVASATPTTTTTIAPTTTLISPPNIQHIQHKKLQYSESDNYNQVQLMSSTSNSSSKYNGRLENDYVQSSTSNNQNELRYNDNITNQLASTQQHVVEASGNNVIYVPLRPTTHSIQQIPPSQSPSILSQQINYVKQQQVPSIDGITASNMGMNDNYSHQNHYQPHNIPNGILAHGNSTVSSTTLISAPKVITLTPSTMPPGTALSTAPSSTNGRHVCPYCQMNCSKPSVLQKHIRAHTNERPYPCGPCGCAFKTKSNLYKHQRSRTHTLRTQGGEIADDDVSQSSDQEQDQDQQYNQLENLAQQQNSTMEVDMKYSSQQHVHQPPLQNHQLHHQPAQEKPYKPKFHNAYKPYGDQGNSNSSSCSASTKDEMKQLNYVASMSTNSSGNSAATLKQHHVSNLVSTPPKNVDVALHITKLISDNEAIVEGGKPPLPKKTLKSFRSVIPENSSPKLALALLHKEISANAAGQMTNNKLTISNSRIQGSHTAYTNFSTGTNPGTSNQASTSSGSQPLNLSKVVNDNDVSRKRCFSESFTGQDVANHPQNPERSIIKDLLLNSKGFGAVADSEAAESLYNCPFCKISFRNAETLKYHTICYCQGNQANSPQSTPASPAASPSHQYMRSHSNSGSYNPNSLAKLASTSLRQHPYRTPTKLSNLAKVNIKQTRPRLENIVINTVIEKQEEIVNRNVEIVQAPLPSPGPLLGKTRLVDSYYKTSNLIEEKTDDVSLYVVEINRERSPSPVDTPSHNFALPTMISEDPAMSQRRSSSSVNNFQMFGGEVQVIEKKNDLFPTYGAGGSVTSLSPSDSEPSPILVRSGLFSGGSLQLPHTPKEKINRTPLTPKLLGTPSLVTPSSVTHFQFPPINSISGYNPLTLPPITISSISLPSSSPMSTPSSNQPSAIIHGGKIIPFVPGMPGPNTNSASNLIHQQQHLNNKRVISPNRLKNIPSPLTYTHASNNSMHSGTSVLRINTGLPSTNIPNNVISPRTIPHIKIYDGSTIISDDTIKVNKKPVAIGNKNGLLVTTDKNLIWSPAKQEIQSSSSSTRKFNFARMAENLSPRKLNSALPPGRSPDAEIRHFNYENLISKSAILIKPPPQPATHLQEATRTSAIIPIHVEVDPSPPRSPQPPAKNKFLRPTSLPLKPGTFIQKKHHGITPTQNTMPLISPETPRPSKNCIQLYLNGHAYTYLGLKCSTKLTYCTLNRAQPVYIANQHKLSMYSEWRVQTDYDPHPLGLKQDKAISLYDSRHRPLSYSIAKDRTRLASQNTYLVHSQSTIMTPFESTMPALKDGQFPHHQVMQIEVPQPPQPLANCETTNMYVTTTGPISSSNSSSIVGTIPGGYESNEDYTYVRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPYTCKMCAFSFKTKGNLTKHMKSKTHYKKCIELGLNPIPLQGMNMDDDSNEMLDDQMSMTGSGRTSTIPGDSDTDSDSDGDDVESESSDTDESKSRLLEQEAAHCLISLSMTPPIPSVSTTNSYSQPPIDALENRQRCIITTFSSAKPNEFNLLKHDQYYSNPKVNKVYNVVRNAVPEMVPCDIPSSATDDSMPIDLTKPKERERPVVYSNPQSLIHQATVQVRPEISEVIGPIDQTRFITSLVSIMEKTPTSSSSIDSNNLPSHIDENKLLHQYLTERALQDSKMKQSQMIKKLSNIENCETNTNSSDGIVGGNGIIILSQPSTPLASTPTNSDYFGTKYDEKIMRSYDTESEKQSNHSENEKEVGNASSMETLADVAASSVKLDVSSNQKMLNINDNAKTVASEYLKLASNETRRQAKISINEDDEFNNSESDQDDLSNKMSNTNMVRKVVVGEDGFKNPVAENTQVPYKPRLLEDGRAVCTVCSKTFQKEYHLLLHYNIHYIERKFRCEPCAISFRTKGHLQKHERSVQHNTKVSMTSTFGVATTSNPRPFKCGDCKVAFRIHGHLAKHLRSKSHVMKLECIGKLPFGMYAEIERAGVSLTDIDTTDCDNSLTSLLLLAQKLHEKDPNIFGNWSPDVNNISILQRQQQQQQQLHNSNKNSNSNNDTDSEDSDNQIDEQKDEINSLSRNMSNMSSSVGGGLINIISNNISNSNSISGGNGGGGGDSAFSSDSSTGSIKRKIDQITGSLDPLLIGSDEQAPSPSSSLNIDHKRLKTLSDI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01456847;
90% Identity: iTF_01456847;
80% Identity: -