Tver081606.1
Basic Information
- Insect
- Tipula vernalis
- Gene Symbol
- -
- Assembly
- GCA_958295665.1
- Location
- OY282559.1:126286331-126287757[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.082 46 8.0 0.5 1 20 195 214 195 216 0.95 2 8 0.00021 0.12 16.2 0.4 2 23 226 248 225 248 0.92 3 8 0.00025 0.14 16.0 0.1 3 19 257 273 256 276 0.94 4 8 3.8e-05 0.021 18.5 2.9 1 23 290 312 290 312 0.98 5 8 0.09 50 7.9 5.8 3 23 318 338 317 338 0.98 6 8 1.9e-05 0.011 19.5 1.2 1 23 344 366 344 366 0.97 7 8 2.9e-07 0.00016 25.2 0.4 1 23 372 394 372 394 0.97 8 8 0.067 37 8.3 1.6 1 23 400 422 400 422 0.98
Sequence Information
- Coding Sequence
- ATGACTGACCAAATTTGCCGGTTCTGTTCTCGCGATGATCAACAGGAACTGCATCCCATTGCTATAAATTCATCAATTAATAGATTTTGTCAAATATTAGCagtaaaattcataataatggAAGAACGTTTACCACAGTCGATTTGTTCCTTGTGTGATTTAAAAGTCACGGAAACGGTTGATTTCTACGATCGAATTATAGAATCTGATCGCCTGTTAAGAGCCAAATATCGTCTGCCAACCGAGAACAATAGTTTACGTACGGATTGCAAAAATAGGGGCTCTTCACAGGACGACCTGGTGGGTGCCATTGTAAGCaacattaaaacaaaaggaAACATAAGTATTGCCAAAATTTCAGTAATCCcggaagaaaaattaattaaaagagagCCAAGTCCGTTCTTCTGTGAACCAAATTCGATGACACGTTCATCTATAAGTGAATCgacggatgaagaagaaaattatGATGAATCGCAGTCAGATGAcagcgattatgatgaaaaacCTGCGACTCGTCGTAAAAAATCAACCTCGAAACAAAGTAAAACAACAATTGTCGAAATTATCGAACCAAAATACGTTTGCGCCCGGTGTCGAGGAAAATTTGCCACCCTCGACAATCTACACGAGCATTTAGATCACAGCATCACGTGTAAGGATAAAAACGTGAAATGTGATCCGTGTGATAAGGTGTTTAGTACGCGACGCCAATATCAGAAACATGTCAACGGGGTCCATCGGAAAAAGGTCATAACCAACATATGCGAACAATGCAAGCGAAAATTTACAACTCCGGCAGATTTGGAGAGACACAGTGCCATCTGTACCGGTGATTTTGGCGAAGAACGATctggaattttattcaaatgtaggGAATGCTATaaaacgtttaacaaaaagaacGAATTGATGgaacacataaaaaatcatccgCTGACTCTGTTGTGTGAAACATGCGGCAAAGCGTGTGAAACGCGAAAGcaatatcatcaacataaaagcAAGCACTTGCATTTGAAACCATACAATTGCGACTCATGTGATAAAAGCTTTGCAACAAGAACTCTTCTACTTGCCCATCAGCATGTTCATACTGGTATAAAGCGTTACGTTTGCGACATGTGTGGTAAATCGTTTGCTAAAAAGTCTTCGCTTACTGCTCATAATCGGGGGCATACGGGCGAGAAGCCATATCAGTGTCGAGAGTGTATGGATAAATTTCCAACACTCGATCGGCTTAAAAACCATTTGAAAAAGCATCAGGAAAATAATTGCTACGTCTTTAACTAA
- Protein Sequence
- MTDQICRFCSRDDQQELHPIAINSSINRFCQILAVKFIIMEERLPQSICSLCDLKVTETVDFYDRIIESDRLLRAKYRLPTENNSLRTDCKNRGSSQDDLVGAIVSNIKTKGNISIAKISVIPEEKLIKREPSPFFCEPNSMTRSSISESTDEEENYDESQSDDSDYDEKPATRRKKSTSKQSKTTIVEIIEPKYVCARCRGKFATLDNLHEHLDHSITCKDKNVKCDPCDKVFSTRRQYQKHVNGVHRKKVITNICEQCKRKFTTPADLERHSAICTGDFGEERSGILFKCRECYKTFNKKNELMEHIKNHPLTLLCETCGKACETRKQYHQHKSKHLHLKPYNCDSCDKSFATRTLLLAHQHVHTGIKRYVCDMCGKSFAKKSSLTAHNRGHTGEKPYQCRECMDKFPTLDRLKNHLKKHQENNCYVFN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01456837;
- 90% Identity
- -
- 80% Identity
- -