Tver117088.1
Basic Information
- Insect
- Tipula vernalis
- Gene Symbol
- vars1
- Assembly
- GCA_958295665.1
- Location
- OY282559.1:370324815-370330675[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.00084 0.46 14.3 1.4 1 23 1240 1262 1240 1262 0.98 2 9 0.00028 0.16 15.8 0.2 2 23 1269 1291 1269 1291 0.94 3 9 0.0046 2.5 12.0 0.6 1 23 1298 1323 1298 1323 0.94 4 9 5.8e-05 0.032 18.0 0.5 1 23 1335 1357 1335 1357 0.94 5 9 6.7e-05 0.037 17.8 2.9 1 23 1363 1385 1363 1385 0.98 6 9 0.0048 2.7 11.9 1.1 1 23 1391 1413 1391 1413 0.98 7 9 0.017 9.5 10.2 0.2 1 23 1419 1442 1419 1442 0.96 8 9 0.00036 0.2 15.5 3.6 1 23 1448 1470 1448 1470 0.99 9 9 3.7e-06 0.0021 21.7 1.3 1 23 1476 1498 1476 1498 0.97
Sequence Information
- Coding Sequence
- ATGACGGATGAACAAAATGCCAGTGAAACTGCCGAAGGGACACCACAAGAAAAATCGGCAAAGCAGTTGGAAAAGGAGGCCAAAAAAGCGGCTAAGCTAGAAAAATTGCAACAGAAATTGGATAAAAAGACGACGGAACAGCAAAAAAACACTGGAAAAGAAAAAGTTGAGAAAAAAGTCAAGGAGATTAAAGAAACCATTGTATACACTGGAAACACAGCTGCGGGTGAGAAAAAAGATATTTCTGGAAGTATTCCGGATGCGTATAGTCCTCAATATGTAGAGGCTGCATGGTACAGCTGGTGGGAAAAACAAGGATTCTTTAAGCCGGAATACGGTCGAAAATCAATATTAGATGAAAATCCAAAAGGAAAATTTGTTATGGTTATTCCACCGCCAAACGTAACTGGATCACTACATTTAGGTCATGCCCTTACCAACGCCATTGAGGACGCACTAACAAGGTGGCATCGCATGAAAGGATGTACAACGCTTTGGGTGCCGGGTTGTGACCACGCTGGTATTGCGACCCAAGTTGTAGTAGAGAAAAAATTATGGCGTGAACAAAAACTCACGCGACATGATTTGGGCCGAGAGAAATTTATTGAGAACGTTTGGAATTGGAAACGTGAGAAAGGAGATCGGATCTACGAACAACTCAAACGTATCGGATCGTCTTGTGATTTTGAACGAGCAAACTTTACAATGGACCCAAAATTATGCAATGCAGTAAATGAGGCATTTGTTCGACTTTACGAAGATGGAAGCATCTATAGGAGCAGCCGGCTTGTTAATTGGAGCTGTACGCTTCGTTCAGCGATCTCGGATATTGAGGTCGATAAAGTAGAACTACCAGGTCGAACATTCCTCTCAATTCCAGGCTATCCCAATAAAATAGAGTTTggtgttttaatttcattcgcATACAAGGTCGAGGATACGGATGAAGAACTTATAGTTGCGACAACTCGTGTTGAAACAATGCTTGGAGATACCGCAGTGGCAGTCCATCCTAATGACGCCCGCTACAAACATCTTCACGGTAAATTTGTTGTCCATCCATTCACCGACCGACGCATCCCAATTGTAATTGATGATTTTGTGGAAATGGAATTCGGTACCGGCGCCGTAAAAATCACACCTGCTCATGATCCAAATGATTATGAAGTTGGCAAACGGCACAATTTACCTTTCATCACTATATTCGATGATGATGGTATCATAATCGGAGATTACGGTGAATTCACCGGAATGAAACGATTCGATTGTCGTGTCGCAATACTCAAGGCCCTAAAGGATCGGGATTTATATCGTGAAACCAAAGATAACCCAATGGTTGTTCCCGTGTGCAGTCGATCAAAAGATGTCGTCGAGCCACTTATCAAACCGCAGTGGTATGTCAAATGTGATGATATGGCGAAGGCCGCGACCGAAGCGGTGCAATCGGGTGAACTCAAAATTATTCCAGACACATACGAAAAAATCTGGTACCATTGGATGAATGGAATTCGCGATTGGTGCGTGTCACGGCAATTGTGGTGGGGGCATCGCATCCCAGCTTATTTAGTGCGATTCAATGATGAAAGCAAAACACCTAAAAATTTGTCGGAAGATGCATTCTGGGTCGTGGGTCGAAATGTGGAAGAAGCGTTGAAGAAGGCggccaataaatttaatattgccaAGAGTGAAATTACATTAAAACAAGATGACGATGTACTCGACACATGGTTCAGTTCGGGTCTGTTCCCATTCTCGGTATTTGGATGGCCCGAAAATACGGACGAACTTAAAGCATTCTATCCGACAACATTACTCGAAACCGGGAATGATATTATCTTCTTCTGGGTGGCCCGCATGgtattttttggacaaaaattacTCGGAAAGTTACCGTTCAAGGAAGTATTCTTGCACGCAATGGTGCGTGATGCTCATGGTCGTAAAATGTCAAAATCGCTAGGAAATGTAATCGATCCGATGGATGTGATCATGGGAATTGCGTTAGAAGATTTACATGAACAATTGTATGAATCAAATTTGGATCCTAAGGAAATCGATAAAGCTAAGGCCGGTCAGAAACAGGATTATCCGACCGGAATTCCAGAATGTGgaACGGATGCGATGCGATTTGCATTATGTGCTTACATGTCACAGGGCCGAGATATCAACCTGAATATTCAACGCGTGCAAGGATATCGATTCTTCTGCAATAAACTGTGGAATGCTACCAAATTTGCACTTCTCTATTTCAACGATACGGAAAAATACGATCCCATTGTAAAATTAACGGGAACCGAGAGTAATGTAGACTTGTGGATTTTATCCCAACTCGCTAAAACAATCGACCTTTGCAATACTGGATTTAAGCAATATGAATTGGCTGCGGCTACGACCgcatgttataatttttggctGTACGAATTATGTGACGTTTATTTGGAATGTTTAAAACCTGTGTTTCAAGCGGCGGATGGTGATGATAAAAAAGTGTCTGCGCGTAAAACACTTTATACGTGTTTAGAATTgggcttaaaattaatttcaccatTCATGCCGTTTATTTCTGAGGAGCTGTTCCAACGTTTACCTCGAGCTGAGACAAAAACGCCAAGTATTTGTGTGGCTGAGTATCCCGAAACGGAGAAATTCAATTGGCGCAATGAGCCGTTGgaaaaagaatttgaatttgtgcaAAGGATTGCGAAAATAATTCGATCGGCGCGAAGTGATTACAATTTGCCGAATAAAATAAAGACCGAGATTTATGTGGTGTGCTCGGATCCTGAAATTTTATCAAGTTTGGAGAAATTCAACGGTGATTTATTGGTGTTATCCTTCTGCTCGACGTTGAAATTGAACGAGGAACCACCAGTCGGTTGTGCAATCTTAACAATTTCGGATAAATGTGTTATCCATGTAGTGCTCAAGGGCCTTATCGAGGTGGACAAGGAAATTTCTAAATTGGAAAAGAAACAGGAGTCATTGAATCAAACTATTGGGAAATTGGGTCAAGCAATTGCTGATCCAACGTATGCGACAAAGGTACCAGAAGAAATACGACTACAAAATACAGAGAAAATGACTCAATCTGAAGGTGAATTGGAACGTGTGATTGCTGCTATTGCTACTTTAAAAACTATAACCAGAGGAACGGTATATAATACCGAAATGAGCTTAGAATATCCCAGAGAACTAGAATATAAACACATTGATTTAAAACAATGCCGGTGCTGTATGAAAAGTGAAGATTATGAAAATATGCGTTTAATATACGAGAGAAGTAATAAAGAAATAGCCGACATGTATTGTAAATATACTTCGATTGAGTTGAACCGCGATGATGGATTGCCACAAGAAATATGCACAACGTGCCTAATTACATTTATCCGTTTCCATGAATTTTGTGTGATGTGTTCCAAATCGGATACCGTGTTTCGGGAACAAAAACGGCTGATGAGCAATACAGTGAAAGTGGAAGAAACTGATGATGAATCTCAAATTAATGTGGTAGATGTAGATGAGGAGCCGGATCCGATAAAAATTGaaccaataaaattggaaaGTGATTTTGAACTTGGCATAATAAATGAGGAAAATGAGAGACATTCAGAGGaggatgatgatgttgatggtgGGGTATTCGATCAAGAAGAGTCTGTACACGAGGATATTAAAGATATTAAGCCTAAACCAACGAAACAAATTAGTAGAATATTTCCGTGCTCGCAATGTGATAAAAAATTCTATCGTGAACGTCGATTGGAAGGTCATCTGCGACAACACAAAGGACTTAAACCGGCAGTGTGCACTATCTGTGACAAAGAATTTTCTAAATGGACCGCCCTTGACACACACATTCTGTACTCACACAACAATGCTGAAAGAAAATTCATCTGTGATGAACCAGACTGTGATAAATCGTATATGATGAAGCAATCGTTGACGACACATAAAAAGCGGGTCCATTCAAAAACACCGGACCTAAAACCAGAATCTACATATATATGCGAATTGTGTGGCAAATCTTTTGCCACGACAGCAACGCTAAAGAAACATTCGTTTATCCATAGTGGACAACGACCGTTTGTATGCACCCTCTGTCCGAAAAAGTATATCACCAATCACAAACTCAAGGAGCACATGATGAGGCACGagggaattaaaaatttcgtatgCCCCGAGTGTGGCATGAGAAAGACTACAATGCATGAACTGAAAATTCATATGAATTATCATACCCGCGAAAAGCTATATCCATGCAAAGAGTGTTCGTCAGTATTTTCGAGCCCGGGTAATCGTGGTCGTCACTTTAAAATTGTTCACTGTGGCATTAAAGCGTATCAGTGTTTGCATTGTGAACGATCATTTGGTAAGGCTGAGACACTTAAACACCATGTGATGACACATACTGGGGAGAGGCCACACATATGCACGATGTGCGGTAAACGATTTATTCAGCTCGTCGCTTTACAAACTCATATGAAAACTCATAGTAAAtgtgtttaa
- Protein Sequence
- MTDEQNASETAEGTPQEKSAKQLEKEAKKAAKLEKLQQKLDKKTTEQQKNTGKEKVEKKVKEIKETIVYTGNTAAGEKKDISGSIPDAYSPQYVEAAWYSWWEKQGFFKPEYGRKSILDENPKGKFVMVIPPPNVTGSLHLGHALTNAIEDALTRWHRMKGCTTLWVPGCDHAGIATQVVVEKKLWREQKLTRHDLGREKFIENVWNWKREKGDRIYEQLKRIGSSCDFERANFTMDPKLCNAVNEAFVRLYEDGSIYRSSRLVNWSCTLRSAISDIEVDKVELPGRTFLSIPGYPNKIEFGVLISFAYKVEDTDEELIVATTRVETMLGDTAVAVHPNDARYKHLHGKFVVHPFTDRRIPIVIDDFVEMEFGTGAVKITPAHDPNDYEVGKRHNLPFITIFDDDGIIIGDYGEFTGMKRFDCRVAILKALKDRDLYRETKDNPMVVPVCSRSKDVVEPLIKPQWYVKCDDMAKAATEAVQSGELKIIPDTYEKIWYHWMNGIRDWCVSRQLWWGHRIPAYLVRFNDESKTPKNLSEDAFWVVGRNVEEALKKAANKFNIAKSEITLKQDDDVLDTWFSSGLFPFSVFGWPENTDELKAFYPTTLLETGNDIIFFWVARMVFFGQKLLGKLPFKEVFLHAMVRDAHGRKMSKSLGNVIDPMDVIMGIALEDLHEQLYESNLDPKEIDKAKAGQKQDYPTGIPECGTDAMRFALCAYMSQGRDINLNIQRVQGYRFFCNKLWNATKFALLYFNDTEKYDPIVKLTGTESNVDLWILSQLAKTIDLCNTGFKQYELAAATTACYNFWLYELCDVYLECLKPVFQAADGDDKKVSARKTLYTCLELGLKLISPFMPFISEELFQRLPRAETKTPSICVAEYPETEKFNWRNEPLEKEFEFVQRIAKIIRSARSDYNLPNKIKTEIYVVCSDPEILSSLEKFNGDLLVLSFCSTLKLNEEPPVGCAILTISDKCVIHVVLKGLIEVDKEISKLEKKQESLNQTIGKLGQAIADPTYATKVPEEIRLQNTEKMTQSEGELERVIAAIATLKTITRGTVYNTEMSLEYPRELEYKHIDLKQCRCCMKSEDYENMRLIYERSNKEIADMYCKYTSIELNRDDGLPQEICTTCLITFIRFHEFCVMCSKSDTVFREQKRLMSNTVKVEETDDESQINVVDVDEEPDPIKIEPIKLESDFELGIINEENERHSEEDDDVDGGVFDQEESVHEDIKDIKPKPTKQISRIFPCSQCDKKFYRERRLEGHLRQHKGLKPAVCTICDKEFSKWTALDTHILYSHNNAERKFICDEPDCDKSYMMKQSLTTHKKRVHSKTPDLKPESTYICELCGKSFATTATLKKHSFIHSGQRPFVCTLCPKKYITNHKLKEHMMRHEGIKNFVCPECGMRKTTMHELKIHMNYHTREKLYPCKECSSVFSSPGNRGRHFKIVHCGIKAYQCLHCERSFGKAETLKHHVMTHTGERPHICTMCGKRFIQLVALQTHMKTHSKCV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -