Basic Information

Insect: Tipula vernalis
Gene Symbol: grau_2
Assembly: GCA_958295665.1
Location: OY282560.1:62663360-62664850[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.45 2.5e+02 5.7 0.1 6 23 217 234 217 234 0.95

2 9 5.1e-07 0.00028 24.4 1.5 1 23 240 262 240 262 0.99

3 9 2.2e-06 0.0012 22.4 2.1 1 23 270 292 270 292 0.98

4 9 1.4e-05 0.0078 19.9 0.2 1 23 300 322 300 322 0.98

5 9 3.3e-07 0.00018 25.0 0.2 1 23 328 351 328 351 0.96

6 9 0.0028 1.5 12.7 2.8 2 23 360 381 359 381 0.97

7 9 0.19 1.1e+02 6.9 3.9 1 17 387 403 387 411 0.79

8 9 4e-06 0.0022 21.6 2.5 1 23 416 438 416 438 0.97

9 9 0.0089 4.9 11.1 5.6 1 21 444 464 444 465 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.45	2.5e+02	5.7	0.1	6	23	217	234	217	234	0.95
2	9	5.1e-07	0.00028	24.4	1.5	1	23	240	262	240	262	0.99
3	9	2.2e-06	0.0012	22.4	2.1	1	23	270	292	270	292	0.98
4	9	1.4e-05	0.0078	19.9	0.2	1	23	300	322	300	322	0.98
5	9	3.3e-07	0.00018	25.0	0.2	1	23	328	351	328	351	0.96
6	9	0.0028	1.5	12.7	2.8	2	23	360	381	359	381	0.97
7	9	0.19	1.1e+02	6.9	3.9	1	17	387	403	387	411	0.79
8	9	4e-06	0.0022	21.6	2.5	1	23	416	438	416	438	0.97
9	9	0.0089	4.9	11.1	5.6	1	21	444	464	444	465	0.95

Sequence Information

Coding Sequence: ATGGATTACGATGTAAAAACCTTATGTCGACTATGTTTAATAAAGCCTGAGTACTCCGAGAATATACTAGCCAATGAAAATCTCAAAGggaaattaagaatatttttcaaaattgatcttCAATCTGCAGATGACATGTCGAGTTTAGTATGCAGTTCTTGCTTTCAAATTATCGATCATTTTGCCAAATTTTGTGACAAGGTAGCCGAAAATCAAGGTATCTTACGGCAAAAGATAGCCGCATCAATTAAAATTGGAAGTCCAAAACCAAAAGACGAGCTTAATGAAGATGATGATGTCGACCGATTAGGAGTGTCAGCTCACAATAGTGCTGTCGAAGATGATTTTGTCGAATCGAAACTTGAGATTTTGCATATCAATGTAGATGCTCGACCCAAATCgagtagaaaacaaaaattgttcgcGAAACGGGATAACGACACAGGGGACAGCGGCTCGGAACCGGACTTGGATAAGGTgataaaaaaacctaaaaagcGTCAAGCTGAAAGCGACTATGACGATAGAATTCGAGAATTTCTGACTCTAGTGTGCGACCAATGTGAAAAATATGAGATTTACGACACATTCAAACAGCTAAGTGATCATTTTAAACGTGTCCACAAAACTCGCGGCTATATAACGTGCTGCGACAAAAAGTTCTACCGCAAAGACATCCTGGTGAGTCACATCACCGGCCACATAAATCCAGAGGCATACAAATGTAAATTGTGCGGCAAAATTAGTAAAAGTAAATCACTGTTACAAACGCACATGAAAGTACATTTACCCGTTGACCAACGTGAGTATGAGTGTCCCACGTGTAATCAACGGTTTGCAACAAAATCACATCTtgccaaacataaaatttctcatTTACCCGATTCAGAAAAGAAATTCTCATGTGAAGAGTGTGGCAAAGCGTTTGGAGTTAAAAACGCCTTAACCCAACACAAACTAACGCATTCATCGgaaagaaatttcgtttgcgaAGATTGCGGCCGCTCATTTGCCGTTAAATCTTATCTACAAAATCACATAAATAATATACACAATAATGAGCCGAAGCCGAAGCTGCAGTGTCACATATGCCAATCGTGGTTTAAAAATAATGACACGCTACGTAAGCACGTACGCCAGCATAACGACCAAACGGAATATAAATGCGAGTATTGTGATAAAATATGTTCGTCGCGTGACGTCTGGTGGTGTCATGTTCGTTTTGTTCACAAAAAGATTCGTCAACATGAGTGTAGTATTTGTGAACGAAAATTTAGACGAAGATACGAGTTGACAGAACACATGGCAAAACATACAGGCCAACCGCTATACAAATGCCAGTACTGTAGCAGACAATTTATGTACAGCTCGCACTTTTCACAGCATCGCAAGAAATGCCAATTGATAGCTCAGGAGCAACAAGTACAGGAGCAACAAGTACAGGAGCAACAAGTACAGGAGCCGATTAATAATTATCAACCAATGGTTTAA
Protein Sequence: MDYDVKTLCRLCLIKPEYSENILANENLKGKLRIFFKIDLQSADDMSSLVCSSCFQIIDHFAKFCDKVAENQGILRQKIAASIKIGSPKPKDELNEDDDVDRLGVSAHNSAVEDDFVESKLEILHINVDARPKSSRKQKLFAKRDNDTGDSGSEPDLDKVIKKPKKRQAESDYDDRIREFLTLVCDQCEKYEIYDTFKQLSDHFKRVHKTRGYITCCDKKFYRKDILVSHITGHINPEAYKCKLCGKISKSKSLLQTHMKVHLPVDQREYECPTCNQRFATKSHLAKHKISHLPDSEKKFSCEECGKAFGVKNALTQHKLTHSSERNFVCEDCGRSFAVKSYLQNHINNIHNNEPKPKLQCHICQSWFKNNDTLRKHVRQHNDQTEYKCEYCDKICSSRDVWWCHVRFVHKKIRQHECSICERKFRRRYELTEHMAKHTGQPLYKCQYCSRQFMYSSHFSQHRKKCQLIAQEQQVQEQQVQEQQVQEPINNYQPMV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01458934;
90% Identity: iTF_01456759;
80% Identity: -