Basic Information

Insect: Tipula vernalis
Gene Symbol: -
Assembly: GCA_958295665.1
Location: OY282560.1:333677851-333679906[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 2.7e-06 0.0015 22.1 4.5 1 23 268 290 268 290 0.97

2 12 2.1e-07 0.00012 25.6 0.3 1 23 296 318 296 318 0.99

3 12 0.00012 0.064 17.0 1.4 1 23 324 346 324 346 0.99

4 12 1.3e-06 0.0007 23.2 0.6 1 23 352 375 352 375 0.96

5 12 0.00035 0.19 15.5 0.8 2 23 384 405 383 405 0.97

6 12 9.5e-06 0.0053 20.4 1.0 1 23 414 436 414 436 0.98

7 12 2.9e-06 0.0016 22.0 3.0 1 23 442 464 442 464 0.98

8 12 4.3e-06 0.0024 21.5 1.4 1 23 470 492 470 492 0.99

9 12 2.8e-05 0.015 19.0 5.5 1 23 500 522 500 522 0.98

10 12 0.00035 0.2 15.5 0.9 1 23 530 553 530 553 0.95

11 12 0.029 16 9.5 0.1 1 23 557 580 557 580 0.95

12 12 0.0012 0.66 13.8 1.7 3 23 587 607 585 607 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	2.7e-06	0.0015	22.1	4.5	1	23	268	290	268	290	0.97
2	12	2.1e-07	0.00012	25.6	0.3	1	23	296	318	296	318	0.99
3	12	0.00012	0.064	17.0	1.4	1	23	324	346	324	346	0.99
4	12	1.3e-06	0.0007	23.2	0.6	1	23	352	375	352	375	0.96
5	12	0.00035	0.19	15.5	0.8	2	23	384	405	383	405	0.97
6	12	9.5e-06	0.0053	20.4	1.0	1	23	414	436	414	436	0.98
7	12	2.9e-06	0.0016	22.0	3.0	1	23	442	464	442	464	0.98
8	12	4.3e-06	0.0024	21.5	1.4	1	23	470	492	470	492	0.99
9	12	2.8e-05	0.015	19.0	5.5	1	23	500	522	500	522	0.98
10	12	0.00035	0.2	15.5	0.9	1	23	530	553	530	553	0.95
11	12	0.029	16	9.5	0.1	1	23	557	580	557	580	0.95
12	12	0.0012	0.66	13.8	1.7	3	23	587	607	585	607	0.96

Sequence Information

Coding Sequence: ATGAgcataaaaattgatataaatgtATGCAGAGTTTGCATGAAAACGGGTGATGGAATATCCATCTATTCGGATAGcgaaatagcaaaaaaatttcaattttgtacacaattagagGTTTCACAACATGATGATTTACCAAAAACATTATGCAATAAATGTATTGGACGATTAAAAATCGCTTACGATTTTCGTAAACAAGCTGAGACGACACACAAACATTTAAGGCAGGTCATAACTCATTTCACAGAACAACTAAACCAGTCCGTACAGGTGAAACAGTGTTTGGACGATGAATTGGATAATGAAATTGACGATATGTTGGCAGAATCACATGATTATGTGGAGGAGCAAATAATGCCAACGGCGAAAATTGAATTGGACCAAGATGATCAAATTAGGCAATTGAACGATCATGACCACCATCAAGATAATGAGTCGGAAGAGCTTCCAATGTTAAACATTTCAGATGAACAGAATACTATTTCGGTTGAAGGGGAGGGCATAGTTTATGAGGAAATAGAACGAGAAGTTGATGAGGGTCCCGTATATATCGAAGTCGAGGAATGCGGCGATGTCACTAGTGAAGCTCATATGGAGGAAGTGGAAGAGATTGAAGAGGGTGATGTTATGGATGATACGGAAATGGAAGATAGGAAAGgattaaatttattcacaataaCGGAAGTTAATTATATTACTGAGAACGAGTGCGATCAAACCGACCCTGGTACCGGAAACGAGAGTGATTCGAAAAAAGATGTGGAATCATTAAGCGACCTCCTCTTTTCAGGCAAAACCCACAACTGCAGTAAATGTAATAAAGACTTTAGTACCAAAACTAATTTGATTCGCCATTTACAAACCCACGATGGCGTTAAACCGTACGAGTGCACCATATGTGGTGCTCGGTTCACACAGAACGGTTCACTCAAGCAGCATTTACGAATCCATTCGGGTGAACGACCTTATAAGTGTAATGTGTGTGGTCGGGGCTTTACTCAGGGTAAATCTTTATCATTCCATATGAGACGGCATACAGGTGAAAAACCTTACACTTGCGAAACGTGTGGCTTATCTTTCCGGCAGAAGGACGGTTTAAAGCGGCATGTCTTGATTAAGCACAGTGATATTGAGGTGGAGGGACAACCGTGTCCAACGTGCGGAAAACTTCTCTTCTCGAAGTACACATTACAAATGCACATGAAAAAGCATGTAGGATCACAGCCAGAAGACACCCACAAATGTGGAAAATGCGAACGAGCTTTCTCGTCGAAGGCTTCACTAATAAATCATGTTCGTTGGCATACTGgagaaaaaccatttaaatgtGACACATGCGGAAAACATTTTTCCCAGAAAGGATCTTTAGTGTCACACTTGAAACAACATTTGGATGTAAAACCATACAAATGCGAAACGTGTGGCAAAGGTTTTACCCAAAAACATCAAATAGTAGCCCATCTGAATATGCATCAAAatcagaatttaaagaaatttaaatgttcaaagTGCCATAAAAGCTTCACTATAAAaagaaaCTTGATCCAACATCTTAAAAACCATGAGCGTGATGATTTAGAAGATTTTAAATGTGAAGACTGCAATATTGGATTTAATTCGAGACGCGGATTAAAATTACATCGTAGCAATCAGCACAAAGACGATCATATTTGTGAAGTATGCAATATACAATTTGATTTGGTTACCGATTTAAATCAGCATATCGAGGTGGAACACGACGAAATTGACATGAATTGCGAGATATGTGATCAACAATTTTTCTCACACAAGCTACTGACGAGCCATATGTTGGAACATGAACTTGgtgaaatgtcataa
Protein Sequence: MSIKIDINVCRVCMKTGDGISIYSDSEIAKKFQFCTQLEVSQHDDLPKTLCNKCIGRLKIAYDFRKQAETTHKHLRQVITHFTEQLNQSVQVKQCLDDELDNEIDDMLAESHDYVEEQIMPTAKIELDQDDQIRQLNDHDHHQDNESEELPMLNISDEQNTISVEGEGIVYEEIEREVDEGPVYIEVEECGDVTSEAHMEEVEEIEEGDVMDDTEMEDRKGLNLFTITEVNYITENECDQTDPGTGNESDSKKDVESLSDLLFSGKTHNCSKCNKDFSTKTNLIRHLQTHDGVKPYECTICGARFTQNGSLKQHLRIHSGERPYKCNVCGRGFTQGKSLSFHMRRHTGEKPYTCETCGLSFRQKDGLKRHVLIKHSDIEVEGQPCPTCGKLLFSKYTLQMHMKKHVGSQPEDTHKCGKCERAFSSKASLINHVRWHTGEKPFKCDTCGKHFSQKGSLVSHLKQHLDVKPYKCETCGKGFTQKHQIVAHLNMHQNQNLKKFKCSKCHKSFTIKRNLIQHLKNHERDDLEDFKCEDCNIGFNSRRGLKLHRSNQHKDDHICEVCNIQFDLVTDLNQHIEVEHDEIDMNCEICDQQFFSHKLLTSHMLEHELGEMS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01052494;
90% Identity: -
80% Identity: -