Tver033607.1
Basic Information
- Insect
- Tipula vernalis
- Gene Symbol
- ZEB2
- Assembly
- GCA_958295665.1
- Location
- OY282558.1:229719659-229733684[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 9.5e-07 0.00053 23.6 2.1 2 23 158 179 157 179 0.98 2 18 3.7e-06 0.0021 21.7 2.1 1 23 185 207 185 207 0.98 3 18 2e-06 0.0011 22.6 0.5 1 23 213 235 213 235 0.98 4 18 0.0046 2.6 12.0 5.2 1 23 241 263 241 263 0.95 5 18 5.6e-05 0.031 18.0 1.2 1 23 269 292 269 292 0.97 6 18 1.2e-08 6.6e-06 29.6 0.2 1 23 298 320 298 320 0.99 7 18 0.39 2.2e+02 5.9 0.4 1 14 326 339 326 342 0.87 8 18 0.39 2.2e+02 5.9 2.4 1 23 564 587 564 587 0.97 9 18 0.0032 1.8 12.5 1.7 1 19 593 611 593 613 0.94 10 18 0.00045 0.25 15.2 0.7 1 23 621 643 621 643 0.98 11 18 0.00029 0.16 15.8 2.4 2 23 650 671 649 671 0.96 12 18 0.0028 1.6 12.6 1.1 3 23 678 699 676 699 0.95 13 18 2.2 1.2e+03 3.6 0.2 3 23 721 741 720 741 0.89 14 18 6.6e-06 0.0037 20.9 1.2 1 23 747 769 747 769 0.98 15 18 1.1e-05 0.0064 20.2 4.0 1 23 788 810 788 810 0.97 16 18 0.00011 0.064 17.0 3.4 1 23 816 839 816 839 0.96 17 18 2.3e-05 0.013 19.2 0.4 2 23 848 869 847 869 0.96 18 18 0.00026 0.14 15.9 6.0 1 23 875 898 875 898 0.96
Sequence Information
- Coding Sequence
- ATGGAAATACATATTACGGATAAATCATGTCGGATATGTTTAAAGAATAACGGGGAGTTACCATTATTTGAAAGCCACAACAATTCTATAATTGCTTGTATGGTTACAGCAGTAATAAACATTAATattcCGAATGATGTAAATTTGCCAAATAGCATTTGTTTAAAATGTATGAACAACATAAATATTGCTGTTAAACTAAAACAAGATGTTATAAACTCAGATTTTATGTTAAAGGAGTACGGAAGAATTGACTTATCCAGCAATGGTATTCCAAATGAAACTTTAAAGTTAGAGGACGAAGCTCACCTGTTTGATTGTGGTCGCAGCAGATCATCAACAAGCAGTGAGGGTGATTCAAAAAGTATTGATGAATACATTCCAGcaaaagaaattcaaagaaaacaaaagatTGTTTCTAGTACAACAAGAAGAAGAAAGAAAATGTTTAGCAGTTTACAGGAGTTTAAGAAATGCGagaaatgtcagaaaaagtTTAAGACAGAAGATAATCTAGCTCAGCATATGCGAATACATTCAGGACACAAACCATTCGAATGTAATCTATGTGGAAAACAATTCACTAAAAAGGGAAGTTATAACATTCATCAAAGAAAACACACGAATGAGAGGCcttatatttgtgaaatatgtaGCAAACAATTTATGTCCAGTGGTAATTTACAGCAACACATGTTAACTCATGAAACCCAACGAAAATTCCATTGCAAAGCTTGCGATAAAACATTTTGTCATGAGAAAGGATTAAAAGCTCATATTGTATTACATTCCGGTGAAAAAAATCACGTTTGCCAAATTTGCGAAAGAGCATTTCCAATTAAAAGTTATTTGACAAGGCACACGAAAACTGTACATTATCAAGAAAAACGTTTTAAGTGTTCCGAATGTGGAAAAGCCTTTTCAAATTCAGGGAATCTTCAAGCTCATGTACGTATACATACTGGAGAAAAACCGTACGAGTGTACTTATTGTGATTCTAAATTTAATCAATCTACGCCATTGGTAATCTGTAATGATAATTTGCCGGATGCTGTATGTTCAAAATGTATGGAAAACATAAATATTgcctttaaaataaaagaagatattattaattcagaaaatatgttaaatacatatttggaaaCGAACAATACAGTTGCAGAACTAACTGAAAATTTCTTTCAGCAAATAAACAATACTGCAGAACTACCTGGAAATTTCCCACATATTAAAGTTGAAGACAAAATCGTAACATCGAAATTGGTTGGTCTAGACATTGAACACCTACAGGAAATAAACAATACAGCTGCAGAACTACCTGGAAATTTCCCACATACTAAAGTTGAAGACAAAATTGTAACATCGAAATTAGTTGCTCTAGACATTGAACACCTTCAGGAAATAAACATTACAGTTGCAGAACTACCTGGAAATTTCCTACAGGAAATAAACAATGAAGCTGCAGAACTATCTGAAAATCTACAGGATATAAACAATACAGCCGCAGAACTACCTGGAAATTTACCACTTATTAATGTTGAAGACAAAATCGTAACATCGAAATTGGTTGGTCTAGACATTGAACATTTATATCTAGACAAAATCGAAGACAGTAAACTAGATTCTGAAGTTGTATACACCAAAACTACAGAAGTGCCAACGACTTCTTTCGAATCTTCCAAAATATATGACTGCGAGAAATGTAATTTCAAAACAGATACCTATAAGCTATTAATTTTTCACATGAGGAGAACTCATCAAGGTATAAACTTGTTTGAGTGTGAACAATGTGGCAAAGAATATAGAACAAGGTCAAAATATAGTGTACATGCATGTCCCAATAGAATTTATAAGCCTTATAAATGTGACAAATGTATGAAGGGATTTAATGGCCGATCAAATCTTGTTCAACACCTCGTAACGCATAACACGGAACGTATAATTCCATGTCCAAATTGCGATAAAAAGTTTTGCCATATGAAAGGACTAAGAGCACATTTATTAaaccataatgaaaaaaatataatatgtgaAGTTTGTGGCAACAAATTTAAACATACCACGTTTCTGAAAATTCATATAGCAACAAAGCATGGAAATGTGTCCGGGAGATCTAACAACGGAGTCACGCTGCCCCAGGAACCAGCCCAAGTGGCTTGCGAATGGTGCGGAAAATTAATATTCCTCAATAGTTTGAGGAGCCATATTAGAAATGTGCATTCAGAGCAAAAGTCATTTAAATGTCCGTTTTGCGATAAAGCATTTTCCACGTCGGGGCGTTTAAACTACCATATACAATATCATGCTAATTCGAAAACCATTTCGTCGGACTCTGAAATCTTGAAccgatatttaaaatataaatgtgataaatgTGACAAAGCGTTTACAAGTTCAtgtaatttgaaaaatcataaaatcctTCATTCTGGGTTGAAAGAGCATGTTTGTCCACATTGTGGTAAAGAATTTGCTTTTAAACATTATGTAGAGAGGCATGTACGCTTAGTTCACGACACAACGAATCCAAGAAATTCTGTATGTTTTGTTTGCGGTAAAGTATATGCGAGTTCTTCGTGTTTAAAAGCTCACATGGTTGTACATACTGGCGAAACACCTTatcattgtaaattttgtgatacTAAATTCAGATATCCAAAATCACTTCGAAGACACATGAGCAACAAACATCAAACAAAAGTTACTAATGTTACGGAGCATATATCAAACAATATAAAGTACTATTCATACCAGACGATtgagctttaa
- Protein Sequence
- MEIHITDKSCRICLKNNGELPLFESHNNSIIACMVTAVININIPNDVNLPNSICLKCMNNINIAVKLKQDVINSDFMLKEYGRIDLSSNGIPNETLKLEDEAHLFDCGRSRSSTSSEGDSKSIDEYIPAKEIQRKQKIVSSTTRRRKKMFSSLQEFKKCEKCQKKFKTEDNLAQHMRIHSGHKPFECNLCGKQFTKKGSYNIHQRKHTNERPYICEICSKQFMSSGNLQQHMLTHETQRKFHCKACDKTFCHEKGLKAHIVLHSGEKNHVCQICERAFPIKSYLTRHTKTVHYQEKRFKCSECGKAFSNSGNLQAHVRIHTGEKPYECTYCDSKFNQSTPLVICNDNLPDAVCSKCMENINIAFKIKEDIINSENMLNTYLETNNTVAELTENFFQQINNTAELPGNFPHIKVEDKIVTSKLVGLDIEHLQEINNTAAELPGNFPHTKVEDKIVTSKLVALDIEHLQEINITVAELPGNFLQEINNEAAELSENLQDINNTAAELPGNLPLINVEDKIVTSKLVGLDIEHLYLDKIEDSKLDSEVVYTKTTEVPTTSFESSKIYDCEKCNFKTDTYKLLIFHMRRTHQGINLFECEQCGKEYRTRSKYSVHACPNRIYKPYKCDKCMKGFNGRSNLVQHLVTHNTERIIPCPNCDKKFCHMKGLRAHLLNHNEKNIICEVCGNKFKHTTFLKIHIATKHGNVSGRSNNGVTLPQEPAQVACEWCGKLIFLNSLRSHIRNVHSEQKSFKCPFCDKAFSTSGRLNYHIQYHANSKTISSDSEILNRYLKYKCDKCDKAFTSSCNLKNHKILHSGLKEHVCPHCGKEFAFKHYVERHVRLVHDTTNPRNSVCFVCGKVYASSSCLKAHMVVHTGETPYHCKFCDTKFRYPKSLRRHMSNKHQTKVTNVTEHISNNIKYYSYQTIEL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -