Basic Information

Insect: Tipula unca
Gene Symbol: -
Assembly: GCA_951394425.1
Location: OX596380.1:9005138-9006384[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 2.9 4.3e+02 3.1 1.9 1 22 151 172 151 174 0.77

2 7 7e-06 0.001 20.8 3.3 1 23 182 204 182 204 0.98

3 7 0.0002 0.029 16.2 0.4 1 23 247 269 247 269 0.97

4 7 4.5e-05 0.0067 18.2 1.3 1 23 275 297 275 297 0.96

5 7 7e-06 0.001 20.8 1.1 1 23 303 325 303 325 0.97

6 7 3.7e-05 0.0055 18.5 1.0 1 23 331 353 331 353 0.97

7 7 0.00016 0.024 16.5 0.8 1 23 359 381 359 381 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	2.9	4.3e+02	3.1	1.9	1	22	151	172	151	174	0.77
2	7	7e-06	0.001	20.8	3.3	1	23	182	204	182	204	0.98
3	7	0.0002	0.029	16.2	0.4	1	23	247	269	247	269	0.97
4	7	4.5e-05	0.0067	18.2	1.3	1	23	275	297	275	297	0.96
5	7	7e-06	0.001	20.8	1.1	1	23	303	325	303	325	0.97
6	7	3.7e-05	0.0055	18.5	1.0	1	23	331	353	331	353	0.97
7	7	0.00016	0.024	16.5	0.8	1	23	359	381	359	381	0.95

Sequence Information

Coding Sequence: atggaaaagtaCTTAAATTACGAAACTTTGTGCCGAATCTGCCTACAAGAAACACTCGACAAAGAAAAAGGTTTATTCGACATACTAATAGATGATGTAAAATATTCCGATGTAATTAAGTTAATCGCTCAAATTGATGTGGACCCCGATGACATCTTACCAAGTCGATTATGTGGGATGTGCGAAGACAGCTTAGTGGATGTGTATAAATTACGAGAGTTGTGCCTAAAAAGTAATGATCTACTGCAAATGCAAGAGaataattcaaatgattttAAGGATTACGATGATATGGAGACTATAAATGGTGATGTAGTGCCAAAGGACGAAATGATGAATGAGGTGGGGGATCCAAACACAGGGCCCAAAGAAGAAGAGCAGAAAATTACTAGTGATGATGACgtgtttatagaaaataatcaaGAAGATATTAAACTTGAGTCTGGGACCCACATGTGCCAAACGTGCAATCAATCATTTTTACTGTTATCGGATTATGAATATCATAATAAAGAGAAACATTCGCCTGCTATTCGGCGTCCACACCAATGTCAGCGGTGTCCTTTGAGATTTTCAAAACGGGAGGATTTGATTAAGCACATGAGGCGACACATGCGACCAAAAAGTGTCAAGGACACTACAAAacgaataataatacaaaaaccgCAGAGAACAACCGGGACTACTGCGGCGATATCAAAATATAGCTACAAGAATATAGATCCACAAGATAAGCCATTTGCGTGTACTACTTGCCCGGGTCGATTTACCACTGAATATTACTTAAAAATTCACGAACGAATTCATACCGGTGTCAAACCGTATGTGTGCCGAATATGTGGCACACAATTTGCTCGATCGACATATCTGCGGCAACACGAGAAATTTCATACGGGTATTCGTAATCATCCGTGCGATTTATGCCCAAAACGGTTTTATTCATCGGGCGATTTACGTGTGCATCGGCGGCTGCACACGGGAGAAAAACCTTTTCCGTGTGAATTCTGTGGCAGCCGGTATCGTCGCAAAGCAGATctgaaaactcatctcaaattaCATATCGGGGAAAATACCTATTTGTGCACGAAATGTGATGCAAAATTCCGGTTTTCCGTTGAGCTCCGAGAACATTTACGTGATCATTTTTTAGCGGAAAAAGAGGCAACTACACAAACATAA
Protein Sequence: MEKYLNYETLCRICLQETLDKEKGLFDILIDDVKYSDVIKLIAQIDVDPDDILPSRLCGMCEDSLVDVYKLRELCLKSNDLLQMQENNSNDFKDYDDMETINGDVVPKDEMMNEVGDPNTGPKEEEQKITSDDDVFIENNQEDIKLESGTHMCQTCNQSFLLLSDYEYHNKEKHSPAIRRPHQCQRCPLRFSKREDLIKHMRRHMRPKSVKDTTKRIIIQKPQRTTGTTAAISKYSYKNIDPQDKPFACTTCPGRFTTEYYLKIHERIHTGVKPYVCRICGTQFARSTYLRQHEKFHTGIRNHPCDLCPKRFYSSGDLRVHRRLHTGEKPFPCEFCGSRYRRKADLKTHLKLHIGENTYLCTKCDAKFRFSVELREHLRDHFLAEKEATTQT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01456828;
90% Identity: -
80% Identity: -