Tunc027987.1
Basic Information
- Insect
- Tipula unca
- Gene Symbol
- -
- Assembly
- GCA_951394425.1
- Location
- OX596381.1:185326282-185330169[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 0.24 35 6.5 1.8 2 23 146 168 145 168 0.96 2 18 0.35 52 6.0 0.3 6 23 177 194 177 194 0.99 3 18 0.13 20 7.3 2.7 1 23 200 223 200 223 0.92 4 18 4.7e-06 0.0007 21.3 2.2 1 23 231 253 231 253 0.98 5 18 0.00064 0.095 14.6 0.7 1 23 261 284 261 284 0.96 6 18 0.015 2.2 10.3 1.4 2 23 291 313 290 313 0.96 7 18 0.57 84 5.3 1.9 2 23 322 343 321 343 0.95 8 18 0.12 18 7.4 4.0 1 23 350 373 350 373 0.93 9 18 9.2 1.4e+03 1.5 1.5 2 23 484 506 483 506 0.88 10 18 1.7 2.6e+02 3.8 1.0 6 23 515 532 515 532 0.98 11 18 0.0062 0.92 11.5 2.3 1 23 538 561 538 561 0.93 12 18 1e-05 0.0015 20.3 1.3 1 23 569 591 569 591 0.97 13 18 0.00059 0.087 14.7 0.3 1 23 596 619 596 619 0.95 14 18 0.017 2.6 10.1 2.0 2 23 626 648 625 648 0.96 15 18 0.033 4.9 9.2 2.3 2 23 655 676 654 676 0.97 16 18 0.48 71 5.6 5.3 1 23 683 706 683 706 0.92 17 18 0.00028 0.042 15.7 2.9 1 23 712 734 712 734 0.98 18 18 1.2e-05 0.0017 20.1 1.5 1 23 740 763 740 763 0.98
Sequence Information
- Coding Sequence
- atgGAAATTGTAGAACTTTGCCGTATTTGCTGCAATAATAATGAATCGTTAATAGATATTTATATCCCGAATAATATTTGTACAATACTTCAAAAGCATCTATGGTTCGAgATTCATCCAACTGATCGTCTTAGGAAGATTTGTAAATCTTGTTGGACAGCTGTAgagaattttaatcaattttacacTGAAGTACATAATTCTTATACAGAATATCATTCAAAATTGGTTAAACGTGAAACTAATAATGAGTTAGAATTATCAATTAATGTCTCTTCTGGGCACTCAGTATCCGACTATGAGGATAACAAAATTAGTGATGACGAAAACATTAACAGTATAGTTAAAGCTGTTAAACAACCAGACAAGAAAAAGATTcatgaaaaaattcaaataggcCAAGAAGATGAGAAACTTCGACAATTTTTCAATCTGAGCTGCGACTTGTGTCCTACTCAGTTTCATGTGTTTCTGGaccttaaaattcattatagaaaaaaacataaaattaaaggaTATATTAAATGCTGTGGTAAAAAACTATCTCGTAGAGGCACGGCCCTAGATCACATGCAACGGCATGAGAATCCAGAAATATTCAAGTGCACAATTTGTAGCAAGTGTATGGCTGATAAGCAAACTTTGTATATCCATAACGTTACAAAGCACGCATCAACttttgaaaaatcattcaaatgccCACATTGCCCAAAAACATTTGCTCGTAATTTTGTATTAAGACAGCATTTGCTATCACATGCCTCCGATATCGATAAGAAATACAGCTGTGATAAATGCGACCTATCATTTATTACAAATAGTATATTACAAACTCATAAACGTGCTACGCACGAAGGCGCGTTGACTACGGTTTGTGAAATTTGTGCAAAATCATTTCGATGTAAACAGAACTATGATCGACACATTGCAACTGAGCATAACGATACCCCATCACCAAAAGTTCAGTGTCATCTGTGTGGTGTTTGGCTTAAACACGATCTTAGTCTCCGGAGGCACATGAAAGCACACGAGGATTCAACAAAGACGCATATTTGTAACATTTGTGGGAAACAGTCACCCACTCGAAGCTCATTACTGTGTCACAAGCGTTATACTCATATTGACCCAGTCGATCTTCTTAGAAAGATTTGTGTGACTTGTTGGACGGCTGTACAAAATTTTGACCAATTTTATACCGAAGCTTATAATTCTTATACAGAGtattattcaaaattggttaaaaGTGAGATTAAGAATGAGTTGGAAATATCAATTAATGGTGATGCCGCTTCAGAGTCGACAGAATCTGACTATGAGAATAATGAAGTTAGTGATGACATTGATAAAAGCAGTGTAAACAAAGCTATTAAACCACCAGACAAGAAAAAGATGCAAGAAAGCAGTCAAACGGCAGACGAAGatgaaaaattacgaaaatttttcTCTTTGAGCTGTGAATTATGTCTGGTGCAGTGTAATGTGTTTTTGGACCTTAAAACGCATTATAGAAAAGAGCATAAAATACAAGGATATATAAAATGTTGTGGTAAAAAATTATCTCGTCGGGGTATGGCACTAGATCACATGCATCGACATGAGGATCCGGAGAAATTTAAGTGTTCAATTTGTAACAAGTGTATGGCTGATAAGAAAAATCTGTATATCCATAACGTTACAATGCACGCatcaacttttcaaaaatcatttatatgTCCACATTGCCCTAAAACATTTGCTAGGAATTTTGTATTGAGACAACATTTGCTCTCACATGCCGATAAGAAATACGCATGTGATCAATGCGAGTTATCATTTATTACAAACAGTGTATTACAAACTCATAAACGTGCTTCACACGAAGGCGCTTTAACAACggtatgtgaaatttgtgcAAAATCATTTCGATGTAAACAGAACTATGACAGACACATTTCGACCGAACATACGCCACAACCAAAAGTTCAGTGTCATCTATGTGGCATTTGGCTTAAACACGAATTTAGTCTTCGGAGACACATGAAAGCACACGAAGATTCAACAAAAACTCATATTTGCAACATATGTGGGAAAAAGTCCCCGAGTCGCCACTCATTGCTGTGTCATAAACGATATGCTCATGTCCTGGAAAAAACCCATAAATGTTTGTATTgtgaaaaagcttttaaaatgcgTAAGGAATTAAGGGAACACACGGCCACACATACTGGAGAAGTTCTATACACGTGCCCATATTGCCCGAAAACGTTTAATTCATCGGCCAACAGATCATCACATAAAAGAAAAGTTCACCCGCaaagttaa
- Protein Sequence
- MEIVELCRICCNNNESLIDIYIPNNICTILQKHLWFEIHPTDRLRKICKSCWTAVENFNQFYTEVHNSYTEYHSKLVKRETNNELELSINVSSGHSVSDYEDNKISDDENINSIVKAVKQPDKKKIHEKIQIGQEDEKLRQFFNLSCDLCPTQFHVFLDLKIHYRKKHKIKGYIKCCGKKLSRRGTALDHMQRHENPEIFKCTICSKCMADKQTLYIHNVTKHASTFEKSFKCPHCPKTFARNFVLRQHLLSHASDIDKKYSCDKCDLSFITNSILQTHKRATHEGALTTVCEICAKSFRCKQNYDRHIATEHNDTPSPKVQCHLCGVWLKHDLSLRRHMKAHEDSTKTHICNICGKQSPTRSSLLCHKRYTHIDPVDLLRKICVTCWTAVQNFDQFYTEAYNSYTEYYSKLVKSEIKNELEISINGDAASESTESDYENNEVSDDIDKSSVNKAIKPPDKKKMQESSQTADEDEKLRKFFSLSCELCLVQCNVFLDLKTHYRKEHKIQGYIKCCGKKLSRRGMALDHMHRHEDPEKFKCSICNKCMADKKNLYIHNVTMHASTFQKSFICPHCPKTFARNFVLRQHLLSHADKKYACDQCELSFITNSVLQTHKRASHEGALTTVCEICAKSFRCKQNYDRHISTEHTPQPKVQCHLCGIWLKHEFSLRRHMKAHEDSTKTHICNICGKKSPSRHSLLCHKRYAHVLEKTHKCLYCEKAFKMRKELREHTATHTGEVLYTCPYCPKTFNSSANRSSHKRKVHPQS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -