Basic Information

Insect: Tipula unca
Gene Symbol: -
Assembly: GCA_951394425.1
Location: OX596382.1:86518678-86520293[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 5.2 7.7e+02 2.3 0.6 3 23 217 238 216 238 0.95

2 10 2 3e+02 3.6 0.3 6 23 247 264 247 264 0.97

3 10 7.1e-05 0.011 17.6 2.8 1 23 270 292 270 292 0.99

4 10 1.8e-05 0.0027 19.5 1.4 1 23 300 322 300 322 0.99

5 10 2.3e-06 0.00034 22.3 0.6 1 23 328 351 328 351 0.97

6 10 0.0021 0.31 13.0 2.5 1 23 357 380 357 380 0.96

7 10 0.0081 1.2 11.1 1.4 2 23 389 410 388 410 0.97

8 10 1.9e-05 0.0028 19.4 0.0 1 23 417 440 417 440 0.97

9 10 1.2e-06 0.00018 23.2 0.8 1 23 445 467 445 467 0.98

10 10 3.5e-06 0.00052 21.7 1.8 1 23 473 496 473 496 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	5.2	7.7e+02	2.3	0.6	3	23	217	238	216	238	0.95
2	10	2	3e+02	3.6	0.3	6	23	247	264	247	264	0.97
3	10	7.1e-05	0.011	17.6	2.8	1	23	270	292	270	292	0.99
4	10	1.8e-05	0.0027	19.5	1.4	1	23	300	322	300	322	0.99
5	10	2.3e-06	0.00034	22.3	0.6	1	23	328	351	328	351	0.97
6	10	0.0021	0.31	13.0	2.5	1	23	357	380	357	380	0.96
7	10	0.0081	1.2	11.1	1.4	2	23	389	410	388	410	0.97
8	10	1.9e-05	0.0028	19.4	0.0	1	23	417	440	417	440	0.97
9	10	1.2e-06	0.00018	23.2	0.8	1	23	445	467	445	467	0.98
10	10	3.5e-06	0.00052	21.7	1.8	1	23	473	496	473	496	0.97

Sequence Information

Coding Sequence: ATGAATCTACCACAATGTCGTCTCTGTTTATCAGaatcacaaaattttctgaatgtatttattgaaaaaattgttgataaaacAATTGCGTCCATATTAACTCAACATTTTTGGTTTGAAgtGAAGGAGGATGATTCGAGTAAAGATATTTGCCAGGATTGTTGGATCAAAGTGGAAGATTTCCATATATTTTACTCGAAAGTTTACAATATCCACTGTGAGCTGCTTCCGAAAGTGGATCAAGATATTAAACTGGAAATAGATGATACCCTTAACACGGATAAAATAGAATTGATGATTGATTTAAAACAGATTTCGAATGTCAAAACTGAACACAAAACAAACATAGTAAATAATCAATTTGGCGGCAAACACGATGCATTACTATCTGACTTGGACGATGACGATAAATGGTCACATCACAGTTCTAAGGATACCAATGACCTAAACTATAGTGACAATGAAAGTAACACTGATGAATCTGTTTTTCCGACACCCACACGACGAATATctaaacaaatgtcaaataaaaaagtaaGGAAAACTAAGAAAGTGAAAACAATTCGAACGAAAAAAGAAACAGATCCTGTTGAACAAGCAAAATTAGATCAACAAAATAAGCAAATATCGGAATATTTTTCCATGGATTGTGAGCTGTGTTCACTGAAATTAGATTCAtttcgaaatttacaatttcactataggattgaacataaaattaaaggATACGTAAGATGTTGTAATCGGAAGTATGTAAAACGTGTCTACATACTTGAACATTTGCGGCGCCATTTAAATCCGGAAACATTCAGATGTGAAATATGTAATAAGAATTTTGCAGCGAAACGATGTTTACAGCTTCATTTGCGTAGTCATATACCGACAGAGGAGCGACCGTATAAATGTACTAAGTGTCCTAAAACATATGTTATTCGGAATTTGCTGAAACGGCATTTGGAAACGCATGCAACCGAACGAAAATTTGTATGCGTTGAATGTGGTAAATCATACGTAACAGAATTTCAACTTAAATCTCACCAGCGGAGTATGCATAGTGAGGCCAATATTCATATTTGTGATGTGTGTGCAAAGCCTTTCCGGAGTAAAGATGTTTTTGAAAAGCATCATAAATCTGTACATGGAAAGATTCCACTTCCGAAAGTACAATGTAAAATATGCGGTTCATGggtaaaacataaatattatctcAAGCAACATATGGCACGGCATACAGATAATAATACAAGTTTTCCTTGTAATATTTGTGGAAAATCTGCGCCAAATGTTCGTGCACTTCAAAGCCACATGCGTGTTGTGCATActgaaaaaatgtttgaatgtaATTTGTGTGAAAAAACATTTAAGAGATCGATAAGCTTAAGGGAACATATGGCATCTCATACAGGAGATATTTTGTATTCTTGTCCTTACTGCCCAAAGACGTTTAATTCATCGGCTAACATGTACACACATAGAAAAAAAAGTCATGTAAAAGAATGGGAAGAACAGAAATTAGAGAAACTGAAAGGAGCTGCAACAACATAA
Protein Sequence: MNLPQCRLCLSESQNFLNVFIEKIVDKTIASILTQHFWFEVKEDDSSKDICQDCWIKVEDFHIFYSKVYNIHCELLPKVDQDIKLEIDDTLNTDKIELMIDLKQISNVKTEHKTNIVNNQFGGKHDALLSDLDDDDKWSHHSSKDTNDLNYSDNESNTDESVFPTPTRRISKQMSNKKVRKTKKVKTIRTKKETDPVEQAKLDQQNKQISEYFSMDCELCSLKLDSFRNLQFHYRIEHKIKGYVRCCNRKYVKRVYILEHLRRHLNPETFRCEICNKNFAAKRCLQLHLRSHIPTEERPYKCTKCPKTYVIRNLLKRHLETHATERKFVCVECGKSYVTEFQLKSHQRSMHSEANIHICDVCAKPFRSKDVFEKHHKSVHGKIPLPKVQCKICGSWVKHKYYLKQHMARHTDNNTSFPCNICGKSAPNVRALQSHMRVVHTEKMFECNLCEKTFKRSISLREHMASHTGDILYSCPYCPKTFNSSANMYTHRKKSHVKEWEEQKLEKLKGAATT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01460576;
90% Identity: -
80% Identity: -