Basic Information

Insect: Tipula unca
Gene Symbol: ken
Assembly: GCA_951394425.1
Location: OX596381.1:156000611-156001700[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.00037 0.055 15.3 3.7 2 23 120 141 119 141 0.97

2 7 4.7e-05 0.007 18.2 2.3 1 23 147 169 147 169 0.99

3 7 2.8e-07 4.2e-05 25.2 0.4 1 23 175 197 175 197 0.98

4 7 9.2e-05 0.014 17.3 1.6 1 23 203 225 203 225 0.98

5 7 3.1e-07 4.6e-05 25.0 1.7 1 23 231 254 231 254 0.97

6 7 4e-09 5.9e-07 31.0 0.4 1 23 260 282 260 282 0.97

7 7 0.00017 0.026 16.4 1.0 1 23 288 310 288 310 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.00037	0.055	15.3	3.7	2	23	120	141	119	141	0.97
2	7	4.7e-05	0.007	18.2	2.3	1	23	147	169	147	169	0.99
3	7	2.8e-07	4.2e-05	25.2	0.4	1	23	175	197	175	197	0.98
4	7	9.2e-05	0.014	17.3	1.6	1	23	203	225	203	225	0.98
5	7	3.1e-07	4.6e-05	25.0	1.7	1	23	231	254	231	254	0.97
6	7	4e-09	5.9e-07	31.0	0.4	1	23	260	282	260	282	0.97
7	7	0.00017	0.026	16.4	1.0	1	23	288	310	288	310	0.98

Sequence Information

Coding Sequence: ATGTCGAATGTAAatattgcaataaaattaaaattagatgtaGTCAAttccgaaattaaaattaaagaatactTTGGTAATGAACCAGAAGAGAATgaacaaattgtaaatatatgtttGCTGGAAAATGAATCATTGGACGCTGACATAAAATCTGAAGAAGATTccgaagatgatgatgatgatgaagaaaatGTTTTAGACGATGATTGTAGTTTCGAACCAAATGATGAAGATTCTTTAAGTAACGATGTTATGCCGGAACAGCCAAAGGTAAAACGAAAGAGGAGAAATGGCACCAAAGAACGAAGTGGTAAAAAGAAACGAATTAGAAAAGTGTATACAAGTAAAGAAACCAAGTGTAAAGAATGTGGAAAAGAATTTAATTGCCATGCCAATTTAGTGAATCATCTGAGAATACATACTGGCGAAAAACCTTATGAATGCGATATATGCTTTCAAAAATACTCGCAGCATGCAAATTTGATTGTGCATAAACGGAAGCACACACAAGAAAAACCGTATGTCTGTGAAATATGTAGTAAACAATTTTCCCAAGCTGGTAATCTAAATCAACACCGATTGACGCATCGTACTGAACGAAATTATAAATGTGACATGtgtgaaaaatcatttttacatTCAAAGGCCTTGAAAGCACATATATCGTTGCATTCTGAGGAGAAGAAACATGTGTGCAAGGATTGCGGTAAATCATTTCCattgaaaaactatttaacaCGGCACGTTCGAACGGTGCACTTCCAAGAGAAAAATCATGTATGCAGTGAATGCGGTAAAGCATTTTCTAATTCAGGAAATCTCAAAGCTCATATTCGAATCCATACAGGGGAAAAACCTTTCGAATGTATGTATTGTGATTCGAAATTCAATCAGTCAACTCCATTGGTACGTCACATGcagcaacataaaaaaaataaagataaaataaaagagCCTAGTGACGATGGAAAATCATTCGacttatcgTATCTAACGATGAAGTTTATTCAACATTAG
Protein Sequence: MSNVNIAIKLKLDVVNSEIKIKEYFGNEPEENEQIVNICLLENESLDADIKSEEDSEDDDDDEENVLDDDCSFEPNDEDSLSNDVMPEQPKVKRKRRNGTKERSGKKKRIRKVYTSKETKCKECGKEFNCHANLVNHLRIHTGEKPYECDICFQKYSQHANLIVHKRKHTQEKPYVCEICSKQFSQAGNLNQHRLTHRTERNYKCDMCEKSFLHSKALKAHISLHSEEKKHVCKDCGKSFPLKNYLTRHVRTVHFQEKNHVCSECGKAFSNSGNLKAHIRIHTGEKPFECMYCDSKFNQSTPLVRHMQQHKKNKDKIKEPSDDGKSFDLSYLTMKFIQH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01456723;
90% Identity: iTF_01460543; iTF_01456723;
80% Identity: -