Tunc030184.1
Basic Information
- Insect
- Tipula unca
- Gene Symbol
- -
- Assembly
- GCA_951394425.1
- Location
- OX596381.1:220452524-220453915[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00031 0.046 15.6 1.8 1 23 100 122 100 122 0.98 2 12 0.015 2.3 10.3 0.0 2 23 129 150 128 150 0.97 3 12 0.01 1.6 10.8 2.3 1 23 156 179 156 180 0.97 4 12 0.0049 0.72 11.8 3.1 1 23 185 207 185 207 0.93 5 12 0.032 4.7 9.3 5.9 3 19 215 231 213 237 0.94 6 12 0.0068 1 11.4 0.5 2 23 242 264 242 264 0.95 7 12 0.042 6.2 8.9 0.3 3 23 299 319 298 319 0.95 8 12 1.1e-07 1.7e-05 26.4 1.2 1 23 323 345 323 345 0.98 9 12 0.00065 0.096 14.6 6.6 1 23 351 373 351 373 0.98 10 12 5e-08 7.4e-06 27.5 1.6 1 23 379 401 379 401 0.98 11 12 6e-06 0.00089 21.0 0.7 1 23 407 429 407 429 0.98 12 12 4.7e-07 6.9e-05 24.5 1.4 1 23 435 457 435 457 0.98
Sequence Information
- Coding Sequence
- ATGTCTACAACGCCATGCGGATCCACGGATATTAATAAGCCTAGAGTACGATTTGCCGATAATGTAAAAAGAGAAGACGGTGTAATTACTTGGGTGAAACATGAAGGCCACACTTTAGCTCCGGTCGCGGCCAACAGTAAGGACGATTCAGATTCGGAAGAAACATCCAGTAGTGAAAGTTCATCGGAAACGTCATCATCTTCTTCGTCGGAGGATGATGGAACTATCATTGATACAGTAGTTGATGCTAATAATCCACCATTGGCACAGATCTCAATACCTGCATTAACCGCTTCTTATAGCTgtttattttgtgaaaaaaaatacaGCGTACGCGACCGATTACGAAAGCATATAAAGATTCACGTAAAGACGATGAATTTGGTTTGTCCAATCTGCCAAGAATTGTTCGAAGAAAACTCGATTCTACGGGATCATTTAATGACACATTTTGTAGATAAACCGTATCGGTGCAATTACTGTTTTAATGCTTATCGTATTAAATCTCGTCTAGAAAGCCATATATTGAGAGCTCACCATGCgtctaaaaaatttttatgtgaTCAATGCAATTGTACGTTTAAGCGCCAGGCAAAATTGGATGCACACAAGAGTCTACATGCTCGACATATTCAATTATTCTGTCCAACTTGTGGTAAACACTGCACGACCGAGGAAAGCCTAACAAAACATTGTGCCAAATATTCACATCATGTATTGGAACGATGTGTCCAGTGTTCTGAAATGTTTTCAAATCGAATGGCTTTAgaagatcataaatttacaGTGCACGGTATATGCCACAGTAATTATTATACTGTTTCTGCTCTGCCTCCTGTAAATGTGACGACACAGCAAGTTTATGTCTACGACCAAATTATAGAGAAGAAATTATGTAAACTATGTGGAAAACGATTTCTTACAGCCGCTGCCGCTAAACGGCACGTTTTTAGCCACAACCGCCCCTACATGTGCAAAATGTGTAACAAATCATTTACTCAAGTTAGTTCACTAAATGTCCATATGAAAATTCATTCGGATCGAAAACCACATAAATGTGAATTTTGCGGCAAAGAGTTTCATCTGTTTGATCATTTAACACGACACGTTAGGGTGCACACCAAGGAGAAACCGTTTAATTGTGAAACATGCGGCAAAACATTTACGCAACAAAATTCTCTAACTCTCCACATTCGAACACATACAGGAGAAAAACCGTTTATTTGTGATATATGTGCTAAGGCATTTGTAGTACGGGATCACCTCACGAAACACTATCGAATTCACACGGGTGAAAAACCATATGAATGCGATTACTGTAAAAAGAAATTTACCCAATCGCAAGCGCTAAAGAAACATATTGATGTTcacaagaaatataataaaatttag
- Protein Sequence
- MSTTPCGSTDINKPRVRFADNVKREDGVITWVKHEGHTLAPVAANSKDDSDSEETSSSESSSETSSSSSSEDDGTIIDTVVDANNPPLAQISIPALTASYSCLFCEKKYSVRDRLRKHIKIHVKTMNLVCPICQELFEENSILRDHLMTHFVDKPYRCNYCFNAYRIKSRLESHILRAHHASKKFLCDQCNCTFKRQAKLDAHKSLHARHIQLFCPTCGKHCTTEESLTKHCAKYSHHVLERCVQCSEMFSNRMALEDHKFTVHGICHSNYYTVSALPPVNVTTQQVYVYDQIIEKKLCKLCGKRFLTAAAAKRHVFSHNRPYMCKMCNKSFTQVSSLNVHMKIHSDRKPHKCEFCGKEFHLFDHLTRHVRVHTKEKPFNCETCGKTFTQQNSLTLHIRTHTGEKPFICDICAKAFVVRDHLTKHYRIHTGEKPYECDYCKKKFTQSQALKKHIDVHKKYNKI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01053702;
- 90% Identity
- iTF_01457794;
- 80% Identity
- -