Basic Information

Insect: Tipula unca
Gene Symbol: -
Assembly: GCA_951394425.1
Location: OX596381.1:8123201-8127546[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00017 0.025 16.4 0.8 1 23 155 177 155 177 0.95

2 15 0.0015 0.22 13.5 2.2 1 23 183 205 183 205 0.97

3 15 7.2e-05 0.011 17.6 0.3 1 23 311 333 311 333 0.98

4 15 0.00085 0.13 14.2 0.0 1 23 339 362 339 362 0.97

5 15 0.0014 0.2 13.6 4.1 1 23 393 415 393 415 0.96

6 15 0.0056 0.83 11.6 0.2 1 23 429 451 429 451 0.94

7 15 5 7.4e+02 2.4 0.1 2 23 458 480 457 480 0.71

8 15 0.52 78 5.4 3.5 1 19 487 505 487 506 0.96

9 15 0.00039 0.058 15.3 5.8 1 23 515 537 515 537 0.96

10 15 0.0041 0.6 12.1 0.4 2 23 543 564 542 564 0.97

11 15 1.3e-05 0.0019 20.0 0.4 1 23 572 594 572 594 0.98

12 15 0.0012 0.18 13.7 0.1 3 23 602 622 600 622 0.97

13 15 2.9e-05 0.0044 18.8 0.5 1 23 628 650 628 651 0.96

14 15 0.006 0.88 11.6 0.6 1 23 665 687 665 687 0.97

15 15 0.00025 0.037 15.9 0.1 1 23 1138 1161 1138 1161 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00017	0.025	16.4	0.8	1	23	155	177	155	177	0.95
2	15	0.0015	0.22	13.5	2.2	1	23	183	205	183	205	0.97
3	15	7.2e-05	0.011	17.6	0.3	1	23	311	333	311	333	0.98
4	15	0.00085	0.13	14.2	0.0	1	23	339	362	339	362	0.97
5	15	0.0014	0.2	13.6	4.1	1	23	393	415	393	415	0.96
6	15	0.0056	0.83	11.6	0.2	1	23	429	451	429	451	0.94
7	15	5	7.4e+02	2.4	0.1	2	23	458	480	457	480	0.71
8	15	0.52	78	5.4	3.5	1	19	487	505	487	506	0.96
9	15	0.00039	0.058	15.3	5.8	1	23	515	537	515	537	0.96
10	15	0.0041	0.6	12.1	0.4	2	23	543	564	542	564	0.97
11	15	1.3e-05	0.0019	20.0	0.4	1	23	572	594	572	594	0.98
12	15	0.0012	0.18	13.7	0.1	3	23	602	622	600	622	0.97
13	15	2.9e-05	0.0044	18.8	0.5	1	23	628	650	628	651	0.96
14	15	0.006	0.88	11.6	0.6	1	23	665	687	665	687	0.97
15	15	0.00025	0.037	15.9	0.1	1	23	1138	1161	1138	1161	0.93

Sequence Information

Coding Sequence: ATGGGTGAGGTACCACGGACTCTCCGAATTGACTGGGATATCGACGATGATATTCAGCAGGAGATTATCACCGAGGAGGTGATAGAGTTGAATAATGCCGAAGAAGATGATGAGTATTTGGTTGGCGAGGAAATTATTCCGTCTACCGATGTGACAAATAGTTTGGATCATATAGCGGCCGAGAATTTGATTTATATGGCACATGATGGACATGTACAGAGTATGGGCGATTTAATAGCAGAGCAGGTGGAACAAGTTGAAAATGCGGATTACAATGAGcaacaatattttgaatgtcAAGTCACAGAAGAGGTGATAACCGATGATTGGGTACAACAACAGGGTGAGGAACGAGTTGAAATACCAGTCGATCAATTGTGTACGAGCGGTGAGGTGGTGAATGACGAAGATATGGATGTACCGTTGCCCACGGATCAAGATGAGTATACAACATCTAGACCGTATCCGTGTGATTTTTGCAGTCGGCGTTTTCGTAAAAAAGCAACGCTTATGAATCATATGGTGGCGCATCAAAATGATCGACCTCATGTATGTAACTTATGTGGGGCTCGATACATACGACGTTGTGATTTAttgaatcatttgaaaattcatgcTTATGTGCCAGAAGGTGGGGACTTGGAAGAGTTAGAAAAAATACAAAAAGAAACTACTGTTAAATTAAAACGGAAATACGAATCAAAACGTTATAAATCGGAAAATCgtttttcaccaaaaaaactaaaaatagagCAGCAGTCCGAAGAAGCCGCAACAGTAAAATATGAGTATGTGCAGGACATAAAACTTCTAACATCGGATGATAATGACGGGGATCAGGATGGTGTGGTTGAATCACCAAACGATGATAGTTATGAAGAAGTACAGGACTCGTATATTCGATATCCGGTTACGGATCCAAAGAAACCTTTCGTTTGTCAGCATTGTGGTGTGGGGTTTGCCCGTCAAAAAGCTTTAGCGTCTCATTCAAGGaTACATGGCGGAGACTCGCCATTCGAGTGTGAAACATGCGGTGAAATGTTTTGGGATCCGGCCGCATTACGGGATCATCAACGGTTACAACATCAAGGCCAGGGCGCGGAGTCAGAATACGAAccagaaaatgaagaaaacGAGGAAGATGCATCAGAATCTGAAGACTCAGCATTTGGTGGTTTCTTTTGTGAAACTTGTGGAATGTCATTCCACCGATACGAATTACTAAAACGCCATTCAAGGCAGCATATTAAAAAAGAATCGACCGAGGGTGATTTGGTTGGTGGCCATTGTTGCAATGTATGCGGTGAATCATTTGCCGAAGCATTAGACTTGTTAGCCCATGCTGAGGTGCATGCACGGTGCCAACCattaaaatgtatgttatgTGGTGAATCATTTCTCGAAGAATCCATTATTAAATCTCATATACGTATCGTACATGCAAATGAATTAACCCAGCATTCGTGCCGCCTGTGTGGTAAATTATGTCGTGATAGTCGAACCCTATCGAAACATTCATGGGAACATTCCAGCGAGAAAAATCATTCCTGTTCGAAATGTGGTAAGAATTTCCACAATAAAGCGCGTCTAAAACGGCATATGGTTTCACATCGAAATAAAACGGTTACGTGTGATATGTGCGGTGAAGAATTTCCTGATGGACGCTCCCTCATGAATCATCGTCATTCACATACGAATGTCACAGGGCGACAATTTCCCTGTCGCGAGTGCGGCAAAACATTTGGTTCGCGTAGTTCACAACAAATTCATATACGTATTCATACGGGTGAACGACCATACGGGTGTCGATATTGTTGGAAAGCTTTTGCCGATGGTGGAACGTTACGGAAACATGAACGGATACATACAGGTGAAAAGCCATATGTATGTTCAGTGTGCCCCCGAGCCTTTAATCAGAGAGTTGTGTTACGTGAACATATACGGTCGCATCATTCGAGCCCAGATACCAAGCGGGGCAATGCAGCTACACCGTATTATTGCCAAGTATGTCATGAGTTGTTTGTGACGTCGCTCGACTTAATTCAACATTTGATTCAACACAGTGACATGAATACCGCCATGAAGAGACAACCGATTacggGGCCACGAAAATATAAACGcagaaggaaattaaaaccgCATGAATTGGAAAAATTACGTGCCGAAAAACATGCAGGAAAATTGGGTGAACACGACTACACCGATGATGATGAGCAGTATTTGCAAGATGAAGATGATAATTTCCAGGAAGAGATTATTACGTATAATAAGACAACTCGAACTCGAAATAATACGAGCTCAAATGTAATTCAATCATCACCACCACCGGTATCATCGTATACGACCACAGCACCAGCAATGGAAAATAAGAAGTCGAATAAGAAAAAGAACAACAATAACATTGATGATGTGGATacgttaattaataatttgggtgCGCCGATGGAACTAAATACTGCCCCGACCATAGCGACGGCCACATCCGTAGTCGCAAATAATGCTAAGGCGaccaaatcaatcaataaaaagaaaaaatcggaTGATAACCATCCATCACGACCAAAAAtgatacatacacaaaaaactCGTGTACCAATTGAAGACGGTCGACGAAAAACCAAAACTCTAGTTACATGGACCACACAATCGAGTGAAACGCATGGTGGTGCTAATACCAATGCGAAAAATGAACGAAATCGTCCACGCACCAAAAATGTAAACTATCACATTTTAGTACCTGATAAATTACCAAATGCTACATTTTCAAATGAGCTGAACGATATCATATCGATAAAAAATGAAGATCCAGATAATAAAACGAGTAGTTTTACGCTGCGATACGATAAGGATATACTCGAAAATGATATAAATAGTTTTGGTAATTTAGGGAACCATCTGTTTGAATTGCCACGCAATAGTTTGACCAAATATAATAGTGACATAGTAAATGATTTAGAAGAGATTTTGCGATCCCCGATTAAAGGCCAAACCATGAATCAATCATCGATGAATATATCACCGGGTGATGATGGAACAACATCAGATGAAGCTAGTGAATACCACAATCAAATGGTGGTGAATAGTAGTGTAAACTATAGTACGGCTAGTGGTCGCCCAAGGCGTAATGTAAAacgtaaattttcatttaaaattgaatcaccACCGCATCCAACACCTTCGTCGTCATCATCTGCGCggcaaaatagaaaaatcacgaatactaaaaaaaatgtaaataatagtaGTACTAGTAATTACAGTAGTAGTAATGGTAAGAAAACTAAATCATCAAATAAACGTAATAACAgcagtaataacaataataataatttaaaaatgaaagcgGTAAAAGTGGATTATTCAGATGTCATGATTAAATCAGAAAACGAGCTAATCATACCGGACAATTTATACAAATGTGATATGTGTTCAGCTGTATTTTCTGATCGGTCCCAACTATTGATACACGGGGCATCTATGCACATATGA
Protein Sequence: MGEVPRTLRIDWDIDDDIQQEIITEEVIELNNAEEDDEYLVGEEIIPSTDVTNSLDHIAAENLIYMAHDGHVQSMGDLIAEQVEQVENADYNEQQYFECQVTEEVITDDWVQQQGEERVEIPVDQLCTSGEVVNDEDMDVPLPTDQDEYTTSRPYPCDFCSRRFRKKATLMNHMVAHQNDRPHVCNLCGARYIRRCDLLNHLKIHAYVPEGGDLEELEKIQKETTVKLKRKYESKRYKSENRFSPKKLKIEQQSEEAATVKYEYVQDIKLLTSDDNDGDQDGVVESPNDDSYEEVQDSYIRYPVTDPKKPFVCQHCGVGFARQKALASHSRIHGGDSPFECETCGEMFWDPAALRDHQRLQHQGQGAESEYEPENEENEEDASESEDSAFGGFFCETCGMSFHRYELLKRHSRQHIKKESTEGDLVGGHCCNVCGESFAEALDLLAHAEVHARCQPLKCMLCGESFLEESIIKSHIRIVHANELTQHSCRLCGKLCRDSRTLSKHSWEHSSEKNHSCSKCGKNFHNKARLKRHMVSHRNKTVTCDMCGEEFPDGRSLMNHRHSHTNVTGRQFPCRECGKTFGSRSSQQIHIRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYVCSVCPRAFNQRVVLREHIRSHHSSPDTKRGNAATPYYCQVCHELFVTSLDLIQHLIQHSDMNTAMKRQPITGPRKYKRRRKLKPHELEKLRAEKHAGKLGEHDYTDDDEQYLQDEDDNFQEEIITYNKTTRTRNNTSSNVIQSSPPPVSSYTTTAPAMENKKSNKKKNNNNIDDVDTLINNLGAPMELNTAPTIATATSVVANNAKATKSINKKKKSDDNHPSRPKMIHTQKTRVPIEDGRRKTKTLVTWTTQSSETHGGANTNAKNERNRPRTKNVNYHILVPDKLPNATFSNELNDIISIKNEDPDNKTSSFTLRYDKDILENDINSFGNLGNHLFELPRNSLTKYNSDIVNDLEEILRSPIKGQTMNQSSMNISPGDDGTTSDEASEYHNQMVVNSSVNYSTASGRPRRNVKRKFSFKIESPPHPTPSSSSSARQNRKITNTKKNVNNSSTSNYSSSNGKKTKSSNKRNNSSNNNNNNLKMKAVKVDYSDVMIKSENELIIPDNLYKCDMCSAVFSDRSQLLIHGASMHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01052518;
90% Identity: iTF_01456683;
80% Identity: -