Basic Information

Insect: Tipula unca
Gene Symbol: CBF5
Assembly: GCA_951394425.1
Location: OX596382.1:45790396-45794679[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 1.4e-05 0.002 19.9 4.6 1 23 141 163 141 163 0.98

2 14 0.004 0.6 12.1 0.5 2 23 168 189 167 189 0.95

3 14 0.00084 0.12 14.2 0.9 1 23 194 217 194 217 0.92

4 14 0.0051 0.76 11.8 5.0 1 23 223 245 223 245 0.97

5 14 0.0052 0.78 11.7 3.2 1 21 354 374 354 375 0.96

6 14 0.015 2.2 10.3 4.9 2 23 391 412 390 412 0.95

7 14 0.0002 0.03 16.2 0.1 1 23 418 441 418 441 0.96

8 14 3.9e-05 0.0058 18.4 1.0 3 23 453 473 451 473 0.95

9 14 0.00013 0.019 16.8 2.8 1 23 479 501 479 501 0.98

10 14 3.3e-05 0.005 18.6 0.3 2 23 507 528 506 528 0.97

11 14 7.2e-06 0.0011 20.7 0.3 1 23 533 555 533 555 0.98

12 14 3e-05 0.0045 18.8 0.2 1 23 561 584 561 584 0.97

13 14 0.00035 0.051 15.5 1.0 1 23 590 613 590 613 0.97

14 14 0.00032 0.048 15.5 4.9 1 23 619 642 619 642 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	1.4e-05	0.002	19.9	4.6	1	23	141	163	141	163	0.98
2	14	0.004	0.6	12.1	0.5	2	23	168	189	167	189	0.95
3	14	0.00084	0.12	14.2	0.9	1	23	194	217	194	217	0.92
4	14	0.0051	0.76	11.8	5.0	1	23	223	245	223	245	0.97
5	14	0.0052	0.78	11.7	3.2	1	21	354	374	354	375	0.96
6	14	0.015	2.2	10.3	4.9	2	23	391	412	390	412	0.95
7	14	0.0002	0.03	16.2	0.1	1	23	418	441	418	441	0.96
8	14	3.9e-05	0.0058	18.4	1.0	3	23	453	473	451	473	0.95
9	14	0.00013	0.019	16.8	2.8	1	23	479	501	479	501	0.98
10	14	3.3e-05	0.005	18.6	0.3	2	23	507	528	506	528	0.97
11	14	7.2e-06	0.0011	20.7	0.3	1	23	533	555	533	555	0.98
12	14	3e-05	0.0045	18.8	0.2	1	23	561	584	561	584	0.97
13	14	0.00035	0.051	15.5	1.0	1	23	590	613	590	613	0.97
14	14	0.00032	0.048	15.5	4.9	1	23	619	642	619	642	0.97

Sequence Information

Coding Sequence: ATGAGAACCTGTCGTTCGTGTTTATCTGATACATtcgataatataaatttatttgaaactcTTTTTGAACAACGTAATGGTGGTTCGAATCATAAGGAAATCGAAGTGTCAACTATATTCCATGAATGCACGAATATTCGCCTGATTGAAAATGACAAAATGCCCAAACATATTTGCTTAAAGTGTTTAGAACAATTAATCAGCGTCTATGAATTTATactaaattgtaaacaaaacgaTATTAAATTACAAGAGATTATTGATTTTGGTCGCGTTAATATTGTACAGTCGCTAAATAGTTGTAATGGATCATATTCCAATTGTGAAAGTGATTGCAGTATTTCCGATAATTCAGATTATCAGGTTGATACGAGAGGTGAAGCGGATATAAAATTAGCCAATTCATCAGATGAAGGTAGTCATAAATGTTTGAAATGTTCGAAAATATTCACAACATCGGCCAAACTGAAAAAACATCAACGAATTCACACAGGTAATTGGAACTGTCCAGAATGCGATCGAGTTTTGGCAAACAAACATTCGCTACGTTTCCACATGATTTTGCATACGGGGAAACCCCATGAATGTATCGTATGTGAAAAACGTTTCGTATCCGTGTACGAACTTCGGCGGCATatcaaaatttatcataaaaatggCAAGAGTCATGTGTGTGATCAATGCTCCAAGCGATACTACACTTTTAATCaacttaaaaatcataaacttaCTCATTCAAAACAAGCAGATAAAGAATTTAAGCCGAAGTTCGAGGATGAATGCGAGaacgaaaatataaatcaagacGGCGAACTTATTACTGGCGATAATGAGCCCATTCTAGAAACGGAGTCTGTACAAATTGAAGAAATTAGTGTAGAAACGGAGtctataaaaattgaatcgtaCGAGATGGCGATTACCGAGCCAATAATTAAAGCGGAAAACGATTCGACTGTAGATAATGAAATTGAATTCGAAAATGACGAACAACCATTTAGCGATTCGGCGAACGAAATGTCATCGGACAGTACGGATTCAAAACAAGAAAGAACATTTTATCGTTGTAAAAGCTGCTTCAAGAAATTCAGACTTAAGAGTAATTATTTGAGTCatctaaagttaaaattaaattgtaaggCGGATTTGAATACAAAGACAAACCCTCAAAAATGCGAACATTGCAATACAATATGTGATAATTTGTATCAGTTAAGGAAACATCTAGAATTTCATTTGGATAAGGATCCATTTAAATGCCCCGCCTGTGGAAAGGTGTACAAATCTTGGATTAAATTAGCAGGACACAAGCGCCAAGTTCATTCTACAAAGCCGGTAACTCGTAAACCACATTTATGTACGCTCTGTGGAAAGGGATTTAGCTCGTCAAAATTATTGGAAGATCATTATATGGTACATCAGGGCGTGCGAAATTACAAATGCGATCAATGTGAACGATCATTTTGTACCATTTACGGTCTAAAACAGCACCTCACGATTCATACGCGAGACGCTCTTCAGTGTAGCGAATGTGGAAAAATTTTGGCaaataaaatgtctttaaaAAATCACATGACAATTCATTTTGGTAAAGATTATCCATGTACGATGTGTGACAAACGGTATCCCGATACGGCAACGTTAAATCGACATTTAAAAGTGCATCGGGGCGAACGGAATTATGCATGCGATCAATGTGGGAAGCGATATTATCGAGGCGGTGATTTAAACGATCATATACGAAAAATACATGAAAATCCTATGGATTTTAAATGTGAAGTATGCGATAGCGGATTTGGTCATAGACGGGCATTGAAAAAGCATGTTCGACTGGTGCACATCggtaagaaaatatataaatgcgaCAGTTGTGGTAAAACTTACGATCGTAAATCTAGATTAAAAGATCATGAGAAGAAATGCCATCCAATTGTGACGAATAGTCTTATTTTCACACGAGGTTGTGTTAATGCATGGATTAAACGTATCTTAATAGTAGATAAAACTGGACATTCCGGAACATTTGATCCTAAAGTAACAGGTTGTTTAATTGTCTGTATTGATCGAGCCACACAAttgataaaataa
Protein Sequence: MRTCRSCLSDTFDNINLFETLFEQRNGGSNHKEIEVSTIFHECTNIRLIENDKMPKHICLKCLEQLISVYEFILNCKQNDIKLQEIIDFGRVNIVQSLNSCNGSYSNCESDCSISDNSDYQVDTRGEADIKLANSSDEGSHKCLKCSKIFTTSAKLKKHQRIHTGNWNCPECDRVLANKHSLRFHMILHTGKPHECIVCEKRFVSVYELRRHIKIYHKNGKSHVCDQCSKRYYTFNQLKNHKLTHSKQADKEFKPKFEDECENENINQDGELITGDNEPILETESVQIEEISVETESIKIESYEMAITEPIIKAENDSTVDNEIEFENDEQPFSDSANEMSSDSTDSKQERTFYRCKSCFKKFRLKSNYLSHLKLKLNCKADLNTKTNPQKCEHCNTICDNLYQLRKHLEFHLDKDPFKCPACGKVYKSWIKLAGHKRQVHSTKPVTRKPHLCTLCGKGFSSSKLLEDHYMVHQGVRNYKCDQCERSFCTIYGLKQHLTIHTRDALQCSECGKILANKMSLKNHMTIHFGKDYPCTMCDKRYPDTATLNRHLKVHRGERNYACDQCGKRYYRGGDLNDHIRKIHENPMDFKCEVCDSGFGHRRALKKHVRLVHIGKKIYKCDSCGKTYDRKSRLKDHEKKCHPIVTNSLIFTRGCVNAWIKRILIVDKTGHSGTFDPKVTGCLIVCIDRATQLIK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01054603; iTF_01053672; iTF_01052508; iTF_01460494; iTF_01457759;
90% Identity: -
80% Identity: -