Basic Information

Insect: Tipula unca
Gene Symbol: -
Assembly: GCA_951394425.1
Location: OX596380.1:222625790-222637778[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 7.1e-05 0.011 17.6 0.2 3 23 127 147 126 147 0.97

2 10 2.5e-06 0.00038 22.2 1.2 1 23 153 175 153 175 0.99

3 10 5.1e-07 7.5e-05 24.4 2.7 1 23 181 203 181 203 0.98

4 10 2.7e-05 0.0041 18.9 1.6 1 23 213 235 213 235 0.99

5 10 1.3e-06 0.0002 23.0 2.0 1 23 241 263 241 263 0.98

6 10 0.00095 0.14 14.1 0.0 1 23 270 292 270 292 0.95

7 10 2.4e-05 0.0036 19.1 1.1 1 21 298 318 298 319 0.96

8 10 0.00048 0.071 15.0 0.3 1 20 322 341 322 344 0.93

9 10 3.2e-05 0.0048 18.7 0.7 2 23 351 372 350 372 0.97

10 10 2.4e-06 0.00036 22.2 1.4 1 23 378 401 378 401 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	7.1e-05	0.011	17.6	0.2	3	23	127	147	126	147	0.97
2	10	2.5e-06	0.00038	22.2	1.2	1	23	153	175	153	175	0.99
3	10	5.1e-07	7.5e-05	24.4	2.7	1	23	181	203	181	203	0.98
4	10	2.7e-05	0.0041	18.9	1.6	1	23	213	235	213	235	0.99
5	10	1.3e-06	0.0002	23.0	2.0	1	23	241	263	241	263	0.98
6	10	0.00095	0.14	14.1	0.0	1	23	270	292	270	292	0.95
7	10	2.4e-05	0.0036	19.1	1.1	1	21	298	318	298	319	0.96
8	10	0.00048	0.071	15.0	0.3	1	20	322	341	322	344	0.93
9	10	3.2e-05	0.0048	18.7	0.7	2	23	351	372	350	372	0.97
10	10	2.4e-06	0.00036	22.2	1.4	1	23	378	401	378	401	0.97

Sequence Information

Coding Sequence: ATGTTTGAACAATCGATAAAAGCGGAACCAATGAGTTTTTATACCGCATGTCAACCGCCACCACCTCCACCTCCAGCCATATTACAACAGCAAGCCACATCTCAGCACCAGCAAACCACTCAATTAATAACTCAAGCGATAGCAGCACGAACACCAAATGCTCAGGCAGATGGTCAAAGTAGAAATACCAGTAGTACTAGTGTGCCAGAATGGCGGGCACGCCTCAACGAGGCTGAACAAGTTGGTgaagtgaaattttttCCACAATCTGCCAATACTCCACTAACGACAATCTCTGAAGTTACAAAACAAGAATTAACCTTGTTAACATCAGGCCAAGCAAATACTCATACAAATTCACGTAGTAAGCCGCAGGCATGTAAAATTTGTGGGAAAATGTTATCGTCGGCAAGCAGCTACTACGTTCATATGAAACTCCACTCAGGAACAAAACCGTTTCAGTGTACGGTTTGTGAGGCAGCTTTTTGTCGTAAGCCCTATTTAGAAGTTCATATGAGAACACACACGGGCGAGCGACCATTTCAATGTGACGTATGTACGAAACGTTTTAGTCAAAAATCATCGTTGAATACTCATAAACGGATACATACAGGATATTGGACCATGCACAAACCATTTCAGTGTACCCAGTGTAATGCAGCATTTTGTCGGAAACCCTATCTCGATATTCATATGCGAATTCATACGGGTGAACGACCATTCGAGTGTGAAATATGTTTTAAACGCTTCACACAGAAATCGACGCTAAATATTCATAAGCGGATACATTCAGCTCAAGGACGGCCGTATCCGTGCATAGAATGTCCAGCCGCTTTTACACGGAAACCCTATCTCGATATCCATATGCGGATACATACGGGCGAAAAACCATTTCAGtgtcaaatttgtttgaaaCGTTTTACCCAGAAGTCAACATTGAATATCCATAAGCGGGAACGTCCATATGCATGCGATATCTGTAATAAAACATTTGCGGTCAAAAGCTATGTAACCGCGCACAGGTGGTCTCATGTATCCGAAAAACCGTTGAGCTGTGATCGCTGTTCAATGACATTCACAAGTAAAGCCCAATTTGCTGTGCACATTCGAACTCATTCGGCCGGTCAGAATTACGAATGTAACGTATGTGGGCGTACATTTATTCGCGATAGCTATCTAATTCGGCATCATAATCGAGTGCATCGTGAAAATCGTACGACAGCGAATAGCATAGCGACGATAAATAGCGTAGCACAGGGAGCGCATCATCATCTGATGGGAGCACCGAACGGGGCACATGGTCATGGAAGCCATCACGGGCCAAATTCTAGTAGTAGCACAGGCAGTGCTAATGCGGCCAGCGATGCGTATCCATCAAGTCGAAATCACAATCAGGTTTGTGATCTTAGATTTGTGTCCGGGTTACAAATGAATGCCTCATCAGCCGTATCGCAACTGTCATCACCCGGTGGACTGATGAGTAGCAGTGATCGCAGCAGTCGAATAAATGGATCATCCACGTCACAACCACCGTCAGGACAATTGCCAGGTAGCAATGGTACGGTTGTTATACAACAAAACGATAGAAATACTAATAACACTAATAGTAATAATCAAGTACTGAATcctatcaataataataataatagtagtagtagtaataataataatggcaataatagtaataacaatagtaataatagtaatccAGATAATCGTAACAACCTTGTTAATATAGATTTAAATGATCGATTAATGCAGGAACGTCTCGTTTTACAAAATCGTGCAATACAAGAGCGGGCGCTCCATGAGATGGCACTGCAGGGACGCGCAATACAGGAACGTGTACTAAACGAACGCAGTATATTACATCATCCGCCGTTAATAATACCAGGTCATGTGATTACGCACGATCGTCTTGTAGATAAAAGTTTATTGGCCAGTCCGGGACCTGTTTGA
Protein Sequence: MFEQSIKAEPMSFYTACQPPPPPPPAILQQQATSQHQQTTQLITQAIAARTPNAQADGQSRNTSSTSVPEWRARLNEAEQVGEVKFFPQSANTPLTTISEVTKQELTLLTSGQANTHTNSRSKPQACKICGKMLSSASSYYVHMKLHSGTKPFQCTVCEAAFCRKPYLEVHMRTHTGERPFQCDVCTKRFSQKSSLNTHKRIHTGYWTMHKPFQCTQCNAAFCRKPYLDIHMRIHTGERPFECEICFKRFTQKSTLNIHKRIHSAQGRPYPCIECPAAFTRKPYLDIHMRIHTGEKPFQCQICLKRFTQKSTLNIHKRERPYACDICNKTFAVKSYVTAHRWSHVSEKPLSCDRCSMTFTSKAQFAVHIRTHSAGQNYECNVCGRTFIRDSYLIRHHNRVHRENRTTANSIATINSVAQGAHHHLMGAPNGAHGHGSHHGPNSSSSTGSANAASDAYPSSRNHNQVCDLRFVSGLQMNASSAVSQLSSPGGLMSSSDRSSRINGSSTSQPPSGQLPGSNGTVVIQQNDRNTNNTNSNNQVLNPINNNNNSSSSNNNNGNNSNNNSNNSNPDNRNNLVNIDLNDRLMQERLVLQNRAIQERALHEMALQGRAIQERVLNERSILHHPPLIIPGHVITHDRLVDKSLLASPGPV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01456663;
90% Identity: iTF_01457770;
80% Identity: -