Basic Information

Insect: Tipula unca
Gene Symbol: -
Assembly: GCA_951394425.1
Location: OX596380.1:52166466-52172954[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 22 0.1 15 7.7 3.8 3 23 174 194 172 194 0.96

2 22 0.014 2.1 10.4 0.2 2 23 203 225 203 225 0.96

3 22 7.6e-05 0.011 17.5 1.1 1 23 232 254 232 254 0.96

4 22 0.044 6.6 8.8 1.7 1 23 260 283 260 283 0.96

5 22 0.018 2.7 10.0 7.0 1 23 288 310 288 310 0.98

6 22 0.49 72 5.5 6.9 1 23 316 334 316 338 0.73

7 22 4.9e-07 7.2e-05 24.4 2.7 1 23 344 366 344 366 0.96

8 22 0.00026 0.039 15.8 0.5 1 23 372 394 372 394 0.97

9 22 8.8e-08 1.3e-05 26.8 0.8 1 23 400 422 400 422 0.99

10 22 6.9e-05 0.01 17.6 1.4 1 23 428 451 428 451 0.96

11 22 2.8e-06 0.00042 22.0 0.3 1 23 509 531 509 531 0.98

12 22 8.6e-05 0.013 17.4 1.9 1 23 537 560 537 560 0.92

13 22 8.1e-06 0.0012 20.6 2.5 1 23 566 588 566 588 0.97

14 22 0.0013 0.2 13.6 4.5 1 23 594 616 594 616 0.98

15 22 0.44 65 5.7 0.1 1 12 622 633 622 638 0.88

16 22 0.002 0.3 13.1 0.2 2 23 762 784 761 784 0.96

17 22 3.5e-05 0.0051 18.6 0.4 1 23 791 813 791 813 0.97

18 22 0.08 12 8.0 1.4 1 23 819 842 819 842 0.96

19 22 1.6 2.3e+02 3.9 9.9 1 23 847 869 847 869 0.98

20 22 0.49 72 5.5 6.9 1 23 875 893 875 897 0.73

21 22 2e-07 3e-05 25.6 1.3 1 23 903 925 903 925 0.96

22 22 0.00042 0.062 15.2 2.3 1 23 931 954 931 954 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	22	0.1	15	7.7	3.8	3	23	174	194	172	194	0.96
2	22	0.014	2.1	10.4	0.2	2	23	203	225	203	225	0.96
3	22	7.6e-05	0.011	17.5	1.1	1	23	232	254	232	254	0.96
4	22	0.044	6.6	8.8	1.7	1	23	260	283	260	283	0.96
5	22	0.018	2.7	10.0	7.0	1	23	288	310	288	310	0.98
6	22	0.49	72	5.5	6.9	1	23	316	334	316	338	0.73
7	22	4.9e-07	7.2e-05	24.4	2.7	1	23	344	366	344	366	0.96
8	22	0.00026	0.039	15.8	0.5	1	23	372	394	372	394	0.97
9	22	8.8e-08	1.3e-05	26.8	0.8	1	23	400	422	400	422	0.99
10	22	6.9e-05	0.01	17.6	1.4	1	23	428	451	428	451	0.96
11	22	2.8e-06	0.00042	22.0	0.3	1	23	509	531	509	531	0.98
12	22	8.6e-05	0.013	17.4	1.9	1	23	537	560	537	560	0.92
13	22	8.1e-06	0.0012	20.6	2.5	1	23	566	588	566	588	0.97
14	22	0.0013	0.2	13.6	4.5	1	23	594	616	594	616	0.98
15	22	0.44	65	5.7	0.1	1	12	622	633	622	638	0.88
16	22	0.002	0.3	13.1	0.2	2	23	762	784	761	784	0.96
17	22	3.5e-05	0.0051	18.6	0.4	1	23	791	813	791	813	0.97
18	22	0.08	12	8.0	1.4	1	23	819	842	819	842	0.96
19	22	1.6	2.3e+02	3.9	9.9	1	23	847	869	847	869	0.98
20	22	0.49	72	5.5	6.9	1	23	875	893	875	897	0.73
21	22	2e-07	3e-05	25.6	1.3	1	23	903	925	903	925	0.96
22	22	0.00042	0.062	15.2	2.3	1	23	931	954	931	954	0.97

Sequence Information

Coding Sequence: ATGTCTAGTCTTCATATAtctgaaattaattataagaaaacaTGTCGTACATGTTTGAAACAAGAAAAAGATGGTATCAGTTTAAAGCAAATATTTTGTAAGGCCATAACTCCAATGGCAATACCAGATGAACTATCCAAAATGAGACTGAAGGTATCCAAAGACGATGGTTTGCCGCAATCAATATGCAATGAATGTGTTGATAGTTTAAtctttatacataaatttcggAAGTTATGTGAAAAGTCACAAGTAATACTAGACCTGTCTCATACATCCGAAAAACAAGCATCGATTGATATGTCGACTCACCATGAGTTAGAATTTGTTAATGTTGGATTTCTGCTCAACTCGCAGGATGAAATTGAAACGGAaccaaaattggaaattcagttgaaagaaaaaattctaTCCGATGACGATGTCACGTGCACGAGTGATGCATGGAATCAAAATGATTTGCTTGAATCTGTGTTACAGTCggaggaaaatcaaaataataccaacataaatcaaatttgctTCAGATGTGGCCAATTTTGTTCGAACAGCGAAGAATTGATGCTGCATCACGAGAAACATATTTGTGAGACTAGATCAAATCCAACTTGTCGTTATTGTAAAGAAATTTTCGAGACAATCGATTTGCTGGATATTCACATAAAAAGTGATCATCCAATAAAGAATCACACGCATATTTGCCCAATATGCGGGAAAAATTTTGCTACTGCACATAGTCGAAAGATACACATTGAATCGCACAGTGATAATTTTCCTTACGCATGTGATATTTGCGACAGtgcatttaaatgtaaaatttatctaaCCAAACATAAAAAGGTTGTGCATACATTTGGAGAACATGAATGCCCACATTGTTTTATGACATTCAATAGTACCTATAAGTACAACTACCACTTAAAAACGCACAATCCGAATAAGAAGTATAAATGCAAATATTGTGATAAATCATTTTTACTACGGCACCATCATGCTAATCATGAACGAATTCACACAGGATTAAAACCGTATTTATGCAATATTTGTGGCAAACATTTTCGAcaagaatataatttaacactTCATCTTCGCACTCACGGCGGCTCTCGTCCACATGTATGTGGACTGTGTGGTAAAGATTTTGCGCAACCAAGATCGCTTATACTGCATAACAAAAAGCATACCGGTGTCCGCCCATATCAGTGCGAACAGTGTGGTAAAGAGTTCTACCAAAAATCTGGTTTAAATGTGCATTTGCGAACTCATACTGGGGAACGCCCGTATAAATGTGACTTGTGCAGTAAAACTTATACACAATCCGCACAAttgaaatatcataaaatttcagTACATGATGTATTGATACCGGTTGATCAGAGAGCAAAAGATTTAAAGGACGGGAATACGGTTAATCCTCCAATCAAAGAGGGTATAGCTTCTAAAGTCAATTCAGAAAATTATGCCGAAACTTCAAATGAATCGgaatctattaaattaaaagaaacggCGACCAATCGTTTCTTATTTGAATGCAGTATAtgcacaaaacaatttaaattgccATCATCGTTGGCCGCGCATATAAAAACCCATTCAGAGAACCGCAAACACGTGTGTACAGAATGCGGCAATTCGTTTAAGCGTGCCGAACATTTAAAGATTCATTTTAATGGGGTTCATCTAAAACAGAAACCGTATGCATGTAAAATTTGCCataaaaccttttctcaatcTGGCGATCGAAATAAACATATGATCTCACATTCAGATGAGAAACCACATAAGTGTCCACATTGTTCGAAACGGTTTGGATTACAAAAAGTTCTTAAAGACCATGTCAGAACACATACGGGAGAAACACCATATAAATGTGAAATTTGTAATATGGGCTTCATCACCTATAATGCCGTAATATCCAAACACGATGGTTTACCGCAATCAATATGCAATGAATGTGTTGATAgtttaatctatatacataaatttcggAAGTTATGTGAAAAATCACAAGAAATACTAGACTTATCTCATACAATCGAAAAACCTGTGTCGATTGAAATGTCGACTCGCCATGAGTTAGAATTTGTTAATGTTGGGGTGGTCCTCAACGCAGAAGATGAAATTAAAACGGAACCTAGATTGGAAATCCAGTTGAACAAGGAAATTTTATCCGATGACGATGTTACACGCTCGAGTGATACATGGAAACAAAATGATTTGGTTGAATCTGTACTACAGtcggaagaaaatcaaaataattccaacataaatcaaatttgctTGACTTGTCGTTATTGTAAAGAAATTTTCGTGACACTCGATTTACTGGATATTCACATAAAAAGTGATCATCCAATAAAGAAACACAAGCATATGTGTCCAATATGCGGGAAAAATTTTCCCACTCCACAAGGTCGAAAAAGACACATTGAATCGCACAATGATAATTTTCCTTACGCATGTGATATTTGCGACAGTGcctttaaatgtaaaatttatctaaCCCAACATAAAAAAGTTGTGCACACATTTGAAGAACATGAATGTCCACATTGTTTTATGAAATTCCATAGTACCAAAAAGTACAACTACCATTTAAAAACGCACGATCCGAATAAGAAGTATAAATGCAAATATTGTGATAAATCATTTTTACTACGGCACCATCATGCCAATCATGAACGCATTCACACAGGATTGAAAccatatttatgtaatatttgtGGTACTTCTTTTCGACAAGACTATAATTTAACACGTCATCTTCGCACCCATTCGGAGGGACGACCGTATAAATGTGAGTTGTGCAGTAAAGCTTATAAACAAtccacaaaattgaaatatcacAAAATGTCGGTACATGATATATTGATCCGATTGATCAGTGAGCCAAACATTTAA
Protein Sequence: MSSLHISEINYKKTCRTCLKQEKDGISLKQIFCKAITPMAIPDELSKMRLKVSKDDGLPQSICNECVDSLIFIHKFRKLCEKSQVILDLSHTSEKQASIDMSTHHELEFVNVGFLLNSQDEIETEPKLEIQLKEKILSDDDVTCTSDAWNQNDLLESVLQSEENQNNTNINQICFRCGQFCSNSEELMLHHEKHICETRSNPTCRYCKEIFETIDLLDIHIKSDHPIKNHTHICPICGKNFATAHSRKIHIESHSDNFPYACDICDSAFKCKIYLTKHKKVVHTFGEHECPHCFMTFNSTYKYNYHLKTHNPNKKYKCKYCDKSFLLRHHHANHERIHTGLKPYLCNICGKHFRQEYNLTLHLRTHGGSRPHVCGLCGKDFAQPRSLILHNKKHTGVRPYQCEQCGKEFYQKSGLNVHLRTHTGERPYKCDLCSKTYTQSAQLKYHKISVHDVLIPVDQRAKDLKDGNTVNPPIKEGIASKVNSENYAETSNESESIKLKETATNRFLFECSICTKQFKLPSSLAAHIKTHSENRKHVCTECGNSFKRAEHLKIHFNGVHLKQKPYACKICHKTFSQSGDRNKHMISHSDEKPHKCPHCSKRFGLQKVLKDHVRTHTGETPYKCEICNMGFITYNAVISKHDGLPQSICNECVDSLIYIHKFRKLCEKSQEILDLSHTIEKPVSIEMSTRHELEFVNVGVVLNAEDEIKTEPRLEIQLNKEILSDDDVTRSSDTWKQNDLVESVLQSEENQNNSNINQICLTCRYCKEIFVTLDLLDIHIKSDHPIKKHKHMCPICGKNFPTPQGRKRHIESHNDNFPYACDICDSAFKCKIYLTQHKKVVHTFEEHECPHCFMKFHSTKKYNYHLKTHDPNKKYKCKYCDKSFLLRHHHANHERIHTGLKPYLCNICGTSFRQDYNLTRHLRTHSEGRPYKCELCSKAYKQSTKLKYHKMSVHDILIRLISEPNI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -