Tlat032665.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tipula lateralis
Gene Symbol
zfh1
Assembly
GCA_963932295.1
Location
OZ010738.1:185019110-185031830[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.009 1.2 10.9 4.6 2 23 52 74 51 74 0.96
2 9 0.00098 0.13 13.9 0.3 1 23 164 186 164 186 0.95
3 9 1.9e-05 0.0025 19.3 1.9 2 23 193 214 192 214 0.97
4 9 3.8e-06 0.00049 21.5 5.9 1 23 223 245 223 245 0.99
5 9 7.3e-05 0.0094 17.4 1.2 1 21 251 271 251 272 0.94
6 9 0.00049 0.063 14.8 1.1 2 21 541 560 540 561 0.92
7 9 6.5e-06 0.00084 20.7 0.9 1 23 873 895 873 895 0.94
8 9 5.9e-05 0.0076 17.7 7.2 1 23 901 923 901 923 0.98
9 9 0.0027 0.35 12.5 4.3 1 21 929 949 929 950 0.96

Sequence Information

Coding Sequence
ATGTTGTCTTGTTTAGTGCCTCGTTTCGGACAAGAGACAGACAAAATCAGTAATATAATGCCATCATCGCCTGCTTTTACCATGCAATttcCATCGCTGGTATCAGGCTTGCCAAAGGACGATGAAAGTACTGGCCATTcagaattttttatgaaatgtcAGCAATGTCACCAACATTTTACAGACTTTCAGTCATTGAAAGAACATTTGGATACAGTACATTCGATTGACAAGAAACCCCAATATCTAAATCATTTCAATCAATTAGGTTCATCAGGTACACCGTCACCCCCTATActacataataacaataataataatattagtaacaataataataataataatttaattaatcacaataatcatcatcaacaacatCAAATACCATCAGCATCACAATCTATAAAGGACGAATGTGGGCGTTCAACGACGAGTCCTAATACATCACAACCTCAACATCATCATAATAATTTGGGAGCAGGACCTCACGCATGCTCTCAGTGCCCCGCCTCATTTCCAAACCGTGATTCATTAGATAAACATGAATTAATGCATTCACCTAGTTCTACTGTGAGttgtaaaatttgtcataaGACATTCGCAAATGTATACCGTCTACAGCGACACATGATAAGTCATGATGAATCAGCCCTGCTTCGCAAATTTAAATGTACCGATTGTGACAAagcgtttaaatttaaacatcacCTCAAAGAACACGTTCGTATACACTCGGGGGAGAAACCATTCGCGTGTAACAATTGTGGTAAAAGATTTAGCCACAGTGGATCGTATTCGAGTCATATGacatcaaaaaaatgtataagcatgggtctaaaattaaataatacgcGTGTTATGAAAACAAACGAGAAAAATTATCGAATGAAAGAGGAGATGATGGCGGGTTTTGGGTCACCAAATCGGCCAAATTTTTTAAGTCAAAATTTGGCACGCGTCGGTCTTAATAACATCAACAATGGTATGAATAATGGATCAAGTGCCAACCACAATAATTTTCTGTCGTCAATATTCCCAAAAGGTAATAATTATGATGCAATGAATGCGGCTCTTTTTGCCTCAACGTTTGCCCACCCGTTTTTACCAATGCCATTCGATCCACGAACCACATACAATTTACAACGATTTTTTGAACTGACAGCTGCAAGTTCGTCACAAACTAACGCGGTTGAATCATTGCTTCAGAATAATTTCCAcaacaatcataataataataataacacgcCTAGTTTGCATTCGGACCCCGAGGATATGATCGAAGAAGTTACCGAGGATGTTAATGATGAACCTAAATTAGTTATGGATTTGGGTGACGAAGAGGATAAACCCGAGGTTATTGAAGAACCAGTGCATAAAAGTGTCGAATCACCACATCATGTTAAGGATGTAGAACATCCACCGACGGACGACGATGATATAAAGAACGATCTAAATATTGATGTCGAAGAAACAGCCGCTGTTCCAGAAAATTTATCTCGAGAAAGTATGAAAACAGATTCTCCAATTTCATTGGATTTAAAAGATAATGATCGACCTCAAACACCACAAACTCCCGATGACCACCATATAAAAGATGAAATGAAAGATGATTCATTACAGTGTTCTCGCTGCGATAAAACTTTTAACCACCGTACCGAATTGTTACAACACGAAAAAGTTTTGTGCGGTCTGTTTCGAAAGCACGAAGGGCTCGCAGCACAAATGGCTGAAACTATTGCTTTAAATGGTAACTACTTATCGATGGCGTCGGGTAGTGAAGATGAAGATCGTGATTCACGACACTTATCGGAAGGTGAACGTAAAGTTCGTGTACGAACCGCAATATCGGAAGAGCAACAAATAGTATTAAAAGAACATTATGCTGTTAATCCTCGTCCAAATCGCGAAGAATTCCGTACGATAGCGCAACGATTAATGCTCGATCCACGAGTCGTACAAGTTTGGTTCCAAAACAATCGATCACGTGAAcgaaaactaaataatattccCTTTAAGAAGGACTATTCAATACAACAACCTCTATTCGGCAGTAGTGGTGGTGGTAGTTCGATTTCGCCTAGTTTAAACTCTCCCGCCATGGAATACGATCAGCCACTCGATTTATCGATCAAAAAAGAATCTCCAGCCACAACACCGTCAAGCTCGCCAAATTACGGAAGCCACTTAAACCAATCCGACAATTCGATTTCGGATGAAGTAATGAACTTAAGCCTTAAATCGGAACAGCAAGGCGTAACACCATATCGACATTTATTTAACTATGGTGTCGCACTTACAAATCGTTCTTCTGAATCGCAAACACCATCACCTAGTCAAGCACATACGCCATACCATCAGTACACGAATATGTTTCCAAACCCGTTGGGCTTGGTACCAATGGATCGCCTTTTACAAATGACACCAGAACTACCCAGAAGCTCATTACTAGGATTTAAAACGGAACGCGACAATAGTTTAAGTCCAGGCTATGATAAATCATTGTGGAAGGATGAAAATTCAATGCGCACCCTCAACGATATAAGTGCCAATTTTATGCAGCATTTACCGAAGCGAATGCAGCACACGGGAAAGGAACAAGAAGCGGAAGGACAATTTGTATGTGATCAATGTGATAAAGCATTTAGTAAGCAAAGCTCACTCGCGCGACATAAATACGAACATTCAGGTCAACGGCCATACAAATGTGTCGAATGTCCGAAAGCGTTCAAACATAAACATCACTTAACCGAGCATAAACGTCTGCACAGTGGTGAAAAACCATTTCAATGTTCGAAATGTTTAAAGCGTTTCTCCCACTCGGGATCATACAGCCAGCACATGAACCACAGGTACTCGTATTGTAAACCGTATAGAGAATAG
Protein Sequence
MLSCLVPRFGQETDKISNIMPSSPAFTMQFPSLVSGLPKDDESTGHSEFFMKCQQCHQHFTDFQSLKEHLDTVHSIDKKPQYLNHFNQLGSSGTPSPPILHNNNNNNISNNNNNNNLINHNNHHQQHQIPSASQSIKDECGRSTTSPNTSQPQHHHNNLGAGPHACSQCPASFPNRDSLDKHELMHSPSSTVSCKICHKTFANVYRLQRHMISHDESALLRKFKCTDCDKAFKFKHHLKEHVRIHSGEKPFACNNCGKRFSHSGSYSSHMTSKKCISMGLKLNNTRVMKTNEKNYRMKEEMMAGFGSPNRPNFLSQNLARVGLNNINNGMNNGSSANHNNFLSSIFPKGNNYDAMNAALFASTFAHPFLPMPFDPRTTYNLQRFFELTAASSSQTNAVESLLQNNFHNNHNNNNNTPSLHSDPEDMIEEVTEDVNDEPKLVMDLGDEEDKPEVIEEPVHKSVESPHHVKDVEHPPTDDDDIKNDLNIDVEETAAVPENLSRESMKTDSPISLDLKDNDRPQTPQTPDDHHIKDEMKDDSLQCSRCDKTFNHRTELLQHEKVLCGLFRKHEGLAAQMAETIALNGNYLSMASGSEDEDRDSRHLSEGERKVRVRTAISEEQQIVLKEHYAVNPRPNREEFRTIAQRLMLDPRVVQVWFQNNRSRERKLNNIPFKKDYSIQQPLFGSSGGGSSISPSLNSPAMEYDQPLDLSIKKESPATTPSSSPNYGSHLNQSDNSISDEVMNLSLKSEQQGVTPYRHLFNYGVALTNRSSESQTPSPSQAHTPYHQYTNMFPNPLGLVPMDRLLQMTPELPRSSLLGFKTERDNSLSPGYDKSLWKDENSMRTLNDISANFMQHLPKRMQHTGKEQEAEGQFVCDQCDKAFSKQSSLARHKYEHSGQRPYKCVECPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01457225;
90% Identity
iTF_01455193;
80% Identity
iTF_01457225;