Basic Information

Insect: Tipula lateralis
Gene Symbol: -
Assembly: GCA_963932295.1
Location: OZ010736.1:63186869-63191667[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00015 0.019 16.5 0.8 1 23 156 178 156 178 0.95

2 15 0.0013 0.17 13.5 2.2 1 23 184 206 184 206 0.97

3 15 6.4e-05 0.0082 17.6 0.3 1 23 313 335 313 335 0.98

4 15 0.027 3.5 9.4 0.0 1 23 341 364 341 364 0.97

5 15 0.0012 0.16 13.6 4.1 1 23 395 417 395 417 0.96

6 15 0.18 24 6.7 0.2 1 23 432 454 432 454 0.94

7 15 0.13 16 7.3 0.1 2 23 461 483 460 483 0.95

8 15 0.23 30 6.4 2.7 1 19 490 508 490 509 0.96

9 15 0.00034 0.044 15.3 5.8 1 23 518 540 518 540 0.96

10 15 0.0036 0.46 12.1 0.4 2 23 546 567 545 567 0.97

11 15 1.1e-05 0.0014 20.0 0.4 1 23 575 597 575 597 0.98

12 15 0.0011 0.14 13.7 0.1 3 23 605 625 603 625 0.97

13 15 2.6e-05 0.0034 18.8 0.5 1 23 631 653 631 654 0.96

14 15 0.012 1.5 10.5 0.7 1 23 668 690 668 690 0.96

15 15 0.00022 0.028 15.9 0.1 1 23 1119 1142 1119 1142 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00015	0.019	16.5	0.8	1	23	156	178	156	178	0.95
2	15	0.0013	0.17	13.5	2.2	1	23	184	206	184	206	0.97
3	15	6.4e-05	0.0082	17.6	0.3	1	23	313	335	313	335	0.98
4	15	0.027	3.5	9.4	0.0	1	23	341	364	341	364	0.97
5	15	0.0012	0.16	13.6	4.1	1	23	395	417	395	417	0.96
6	15	0.18	24	6.7	0.2	1	23	432	454	432	454	0.94
7	15	0.13	16	7.3	0.1	2	23	461	483	460	483	0.95
8	15	0.23	30	6.4	2.7	1	19	490	508	490	509	0.96
9	15	0.00034	0.044	15.3	5.8	1	23	518	540	518	540	0.96
10	15	0.0036	0.46	12.1	0.4	2	23	546	567	545	567	0.97
11	15	1.1e-05	0.0014	20.0	0.4	1	23	575	597	575	597	0.98
12	15	0.0011	0.14	13.7	0.1	3	23	605	625	603	625	0.97
13	15	2.6e-05	0.0034	18.8	0.5	1	23	631	653	631	654	0.96
14	15	0.012	1.5	10.5	0.7	1	23	668	690	668	690	0.96
15	15	0.00022	0.028	15.9	0.1	1	23	1119	1142	1119	1142	0.93

Sequence Information

Coding Sequence: ATGGGGGAGGTACCACGAACCCTCCGAATCGATTGGGATATTGATGATGATATGCAACAAGAAATTATCAACGAGGAGGTAATTGAAATGAATAATACTGATGATGTCGACGATGAGTATTTGGTTGGTGAAGAAATTATACCTTCGACGGATGTGACAAATAGTTTAGATCATATAGCTGCCGAAAATTTAATCTATATGGCACATGATGGCCATGTACAGAGTATGGGTGATCTAATAGCCGAACAAGTAGAACAAGTTGAAAATGCAGATTACAATGagcaacaatattttgaatgtcaAGTCACCGAAGAGGTAATAACCGATGATTGGGTGCAGCAGCAAGGCGAGGAACGAGTTGAAATACCAGTCGATCAGTTATGTACAAGTGGCGAAGTAATCAATGAAGAAGATATGGATGTACCACTACCAACGGATCAAGATGAATATACAACATCGAGACCATATCCTTGTGATTTTTGTAGTCGGCGTTTTCGTAAGAAAGCGACACTTATGAATCATATGGTGGCCCATCAAAACGATCGACCTCATGTGTGCAATTTGTGTGGTGCCCGATATATACGGCGTTGTGATTTACTTAATCATTTGAAAATACATGCGTATGTACCAGAAGGTGGAGATTTAGAAGAATTGGAAAAAATACAAAAAGAGAATACagttaaattaaaacgaaaatacgAATCAAAACGTTACAAGTCGGAAAATCGTGTTTCAcccaaaaaactaaaaatggagCAGCATTCCGATGATACTACTGCATCAGTTAAATATGAGTATGTGCAGGACATGAAACTTCTTAATTCCGATGATAATGATGGGGATCAAGATGGTGTAGTTGAATCACAAAATGAAGATAGCTACGAAGAGGTTCATAACTCGTATATTCGTTATCCCGTTACCGATCCAAAAAAACCATTTGTATGTCAACATTGTGGGGTCGGGTTTGCGCGACAAAAAGCCTTAGCGTCCCACTCAAGGATTCATGGTGGAGATTCACCATTCGAATGTGAAACGTGTGGTGACATGTTTTGGGATCCGGCTGCGTTACGTGAACATCAACGATTGCAACATCAAGGTGAGGGAGCGGAATCGGAATACGAACCAGAAAATGACGAAAATGATGAAGATGCATCGGAATCGGAAGACTCTACTTTTGGTGGATTTTTCTGTGAAACCTGTGGAATGTCATTCCACCGATATGAATTACTAAAACGTCATTCTCGACAGCATGTCAAAAAAGAAATAACCGATAGTGAATTGGCCGGTGCTGGACATTGTTGCAATGTATGCGGTGATTCATTTGCTGAAGCTTTAGACTTGTTAGCTCATGCTGAGGTGCATGCAAGATGCCAACCTTTAAAATGTATGTTATGTGGTGAATCATTTCTCGAGGAATCAATGATAAAATCTCACATACGGATCGTACACGCAAATGAATTAACGCAACACTCGTGTCGCCTGTGTGGCAAATTATGTCGCGATAGTCGAACTCTAGCAAAACATTCATGGGAACATACGAGCGAAAGAAATCATTCCTGTTCGAAGTGTGGcaaaaatttccataataaaGCACGTCTAAAACGACACATGGTTTCTCATCGTAATAAAACTGTTACGTGTGATATGTGCGGTGAAGAATTTCCTGATGGACGGTCTCTTATGAATCATCGTCATTCACATACGAATGTCACAGGGCGGCAATTTCCTTGTCGCGAATGCGGTAAAACATTCGGTTCGCGTAGTTCACAACAAATTCATATACGCATTCATACGGGTGAACGACCATATGGGTGTCGATATTGTTGGAAAGCGTTTGCTGATGGTGGAACATTAAGAAAGCATGAACGTATTCATACAGGAGAAAAACCGTATGTTTGTTCAGTGTGTCCTCGAGCCTTTAATCAGAGAGTCGTATTGCGTGAACATATACGATCTCATCATTCGAGCCCCGATACAAAACGTGGCAATGCAGCTACACCATACTTTTGTCAAGTGTGCCACGAATTGTTTGTAACGTCGCTCGATTTAATTCAACATTTGATTCAACACAGTGATATGAACACGGCAATGAAGAGACAGCCGATTacGGGACCAAGAAAATATAAACGTAGAAGGAAATTAAAACCGCACGAGTTAGAAAAATTAAGAGCAGAAAAAAATGCAGGCAAACTGGGCGAAAACGACTATACCGATGATGATGAGCAGTATTTGCAAGATGAAGATGATAATTTCCAAGAGGAAACAATTACGTTTAATAAGACAACTCGAACACGGAATAATATGAGCTCCCAGATAGTTCAATCACCGCCACCATCTTCAGTATCCTCGTATACAGCAACTACGTCAGTGGTGGAAAATAAGAAATCGAATAAAaagaagaataataataatattgatgatgttgatacattaattaataatttaggtGCACCGATGGCATTAACTATTCCTTCGAATATAATGTCTACATCGATAACCACAAATAATGCTAAGCCGACCAAATCTACCAATAAAAAGAAGAAATCCGAAGATAATCAACCAACACGACCAAAAATGATACATACGCAAAAAACTCGAGTGCCAATCGAAGATGgtaaacgaaaaacaaaaacattagtTACATGGACGACACAATCGAGTGAAGGGCATAGTGGTACTggtagcaattcgaaaaatgaaCGGAATCGACCACGCACCAAAAATGTAAACTATCACATTCTAGTACCTGACAAATTACCTAATGCAACATTTTCAAACGAACTAAACGATATTATATCGATTAAAAACGAGGATcaggataataaaacaaatagttttacacTGCGGTACGATAAAGATATACTCGAAAGtgatataaatagttttggtaATTTAGGCAATCACCTATTTGAGTTGCCACGCAATagtttaaccaaatataataGTGACATTGTCAATGATTTAGAAGAAATTTTACGATCACCAATTAAGGGCCAAGCTATGAATCAATCATCGATGAATATGATATCACCTGGTGGTGGTGGTGATGGTACAACATCTGATGAAGCTGCCGATTATCATAATCAAatgttgataaataataatactacgGCTAGTGGACGCCCCAGACGTAATATTAAAcgtaaattctcatttaaaattgaatcaccACCGCATTCGACACCATCATCGTCGTCATCATCTTTGCGTAATAGTAATGGTAAGCAAACTAAATCATCAATTAAACGTAATAATAgcgctaataataataataataataatttaaaactaaaacttgaTTATTCAAATGTCATGATAAAATCAGAAAATGAGCTAATCATACCGGATAATTTGTACAAATGTGATATGTGTTCAGCGGTTTTTTCTGATCGGTCCCAACTATTGATACACGGGGCATCGATGCACATATga
Protein Sequence: MGEVPRTLRIDWDIDDDMQQEIINEEVIEMNNTDDVDDEYLVGEEIIPSTDVTNSLDHIAAENLIYMAHDGHVQSMGDLIAEQVEQVENADYNEQQYFECQVTEEVITDDWVQQQGEERVEIPVDQLCTSGEVINEEDMDVPLPTDQDEYTTSRPYPCDFCSRRFRKKATLMNHMVAHQNDRPHVCNLCGARYIRRCDLLNHLKIHAYVPEGGDLEELEKIQKENTVKLKRKYESKRYKSENRVSPKKLKMEQHSDDTTASVKYEYVQDMKLLNSDDNDGDQDGVVESQNEDSYEEVHNSYIRYPVTDPKKPFVCQHCGVGFARQKALASHSRIHGGDSPFECETCGDMFWDPAALREHQRLQHQGEGAESEYEPENDENDEDASESEDSTFGGFFCETCGMSFHRYELLKRHSRQHVKKEITDSELAGAGHCCNVCGDSFAEALDLLAHAEVHARCQPLKCMLCGESFLEESMIKSHIRIVHANELTQHSCRLCGKLCRDSRTLAKHSWEHTSERNHSCSKCGKNFHNKARLKRHMVSHRNKTVTCDMCGEEFPDGRSLMNHRHSHTNVTGRQFPCRECGKTFGSRSSQQIHIRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYVCSVCPRAFNQRVVLREHIRSHHSSPDTKRGNAATPYFCQVCHELFVTSLDLIQHLIQHSDMNTAMKRQPITGPRKYKRRRKLKPHELEKLRAEKNAGKLGENDYTDDDEQYLQDEDDNFQEETITFNKTTRTRNNMSSQIVQSPPPSSVSSYTATTSVVENKKSNKKKNNNNIDDVDTLINNLGAPMALTIPSNIMSTSITTNNAKPTKSTNKKKKSEDNQPTRPKMIHTQKTRVPIEDGKRKTKTLVTWTTQSSEGHSGTGSNSKNERNRPRTKNVNYHILVPDKLPNATFSNELNDIISIKNEDQDNKTNSFTLRYDKDILESDINSFGNLGNHLFELPRNSLTKYNSDIVNDLEEILRSPIKGQAMNQSSMNMISPGGGGDGTTSDEAADYHNQMLINNNTTASGRPRRNIKRKFSFKIESPPHSTPSSSSSSLRNSNGKQTKSSIKRNNSANNNNNNNLKLKLDYSNVMIKSENELIIPDNLYKCDMCSAVFSDRSQLLIHGASMHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01052518;
90% Identity: -
80% Identity: -