Basic Information

Insect: Tipula helvola
Gene Symbol: dis3l2
Assembly: GCA_963556165.1
Location: OY744483.1:64854368-64872135[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.064 24 8.4 3.3 1 21 1058 1078 1058 1081 0.89

2 8 0.00018 0.068 16.4 2.4 1 23 1113 1135 1113 1135 0.96

3 8 0.08 30 8.1 1.0 1 23 1155 1178 1155 1178 0.96

4 8 0.14 53 7.4 3.5 1 23 1183 1206 1183 1206 0.90

5 8 3.6e-06 0.0014 21.8 1.4 2 23 1211 1232 1210 1232 0.95

6 8 0.0091 3.4 11.1 0.2 1 23 1239 1262 1239 1262 0.91

7 8 0.00019 0.07 16.4 0.2 1 23 1268 1290 1268 1290 0.98

8 8 0.0032 1.2 12.5 4.0 1 23 1296 1319 1296 1319 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.064	24	8.4	3.3	1	21	1058	1078	1058	1081	0.89
2	8	0.00018	0.068	16.4	2.4	1	23	1113	1135	1113	1135	0.96
3	8	0.08	30	8.1	1.0	1	23	1155	1178	1155	1178	0.96
4	8	0.14	53	7.4	3.5	1	23	1183	1206	1183	1206	0.90
5	8	3.6e-06	0.0014	21.8	1.4	2	23	1211	1232	1210	1232	0.95
6	8	0.0091	3.4	11.1	0.2	1	23	1239	1262	1239	1262	0.91
7	8	0.00019	0.07	16.4	0.2	1	23	1268	1290	1268	1290	0.98
8	8	0.0032	1.2	12.5	4.0	1	23	1296	1319	1296	1319	0.92

Sequence Information

Coding Sequence: ATGGATGAATCCACGCATGAAACTATTTTGGAAGCCAATGCTGCTAAATGTAAAATCGAAGAGTTGATGGCAAAGCTTGCCGATTTAAAGGTAGAATTTACCAAAGTGGAAAATattacaacaaatattattgAGGAATCGGTAGCGGGCCCAAGTAACGTTTCTCAGATTAGTAAcaaggaaaatgaaaatatggaaaaacCGAAAAAGAAACGCGAAAGGAATAGAACAAAACCTAAAAAAGGTAAATTTAATGAGGAAATCGATATAACTGTAGAGGAATCGCCAAATGAGTTAAATGTTAATTTACATCTAGCtcaaagtaaaagtaaaaaaaaagataaacctGTTAAAAATCATGTTgagGCAATTACagataaatcaaaaatgaatgCTAATGTCTGTGATCCGAGTATCACAGTGACTCTGACACCAGAAACCATTctgatttataaattattgatcATGTCACCAGCAGACCGCGATAAATTCATCTATAAACAGGCAAAGGAGCGGCGCATATTGATTCGAAATATTCAAACGGatcttttcgaatttaatcCCATATTTTACGGTGGTACAGCACATCAATTTATAAAGCCCAATGATGACAATATGAATCGTAAAGAAAAGTTTCCTTACCATTTCGAAGAACGCAGAAACAAACGTAGCAGGAAACTTAAGTCAAGAGATGAAAAAtcgaaatcaaaacaaaataagttgTATGATTTGTTCGAAACTCAAGTTAATCGATTATTGTACGGGGAAAGTAAATTAACGGGGCAAGAAAAAGAAGAGGCGATATTTCTTTATAATGAGAATGGTGACAAGAAGAATAAACTATTTTCAACCGAagataatcaaataaatcttgaacaatttattcaaaaattgatcGATAAAGATTTGGGATACATCATCGAGAGTGAAATTcgtataaaccaaaaaaataatcatgaaGGGTATGTAACAAACAACTTAAATAGCGAAGGCGATATTCTAGTTCCTTCGATAGTACTCAGACAATGTGCTTTGCATGGTGATTCAGTTAAAGTTTTTGCTGTAAAACCAAATATGTATAACGGTAAGGAGAAGGCAGGAAATGAGGTTGAAGATATAAAAGTTATATCAATTGATAAAGATGGTGGTACCGAAAACGAGGATGAAGATAAAGATTTATGCCTAGCTGAAGTAATTGATGTACCGACACCTAATAAACCACGGGTTCTaggatttgttttaaaaataatggaaaaagtCAATACTAGACAATGTATTGGAACTTTTAAAAAGATTAGTAAAACGGCAGCTTCCATATTCAAACCGCGAGATTTAAAATTAcctcaaatcaaaataaatcccATACACATGCCAGAATCGTTGTTGAACCAAAAAGATTCAAGTGATGAACCTGATGCGGCACAAAATAATGTTGAAGAAATTCTATATTACGTTGAAATTATTGATTCATCGCATCATGAATTAATCGGTCGTATTATAAAACCAGTTGGAAAATGCGGAGagttggaaaatgaaaatcaagcTATTCTATTACAAAACGGCTTAAATCCAATTCAATTTTCAGATGATATATTGAAAGAAATTCCTGCAATACCATTTATGATTACGGACAGTGAATTTTCGAATCGTACCGATCTTAGAAATCAGTGTATCTTTACAATAGATCCTCCAACAGCACGTGATTTGGATGATGCGGTTTCTTCAAAAATTCTCCCTAATGGAAATTATGAAATAGGTGTTCACATCTCCGATGTATCGTATTTCCTCAAAGAAAATTCATtgattgatgaaaaaattaaaaatcagacGACTAGTATTTATCTAGTAGACAAAGTATATCACATGTTACcggaaaaattatgttttttatgctCATTAACGCCAGGAGAAGATAAATTAGCATTCTCCGTTATATGGGAAATTACTAAAACTGGTGAAATTTTAAAGACCGAGTTCAAACGAACAGTTATAAATTCTTGCAGCCAATTATCGTACGATCATGCTCAAGCAGTGATTGAAAATTCAGATAAAATATTCGATGAAATTTGTTTTCCGCACATATACAACAACTATAAACCTAGTGATTTAATAGAAGttgttaaacaattaaatacgaTTGCTCTCGTTTTACGTCAGCAAAGGTTTGATAATGGAGCCTTACGTATAAAtcagccaaaattaaaattcaatctcGATCACAGTAGCGGCAAACCGATTTCATATTATACAGAACGCCAACAAATCagtaattatttgattgaagaTTTTATGTTACTTGCCAATCAATCAGTCGCagcatttatttttgaaaagtttcctGATTTGGCTGTGCTTCGAAAGCACGATTCGCCAAACGAAACTGCTCTGATGAAAGTGACGACGAAACTGTCAGCgttgaatttaagatttgatatttcaaattccaagtccATTCGCGAATCGCTCGAAAAACTTCCTAAGCAGTGCAAGTCCGAAGAGGCGGGTAGTTCTgtactaaattttataactgCCAAACAAATGACTAGGGCGAAGTACATTTGTAGTGATCAAGTGACGTCAATAGAGGAGTTGAAACATTACGCTTTGTCAATTCCTATTTATACTCATTTCACAAGCCCAATTCGTCGATATCCTGATATATTGGTCCATCGTTTATTATGTGCTGGCCTAAATTTGGATAAGGTACCTGAACGTACAACAATCGagttaagtaaaattttgaaaaattgtaatcaacAAAAGATGGATGCCAAATCGGCTGGCGACGAAAGTGCTAATTTGTATTTCATCCATTACTTGAAAACTGTTGGTAGCTTAAAAATGCGTGCAGCTGTTTTGGAAATTATGGAGTATTCTatggaatttattattatggaaACGGGACACATTTTACGTATTCCATATAAAGTTTTAACTAATTCGAATGAAGATACATTTATTCTTAAATATGAATCAATAGCCACATCACCTTCTAAAAGGATCAAACTCGAAAAAGACGAGGATCCAATTTCGGAAGATAGTGAAGAATTTTACGATCCAATCTGTGAAGAAGTAAACGAGGTAAACGTAAGTCAAGTAAAATCCAAGAGGAGGAAGAGATCACCAGCTGAAAGTTGTGATGAACAAGAACCTGCCTCTAAAAGtaagaattttaattgtttacaatgcggtaaaatttatcgaaaaaagaACTCATTAATCACACATTCATATCATTATCACCCTGGATGGTGTCCTACTTGTGGTAAATATTACGGAACAACTGCTAAAGATTTAGGTGATCATAATAGAAAGTATCACATCAAAGATTATCCCCATATATGTGAGGAATGTGGTGAGTCGTTTAAAAGACGTCAACAGTTTCATGTTCATCTTGAGgttcataaaaagaaaaatttaaaattgcacaTACCTTCTGAAGACATTGAAAAACGGAAATCTTTCAAATGCAGTTTTTgtagtttagaatttaaaggatttaggtGGTATGAGAAGCATATTCAAGAAGGTCATAAGCTGGAAGGTTTTATATGTGAACATTGCGGAGCCCGGTTTAAGGAAAAGCTGAGTCTTCATCAACACAATTTTAAAGTTCATCGAAAAGAACTTCCATGTCCTCATTGcgataaaaaattcagtttcaaatCTAATTTGGACCGCCACATTGCACAACACACAGAATCAACAAAATCGTATATATGCGAGCAATGCGGTGCTAGTTATTACACTCCAATGTCGCTAAAGGAACATTTTACTTATGCTCACAAGGAAGTGAAGGAGTTTGTTTGTGAAACTTGTAATAAAGCCTTTTCGGCTAAGCGGGCTTGGCAACGACATCAAATTGTACATTCGGATGAAAGGCCATTCAATTGTAATTTATGTTCAAGAACTTTTAAGATTAAATCAAATCTTGTTCGACATAAACATCTCACACACAAACAAATTGCGCAACCTAATAAATTGAAGAGATTTGTTAAAAACGATAAAGGCGAATTAGTACCAGCGGAAGAAGATAATGTTGAGCCACCAAAcgataaattaaagaaaaaggaAATATCGAACAAAACAAATCTTAACAGTTATGCAACTCAACTTGGACCGCATAATAATGAAGCCATAATAAATGAGGGcaattttatgcaaattatgAACAATAATATGCAATACCAAGAATGTactaataatcaaaatattgaaatcatCCAAATCGGTCAAAATTACAATACATACACCGATAATcatatgaataataatattagtacTATGATTTTACAAGCAAATCAGAATCACGATGATTTTGGAAATGGTTATAACCAAACAGCGTACAACATGCAAGAGTGGAACAATGTGGATGCCCACAATCAAATCGAAGCTTATTCATTAGTTGAAGTTAATTCTGATTCGTTAATGTCATTGCATATGAAATCTTCAAATCGGAATGATAATCAGATAATGGATATATCAAATGTAGAATTATTGCATTATCCTGATATCTGGAGCACTACCGGTGCCACAAGTGTTAATAGTGGGGCAACAAATATAGAATATACAAATATCGATAATAGCCACCATCATCAgcaacagcagcagcaacaaccACATCAACATCCTAATTCGTATAATATTGGCAGCATTCTAACTAATCTTGAAATGATGgacaatcaaaataatattaacgaaataaatttaaatatgcaaaATTCTACCGGAACTTTGACAACATCTCACCTTAGTTACAATGATCCACATCATGtgcatcatcatcaccatcatcagcAGCATCACGATCAGCATTTGGATCAGTCACATTTGAATTATGATTTTAACAGTCAGAATCATACAATAACCGATATatcaaatacatttattaaagaAACGGATACTGATCGTTCCAATAATGAAAATCCTGGTGAAGAtgttaataattgtaataaaaataatatgatgATGTGCGCTTCAACGTCGAATGATGTAATCGAATCGATAGGACTCaattcaaaacaaatcaaagaaaTGCTACAGAATACTAACGAAAATGTAATGTTGCCTTCTCTGCTCGATTATTTGCAGCATCcgtatcaattttaa
Protein Sequence: MDESTHETILEANAAKCKIEELMAKLADLKVEFTKVENITTNIIEESVAGPSNVSQISNKENENMEKPKKKRERNRTKPKKGKFNEEIDITVEESPNELNVNLHLAQSKSKKKDKPVKNHVEAITDKSKMNANVCDPSITVTLTPETILIYKLLIMSPADRDKFIYKQAKERRILIRNIQTDLFEFNPIFYGGTAHQFIKPNDDNMNRKEKFPYHFEERRNKRSRKLKSRDEKSKSKQNKLYDLFETQVNRLLYGESKLTGQEKEEAIFLYNENGDKKNKLFSTEDNQINLEQFIQKLIDKDLGYIIESEIRINQKNNHEGYVTNNLNSEGDILVPSIVLRQCALHGDSVKVFAVKPNMYNGKEKAGNEVEDIKVISIDKDGGTENEDEDKDLCLAEVIDVPTPNKPRVLGFVLKIMEKVNTRQCIGTFKKISKTAASIFKPRDLKLPQIKINPIHMPESLLNQKDSSDEPDAAQNNVEEILYYVEIIDSSHHELIGRIIKPVGKCGELENENQAILLQNGLNPIQFSDDILKEIPAIPFMITDSEFSNRTDLRNQCIFTIDPPTARDLDDAVSSKILPNGNYEIGVHISDVSYFLKENSLIDEKIKNQTTSIYLVDKVYHMLPEKLCFLCSLTPGEDKLAFSVIWEITKTGEILKTEFKRTVINSCSQLSYDHAQAVIENSDKIFDEICFPHIYNNYKPSDLIEVVKQLNTIALVLRQQRFDNGALRINQPKLKFNLDHSSGKPISYYTERQQISNYLIEDFMLLANQSVAAFIFEKFPDLAVLRKHDSPNETALMKVTTKLSALNLRFDISNSKSIRESLEKLPKQCKSEEAGSSVLNFITAKQMTRAKYICSDQVTSIEELKHYALSIPIYTHFTSPIRRYPDILVHRLLCAGLNLDKVPERTTIELSKILKNCNQQKMDAKSAGDESANLYFIHYLKTVGSLKMRAAVLEIMEYSMEFIIMETGHILRIPYKVLTNSNEDTFILKYESIATSPSKRIKLEKDEDPISEDSEEFYDPICEEVNEVNVSQVKSKRRKRSPAESCDEQEPASKSKNFNCLQCGKIYRKKNSLITHSYHYHPGWCPTCGKYYGTTAKDLGDHNRKYHIKDYPHICEECGESFKRRQQFHVHLEVHKKKNLKLHIPSEDIEKRKSFKCSFCSLEFKGFRWYEKHIQEGHKLEGFICEHCGARFKEKLSLHQHNFKVHRKELPCPHCDKKFSFKSNLDRHIAQHTESTKSYICEQCGASYYTPMSLKEHFTYAHKEVKEFVCETCNKAFSAKRAWQRHQIVHSDERPFNCNLCSRTFKIKSNLVRHKHLTHKQIAQPNKLKRFVKNDKGELVPAEEDNVEPPNDKLKKKEISNKTNLNSYATQLGPHNNEAIINEGNFMQIMNNNMQYQECTNNQNIEIIQIGQNYNTYTDNHMNNNISTMILQANQNHDDFGNGYNQTAYNMQEWNNVDAHNQIEAYSLVEVNSDSLMSLHMKSSNRNDNQIMDISNVELLHYPDIWSTTGATSVNSGATNIEYTNIDNSHHHQQQQQQQPHQHPNSYNIGSILTNLEMMDNQNNINEINLNMQNSTGTLTTSHLSYNDPHHVHHHHHHQQHHDQHLDQSHLNYDFNSQNHTITDISNTFIKETDTDRSNNENPGEDVNNCNKNNMMMCASTSNDVIESIGLNSKQIKEMLQNTNENVMLPSLLDYLQHPYQF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01460709;
90% Identity: iTF_01460709;
80% Identity: -