Basic Information

Insect: Tipula helvola
Gene Symbol: ush
Assembly: GCA_963556165.1
Location: OY744482.1:31257290-31264223[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.013 4.8 10.6 0.1 1 20 246 265 246 267 0.92

2 9 0.00041 0.15 15.3 0.8 1 23 306 328 306 328 0.98

3 9 0.028 10 9.6 1.4 2 21 386 405 386 406 0.92

4 9 0.076 28 8.2 3.3 2 21 764 783 763 784 0.94

5 9 0.2 75 6.9 0.0 3 21 823 841 821 842 0.91

6 9 1.3e-05 0.0049 20.1 0.3 2 23 891 912 891 912 0.98

7 9 0.019 7 10.1 1.4 1 23 918 940 918 940 0.99

8 9 0.026 9.6 9.7 0.5 1 23 1004 1027 1004 1027 0.95

9 9 0.043 16 9.0 0.8 2 20 1158 1176 1157 1178 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.013	4.8	10.6	0.1	1	20	246	265	246	267	0.92
2	9	0.00041	0.15	15.3	0.8	1	23	306	328	306	328	0.98
3	9	0.028	10	9.6	1.4	2	21	386	405	386	406	0.92
4	9	0.076	28	8.2	3.3	2	21	764	783	763	784	0.94
5	9	0.2	75	6.9	0.0	3	21	823	841	821	842	0.91
6	9	1.3e-05	0.0049	20.1	0.3	2	23	891	912	891	912	0.98
7	9	0.019	7	10.1	1.4	1	23	918	940	918	940	0.99
8	9	0.026	9.6	9.7	0.5	1	23	1004	1027	1004	1027	0.95
9	9	0.043	16	9.0	0.8	2	20	1158	1176	1157	1178	0.93

Sequence Information

Coding Sequence: ATGAACTTACTAAACCGAGGTTTAAAGTTTGCACCGAAGCCATCACGAACTCCACTTGATGAAATCATAGTCAATCTTGAAAGCGGAGACGACGAAGATTTTGTCGAAGGTGCAACCACAACATCGTCCCAGCACCAAGATGATGTTGAATCACTTTCGGAAACGGCACAATCACGTACTCCATCACCAAATAATACTAATGTTACAACGCCCGTACAATCACCATCGATGTGCAGTAGCCCTGATCAGAATACACCACCGCCGCCGCCATCATCCGCATTCCTAGGCGGCGACCATAACGACGAGGGTAAAACACAAGATTATGAGTCGGGGCATGCGACTATCAAACAGGAGATGAAAATCGAGAATGATAGTCAGTCGAATGGTGGAAACGGTGGTGATGAGGAACAAGTCAATActagtaataacaataataataataataatactgcGGATAAACAGGTAGGCTCCGAGGCATTACCAAAACTTCGACTGAACACAATGTTGGCCTCGGACCCGGCATTAAAACCTGAAGCTAAAGATATTAAAGATCGGCGAGCGTCGACCGAGGATAATTCGAATGAGGATAAAAATGATGATGGATTTCATAATCATGCTGATCACGATATGGAGATTAAAGGAATTCGACTGATAAAAGAACGCTCAAACAATATTATTGTACCACCGCCAATAATAGCATCGCCCAGTTTAGACGCAGCACCACGAATGCAAGTTTTTATGTGTGGCCCCTGTGGTATACGATTTTCATCGCTGTCCACACTAGAAGCGCATCAAACCTATTATTGTTCGCATCGTAAAGATGCAGATGAAAATGTTGCACCGCAGAAACCATCGGCGAATAATGATAGTGGCGCATCAGAACCACcgaataaatcaataaaaacggGTAAACAGTACGCATGTACACAGTGCTCGTATAGTGCGGATAAAAAAGTCTCTCTAAATCGCCATATGCGAATGCACCAAACATCACCGGCTCCAAGTCCGAACACTACAAATGGTGGTTTGGTCGTGGTGAACGCCGGTAGTAGTTTACCAAACGCAGATGATACTCTTAACATTCCTAGTCAAATACAGCAACAGCAGTTGCAGCAGCAGCATCCACAACAAAATCAGGTACAACAAATTGATCGGTACTGTTCCGATTGTGATATTAGATTTTCGAGTACCAAAACATATCGCGCCCACAAGCAACACTATTGCAGTTCGAGGCATCGTGATGAaAATAGGTCGAATAGCACTACACCAAAACCGCCCTCAATTAAACGAGGGTCACACAGTCCACCAGATGCTCAACCAGTTGCAAAAAGTCCAGCTATTGTAAATCCGCCACCTAATCCAGTGCAGCCATATTTAGCGTTACCAACAAATCCTATTATAATAGTTCCATACACATTTATTCGGAATGCAAGTGTACTTACTGGGCCATTAGCATCGATTCCGACTAGTGTTACGAATCCCGAATCAACatgtttcattttccaaaatggtGCACTACAACCAATCGCCGTTGCACTATCACCACCAATTGCACAACCAACGCAACAAACTCCAACACAAAATGCCTCACCACGTGGGCCGACACCAAATCAAGCCACCTCCAATGAGAATAGTAATAACGCTAGTAATACTTCTGAAACGGTGTTAAAGGTGAGCAACAAACGTGATTTGACGGCCCGAGAATCGATGATTACAACTCCACTAGATTTATCGGTTCGCCGATTGTCGCCCGGATCAAATCCGCGTGAACGATCATTCTCATTCTCATCGATAGCCTCTCTCGAAAATCATCGTATCGACATCGATTCAATTATGGAAACAAAAGAGAATCTCTCAATGGGCGGCAGTGAATCGGTTACGCCCGAACAAATTGTTTGTGCACCATCATTACCCGGTAGTCCCCCGTTAACGCCATCACCAAAACGTCGATCGAATAGTCCACGCGGTGGAACCACATCTATATCACCAAATAATTCGTTGCCAAGTTCTGGTAGTAGCCAACAACACCAAGTAGTTATACGCTCGTTAATACCACCCGAATTAGCATTAAGGCTGTCCGAGCCATCAACCACATTAGCCGGCATGCCAAGCCATGCGTTAGCCAAACAAAATCTAGAATTATCACTGCGCCTCTCTTCGGCCGGCAGCAATAGTGAAATATCACCGCAGCCAACACCGCCACTAATTAGCATAATACCAAATCCAGCTACATCATCAAATGCATCGACCGCAATACCaccacaaatttttgttaaacagGGTGTCTCCAAGTGTAAAGAATGTAATATCGTATTTTGTAAGTACGAAAATTATTTAGCCCATAAAAAGCATTACTGTTCGGCACGCAATCTAGACGAAACGGAAAATAGTAAACCTAGTCCACCCGTATCACCGCAAGCGACCAGCCCCTCCGGAAGTGGAGCCCTAGCGTATCAACAATTAATTTGTGCTGCATGCGGTATTAAATTTACAGCGCTCGATAATTTGAGTGCTCACCAATTGTACTATTGTCCGAAGCGGGCCGAAATGTCAATGCCTATGGCCAAAGAATCACGTtgcaataaatgtaaaaatattcatGAGACTGGGGCACCGTGTCCGAATAATATAGGTGTTGGCGGCGGTAGCGGTACAAATCCATCGAATCGTAAATGTCCAATTTGTGATGTGGTTACGTCAACGTCGAATGAGTTGCGTAAACATATGGAAACGCATGGTGGAGTGAAGGCATTTCGGTGTACCATTTGTCGGTACAAGGGGAACACATTGCGtGGCATGAGAACACATATTCGAATGCATTTCGACAAGAAAACTtccgattttaatgaagaaAATTACATATCGTGCATTTTGGATGAAGATGGCATTGAAATTCCGGCACAACCGCTTTTAGCTATTTCACAGGCACCTCCGGTGATAccgccaccaccaccaccaccgtCGCTCTCTATGCCCATCTTACAGGACCCGATTTCATCACAACAAATTCATTATTGCGATTTGTGCAACTACTCATCTAGCATTAAGGGGAATGTgATTCGACATATAAATTTAGTGCACGCAAGTAATCGACCACCTCTATCGCCGTCACTCGGTGAAGGTGGTGAAAGTTTATTGTTCAATGGAGATTTGCAAACATCGCCGGCCCAGCTACAATTCAATTCGGCTAAAACAGCACAACCAACAAACAAGCTAATGAATGaAATTTCTGTCAAACAAGAACCACTAGACGAACCACAACTCATTGAAGATTCGCGTGACACTATCATATCAACAGAATCTGAAATACTAATTAAAACCGAAATCAAAGATACAATTGATACAAATACAACGATGCCAATAATGTCACCACTAATTCAAACGATAACGCAAccactacaacaacaacaacaacagcattCGGCTAGTTCATCGCCCGATTTACAATCGTTAACGACAGCGGGtccaaaatattgtaaacagtgtgacataaaatttaattatctcaGCACGTTTATTGCGCACAAACAATTCTATTGCAAAAGTGGTATAAGCGTGGGCGTGGAACGTGAAAATACAGGTTCGAGTCCTACACAATCGGCAAATAACAATGTTGTTACACGTGCAACCGAAGCAtcggttttgtaa
Protein Sequence: MNLLNRGLKFAPKPSRTPLDEIIVNLESGDDEDFVEGATTTSSQHQDDVESLSETAQSRTPSPNNTNVTTPVQSPSMCSSPDQNTPPPPPSSAFLGGDHNDEGKTQDYESGHATIKQEMKIENDSQSNGGNGGDEEQVNTSNNNNNNNNTADKQVGSEALPKLRLNTMLASDPALKPEAKDIKDRRASTEDNSNEDKNDDGFHNHADHDMEIKGIRLIKERSNNIIVPPPIIASPSLDAAPRMQVFMCGPCGIRFSSLSTLEAHQTYYCSHRKDADENVAPQKPSANNDSGASEPPNKSIKTGKQYACTQCSYSADKKVSLNRHMRMHQTSPAPSPNTTNGGLVVVNAGSSLPNADDTLNIPSQIQQQQLQQQHPQQNQVQQIDRYCSDCDIRFSSTKTYRAHKQHYCSSRHRDENRSNSTTPKPPSIKRGSHSPPDAQPVAKSPAIVNPPPNPVQPYLALPTNPIIIVPYTFIRNASVLTGPLASIPTSVTNPESTCFIFQNGALQPIAVALSPPIAQPTQQTPTQNASPRGPTPNQATSNENSNNASNTSETVLKVSNKRDLTARESMITTPLDLSVRRLSPGSNPRERSFSFSSIASLENHRIDIDSIMETKENLSMGGSESVTPEQIVCAPSLPGSPPLTPSPKRRSNSPRGGTTSISPNNSLPSSGSSQQHQVVIRSLIPPELALRLSEPSTTLAGMPSHALAKQNLELSLRLSSAGSNSEISPQPTPPLISIIPNPATSSNASTAIPPQIFVKQGVSKCKECNIVFCKYENYLAHKKHYCSARNLDETENSKPSPPVSPQATSPSGSGALAYQQLICAACGIKFTALDNLSAHQLYYCPKRAEMSMPMAKESRCNKCKNIHETGAPCPNNIGVGGGSGTNPSNRKCPICDVVTSTSNELRKHMETHGGVKAFRCTICRYKGNTLRGMRTHIRMHFDKKTSDFNEENYISCILDEDGIEIPAQPLLAISQAPPVIPPPPPPPSLSMPILQDPISSQQIHYCDLCNYSSSIKGNVIRHINLVHASNRPPLSPSLGEGGESLLFNGDLQTSPAQLQFNSAKTAQPTNKLMNEISVKQEPLDEPQLIEDSRDTIISTESEILIKTEIKDTIDTNTTMPIMSPLIQTITQPLQQQQQQHSASSSPDLQSLTTAGPKYCKQCDIKFNYLSTFIAHKQFYCKSGISVGVERENTGSSPTQSANNNVVTRATEASVL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01459054; iTF_01053890; iTF_01052750; iTF_01457940; iTF_01054806; iTF_01460702;
90% Identity: iTF_01460702;
80% Identity: -