Thel056065.1
Basic Information
- Insect
- Tipula helvola
- Gene Symbol
- thap1
- Assembly
- GCA_963556165.1
- Location
- OY744482.1:98621177-98626389[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 9.9 3.7e+03 1.5 0.1 5 16 168 179 167 181 0.82 2 12 0.015 5.7 10.4 0.9 2 23 338 360 337 360 0.94 3 12 0.077 29 8.2 0.7 2 23 366 388 365 388 0.92 4 12 0.026 9.5 9.7 0.5 1 21 419 439 419 440 0.94 5 12 1.2 4.4e+02 4.5 1.5 2 21 448 467 447 468 0.93 6 12 0.0004 0.15 15.4 3.2 1 23 495 517 495 517 0.98 7 12 0.21 78 6.8 0.7 2 19 526 543 525 546 0.93 8 12 0.0045 1.7 12.1 0.7 1 23 575 597 575 597 0.96 9 12 1.9e-06 0.0007 22.7 1.4 1 23 603 625 603 625 0.98 10 12 0.00055 0.2 14.9 1.9 1 23 631 654 631 654 0.96 11 12 0.26 98 6.5 0.1 1 16 660 675 660 677 0.85 12 12 5.3 2e+03 2.4 0.0 3 13 817 827 816 828 0.88
Sequence Information
- Coding Sequence
- atgccCTCGACATGTATAATTCGAGgctgtaaaacaaaatatgcgACAGACGTATCGTTTCACAAATTCCCAGTTAAAAATACTAAACTACTTGGTGAATGGATAAAATTTGCGAACCGTGGTGAAAATTGGAAACCCACCCGATGGACTTCGATTTGTAGTTCACATTTCCAACGGTCTGATTTTCAGGATCGTATTAATCAacgtaaaacattaaaaaaatttgctgtgCCATCGATTAATGAGGGCACCGTAGACGATATATATCAGGTGAATAATGATTCCGGTGGTGAGGCATCGACAAATGATTATGCGGAGACAACAATGCTACCGCCACGTTCATCAGTATTGTACAATACGTACGTGGAACCGTTGTGCCATTTCTGTGGCGACAAATCTagcgtttttaatttttccaaattgaaTTTAACTCATTTCAATGCCATCATTAAAATGTATCCTTACCTCAATTTAAATGAGTACAAtgagaatttgataaaaatctgTGATAAGTGTTACAATACGATTGCAAATTTTGAAGTGTTGTTAACCAATTTCTTGAAATTGCATGGTTGTGGCGATGATGTGGACCATCCCATTGATTCTCCAGAACTTGGAGATGATACGTACAAAGATACCATTAAACTGCAGAAGGTGAAAATAAAACAGGAACCCGTAACGGTTATAAAAGAAGAGATTTTAGAGCCGGGTCAGAGATTTATACCGTCTGAACTGCTAACGGGGCAATCACTAAGTAATAACGATGTTATTGAGGTTACACCACCCAACGACATTATAAACATTATCGAAGAGGATAACATCGGGAATATTCAAGAGGAATTCGATTTCGAATTAAAGTCTGAAGAGGCCGTTAAAATCGAAGTGGTCGATGTTAATGAGCTGCGCGATCTTGGAAATGCTATGCACGATCATTCGTATTCTAAATGCACTGGGGAGAACCGGTACGAGTATGATAATGATGAACAGAAACCGTTTCTTTTCGATCAGATTACTTGCACACTTTGCAATTCGTATTTTGAGGATAAACAGCAGCTGGAAAAACATACCAGCATATTCCATACGTTTCACAGTCAAACTTGTAATGAATGCtatctagaatttaaaactCTGTACGATTATTTGATTCACAAGAATGATACCCATGGCAAAATTAAACCGATTACCGAAGGTGCTGAACAAGAACCCACCGTCGTATATGACAGTACACCCACCAAACAATCGAATGAGCTAAAATTTATCTGTGATTTGTGTAACGAAGCTCTAGCCACAAAAACGTCGCTCAATCATCACAAAAAGTATCTGTGCCAGTTTAAGTTGCAGTACTGTAAAGTGTGTAAAATCGGATTCGAGAATCTGGAAGTATTTCGAACGCATATATGCCATAAAAAAGCGATGCATCGAAGCGGCGCAAACTTGGTACGAAATAAAACTGCcaagttaaattttatgaaaaatggtCGATACACATGTAAATTCTGTTCACGAACCTATGGCAAATACTATAATCTACTCAAGCATATACGCCTACATCGCCCGATCCAGGaatggaatttaaaatgtggCAATTGTGGTATGCTATTTGATCGGATCTATGACCTAAATCAACATTGCCGCCGTAGTATATGCACAATAAATCCTAATGAACCggtaattccaaaattcaattataattcGTCCGGATATAAACGCCAAAAGCTAAAATACGTATGCCTCAAGTGTAATAAGATTTTGTCATCGAGTAAAAGTCTCAAGCTGCATGAGTATATTCATAGTACGACACGACCCTTTGTGTGTGAAACGTGCGGCAAAAAATTTCGAAGTCCAATCAATTTGAGGCAACACAAAAAATCGCATGTTGATCAAAAACAGTTTGCCTGTAGTTACTGTGACAAGAAATTCAagtggaaaacaaatttaaggtTGCACGTGAATTCATATCATTTGAATATAAAACCACATGCTTGTCCCCATTGTAATTATCGGTATGCTAGAAGGCGAGAAATGTTAAGGTCCGATGAGATCGAGGCAGAGTCACGGAAATGTGCGATTTTCCTCACAGTTTCCGGACCGCAACTCTTTGATCTCCTCGTCTCATTGGCATCACCTAAAGAGGTAAGTACTGTTACCctagaagaaattaaagatactctaaaaaatcatttctctTCCAAACCATCTGAAATTGCGGCGTTCTTCACATTTTTTAAACGGGACCAATTACCGGACGAACTGTTTGCCTCGTATGTTGCTGAATTACGTCGATTGGCTGTAGATTATGAAGGACTGCAACGAAACTTTCTAGCCAATGTAGGGCTGAACCTGACCCAGGTTATCAATCGAGCTCAAACAGCTGAAGGAGTAACAAAAAATCTCCATGATATTCGTTATCCGAAAAAAGTTCAGCAAAAACAATCTACAATTCGACCTTGTAATGGATGTGGTGTATCATATGCTCGTTCGTTATGCCCGCATTTAAATGCCGTATGCAATTCTTGCGGTAAAACCCAAAGTGTATGTCGATCTTCTGCTAAAACAACACCGATCAACAAAAGGAACAAGCACAATCGTAACCAATCGAAATCGAAAATTAACCAAATATTGCCATTGGTTGATTGGAAAAAGAGGACAACCATTGTCATCAACGATAAGCCATGTGGTTTCGAAGTCGATTCAGGGTCAAACTATACGATCATAtcgttcaacatttttaaattgatttggcCGTCCACTCATCCTGAGATTTCAAAATACGATAGTGACCCACAAGAGAGCTTTCCGAGTTCCCAAATTACAATTCGGAATCTCATCTGCTCCtggaatattccaaaatttcatcgaGGGATTGCTCAACTGGCTGAGCGATTAACCGAAATTTTATCCAGAATTGACAAGAATGGCCTTCGTCTTAAgctaacaaaatgtaaatttggagcACCAACCATCAATTTTCTCGGTTACAAAATCGACGGACTTGGAATTCGTCCAACCACGGAAAAGGTACACGCCAACACAAATGCATCACCACCGATTGACAAGAAACAATTACAAGCGTTCTTGGGCCTTCTGAATTATTACCACACTTTTCTACCGCAAAAGGCAACCGTCGCCAAACCATTGCATCGTCTTCTAGATCAGAACCAAAAGTGGGAATGGACTAAAATTCATCAAGAGGCATTCGATGATCTAAAAAACATGTTAGCGTCCGACCAAGTTTTGATACACTATAACGAGAAACTACCTCTCTTGTTAGTATGTGATGCCTCGCCGTATGGTCAAAAGCTCAGCGAATCAGTAGTTAATACACGAATTTGTATTTGGTCGACATTTCACAATTGTCACCGATCACCGACCACTCTTGGGAATATTTAA
- Protein Sequence
- MPSTCIIRGCKTKYATDVSFHKFPVKNTKLLGEWIKFANRGENWKPTRWTSICSSHFQRSDFQDRINQRKTLKKFAVPSINEGTVDDIYQVNNDSGGEASTNDYAETTMLPPRSSVLYNTYVEPLCHFCGDKSSVFNFSKLNLTHFNAIIKMYPYLNLNEYNENLIKICDKCYNTIANFEVLLTNFLKLHGCGDDVDHPIDSPELGDDTYKDTIKLQKVKIKQEPVTVIKEEILEPGQRFIPSELLTGQSLSNNDVIEVTPPNDIINIIEEDNIGNIQEEFDFELKSEEAVKIEVVDVNELRDLGNAMHDHSYSKCTGENRYEYDNDEQKPFLFDQITCTLCNSYFEDKQQLEKHTSIFHTFHSQTCNECYLEFKTLYDYLIHKNDTHGKIKPITEGAEQEPTVVYDSTPTKQSNELKFICDLCNEALATKTSLNHHKKYLCQFKLQYCKVCKIGFENLEVFRTHICHKKAMHRSGANLVRNKTAKLNFMKNGRYTCKFCSRTYGKYYNLLKHIRLHRPIQEWNLKCGNCGMLFDRIYDLNQHCRRSICTINPNEPVIPKFNYNSSGYKRQKLKYVCLKCNKILSSSKSLKLHEYIHSTTRPFVCETCGKKFRSPINLRQHKKSHVDQKQFACSYCDKKFKWKTNLRLHVNSYHLNIKPHACPHCNYRYARRREMLRSDEIEAESRKCAIFLTVSGPQLFDLLVSLASPKEVSTVTLEEIKDTLKNHFSSKPSEIAAFFTFFKRDQLPDELFASYVAELRRLAVDYEGLQRNFLANVGLNLTQVINRAQTAEGVTKNLHDIRYPKKVQQKQSTIRPCNGCGVSYARSLCPHLNAVCNSCGKTQSVCRSSAKTTPINKRNKHNRNQSKSKINQILPLVDWKKRTTIVINDKPCGFEVDSGSNYTIISFNIFKLIWPSTHPEISKYDSDPQESFPSSQITIRNLICSWNIPKFHRGIAQLAERLTEILSRIDKNGLRLKLTKCKFGAPTINFLGYKIDGLGIRPTTEKVHANTNASPPIDKKQLQAFLGLLNYYHTFLPQKATVAKPLHRLLDQNQKWEWTKIHQEAFDDLKNMLASDQVLIHYNEKLPLLLVCDASPYGQKLSESVVNTRICIWSTFHNCHRSPTTLGNI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -