Basic Information

Insect: Tipula helvola
Gene Symbol: -
Assembly: GCA_963556165.1
Location: OY744483.1:143739822-143741669[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.23 87 6.7 5.1 1 23 232 254 232 254 0.98

2 11 0.0047 1.8 12.0 1.6 1 21 260 280 260 281 0.95

3 11 0.045 17 8.9 5.9 3 23 290 310 289 310 0.97

4 11 0.016 5.9 10.4 7.1 1 23 316 338 316 338 0.97

5 11 0.00013 0.05 16.9 1.3 2 22 344 364 343 366 0.89

6 11 0.64 2.4e+02 5.3 2.9 2 21 395 414 394 417 0.88

7 11 0.014 5.2 10.5 4.2 1 23 423 445 423 445 0.96

8 11 9.8e-06 0.0036 20.5 1.0 1 23 464 486 464 486 0.96

9 11 6.5e-05 0.024 17.9 2.0 1 23 492 515 492 515 0.96

10 11 0.00049 0.18 15.1 0.1 1 23 523 545 523 545 0.98

11 11 0.0035 1.3 12.4 6.5 1 23 551 574 551 574 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.23	87	6.7	5.1	1	23	232	254	232	254	0.98
2	11	0.0047	1.8	12.0	1.6	1	21	260	280	260	281	0.95
3	11	0.045	17	8.9	5.9	3	23	290	310	289	310	0.97
4	11	0.016	5.9	10.4	7.1	1	23	316	338	316	338	0.97
5	11	0.00013	0.05	16.9	1.3	2	22	344	364	343	366	0.89
6	11	0.64	2.4e+02	5.3	2.9	2	21	395	414	394	417	0.88
7	11	0.014	5.2	10.5	4.2	1	23	423	445	423	445	0.96
8	11	9.8e-06	0.0036	20.5	1.0	1	23	464	486	464	486	0.96
9	11	6.5e-05	0.024	17.9	2.0	1	23	492	515	492	515	0.96
10	11	0.00049	0.18	15.1	0.1	1	23	523	545	523	545	0.98
11	11	0.0035	1.3	12.4	6.5	1	23	551	574	551	574	0.96

Sequence Information

Coding Sequence: ATGAAGAATACCGTCCcagaatattatttaaatgatccaGACATACGATGTGAAGCTGATTTGCCATCTATAAAAGTGGAATGTGATAATTTCATTAGTTCACAACCCTTAAATGATTCCTTATCGGTGCCAGAGGAGTTTGAGCCAGTTatcgcaataaataaaaaagataatGAAGGAGCTTCATCACTAAATGAAAATGCAACTAAATGTTTTCAGACAAATTGTAACGAGAGGTTCGctaaaatgatgaaatattataaggatgaaattaaatttctccGAAGCGAAGTTACACAGCTCCAGAAATATAAATCGGAAAACTCATCGATTAATAATTCATTGCCAAATTTAAGTTCAGCGGCGAAGGAGTTTGGCAAAATGATTTTGAACGATTCGACAAGGGTTTGGCCCTGCTTAAAATGTATGGAAGATATACAAGCCGCgatgaaattaaagaaaaatattgatgATAAGAAGAAATTGGAAGTAAAAAAGTTAATCGAAGAACCAAAACTGAATCTCGAATTGgaccataataaaaatttcgatattaatGTAGAAATGGTGATGTTAACTGCTGGACAAATCGAAGAAAGTCCGAGAGATCTAGATCCAGTAGACATGAAATCTAAGAATGATGAAGAGGACGAACCGCTGGTCGAACAATCCATGGGATTAAGCCCAGACCAATACGAATGCGAAAAATGCCGAGAAAAACACAAAACCTACAAACAGTTAATATATCATATGAGATTTCATAAAGATATAAACATGTATGAGTGTGAAAGATGTGGTAAAGAGTTTCATCATGGTTCGAAATATCGCAATCATGCTCGTATTTACAAATCAGAAAAACCTGCAATATGCAAGATTTGTAAAAAAGGATTTAAATGTTCAAATCATCTGAGACAACATGAATTAACTcacaaaactgaaaaaatacaTAAGTGTCCATATTGCAGTAAATGGTTTTGTCATAAGAAAGGATTGAACCAACATTTAATTAATCACAAAGAAAAACATATTAAATGCACGAAGtgtgacaaaaaatttcaatacaaaagCCAGTTAAGAATACATAATGAGTTAGTTCATGAACCAAAAGAAGCCAGAGAGAGAAGCAATAAAACAATCAAGCACGTTAATCAACCAATCAATAAAACGTTACAAAAGCAATGTGCTTGCGAAAAATGTGGGAAATTGTTTGCTACTGAGATTAGTTTGAAATTCCATATCAAATGTATTCATAACAGGATAAGGCCGTTTCCATGTGCCTATTGTAATAAATCGTTTAGCATATCGACGTCTTTAAATTGTCACATTCAACAtcatattaattcaaaaaaccCTAAAATGGATCCTAAAACAATAGAatcatatttgaaatataagtGTGACGAGTGTGACAAGGCGTTTACaacttcgatttttttgaaaaatcacaaaatattgcATTCAGGTTCAAAAGATCATGTCTGTACACATTGTGGAAAAGGATTTGCATTTAaatggtatttagatcgccACGTTCGTTTAGTTCATGATACGACGCACCCAAGGAATTTTGTTTGTAGTATTTGTCGCAAGGTATCTGCAAATATATGGGCTTTGAAATCACACATGCTATCGCACACTGGTGAGACACCGTTCCATTGTAAATTTTGTGATTCTAAATTCAGATATAAAAAATCTCTTCGAATCCATATGAACAACAAACATAcctaa
Protein Sequence: MKNTVPEYYLNDPDIRCEADLPSIKVECDNFISSQPLNDSLSVPEEFEPVIAINKKDNEGASSLNENATKCFQTNCNERFAKMMKYYKDEIKFLRSEVTQLQKYKSENSSINNSLPNLSSAAKEFGKMILNDSTRVWPCLKCMEDIQAAMKLKKNIDDKKKLEVKKLIEEPKLNLELDHNKNFDINVEMVMLTAGQIEESPRDLDPVDMKSKNDEEDEPLVEQSMGLSPDQYECEKCREKHKTYKQLIYHMRFHKDINMYECERCGKEFHHGSKYRNHARIYKSEKPAICKICKKGFKCSNHLRQHELTHKTEKIHKCPYCSKWFCHKKGLNQHLINHKEKHIKCTKCDKKFQYKSQLRIHNELVHEPKEARERSNKTIKHVNQPINKTLQKQCACEKCGKLFATEISLKFHIKCIHNRIRPFPCAYCNKSFSISTSLNCHIQHHINSKNPKMDPKTIESYLKYKCDECDKAFTTSIFLKNHKILHSGSKDHVCTHCGKGFAFKWYLDRHVRLVHDTTHPRNFVCSICRKVSANIWALKSHMLSHTGETPFHCKFCDSKFRYKKSLRIHMNNKHT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -