Basic Information

Insect: Tipula helvola
Gene Symbol: ZFX
Assembly: GCA_963556165.1
Location: OY744481.1:270714944-270716078[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00056 0.21 14.9 2.0 2 23 132 154 131 154 0.97

2 8 2.6e-05 0.0096 19.1 1.5 1 23 162 185 162 185 0.96

3 8 4.7e-06 0.0017 21.5 3.8 3 23 194 214 192 214 0.97

4 8 6.4e-05 0.024 17.9 1.2 1 23 220 242 220 242 0.99

5 8 1.1e-06 0.00042 23.4 0.5 1 23 248 270 248 270 0.98

6 8 0.52 1.9e+02 5.6 1.1 1 23 276 298 276 298 0.95

7 8 0.00054 0.2 15.0 4.6 2 23 305 326 304 326 0.96

8 8 4e-05 0.015 18.5 5.3 1 23 332 355 332 355 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00056	0.21	14.9	2.0	2	23	132	154	131	154	0.97
2	8	2.6e-05	0.0096	19.1	1.5	1	23	162	185	162	185	0.96
3	8	4.7e-06	0.0017	21.5	3.8	3	23	194	214	192	214	0.97
4	8	6.4e-05	0.024	17.9	1.2	1	23	220	242	220	242	0.99
5	8	1.1e-06	0.00042	23.4	0.5	1	23	248	270	248	270	0.98
6	8	0.52	1.9e+02	5.6	1.1	1	23	276	298	276	298	0.95
7	8	0.00054	0.2	15.0	4.6	2	23	305	326	304	326	0.96
8	8	4e-05	0.015	18.5	5.3	1	23	332	355	332	355	0.95

Sequence Information

Coding Sequence: ATGGATCAGAAAATGTGTCGAACTTGTTTGGGCGAAACAAATGGATCAATTTTTACAACTGTAATTCTGGCACACAAAGAATTATCATTGGTTGAAATGCTTAACGAATGTACGGAATTAAAGGTGACCGAATTTGACGAGATATCTTTAAATATTTGCGATATTTGTACAGAAGAAATAATACGCTCTTACGAGTTCCGGAAAAAATGTTGGGAGTCGCACAGTTTTCTGGTACGACGACTGGATGAAAGCAGAAATGACAGAGATCCATTAAAATTTGAAGCGCCAAGTTCTGTAGAACCAGTTGATGAGGTAGCTGATTTGTTTGAGGTAGCAGATTTAGAAGAGAAAGTTGTTCCAATGAAAAATCAAACACCTGATAGAGGTGCTGTAAAGTGTGATTTGTGCGATAAGATCTACTTTCGTAGGAAATTAATGGTGCACCATTTGCGTACGGAGCATAATATTCTAGAATTGCATAAATATGAGTGTCAATACTGTAAAAAATCATTCGATTACTTTAGTAACGCGAAGCGGCATATTATCAATATTCATGAACAGGACGAAGGGAAAGTTATATGCCATCACTGtggtgaaaatttaaaaaatcggacAAATTTGATACGGCATATGCGACGACACACTGGTGAAAAAccatttaaatgtaatttctgTGAATATAGCGCAACGCAACTAGCCACTCTTACTAACCATTTGCGAACACATACAGGTGAGCGGCCTTATGAATGCGATATTTGCGGCAAAGTATTTCGATCTTCTAGTTCACGTGCGAGTCATCGTAAAGTCCATTCCACAGAAACCCCATACGAGTGCattgtttgtttgaaaaaatttaaacttaaaagaatttttaaggAACATATGAACATTCATGACCCGGACAAGTATATcgaatgtaaatattgttgcaaacaattttcgcggaaaaaaaatttaatggtgCACTTGAAACAGCACACTGGCCAAAAACCGCATATATGTGAAGTCTGCGGCAAAGGATTTATACAAAAACATTGTTTGCGCAATCACATGAATAATTATCATAatcaataa
Protein Sequence: MDQKMCRTCLGETNGSIFTTVILAHKELSLVEMLNECTELKVTEFDEISLNICDICTEEIIRSYEFRKKCWESHSFLVRRLDESRNDRDPLKFEAPSSVEPVDEVADLFEVADLEEKVVPMKNQTPDRGAVKCDLCDKIYFRRKLMVHHLRTEHNILELHKYECQYCKKSFDYFSNAKRHIINIHEQDEGKVICHHCGENLKNRTNLIRHMRRHTGEKPFKCNFCEYSATQLATLTNHLRTHTGERPYECDICGKVFRSSSSRASHRKVHSTETPYECIVCLKKFKLKRIFKEHMNIHDPDKYIECKYCCKQFSRKKNLMVHLKQHTGQKPHICEVCGKGFIQKHCLRNHMNNYHNQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01460399;
90% Identity: iTF_01456571;
80% Identity: iTF_01456571;