Thel040949.1
Basic Information
- Insect
- Tipula helvola
- Gene Symbol
- -
- Assembly
- GCA_963556165.1
- Location
- OY744481.1:345767951-345769228[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.012 4.3 10.8 0.5 1 22 130 151 130 151 0.94 2 8 0.0041 1.5 12.2 0.8 3 23 162 183 161 183 0.95 3 8 0.0015 0.56 13.6 0.7 1 20 191 210 191 212 0.95 4 8 1.5e-06 0.00055 23.0 0.9 1 23 226 248 226 248 0.98 5 8 0.00087 0.33 14.3 3.7 3 23 254 274 253 274 0.98 6 8 2.5e-06 0.00092 22.3 3.1 1 23 280 302 280 302 0.98 7 8 9.2e-07 0.00034 23.7 0.9 1 23 308 330 308 330 0.98 8 8 5.2e-05 0.019 18.2 0.5 1 23 336 360 336 360 0.96
Sequence Information
- Coding Sequence
- ATGTCAAAAATACAACGGACTAAGGTTAATAGTGAAGCATCCCCTCCAACAAAACGAGTTCGATTACGCAGACTAAGCGAAttggttaaatataaaaatgagcTAAAAAGCTTGAATAAACCTAACTTGGGATCAGTATCGGAAATTTATGATAAGTTGAAAGCCAAAAGTAATTTAACCATTTCAAAATTCGTTGAGTCTGAAGATGAAGAGGATGAGAAGGAAGATTCCGATAGCGACGGTGATTATTCGGTCCCGCCTGAAATGCCCGTGGACCTAACATCCGATAGTGATTGGTCAGATAATGAAAAGGGAGGTGTGACTAAACGTAAACGGAATGTGGTTAAAAATCCAAGAATTATATCGTTAGAACATATGCAGCCCAATTTCGTGTGTGCCCGTTGCAAGGGCAAATTTAAATCGCTGGAAGCATTACGCCATCATCTTGAAACCAATAACGAATGTAAAGATACTGATATACTTTGTGGTgaatgcaaaaaaatattcaaaaccagACGGGTCTATTCCAAGCATGTTCGTGATGTGCACGAGAAAAAAGAATCACCCATATTCAAGTGTACCAATTGTGAAGAGATTTTCCCGCGCGAATGTGAGCTCCAAAATCATCGAGTGATGTGTACCGGAGTATGTAACGAGGATTTTTCagggattttatttaaatgcaaGGACTGCGACAAAAGTTTTGAGAAACGAATTGATTTAGTAAAACACATTGAAAACCATACGAAACAACTTCTTTGCGAAACGTGTGGCAAATCATGTAAAACCAAAAAGGCATACAGCCAGCACACTCGAGAACATTTAGGACTGAAACCATTTAAATGCACGTTGTGCGAAAAAAGCTTTCGAACAAATACTCTGCTTCAGGCCCACCAGCATGTACACACCGGAATTAAAACATACGTTTGCGATACATGTGGAAAAACATTTGCCAAACGAGCTTCTCTAATTCATCATGTTCGACTGCATACCGGTGAGAAACCGTATGCTTGTGATTTATGGATGTGTGAGGAGCGATTCTCGACTTCGGAtcgtttaaaaaatcatttgcgGAAGCATCGCCAAAATTTTTATGTAGAATAG
- Protein Sequence
- MSKIQRTKVNSEASPPTKRVRLRRLSELVKYKNELKSLNKPNLGSVSEIYDKLKAKSNLTISKFVESEDEEDEKEDSDSDGDYSVPPEMPVDLTSDSDWSDNEKGGVTKRKRNVVKNPRIISLEHMQPNFVCARCKGKFKSLEALRHHLETNNECKDTDILCGECKKIFKTRRVYSKHVRDVHEKKESPIFKCTNCEEIFPRECELQNHRVMCTGVCNEDFSGILFKCKDCDKSFEKRIDLVKHIENHTKQLLCETCGKSCKTKKAYSQHTREHLGLKPFKCTLCEKSFRTNTLLQAHQHVHTGIKTYVCDTCGKTFAKRASLIHHVRLHTGEKPYACDLWMCEERFSTSDRLKNHLRKHRQNFYVE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01460646; iTF_01458992;
- 90% Identity
- iTF_01460646;
- 80% Identity
- -