Thel101829.1
Basic Information
- Insect
- Tipula helvola
- Gene Symbol
- K02A2.6
- Assembly
- GCA_963556165.1
- Location
- OY744483.1:143744570-143748231[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 6.4e-05 0.024 17.9 1.4 1 23 115 137 115 137 0.98 2 11 6.9 2.6e+03 2.0 7.7 1 19 143 161 143 165 0.90 3 11 8e-05 0.03 17.6 0.2 1 23 171 193 171 193 0.96 4 11 0.15 54 7.3 2.9 2 20 200 218 199 220 0.93 5 11 8.4e-06 0.0031 20.7 0.2 3 23 228 249 226 249 0.95 6 11 0.0078 2.9 11.3 0.1 1 23 274 297 274 297 0.96 7 11 0.0021 0.79 13.1 6.3 1 23 303 325 303 325 0.97 8 11 1.3e-05 0.005 20.0 0.7 1 23 344 366 344 366 0.98 9 11 6.5e-05 0.024 17.9 0.7 1 23 372 395 372 395 0.96 10 11 0.0014 0.52 13.7 0.6 3 23 405 425 403 425 0.96 11 11 0.099 37 7.8 3.0 1 19 431 449 431 450 0.96
Sequence Information
- Coding Sequence
- ATGTGTTTAGCGGCGAAGGAATTTGGTAATATGGTTTTGAACGATCCAACAAGAGATTGGCCCTGTATAAAATGTATGGAAGATATAAAAATCGCCTTTAAATCAAAGGAAGATAATATAACGTCAGATGATACGATTACATTGGAAATTAATAACACAGTTGAAGATTCAATATCAAATTTAGCATCTGGAGATGAAAGAAATTCTGATAGAGAACAGGCGAATTTAATTGCTGACAAATTCGAAAAaagTTCGGTAGACCTAGATTCAGGAGCAAAGAAGTCTGAAAATCGTGGTGAGGGCCAGGTGTCGATTGAACAATCTATTGCAACTCCTGCCTTGTATGAATGTGAAAAATGCAAcatgaaatttattacatacaAAGGGTTAATCAATCATATGAGATTTCATCCAGATATAAATTTATTCGAGTGCGAAAGATGTGGTAAAGAATTTCATACTGTTTCGAGATACCACCGCCATTGCTATAGTCACGCAACAGATACACCTTTTATATGTCAGATTTGTAATAAGGGTTTTAAAAGTCCGATTCTTTTGAAACAACATGAGTTAATTCACCAAAAGGTTAAAATACTTCCCTGTCCGCATTGTGATAAATGGTTTTGTCATGACAAAGCATTAAAGCAACACttaagttttattaaagaaaaaaaaatagcatGTACTATGTGTGataaaaaatttcgatataATAGCCTCTTAAAAGTACATATGGATATAGCTCATGAACTAGGAGTCAACCAAGGAAGTGAAACAATCGGACACATTAGAACCGTTAAAAAGAcgttacaaaaacaatttgctTGTGAAAAATGTGGAAAATTACTCGCAACCGAGTTTGGTTTAAGAGCGCATATCAGTCGTAAACATAATATGGAAAGGCCATTTCAATGTTCATATTGTAGTAAATCGTTTAGCACAGCTACGTCTTTACAATGTCACATTCAACAtcatattaattcaaaaaaccCTAAAATGGATCCTAAAACAATAGAatcatatttgaaatataagtGTGATGAGTGTGACAGAGCGTTTACAAATTCGGTGTTTTTGAagaatcacaaaataatacattCAGGTTCGAAAGATCACGTTTGTACACAATGTGGAAAAGGATTTGCATTTAAGTGGTATTTAGTTCGCCACGTGCGTTTAGTTCATGATACGACGTACCCAACCAATATTATATGTAGTATTTGTCGCAAAGTATCGTCAAGTACGCACGCTTTAGAATCACATATGCTATCGCACACTGGTGAGACACCATTTCATTGTACATTTTGTGATTCTAAATTCCGATATAAAAAATCACTTCGAATACATgcgGGCTTCTGCAGCAGTTCACGCATTTGGAGACAGCTCCAACAAAAACGACGAAATGATCCGGGCCGTCGCAGCAATGCGATCAGCACTACTCATCCAAATTCAACCATAAAGTTTGTCACGGCAACAGTTGACGGAACGAAAGTCAAACTGCAGCATGATAGTGGGTCAGACTTGACGATCATATCTCAAGCGAACTGGATGAAACTCGGCGAACGAAACTTGAGGCGCCACAAAGGAACTGCCGTAAACGCTTCCGGCAAACCTATAAGCATCCTGGGATGTTTTGACGCAACTTTGAAGATAGGCAACCACGAGGCTACTGGAATCATCTACGTCTCACCTTCAATGCTGAATCTTTTTGCCAACGAATGGATGACAAAACTCAAATTGTGGGATGTACCACCGTCAGCATACTGCCATAATGTCAACGCAGTACACAGCGGTCCACACCCCCTCGAAAACGAGATAGAAGCAAAGTTCCCTATGCTCTTCTCCGAAACCTTAGGCcggtgcaataaaataaaagcatcACTGACGCTGAAGCCAGGGGCAAACCCGATCTTTCGCCGTGCACGGCCGGTGCCACATGCAGCCGCGAAACCAATCGAGGACGAACTTATTCGCCTACAGTGCCAATGCGTCATCACACCAATTAGCTACGCAGATTATGCAGCACCAATCGTGGTCGTAAAGAAGAAGAATGGCCGTATACGTATCACCGTTGATTACTCCACAGGCCTCAATAACGCACTCGAGCCAAACAAGTACCCACTGCCAACGCAAGAGGGAATTCTGGCTAAACTCGCTGGCAATACAGTTGTCACCGTCATGGACATGTCGGATGCTTTCTTACAAGTGGAACTGGATGacgtttccaaaaaattgatgcCGATCAATACACACTGCGGCCTGTTTCAAGTGAACCGGTTGCAACCGGGGGTTAAAATTGCTTCTGGTATTTTCCAACAGTTGATGTACACAATGACAGGCGGTCTAGAGGGCGCACTACATTGGATCGACGATATTATCATTGGAGACAAAGACGACAAACAACACCGTGAGCGCCTCTTCAGCGTGATGAGCCGCATGCAAGAATACGGTTTCATTCTCAAGCGATCTAAGTGCTCGTTCGGTCAGAAATCCGTCGAGTTTCTGAGTCACATTATCGATGAAACCGGTATCCGACCAAATCCAGCGAAGCTGGAAGTCATTCAGCAGCTGCCAGCGCCATCCGACATTAATCAACTTCGCGCTATCTTGGGCGCCGTGAACTGGTATGGAAAGTTTATACCAAAGCTCAAGGATATGCGTGGCCCACTCGATGAACTGCTACAAGAAAGCGTCGAATATAAGTGGACTGAAGCTCGAGCCAATGCATTCTTCCGGCTGAAGCAAGTGCTCGCATCTGACCTGGCCCTCACACACTATGATCCAGCCAAGAAAATCATCGTCGCAGCTGATGCGTCCAGCTATGGTTGGGGAGGGGTACTCATGCACCAGGTCGAGGACGGCACCAGTAAGCCCGTCCAACGAGAAGCCTTAGCTCTAGTGCGGACGCTAAAGAAATTCCATCGCTTTGTCTACGGTCGCAAGTTTGAGCTCCAGACGGACCATCAGCCGCTGCTTTCGATCTTCGGAGCGAAAAGTGGTATTCCAATCTACACAGCAAATCGCCTGCAGCGATACGCAGAGAACCTTCTCGCCTACGACTTCCAAATTAAGTATGTGGGCACTAAAGGATTCGCCTATGCCGATTTTATATCCAGACTAATCGCCGCACAACTTCCTCTTGAATCTGAAGACACGGTCATTGCAACGGTCCGTCCGCCAAATCGTTGCCAGTCAACTTTAGTGACATTCAAAAGGCAACCACGGAAAGTGACGTACTTCAGAAGGTCGCTGATTACATCATTGATGGCTGGCCACGTCAGCGAAAACAAATTTCCGACCCAGCAGTAG
- Protein Sequence
- MCLAAKEFGNMVLNDPTRDWPCIKCMEDIKIAFKSKEDNITSDDTITLEINNTVEDSISNLASGDERNSDREQANLIADKFEKSSVDLDSGAKKSENRGEGQVSIEQSIATPALYECEKCNMKFITYKGLINHMRFHPDINLFECERCGKEFHTVSRYHRHCYSHATDTPFICQICNKGFKSPILLKQHELIHQKVKILPCPHCDKWFCHDKALKQHLSFIKEKKIACTMCDKKFRYNSLLKVHMDIAHELGVNQGSETIGHIRTVKKTLQKQFACEKCGKLLATEFGLRAHISRKHNMERPFQCSYCSKSFSTATSLQCHIQHHINSKNPKMDPKTIESYLKYKCDECDRAFTNSVFLKNHKIIHSGSKDHVCTQCGKGFAFKWYLVRHVRLVHDTTYPTNIICSICRKVSSSTHALESHMLSHTGETPFHCTFCDSKFRYKKSLRIHAGFCSSSRIWRQLQQKRRNDPGRRSNAISTTHPNSTIKFVTATVDGTKVKLQHDSGSDLTIISQANWMKLGERNLRRHKGTAVNASGKPISILGCFDATLKIGNHEATGIIYVSPSMLNLFANEWMTKLKLWDVPPSAYCHNVNAVHSGPHPLENEIEAKFPMLFSETLGRCNKIKASLTLKPGANPIFRRARPVPHAAAKPIEDELIRLQCQCVITPISYADYAAPIVVVKKKNGRIRITVDYSTGLNNALEPNKYPLPTQEGILAKLAGNTVVTVMDMSDAFLQVELDDVSKKLMPINTHCGLFQVNRLQPGVKIASGIFQQLMYTMTGGLEGALHWIDDIIIGDKDDKQHRERLFSVMSRMQEYGFILKRSKCSFGQKSVEFLSHIIDETGIRPNPAKLEVIQQLPAPSDINQLRAILGAVNWYGKFIPKLKDMRGPLDELLQESVEYKWTEARANAFFRLKQVLASDLALTHYDPAKKIIVAADASSYGWGGVLMHQVEDGTSKPVQREALALVRTLKKFHRFVYGRKFELQTDHQPLLSIFGAKSGIPIYTANRLQRYAENLLAYDFQIKYVGTKGFAYADFISRLIAAQLPLESEDTVIATVRPPNRCQSTLVTFKRQPRKVTYFRRSLITSLMAGHVSENKFPTQQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -