Thel092030.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tipula helvola
Gene Symbol
zfh1
Assembly
GCA_963556165.1
Location
OY744483.1:50928436-50929934[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 1.5 5.8e+02 4.1 0.9 2 23 178 202 177 202 0.85
2 10 3 1.1e+03 3.2 0.4 6 23 211 228 210 228 0.97
3 10 3.5e-07 0.00013 25.0 0.4 1 23 234 256 234 256 0.99
4 10 0.00014 0.05 16.9 4.0 1 23 264 286 264 286 0.97
5 10 1.6e-05 0.0059 19.8 0.2 1 23 294 316 294 316 0.97
6 10 1.1e-06 0.00043 23.4 0.1 1 23 322 345 322 345 0.96
7 10 0.00068 0.25 14.6 2.4 2 23 354 375 353 375 0.97
8 10 0.085 32 8.0 5.6 1 23 381 404 381 404 0.87
9 10 3.4e-06 0.0013 21.9 2.7 1 23 410 432 410 432 0.97
10 10 0.026 9.8 9.7 3.8 1 21 438 458 438 459 0.95

Sequence Information

Coding Sequence
atgaACATTGACGACATTCAGTATATATGCCGTTTGTGCTTAATAAAACCAGAGGATTACGAGGACGCTCTATTCGATGACCGACTCAAGGAATACCTGAAGTTATTCTTCAAAATTgatATTGAATACGACCAGAAATATTCTAGCTTAATATGCAAGTGTTGCTTGCAAACGTTGAAAGCTGTTTGTGAATTTTATGATAAAGTACTGGCGAATCAGAAATTGCTGAGTGAACGCCATACAAAATTGctcgaaataaaaaatgaagttctTAACGCGGAGATGAGCTTAGGTGAAGTATTGAATGATGATTTTGGTTCGTCTCCAAATAGTTTCCACAGTGACAATGACGAGATAAATAGTGAGGACGTAGAAATGGAATCTACCCAAGAATCCAATATAAAAGAAGAACATAGTGAAGAAAGTTCTGATTCCGATGACGAAacggaaaagaaattaaatgataaatcgaaaaaaaaccGCCAAACCAAGACGAACTACGACGAACAAATTCGAGAATTTATGCCACTTGTCTGCGACCAGTGCAACAAATCAGAAATCTTCGATACATTTAAAGAACTGACGGAACATTTTGAAACGGTACATAAATGTCGCGGTTATACAACATGTTGTGATAAAAGGATTTACCGTAAAGACGTTCTCGTCAGTCATATCACGAATCATATTGATCCGGAGGCGTACAAATGCCCAGAATGTGGTAAAATCAGTAAAAGTAAAACCCTCCTTCAAATCCACATGAAAATTCATTTGCCTGTCGAGGAACGGGAGTTCCAGTGTTGCATTTGTACCCAACGTTTCGCCACCAAATCGCATCTCGCCAACCATGAAATATCGCACCTTCCAGattccgaaaaaaaattctcgtgTGACGAATGTGGCAAAGCATTCGGTGTTAAAAATGCCCTCACTAAACACAAACTTATTCACTCGTCCGAACGAAATTTCGTGTGCGAAGACTGTGGCCGATCATTTGCAATGAAAGCCAACCTACAGTATCACATCAACAATATCCATAGTAATGAACCAAAACCGAAACTACAGTGCCATTTATGTCAAGCttggtttaaaaataatgaCACACTCCGCAAACATATTCGCCAGCACAATGACCAAACGGAATATAAATGTGAACACTGCGATAAAGTGTGCTCGTCGCGTAACGTTCTTTGGTGTCATGTCCggtttgtacataaaaaaattcgtaaacATGAGTGTAATGTATGTGAACGTAAATTTCGGCGCAAATACGAACTAACCGATCACATGGCGAAGCATACGGGTCAACCGTTATATAAATGCCAAAATTGTTTGCGGCCTTTTATGTATAGTTCGCATTTCTCTCAGCACCGTAAAAAATGTCAGAATATGACAACGGCCACGGATAATGTGCCGATCCAGATATTTGGCGAATTTTAA
Protein Sequence
MNIDDIQYICRLCLIKPEDYEDALFDDRLKEYLKLFFKIDIEYDQKYSSLICKCCLQTLKAVCEFYDKVLANQKLLSERHTKLLEIKNEVLNAEMSLGEVLNDDFGSSPNSFHSDNDEINSEDVEMESTQESNIKEEHSEESSDSDDETEKKLNDKSKKNRQTKTNYDEQIREFMPLVCDQCNKSEIFDTFKELTEHFETVHKCRGYTTCCDKRIYRKDVLVSHITNHIDPEAYKCPECGKISKSKTLLQIHMKIHLPVEEREFQCCICTQRFATKSHLANHEISHLPDSEKKFSCDECGKAFGVKNALTKHKLIHSSERNFVCEDCGRSFAMKANLQYHINNIHSNEPKPKLQCHLCQAWFKNNDTLRKHIRQHNDQTEYKCEHCDKVCSSRNVLWCHVRFVHKKIRKHECNVCERKFRRKYELTDHMAKHTGQPLYKCQNCLRPFMYSSHFSQHRKKCQNMTTATDNVPIQIFGEF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01455160;
90% Identity
iTF_01460572;
80% Identity
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