Thel110431.1
Basic Information
- Insect
- Tipula helvola
- Gene Symbol
- -
- Assembly
- GCA_963556165.1
- Location
- OY744483.1:213913723-213914916[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.016 6.1 10.3 1.8 2 23 101 123 100 123 0.97 2 10 0.21 78 6.8 0.3 6 23 132 149 132 149 0.99 3 10 8.7e-07 0.00032 23.8 0.8 1 23 155 177 155 177 0.98 4 10 1.7e-06 0.00064 22.8 0.8 1 23 185 207 185 207 0.98 5 10 5.4e-06 0.002 21.3 0.3 1 23 213 236 213 236 0.96 6 10 0.013 4.7 10.7 1.1 1 23 242 265 242 265 0.96 7 10 0.0081 3 11.3 0.4 2 23 274 295 273 295 0.97 8 10 1.4e-06 0.00051 23.1 0.5 1 23 302 325 302 325 0.97 9 10 5.6e-07 0.00021 24.4 0.5 1 23 330 352 330 352 0.97 10 10 6.4e-06 0.0024 21.0 2.1 1 23 358 381 358 381 0.98
Sequence Information
- Coding Sequence
- ATGCATGgtgaatttaaatcaaaacttGATGAAACAACCGAAGTAGAGAGTGCAGATCCTGAAAATAAACCTCCTATTAAATCAGAAAGGCTGAATACATACAAAGATAAAGCGACATCGCATATTATCGAGAATATATCGGAAGATGTTGCTAGCGATAATAGTTGCTCCAGTGCACCCAAGTTAAGCCCTAAAGCTAAAGTGTCAAGAAACAAATTGcggaaatctcgaaaaattgaTCCAGATGAACAAGCAAAAACTAAAGAGGAAAATAACCAAATCCATGAAAGATTTATGATGGAGTGTGAGAAGTGTAATTTCCATTTTGACACGTTTAATGATGCTCAGATTCATTATCGCACTGAACACAAAACACATGGGTATTTGCGCTGTTGTGATACAAAATTTAAGTCTCGCCCTACCGTTATGGAACACTTACAACGTCATCTTAATCCAGACGGATTTAAATGTGAACAATGCAATAAAACGTTTGTTAATAAACGTGGCCTAGCTATACATATGGAGAGGCATTTATCTTCCGAGGATAAACCATTCAAGTGTACTGAATGCCCTAAAAGTTATATTCGAAGTTTTTTATTAGAGAGGCATCTGGAATCgcataaaaatttaccaaaatatatttgtgaCGATTGTGGTAAGGAGTACAGTAACAAAATAACACTGAACATTCATAAGAGGAATGTACACGATCGTACTTTGTTCTATATTTGTGATGTGTGCGCTAGAGAATTCCGCAATAAACTTGATTTTGATCTACACCATCGAAATGTACACGATTCTGTGCCTCAACCAAAAGTCCAATGTAAAGTTTGTGGTGCATGGTTGAAAACTAAACAATCTCTACGGCAGCATATGGTTCGCCATCAAACTGTTAAACTAATGCATCCTTGTGGCGAATGTGATAAATCATTTCCGTTCCGCTGGGCTCTTCGGAACCATATTAGGACATTGCATACTAAAAAACTCTTTGACTGTAATCTGTGCGATAAACAATTTAAGAGACCCGTGAGTTTGAAGGAGCATATGGCTACGCATACCGGGGTTTCATTGTACCAGTGTCAGTACTGCCCTAAAACGTTTAACTCATCGGCTAATATGTCTTCCCATAAGAAAAAGGAACATAAAACTGAGCGAGAAGCACATCTCAAAATGAAGGCGGCCGGATTggcttaa
- Protein Sequence
- MHGEFKSKLDETTEVESADPENKPPIKSERLNTYKDKATSHIIENISEDVASDNSCSSAPKLSPKAKVSRNKLRKSRKIDPDEQAKTKEENNQIHERFMMECEKCNFHFDTFNDAQIHYRTEHKTHGYLRCCDTKFKSRPTVMEHLQRHLNPDGFKCEQCNKTFVNKRGLAIHMERHLSSEDKPFKCTECPKSYIRSFLLERHLESHKNLPKYICDDCGKEYSNKITLNIHKRNVHDRTLFYICDVCAREFRNKLDFDLHHRNVHDSVPQPKVQCKVCGAWLKTKQSLRQHMVRHQTVKLMHPCGECDKSFPFRWALRNHIRTLHTKKLFDCNLCDKQFKRPVSLKEHMATHTGVSLYQCQYCPKTFNSSANMSSHKKKEHKTEREAHLKMKAAGLA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -