Basic Information

Insect: Tipula helvola
Gene Symbol: -
Assembly: GCA_963556165.1
Location: OY744481.1:386675304-386677572[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.0057 2.1 11.8 0.1 1 23 229 251 229 251 0.97

2 15 0.0044 1.6 12.1 4.3 2 23 259 280 258 280 0.98

3 15 0.12 45 7.6 0.4 1 23 314 336 314 336 0.92

4 15 0.0056 2.1 11.8 1.3 2 23 344 365 343 365 0.97

5 15 0.015 5.7 10.4 0.6 7 23 380 397 374 397 0.85

6 15 0.00015 0.056 16.7 1.9 1 23 439 461 439 461 0.98

7 15 0.021 7.9 9.9 2.4 1 23 470 492 470 492 0.97

8 15 3.3e-05 0.012 18.8 2.1 1 23 498 520 498 520 0.98

9 15 0.00054 0.2 15.0 3.2 1 23 526 548 526 548 0.97

10 15 8.5e-05 0.032 17.5 2.7 3 23 561 581 559 581 0.97

11 15 2.7e-05 0.01 19.1 2.1 1 23 587 609 587 609 0.97

12 15 0.00032 0.12 15.7 1.3 1 23 614 636 614 636 0.98

13 15 4.5e-07 0.00017 24.7 1.7 1 23 642 664 642 664 0.96

14 15 0.032 12 9.4 5.0 1 23 670 692 670 692 0.98

15 15 7.4e-05 0.028 17.7 0.1 1 23 698 720 698 720 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.0057	2.1	11.8	0.1	1	23	229	251	229	251	0.97
2	15	0.0044	1.6	12.1	4.3	2	23	259	280	258	280	0.98
3	15	0.12	45	7.6	0.4	1	23	314	336	314	336	0.92
4	15	0.0056	2.1	11.8	1.3	2	23	344	365	343	365	0.97
5	15	0.015	5.7	10.4	0.6	7	23	380	397	374	397	0.85
6	15	0.00015	0.056	16.7	1.9	1	23	439	461	439	461	0.98
7	15	0.021	7.9	9.9	2.4	1	23	470	492	470	492	0.97
8	15	3.3e-05	0.012	18.8	2.1	1	23	498	520	498	520	0.98
9	15	0.00054	0.2	15.0	3.2	1	23	526	548	526	548	0.97
10	15	8.5e-05	0.032	17.5	2.7	3	23	561	581	559	581	0.97
11	15	2.7e-05	0.01	19.1	2.1	1	23	587	609	587	609	0.97
12	15	0.00032	0.12	15.7	1.3	1	23	614	636	614	636	0.98
13	15	4.5e-07	0.00017	24.7	1.7	1	23	642	664	642	664	0.96
14	15	0.032	12	9.4	5.0	1	23	670	692	670	692	0.98
15	15	7.4e-05	0.028	17.7	0.1	1	23	698	720	698	720	0.98

Sequence Information

Coding Sequence: ATGAGTATTAAATTAGATGAGCCAGACTTAAGCAATTGTCGAATATGTTTGAAAAGCAGCGGATTATTCCAATCGATTGTCGATGATTTAGAAGGTGGACTGAAGTTTTCTGACATTATTGCCTTGTTAGTCCCAATTGCAATTCATGAAAACGATGGCTTGCCTCAAAAAATATGCAAAAGTTGTGCAGACaacctaattttattaaaccatttacgAGATGTTTGTATTAAATCGGATACATGGTTGCGAGAgaaactcaaaaataaattcaagcaAGAAAACGAATCTCCTGCCCGTCCTTCAAACGAAGACTATCACATCATCGTAGATGACCAAGAAgaatttaaatgtgaaaaatttcaaGAGGTATTTGTCAAAGAAGACCATGTTGATGAGCAAACAAATGATCAGGCCAATGAATCTCGGATGTGTTTCGAAGAGCCCCCTCAGAATGATGATGACATCGACAGTGATAATGACATTAGCAGTGATGATGACATCGACTGTGATGATGATTCCGATAGCGATGATGATGCCGACAGCGATGATGATCCGGACTGTGATGATGATCCCGACAGTGATGATGATCCCGACAGTGATGATGATCCCGACAGTGATGATGATATCGACAATGATGGTGAACCACTGATTCAATCCAAAAATAAGAGTAAGCAGCAGTCGTATACATGCGGCGTTTGCCAAAAAGGTTTTCCTACTCGGCGTGCTGTAGCGGGGCATTCGAGAGTGCATAGCATCAAGGGTGAGCCGAATAAATGTGAGGTATGTCATGTACACTTATCGAGTCGTAGTTCACTTTACCGCCATCAGAAGATTCACTTACCAGAACCGTTTAATGATGAGCCCCATCAGAATGATAATAACATCGACAATGATGATGAGCCATTGATTCAATCCAAAAATAAGAGTAAGAAGTGGTATACATGCCGCTTTTGCAACAGGCGTTTTCCTACTATACAAGCTATAGCGGGACATTCGAGAGTGCATAGCGTAAAGGGTGAGCAGATTAAATGTGAGGTATGTAATGTACATTTAGCGAGTCGGAGATCACTTTACCGCCATCAGAAGATCCACTTAAGGTCAAACACGTTTAAACAATACGCTTGTATAAAATGTAACGGGAGAACCTTCAATAATTCTAAATCATACTCGGCACATATGAGGATACATAAAACGGACTACGAATCGGAGGTGGGATCGGCGCATAATGAACAGGACAATAATCAAAACAGTGATGAAGATATGGCAAATACGGATCCAAAATCACCCAAAAATACACAACTAAAACTTACATTTAAGTGTAAAGATTGTTTTCGGGTATTCTCAAAACGATCCTTTCTGGGGTCTCACGCTCGCATCCATCAAGAGGGTTTTACGAAGAAAGAATTTATCTGCGACATATGCAATCAACAATTTAACTGTAATATGTATCTGCAGCGGCACTTAGCACGCCATCCCGAGAAAAGAATCCACAAATGTACTTTGTgcgataaaacatttttttcaagtgGCCAACTAGCCGACCACGTGAATAGACATAACGACGTTCGGGCACATGAATGCGAAACgtgcaataaaaaattctattctATCGAAACCTTAAAAACACATCGTAACATTCATAAACCAGATTATATGTCACCGGTTAACAATTGCCTTTGTCCGCATTGTGGGAAAGTGTTTGCCAACAATTCGATTCTACGACAACATTTGACTACTCATTCGGATTCTAAATCTTTTGCATGTGAACAGTGCCCTAGCCGATTTAACTCAAGCCGATATCTCAAGAAGCACATGAAAACACACGGGACAAAACCGTTCGTCTGTAAGGAATGTGATCGcgcgtttttgaaaaaaacaacaCTAATTAAACATAAACGTATACACACAGGTGAAAAACCATTTACATGTACAATTTGTGACAAACGATTTAGAtcatcagaaaatttaaaaagacacAATCTGATTCATACCGGAGAAAAACCTTTCAAATGTAATTTATGTGATGACGACTTTAGAGAAAGATGTGAATTGAAAGTGCATATGCATAAACATTTAGGCGGCAATATATATGAATGCGAAAAATGCCCGGAAGGGTTTCGGTTGCAGAGAGAACTAAAGGAACATATACTTATACATTTTCTGGAAGAGAAGGAAAAGGAAGCTGCAGGCAAAACATGA
Protein Sequence: MSIKLDEPDLSNCRICLKSSGLFQSIVDDLEGGLKFSDIIALLVPIAIHENDGLPQKICKSCADNLILLNHLRDVCIKSDTWLREKLKNKFKQENESPARPSNEDYHIIVDDQEEFKCEKFQEVFVKEDHVDEQTNDQANESRMCFEEPPQNDDDIDSDNDISSDDDIDCDDDSDSDDDADSDDDPDCDDDPDSDDDPDSDDDPDSDDDIDNDGEPLIQSKNKSKQQSYTCGVCQKGFPTRRAVAGHSRVHSIKGEPNKCEVCHVHLSSRSSLYRHQKIHLPEPFNDEPHQNDNNIDNDDEPLIQSKNKSKKWYTCRFCNRRFPTIQAIAGHSRVHSVKGEQIKCEVCNVHLASRRSLYRHQKIHLRSNTFKQYACIKCNGRTFNNSKSYSAHMRIHKTDYESEVGSAHNEQDNNQNSDEDMANTDPKSPKNTQLKLTFKCKDCFRVFSKRSFLGSHARIHQEGFTKKEFICDICNQQFNCNMYLQRHLARHPEKRIHKCTLCDKTFFSSGQLADHVNRHNDVRAHECETCNKKFYSIETLKTHRNIHKPDYMSPVNNCLCPHCGKVFANNSILRQHLTTHSDSKSFACEQCPSRFNSSRYLKKHMKTHGTKPFVCKECDRAFLKKTTLIKHKRIHTGEKPFTCTICDKRFRSSENLKRHNLIHTGEKPFKCNLCDDDFRERCELKVHMHKHLGGNIYECEKCPEGFRLQRELKEHILIHFLEEKEKEAAGKT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -