Thel016785.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tipula helvola
Gene Symbol
-
Assembly
GCA_963556165.1
Location
OY744481.1:134523653-134526590[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 2.7e-05 0.0099 19.1 0.2 1 23 380 402 380 402 0.94
2 12 0.00098 0.37 14.1 1.7 1 23 411 433 411 433 0.98
3 12 0.00048 0.18 15.1 0.5 2 23 441 462 440 462 0.97
4 12 1.4e-06 0.00053 23.1 1.8 1 23 468 490 468 490 0.99
5 12 0.00091 0.34 14.3 1.6 1 23 497 519 497 519 0.98
6 12 1.7e-05 0.0062 19.7 1.7 1 23 525 547 525 547 0.96
7 12 6.2e-05 0.023 17.9 0.3 1 23 553 575 553 575 0.98
8 12 7.7e-06 0.0029 20.8 0.5 1 23 581 604 581 604 0.96
9 12 0.0002 0.076 16.3 2.1 1 23 610 633 610 633 0.94
10 12 0.00023 0.086 16.1 2.9 1 23 639 661 639 661 0.99
11 12 0.00014 0.054 16.8 1.5 1 23 667 689 667 689 0.97
12 12 0.00042 0.16 15.3 0.1 1 22 695 716 695 719 0.92

Sequence Information

Coding Sequence
aTGAATAGTGAAAATGGTGATGAAGCAAATGGGTACGCCAAACAACATCAACAGCAGCGGAATGTGGACGTGATGGAAATTGGGACGTGCTTCGTTTGTAACTCGGACTTTGGAAGCGATAAAAATTctgaactaaatttatttacagatCGTacaCCAATCAATGATTTATCGCCTTCATTCATTCTGTCACAAATATTGAATCGACGACTGGGAAACGATACTGTGCACTCTGATTCCCTTTGCCaacattgttttaaattgtgCCTCGAATTTGAGGAATTGGAACAACGACTAGTTGAAATACGTCTCGAATTCATTAGGAATTTTAATAATACAGCGATTACATATAATTTGGAACCAGTTGAACTGGAAGACGATGAGGTTGAAGACGATAACGTGGACGAAGATAATTTTGTAGAAGAGGATGAGGGGTGTGATGAAGAGCAAATTGTTGATGAAGGCCAGAAGCATGAAATGGCAGTGAATACAAACAGGGAAGAGGAAATCGTGGTGGAtacaatggaaaaaataccTCAGCATCATCAGGAAATATTGGAACAATATGAAATGGCCACAACTAATGAAGCTGAAAAAGGAACTAGAGTTAttcttttggaaaatttacAAGATTCAAATTCAGTGCAGAGCGGTGAAAATGGCACCACTACAACTTATTCGATGGATGCATCTCATTTTCGGGAAGAATATCTCGgcgaagaaaatcaaaatatggtTGAGGTGGTTGCTGAATCAGAAGATTATGTCGATTTAATTGTACATGAGAATCCGATAGCGATACATGATGAAAATTCTTATGAAAGCGGAATTGTTAAGGACAACTCAAAGTCATCTGATAATAGCCAGGACAGTAACCAAAATAATTTATTCGAAATAAAAGTCGAACAAAGTGATAATAGCCAAAGTGAATTCAGCATCCCTTCAAATAAATCGAAGAGTCGAAAAACTACCAAAACAGGTGTCGAAGATAAGGAGACAATTGTTCTGAGCACAAATGAAATATTCACAAGAGAAGGCGATTCCTATGTTTGTCAATTATGTACGGATAAAACTGTAATCATTTACGATGGGCGAACTATTGGGATTCATTTAAAATCGATTcatgatataaaaatttacttgtgTGACATATGCGGTCAAGATTTTCGTAAACGTAGCGAACTAACGGAGCATATGGATGAGCATGTAACGGCTACGGAAGATGGTTTTTTCACTTGTGATTTATGTAGTAGAGAATTCAACAATTTAAGATTATTCCGAATCCATAAACGAATTCATTACACAAATTCAAAGTCGTGGCCATGTACGAAATGTAACAAAAAGTATGGTTCAAAAAATCTCTTGGATGAGCATATGAATATGCATACAGGAAAACGGCCATATAAGTGTGCTCACTGCGATAAAGACTTTGCGTCTAAATATACTCTTTCGGCACACATGAAAATTCATTCAGACCGACCACGACCATTTGAATGTCGCACGTGTTCCAAGTCATTTTACAGCGGGCAAAATTTAGTACAACACGAAAAGACGCATACCGGTTTGAGGCCACATGTTTGTGAAGCATGCGATAAATCTTTTAGTACGCAACATAATTTGGAAGTACATAAAATTGTACACACCGGTTTTAAACCATTTATTTGTCGCACTTGTGGCAAAGCATTTGCACGGCGAGCGGAAATTAAGGATCATGAACGCACACATACCGGTGAAAAACCATTCAAATGTGATTTATGTCCGGCAAGTTTTGCGCAGCGATCCAATTTACAATCACATAAGAGGGCTACACATTTAGACGACAAACGGTATCAATGCGATATTTGCGATCGGCGGTTTAAAAGAAGACGTTTGTTGGACTATCATAAGAAAGCCACGCATACTGGTGAAAGGCCATTCAAATGTAGGCTTTGCTCAGCAACTTTCGTCTATCCAGAAcattataaaaaacatttacggATACACTCTGGACTTAAACCTTACTCGtgcgaaatatgtaaaaaaatgtttaatagtcgAGACAATCGGAATGCGCATCGATTTGTACATAGCGATAAGAAACCTTATGAATGTACAACATGTGGGGCCGGTTTCATGCGAAAACCATTACTTTTTGCACATATGAAACAGGCGGCTCATTTTTCCGACGCTATCATTATTAATCAACCGCGAATCCAATCGCTTACGACAGCTACAAATCCAAAAGATGGTAAAAGTgaggttttatttaaaacagaaaagGTACTTGTCGATAAAGATAATTCAAATGATGTCTTTACAGTGGAATATATTGAGGAAGCAGATGAAATGGATGACGGAGAAATAATTTGCGACGATCAACatttaatggataatgaaaTGGAATCCATACTTCCAGATGGTGATGTTGATGACGAACAAGATGAGGCAGAAGACCACGATGATGATGACAATATGTCTGAAGATCATATTATCGGTGAAGAGTTGTCGGTCGAACAAAtgttagaaaattcaaattttgcaaCTGAAACGATTGAACCAGGAACGGAAATTTTTATTACCGAAGAGGGTCAACTGTATGAAACTAGTAGCGGGACATTACATtatgtgaaaataataaataatgattcaGATACGATgaagaataacaaaaattcatcgaaaaaattagaataa
Protein Sequence
MNSENGDEANGYAKQHQQQRNVDVMEIGTCFVCNSDFGSDKNSELNLFTDRTPINDLSPSFILSQILNRRLGNDTVHSDSLCQHCFKLCLEFEELEQRLVEIRLEFIRNFNNTAITYNLEPVELEDDEVEDDNVDEDNFVEEDEGCDEEQIVDEGQKHEMAVNTNREEEIVVDTMEKIPQHHQEILEQYEMATTNEAEKGTRVILLENLQDSNSVQSGENGTTTTYSMDASHFREEYLGEENQNMVEVVAESEDYVDLIVHENPIAIHDENSYESGIVKDNSKSSDNSQDSNQNNLFEIKVEQSDNSQSEFSIPSNKSKSRKTTKTGVEDKETIVLSTNEIFTREGDSYVCQLCTDKTVIIYDGRTIGIHLKSIHDIKIYLCDICGQDFRKRSELTEHMDEHVTATEDGFFTCDLCSREFNNLRLFRIHKRIHYTNSKSWPCTKCNKKYGSKNLLDEHMNMHTGKRPYKCAHCDKDFASKYTLSAHMKIHSDRPRPFECRTCSKSFYSGQNLVQHEKTHTGLRPHVCEACDKSFSTQHNLEVHKIVHTGFKPFICRTCGKAFARRAEIKDHERTHTGEKPFKCDLCPASFAQRSNLQSHKRATHLDDKRYQCDICDRRFKRRRLLDYHKKATHTGERPFKCRLCSATFVYPEHYKKHLRIHSGLKPYSCEICKKMFNSRDNRNAHRFVHSDKKPYECTTCGAGFMRKPLLFAHMKQAAHFSDAIIINQPRIQSLTTATNPKDGKSEVLFKTEKVLVDKDNSNDVFTVEYIEEADEMDDGEIICDDQHLMDNEMESILPDGDVDDEQDEAEDHDDDDNMSEDHIIGEELSVEQMLENSNFATETIEPGTEIFITEEGQLYETSSGTLHYVKIINNDSDTMKNNKNSSKKLE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01053681;
90% Identity
iTF_01460510;
80% Identity
-