Thel010063.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tipula helvola
Gene Symbol
-
Assembly
GCA_963556165.1
Location
OY744481.1:76850912-76857440[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.00011 0.04 17.2 1.9 2 23 127 148 126 148 0.96
2 15 1.4 5.2e+02 4.2 4.6 2 23 151 169 150 169 0.89
3 15 5.7e-05 0.021 18.0 0.3 1 23 175 197 175 197 0.95
4 15 0.00073 0.27 14.5 1.7 1 20 203 222 203 225 0.91
5 15 0.0084 3.1 11.2 3.0 2 23 348 369 347 369 0.96
6 15 2.2 8.3e+02 3.6 3.7 2 23 372 390 371 390 0.87
7 15 0.0026 0.96 12.8 0.5 1 23 396 418 396 418 0.96
8 15 7.3e-05 0.027 17.7 3.3 1 23 424 446 424 446 0.99
9 15 3.5e-05 0.013 18.7 0.7 1 23 590 612 590 612 0.99
10 15 0.00034 0.13 15.6 1.3 1 23 618 640 618 640 0.98
11 15 0.00053 0.2 15.0 0.8 2 23 647 668 646 668 0.97
12 15 3.5e-06 0.0013 21.8 1.4 2 23 675 696 674 696 0.97
13 15 1.1e-07 4.3e-05 26.5 1.0 1 23 702 724 702 724 0.99
14 15 0.0042 1.6 12.2 4.4 1 23 730 752 730 752 0.99
15 15 0.00072 0.27 14.6 4.4 1 23 758 781 758 781 0.96

Sequence Information

Coding Sequence
ATGGCGATTTATTCTCTAAAACAACGGATATTTATGGTAAAACGCTACTATCAGAATGGAAATTCAACCGAAAAagttcaaaatgaatttataatcgAATATAATCAACATAATAAACCAACCGATGAGAATATTGTAGAGTTTGTTCAGCTGTTTGAGAATTGTGGCAGTGTCTTTACAAATAACAATACTAATGTTAAATTAGaggGTGATGGCGAAATATCTGCGCATCATAAACCGGAAATTATACCTCAATCAAATGATGATAAGGAAtcgttaaaattttcagaaaccgGAAGCAATACGGATGCATATTTAGACAGTGATGATAAATCAGAGACGGATGATAGTATCGAAGAAACTATTGACAATAATATGTCATGTGGGCAGTgcggtaaaaaatttaaaacgaaatggGCTTATTCGCATCATTTGAATGTACACGAAAAGGAAtgcaaaatttgtaataaaagatGTCGTAATATGATTAGACATATGACTACGCATACAGGAGAACGTTTATATGAATGCAGTGAATGTGGGTTGAAGTTCAAGAAAAGGGAACAACTGAGGGAGCATGCGGTTGTGCATTCCGATGAAAAACCGTTTAACTGTAACATTtgccaaaaatcatttaagacaACAAAACGTTTAAAGGCACACGAACCGACACATTTAACGAGTGCTGAGCGTCCCGTTAAATGTGAATATGGTAACTCAACTGAAAAagttcaaaatgaatttataatcgAATATAATCATTATAATAAACCAACCGATGAAAGTATTGTGGAACTTGTCCAACTGTTTGAGAATTTTGGTAGTGTTCTAATAAACAATGATGATCATATAAAAACAGAgGATGATGCAGAAGAATTGGCGTATAACAGTTTCGGAATCGAACCGGAAGTTAATCTATTAAATGATGAAGAAAcgttgaaattttcagaaacagAAAACGAAGTAGATTTGGATGGATATTTAGACGGTTGTGATAAATCAGAGTCGGATGATAGTGTAGGAAAAACGGCTAACGAAATTTCTTGTGCGCAATGTAGTAGAAAGTTTAAATCGAAACGGGCTTTTTCACATCATTTAAGTGTGCACGAAAAGGAATgcaaaatttgtaagaaaaaatgCCGAGATTTGGTGAAACATATGGCTATGCATACAGGAGAACGCCTTTATCAATGTAGTGAATGTGGGTCCCAGTTCAAAAGCATGGATCGGTTGAAGGAACACACGGTTGTGCATTCCGatgaaaaaccatataaatgtGATGCTtgccaaaaatcatttaaaacacGAAAACGTTTAAAGGAGCATGAACGGACCCATTTAACGAATGCTGAGCGTCCTGTTAAATGTGAAGATTCCTTTACAGTAATCGTTAAAAATCCCCTCGAAAtagatgaaaattataattgcgAGGATTCGATCAAAAAAGAAGAAGATCACTCAGATCTCGGAACCGAAGATAACGTTAATGATGACCATGATAATGATAACGATTATGAATCTGATAATAAGGATGATGTCACCGATATTATAGCAGCTAGTGTCAAATATGATGAAGACTGGGCGGATGTAAAAAATGATGATGATCAAGTTGTAAGTGATAATAAGGTAAAAGTTGAAATACCCGATTTAAGTACTACAGCAGTAAAAAGTACGGTCACAGAAGAATTGGAGCCAAGCACAGACGATTTGAAACCACCTAAAAAGAtagttaaaaaagaaaaacgtgTTTTTAATGGCGATCGAACGTATCAGTGTACAGAATGTGGAACACAATTCATAAATATGGTCcgtttaaaaaaacatatggtgaCACATTCTGATGAACGCCCATTCTCATGTGACATCTGCCAGAAACCATTTAAAACGCGGGACCGGGTGCGAGAGCACAAAAAAATCCATTTAGCCGATCGTCCtgtaaaatgtgaaatttgtggAAAAGGATTTTTACATAATGGCCGTCTCCGAAAACACATGGTTATGCACACAGGTGAAAAACCATCGGTGTGTAGTGTTTGTGGCAAATGTTTTGCATCCAATGAATCGCTAAGGGTACACAATCGAACGCATACAGGTGAAAAACCATATAAGTGTAGCTATTGTGGCAAACAATTTGTTACATCGGGTAGCTTAAAAAATCATGTGCGTATACATACGGGTGAAAAACCATACAAATGCCAGTATTGTGATAAACGATTTTATGAATCGGCTTCGTGCCGTGTCCATGAACGAACGCATACAGGTAATTATccatatatttgtaaattatgcGGAAAGGCTCATAATCATCCAAGTAATTTAAAATCTCATATGAAACATGCCCATCGTGAGGATCAAAGCTAA
Protein Sequence
MAIYSLKQRIFMVKRYYQNGNSTEKVQNEFIIEYNQHNKPTDENIVEFVQLFENCGSVFTNNNTNVKLEGDGEISAHHKPEIIPQSNDDKESLKFSETGSNTDAYLDSDDKSETDDSIEETIDNNMSCGQCGKKFKTKWAYSHHLNVHEKECKICNKRCRNMIRHMTTHTGERLYECSECGLKFKKREQLREHAVVHSDEKPFNCNICQKSFKTTKRLKAHEPTHLTSAERPVKCEYGNSTEKVQNEFIIEYNHYNKPTDESIVELVQLFENFGSVLINNDDHIKTEDDAEELAYNSFGIEPEVNLLNDEETLKFSETENEVDLDGYLDGCDKSESDDSVGKTANEISCAQCSRKFKSKRAFSHHLSVHEKECKICKKKCRDLVKHMAMHTGERLYQCSECGSQFKSMDRLKEHTVVHSDEKPYKCDACQKSFKTRKRLKEHERTHLTNAERPVKCEDSFTVIVKNPLEIDENYNCEDSIKKEEDHSDLGTEDNVNDDHDNDNDYESDNKDDVTDIIAASVKYDEDWADVKNDDDQVVSDNKVKVEIPDLSTTAVKSTVTEELEPSTDDLKPPKKIVKKEKRVFNGDRTYQCTECGTQFINMVRLKKHMVTHSDERPFSCDICQKPFKTRDRVREHKKIHLADRPVKCEICGKGFLHNGRLRKHMVMHTGEKPSVCSVCGKCFASNESLRVHNRTHTGEKPYKCSYCGKQFVTSGSLKNHVRIHTGEKPYKCQYCDKRFYESASCRVHERTHTGNYPYICKLCGKAHNHPSNLKSHMKHAHREDQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-