Basic Information

Insect: Tipula helvola
Gene Symbol: -
Assembly: GCA_963556165.1
Location: OY744481.1:386716651-386718606[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00085 0.32 14.3 2.4 1 23 253 275 253 275 0.96

2 12 0.016 6 10.3 1.1 1 23 282 304 282 304 0.92

3 12 2.5e-06 0.00095 22.3 1.7 1 23 323 345 323 345 0.99

4 12 0.0018 0.67 13.3 4.3 1 23 354 376 354 376 0.95

5 12 0.0006 0.22 14.8 0.8 1 23 382 404 382 404 0.98

6 12 6.7e-05 0.025 17.8 4.2 1 23 410 432 410 432 0.98

7 12 3.3e-07 0.00012 25.1 0.8 1 23 438 460 438 460 0.96

8 12 0.037 14 9.2 1.1 1 23 466 488 466 488 0.97

9 12 4.7e-06 0.0017 21.5 0.4 1 23 494 516 494 516 0.98

10 12 7e-05 0.026 17.8 2.4 1 23 522 544 522 544 0.98

11 12 1.4e-06 0.00053 23.1 1.3 1 23 550 572 550 572 0.99

12 12 4e-06 0.0015 21.7 0.1 1 23 578 600 578 600 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00085	0.32	14.3	2.4	1	23	253	275	253	275	0.96
2	12	0.016	6	10.3	1.1	1	23	282	304	282	304	0.92
3	12	2.5e-06	0.00095	22.3	1.7	1	23	323	345	323	345	0.99
4	12	0.0018	0.67	13.3	4.3	1	23	354	376	354	376	0.95
5	12	0.0006	0.22	14.8	0.8	1	23	382	404	382	404	0.98
6	12	6.7e-05	0.025	17.8	4.2	1	23	410	432	410	432	0.98
7	12	3.3e-07	0.00012	25.1	0.8	1	23	438	460	438	460	0.96
8	12	0.037	14	9.2	1.1	1	23	466	488	466	488	0.97
9	12	4.7e-06	0.0017	21.5	0.4	1	23	494	516	494	516	0.98
10	12	7e-05	0.026	17.8	2.4	1	23	522	544	522	544	0.98
11	12	1.4e-06	0.00053	23.1	1.3	1	23	550	572	550	572	0.99
12	12	4e-06	0.0015	21.7	0.1	1	23	578	600	578	600	0.99

Sequence Information

Coding Sequence: ATGGCTGAATTAATACCACTTCCAAGTAGGGAAAATCCGACAACAAATCTGTACATCGATTCATGTCGGATCTGCTTGGCCAAAAATACCGACCCCCAATCTTCTGTTTTTGCCGTATTAACAGCAGATATTAAGTATTGTGATTTAATAACGTTATTGGCACCGGTAACTATATATCCTAATGATGGGCtcacagaaaaattatgtaaagaATGTACCGATAATTTGATTGGAGTTTATGATTTGCGAGCACTCTGCTTGAAAACAGATCGAACGCTGCGAGCAACTGTACCCGAAGAAACAGAAACCATTGATGTTAAACCAGATATTATAGATGATAGTTGtttaatgattaaaaaagaAAGTTTGGAAGAGGGTGAATTGGAACCGGGTGAAATAAGGCATGGGATTATTCAACAGTGCTCGGAGACGGGTGATGAAATTGCGGATGAAATGAAATTGACCGATAGCTCAACAGAGAAGGAAAATGATGCGAGGCTATCACAACATATACTGGAAGATTCGATGAGTATGCACGATGATAATGAATCAATTGGTGACGATTTTTACGGAGAAGAGGACGATGACGAGTTTGACGAAGAGGACGATGATGACTATGAACCGGACAATTTGGTTAAAGACGAACCATCTGAAGTAAATGCGAAGCAAACAGATAGTACGGGGCCTGATGAAAATATTCCTGATGAACCGGACGGTTTGAATACTACAGGTGCAAAGGGTAAACGTAAAAAGCAGCACATATGCAAATTGTGTAACAAAGCATTTGACAAGGCTTACCGATTAAGACGCCACTCCAATATTCATGATTCTCGTGGCAAACAGTTTGAGTGCATCAAATGTCATATATTCTTTGCAACCGAGAGTAGCCTTATACGGCACGAGACCCTACATTCAGTAAATCTGGCAGAATCATCCACATTGCTAAATACGGACATTAAAAAGGAGTTCAAATGTATGGAGTGTGATAAAGTGTTCCAGAAACAAGAATCCCTGTCGTCTCACATGAAGACCCATAAGAACGATGTCCTAAACAAGGAATATAAATGTGAATTCTGCCCGAAAATCTTTAGCAAGCTGAACTTACTAACACGACACTGTAAATCCCACGAAGAAATGAAGGTGCATCAGTGCAATATATGTTATAAAACTTTTGCACTTGGTGGGCAGCTGTTAGACCACATTAACAAGCATCGTGGTATTAAGCCGTACGTGTGTCATGTATGCAACAAGGGATTCCAACAGTCATGCACCCTTAAGGATCATTTACGGATTCATAGTGGGGAGCAGCCATATTTATGTTCGCAGTGTGGTAAGGCATTCAATAATAGTAGTAATTTAAGGCAGCATTTAATCCGGCACACAGGTATTAAACCGTACGCTTGTAATCAATGTCCGAGTCGATTCAGTTGTCGGGCTGGGCTTAGATCACATCTTCAAATCCATACAGGTGTAAAACCATATATTTGTGACGAGTGTGGCTCTTCGTTCACAAAACCATATTCTTTGGCTAAGCATAAACGGATACATACAGGTGAAAAGCCTTATGCGTGCGATACATGTATAATGAGatttaattctTCTGACCATCTGAAACGACACATACGAACCCATACAGGAGAGAAACCCTATAAATGTAAATACTGTGAACGAGCATTTGCCCAAAGCAATGATCTGGTAAAACATACTCGATCCCATGTTGGGGATAATACCTATCAATGCAATAAATGTGACGCAGCATTTCGATTGCAAGGGGAACTTCGAGACCATATTCGGATACATTTCTTGGCGGAAAAGGAGTCTAAAATTAATCAGGGTATAATCGATGAAGAAGAGGACctgaaaataccaaaaaaaattggtaatctACAAATTTAG
Protein Sequence: MAELIPLPSRENPTTNLYIDSCRICLAKNTDPQSSVFAVLTADIKYCDLITLLAPVTIYPNDGLTEKLCKECTDNLIGVYDLRALCLKTDRTLRATVPEETETIDVKPDIIDDSCLMIKKESLEEGELEPGEIRHGIIQQCSETGDEIADEMKLTDSSTEKENDARLSQHILEDSMSMHDDNESIGDDFYGEEDDDEFDEEDDDDYEPDNLVKDEPSEVNAKQTDSTGPDENIPDEPDGLNTTGAKGKRKKQHICKLCNKAFDKAYRLRRHSNIHDSRGKQFECIKCHIFFATESSLIRHETLHSVNLAESSTLLNTDIKKEFKCMECDKVFQKQESLSSHMKTHKNDVLNKEYKCEFCPKIFSKLNLLTRHCKSHEEMKVHQCNICYKTFALGGQLLDHINKHRGIKPYVCHVCNKGFQQSCTLKDHLRIHSGEQPYLCSQCGKAFNNSSNLRQHLIRHTGIKPYACNQCPSRFSCRAGLRSHLQIHTGVKPYICDECGSSFTKPYSLAKHKRIHTGEKPYACDTCIMRFNSSDHLKRHIRTHTGEKPYKCKYCERAFAQSNDLVKHTRSHVGDNTYQCNKCDAAFRLQGELRDHIRIHFLAEKESKINQGIIDEEEDLKIPKKIGNLQI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01455074;
90% Identity: iTF_01460501;
80% Identity: -