Thel083109.1
Basic Information
- Insect
- Tipula helvola
- Gene Symbol
- su(Hw)
- Assembly
- GCA_963556165.1
- Location
- OY744482.1:356536081-356538294[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.013 5 10.6 1.4 1 19 69 87 69 90 0.93 2 13 0.043 16 9.0 0.2 2 23 127 149 126 149 0.90 3 13 0.56 2.1e+02 5.5 3.8 1 23 155 177 155 177 0.98 4 13 1.5e-05 0.0056 19.9 1.6 1 21 183 203 183 204 0.96 5 13 2.9e-06 0.0011 22.1 0.2 3 23 217 237 215 237 0.96 6 13 3.3e-05 0.012 18.8 6.5 2 23 254 275 247 275 0.97 7 13 1.5e-06 0.00055 23.0 0.5 1 23 281 303 281 303 0.98 8 13 0.00036 0.13 15.5 1.4 1 23 309 331 309 331 0.99 9 13 1.2e-06 0.00046 23.3 2.2 1 23 337 359 337 359 0.98 10 13 0.00016 0.06 16.6 1.0 1 23 365 388 365 388 0.96 11 13 0.00045 0.17 15.2 0.7 2 19 395 412 394 416 0.92 12 13 6.5e-06 0.0024 21.0 1.2 1 23 422 444 422 444 0.98 13 13 0.00046 0.17 15.2 3.1 2 23 451 473 450 473 0.94
Sequence Information
- Coding Sequence
- ATGGCAAATAAAGTGACCAAAGTGGAAATTGTTGAAAATGAGGAAATCAAATATATTATCTCGACAGTTAGTTCCTCGGACGAGGAGGAAGTAGTTGAAAAATATATGATTGATGTAGCCGCGGACGAAAAAGAGGAGCCCGAATTGATTGAGACAGCTGATGGGCGGGCCATCATCGAAATGGATCAATCAACCGTTGTGGAACATGCTTGTGGCAAGTGTGCtcaaacttttacaaattttgatAACTTTAAGAAGCATAATTCGATATGTCGACAGAGCAACCAgcccaaattttataatacttatcCGAAAAAGAAGAAACTGTTATGCTTCTGTTGTGACGAGGATAAAGTTAAAGCGCATcaAGGAAATACTCCTTGCCCGAaatgtgatttgaaatttaacacgGCATTAGGCCGTGAACGGCACATATTCTTGTTGCATGCTGACAACTCTAAATTTAAATGCAAGTCGTGCACAGCTTGCTGCCCAACCAAAGGTATACTCGATTTGCATATGCAGACTCATGCACCGTCCAAGCCATTTGAATGTGATAAATGTGGACGAGATTTTACTCGTAAACAAGGATTAACGCGGCATTTGAAGCATACCTCATGTGGGGTCAACGAGCAAGATATGTTAGCGTGTGCTGTGTGtggaaaaaaatttatacgTACGGATAATTTACGGGAGCATTTACGTGTTCATATGGGCCAAACTATCAAGAAACGAGATTTTCAGTGTTCATATTGTGAAAAGTGTTCATATTGTGAAAAATCGTTTTATACTTCTTCGCTTTTAAATATCCACATTCGTATTCATACCGGGGAGAAACCGTTCCCGTGCGACATATGCCAAAGACCATTTTCATCGACCGGGGCGCTTCGCAAACATCGTCGTACTCATACCGGTGAAAGGCcttataaatgtcaaatttgtgAATCGTCGTTCAGCGCAAAGGAGACTTTTAATCAGCATGTTAAAACCCATACAGAAGATGGGCGACATAAATGCGAAATATGTGATAAGAGTTTTATTCAGCGTATACAACTTAAAGCACATATGTTCCGCCATACAGGAGAGAATGGATTTGAGTGTCAATTATGTCGACGGGTGTTCAGTCAGAAGGCAAGATTGACTGATCATCTGAAGTACATTCATCAAGGTGAGAAACCGATTGTTTGTCTTCATTGTCCGAAAACATTTGTAAGGCAAGCTGAATATCGGCGGCACGATAAGGCGCACATGGGAATTAAAGAATTCAAGTGTGacgtttgcaaaaaaaaatttggaacaaaaaGCAAGCTGATATCCCATTTGCTTGTCCACACCAAAGAAGACCCGTGTATTTGCGAAATATGCAGCaaaaaatttattcgttttgATTGTCTGTTACGACACATCCGTGCCGTTCATCGTGAAGCGCTATTAGAAATAATCACCGAAGGAGAGCGCAAAcgtttaaaattcataaatagtACAGCAATAGCTGCGAACGTAGCGGAGGCAAATTCAACTACAAAGAAGGAAGAACACTCAAAATCGGGAGATAAAGAAATCGAGGAAAGTTGTGTTGATTGTGAGGATGATGATGTTAAAGGAGAAGAGGATGCCGATACAGTGATGTTCGAAGAAACTATTAGAAATGCGGAAGATGTAAAACCATCTATATCAAATAAACTTTCTGAACCTAATGAGATTACTTTCATGGATGATGCGaccttaaaaaaatcaattgcccaacttttaaatttactcGTTGATGAGAAAACGCTTTCTCAGTTTGGGTGGCCAGAAACTGGCGTCGACGACGTGCTCAGTTCGGTGATTAAACAGTGTGGTTATAAGCCGACGGATTATAAAGATTGTGCCGATTATACGACAAAAATGCGAGAGAATACAAAACTTTTGTTCACCGTGGTGATTGATAACGATTCGATTAAGTCGTTGCTCAATAATCATACCATTGATGATGTTATATTGCGAGTTCTTAAAATGGCACAGAATAAAAGTATGGTGGTGTGA
- Protein Sequence
- MANKVTKVEIVENEEIKYIISTVSSSDEEEVVEKYMIDVAADEKEEPELIETADGRAIIEMDQSTVVEHACGKCAQTFTNFDNFKKHNSICRQSNQPKFYNTYPKKKKLLCFCCDEDKVKAHQGNTPCPKCDLKFNTALGRERHIFLLHADNSKFKCKSCTACCPTKGILDLHMQTHAPSKPFECDKCGRDFTRKQGLTRHLKHTSCGVNEQDMLACAVCGKKFIRTDNLREHLRVHMGQTIKKRDFQCSYCEKCSYCEKSFYTSSLLNIHIRIHTGEKPFPCDICQRPFSSTGALRKHRRTHTGERPYKCQICESSFSAKETFNQHVKTHTEDGRHKCEICDKSFIQRIQLKAHMFRHTGENGFECQLCRRVFSQKARLTDHLKYIHQGEKPIVCLHCPKTFVRQAEYRRHDKAHMGIKEFKCDVCKKKFGTKSKLISHLLVHTKEDPCICEICSKKFIRFDCLLRHIRAVHREALLEIITEGERKRLKFINSTAIAANVAEANSTTKKEEHSKSGDKEIEESCVDCEDDDVKGEEDADTVMFEETIRNAEDVKPSISNKLSEPNEITFMDDATLKKSIAQLLNLLVDEKTLSQFGWPETGVDDVLSSVIKQCGYKPTDYKDCADYTTKMRENTKLLFTVVIDNDSIKSLLNNHTIDDVILRVLKMAQNKSMVV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -