Thel044796.1
Basic Information
- Insect
- Tipula helvola
- Gene Symbol
- -
- Assembly
- GCA_963556165.1
- Location
- OY744481.1:380800289-380802488[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 6.4e-05 0.024 17.9 3.6 1 23 218 240 218 240 0.97 2 15 4.2e-05 0.015 18.5 1.0 1 23 246 269 246 269 0.97 3 15 2.9e-05 0.011 19.0 1.7 1 20 275 294 275 296 0.94 4 15 1.2e-06 0.00045 23.3 1.0 3 23 308 328 307 328 0.98 5 15 0.18 66 7.0 2.5 2 23 365 386 364 386 0.94 6 15 0.58 2.2e+02 5.4 2.0 2 23 402 423 401 423 0.94 7 15 0.85 3.2e+02 4.9 3.1 2 23 439 460 438 460 0.95 8 15 0.022 8.4 9.9 0.5 1 21 466 486 466 487 0.94 9 15 0.00062 0.23 14.8 1.3 3 23 499 519 498 519 0.97 10 15 0.0041 1.5 12.2 0.3 1 23 524 546 524 546 0.97 11 15 0.00015 0.056 16.7 1.1 1 23 552 574 552 574 0.95 12 15 5.9e-07 0.00022 24.3 2.5 1 23 580 602 580 602 0.98 13 15 2.4e-07 9e-05 25.5 0.6 1 23 608 630 608 630 0.98 14 15 5.1e-08 1.9e-05 27.6 1.3 1 23 636 658 636 658 0.99 15 15 0.0033 1.2 12.5 2.7 1 23 663 686 663 686 0.96
Sequence Information
- Coding Sequence
- ATGAATCCGATCACTGTAAGGCCAAGGCTAGATTTGATGAAAATAGATTTGTTATGTCGAACGTGTTTAACTTTATCGAATAATCTAAAACCATTATTTATCGATGAGAATGATGAGGATGATTTACGTGAAATGTTGCAATCGTGTTCCGGactaaatATTTATGCACGGGACGGTATGCCGGCCAGTATTTGCTCGGACTGTCTAAATAAACTACGTATTGCTTATGATTTTCGGCGACAGTGTAATACTTCGCATAATACGTTGGTAGATTTTATGAAGACAAAAACAGCCTGTAGGTCCTCTAAACATAATAAATCACCGCCGGCTCTCTTAGAGGTTCATATTAAAAGTGAGTATACAGATGATATTGGCGATCCAATAAATGAGGGAGTGCTCGAAAAGGAAAACTTGGATGGGGATAATATTAAAACCGAGCGTGATGAAGTAGACTATTTGATTTCCACCGCGCCTAGTGTCCCCatcataaatttcaaagtagACTATGAAAGTAAAATGGAAGAGTCCAGTAATGTAAGCAATGCTGGAGATGAAAGAGAGATAATTGGCGAGGTTGCAGATCCATTAAGCGACAGTAAAATTGATCAAGATGGCCCCCTTATAGAATCACAACCTAAAGCTGTTCAGCTTCATTATTGTGATCAGTGTGATAAAAAATACTCCGTGCTGAAAAACCTACGGCGCCATCAATTGTCGCATTTGGAAATAAAGCCTTACTCATGTGATCAGTGCGATAAGACGTTCTCTAGCCTAGACgacaaaaatattcatattcAGCGGAAGCATTCGAAAATTAAACTTCATAAGTGTGACAAATGCGAAAAATCTTTCGCAAAACCGTATAATTTTCGGAGGCATCGAGAGATCTGCGGGCGGAAATTGAAGCCCTGGCTAGAAATCTGTGAAATTTGTCAGAAGACGTTTACTTCATTAAAAAGTCTTAATATTCATATGAAAACCCATGAAACCGCTGAGGTTCAAGACTTCACCTCAAACCAAGAAAACAGTGATCATCTAGAGACGCATTCGAAAAACATACCAAAGCAAGAGACGGCTGAGGCTGAAGAATGGACATGTACTTTCTGTCCACAGAAGTTCACCTCAAAGCAAGAACATAGTGATCATTTAGAGACGCATTCGAAAAACATACCAAAGCAAGAGACGGCTGAGGCTGAAGAATGGACATGTACTTTCTGTCCACTGAAGTTCAACTCAAAGCAAGAACACAGTGATCATCTAGAGACGCATTCGAAAAACATACCAAACCAAGAGACAGCTGAGGTTGAAGAATGGACGTGCACTGCCTGTTCAAAGAAGTTCAACTCAAAACAAGAGCACAGTGACCATTTGAAGATGCATTCGGAAGAAAAACCATACAAATGTGACGACTGCGATTCGACTTTTAATTGGCTGAGTAGTTGGAAAAGGCATCGCCAAAACTGCTGGCGGATTGTAAGGTTTGGTGCTAAAATCTGTGACGTTTGTCAACAGTCATTTACTTCAATAAAAAAGCTAAAGTCTCATAGGAAAATACATCGCACTAGAGGATATGAGTGCTATTTCTGTCCAAAGGGGTTCAAGTCAATGGAGGAACGGGCTGATCATATGAAGGCTCATGAAAAGGAACTATTGTTCTTGTGTTGCGAGTGTGGTTTGCGATTTGGTCGTAAAGGTGATCTAGTTAGCCATATGCTGCGGCACAGTGGCGAGAAAAATCATCAATGTAAATACTGTGGCAAAAAGTTTCCACGACCCTCTGAATTAACCATGCACGAACGTTATCACACGGGAGAGAAAAAATATCAGTGCACGATTTGTGGTAAAAGTTTTCCACGTTCATATTCTCTATCGATTCATAATCGAGTGCATACCGGGGAACGGCCTTTCAAATGTTCGCAATGTGATAAGAGTTTTGCCCAGAAGAATGATCTAACGGCACATATTCGGCGACACACCGGCGAACGATTCAAGTGTGACTTATGCGACAATGGTTTCATTCATAGTTCCCTTCTATCGCAACATAAAAGCAAGAAGCacggaattaattttaaatcgcaGCGGCTCGAAAAGTTTTTTCCAAAGTCAACTAAAGATTTAAATTCTGAATAA
- Protein Sequence
- MNPITVRPRLDLMKIDLLCRTCLTLSNNLKPLFIDENDEDDLREMLQSCSGLNIYARDGMPASICSDCLNKLRIAYDFRRQCNTSHNTLVDFMKTKTACRSSKHNKSPPALLEVHIKSEYTDDIGDPINEGVLEKENLDGDNIKTERDEVDYLISTAPSVPIINFKVDYESKMEESSNVSNAGDEREIIGEVADPLSDSKIDQDGPLIESQPKAVQLHYCDQCDKKYSVLKNLRRHQLSHLEIKPYSCDQCDKTFSSLDDKNIHIQRKHSKIKLHKCDKCEKSFAKPYNFRRHREICGRKLKPWLEICEICQKTFTSLKSLNIHMKTHETAEVQDFTSNQENSDHLETHSKNIPKQETAEAEEWTCTFCPQKFTSKQEHSDHLETHSKNIPKQETAEAEEWTCTFCPLKFNSKQEHSDHLETHSKNIPNQETAEVEEWTCTACSKKFNSKQEHSDHLKMHSEEKPYKCDDCDSTFNWLSSWKRHRQNCWRIVRFGAKICDVCQQSFTSIKKLKSHRKIHRTRGYECYFCPKGFKSMEERADHMKAHEKELLFLCCECGLRFGRKGDLVSHMLRHSGEKNHQCKYCGKKFPRPSELTMHERYHTGEKKYQCTICGKSFPRSYSLSIHNRVHTGERPFKCSQCDKSFAQKNDLTAHIRRHTGERFKCDLCDNGFIHSSLLSQHKSKKHGINFKSQRLEKFFPKSTKDLNSE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01460495; iTF_01460479;
- 90% Identity
- -
- 80% Identity
- -