Basic Information

Insect: Tipula helvola
Gene Symbol: -
Assembly: GCA_963556165.1
Location: OY744481.1:393283435-393285296[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00057 0.21 14.9 2.3 1 23 138 160 138 160 0.97

2 14 0.0013 0.49 13.7 1.4 1 23 167 189 167 189 0.98

3 14 2.7e-05 0.01 19.1 1.1 1 23 237 259 237 259 0.97

4 14 0.00046 0.17 15.2 1.2 1 23 266 288 266 288 0.98

5 14 1.8e-05 0.0069 19.6 0.7 1 23 305 327 305 327 0.99

6 14 1.7e-05 0.0062 19.7 1.0 1 23 336 358 336 358 0.98

7 14 3.1e-05 0.012 18.9 0.2 1 23 364 386 364 386 0.98

8 14 7.5e-05 0.028 17.7 2.0 1 23 392 414 392 414 0.98

9 14 1.1e-06 0.00041 23.4 1.2 3 23 422 442 420 442 0.95

10 14 0.00062 0.23 14.8 2.4 1 23 448 470 448 470 0.97

11 14 0.0001 0.038 17.2 2.3 1 23 476 498 476 498 0.98

12 14 0.00011 0.041 17.1 2.3 3 23 506 526 504 526 0.98

13 14 6.9e-07 0.00026 24.1 0.6 1 23 532 554 532 554 0.99

14 14 4.2e-05 0.016 18.5 2.0 1 23 560 582 560 582 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00057	0.21	14.9	2.3	1	23	138	160	138	160	0.97
2	14	0.0013	0.49	13.7	1.4	1	23	167	189	167	189	0.98
3	14	2.7e-05	0.01	19.1	1.1	1	23	237	259	237	259	0.97
4	14	0.00046	0.17	15.2	1.2	1	23	266	288	266	288	0.98
5	14	1.8e-05	0.0069	19.6	0.7	1	23	305	327	305	327	0.99
6	14	1.7e-05	0.0062	19.7	1.0	1	23	336	358	336	358	0.98
7	14	3.1e-05	0.012	18.9	0.2	1	23	364	386	364	386	0.98
8	14	7.5e-05	0.028	17.7	2.0	1	23	392	414	392	414	0.98
9	14	1.1e-06	0.00041	23.4	1.2	3	23	422	442	420	442	0.95
10	14	0.00062	0.23	14.8	2.4	1	23	448	470	448	470	0.97
11	14	0.0001	0.038	17.2	2.3	1	23	476	498	476	498	0.98
12	14	0.00011	0.041	17.1	2.3	3	23	506	526	504	526	0.98
13	14	6.9e-07	0.00026	24.1	0.6	1	23	532	554	532	554	0.99
14	14	4.2e-05	0.016	18.5	2.0	1	23	560	582	560	582	0.99

Sequence Information

Coding Sequence: atgGAAAATATAGATGAGAATGTGTGCCGAATATGTTTGGTGGCTACCAACGTAGACGAAAGCCAAGGGATATTTGATGTATTCTCCAATGAGTTAACATATTCTGATGTTGTTATATTAATTGCTTCTATAGAATTAAAGCCAAACGATGGCCTGCcgaataaattatgtaaaaaatgttCGGACCGTGCCAATGATGCTTATGACTTTCGTAAACTGTGTATAAGCTCAGATAAgcttctaaaaacaaaaacagaggCTCCGAACATTGTAAAAGTGGAAGTGCCGGAAGGTGATGTGAAAATTGAAGATTCCGACGATGATAATCTTGATGATGCGTGGATTTGTAATCCACTCGATGAAATAGAGgaagaaattgaaatgtcaCCACCACGCAAAGagaaaaagcaacataaatgtgaaatttgcttcaaaatatttgataaaccaTTTCGCCTACAACGGCATTTGAGTGTTCATACGGCTAATGGGAAAGAGTTTGAATGCGATGTATGCCATAGATATTTTGCTTTAAGAGGGACTCTCTTGAAACACAAAATGGTACATGATGGTGAAACTTCGGAGCAACCCATTGATGACCAGCCGCCAATTGATGATAGCCAGGATGATGATTTAAATGATGTAGATTACGTACCGCTTGTAAAAGTGGAACAAATACCGGAAAAACCGCGTAAAGTTCGAAAAACGCATAAATGTGAAATTTGCTCTAAAGTATTTGATAAACCGTCCCGGCTACAGCGACATGCATCTGTACATGCTGCTAATGGAAAAGAATTTGAGTGTAACATATGTCATCGTTTTTTTGCAGCTGGAAGTACTCTAATTCGTCACAAAATCACTCATGCTGTTCAAGCTCAGGAAATCAATGATGGCTCGAATCCGAAAAAACCATTCAAATGTTTTGAATGTGACCGAATATTTGAGAAACAGGAGTCCATGGCATCCCATATGAGGATACACAAAACCGATTCAACAGTTAAAGAGTATAAATGCGATTACTGTCCAAAAGTATTCACTGAAGTTAATTTACTGACGAGGCATTCCAAATCACATGTAgaaatgaaagtttttaaatgcGAAATATGCCCAGAGAGTTTTGGCTCTAGACCGCAATTGATTGATCATACCAATAAGCATAAAGGTTTAAAGCCATACGAATGTACCatatgtgaaaaaaaatttcattcttcAACCGTGCTAAACCAGCATATAAAGATTCACACGGATGATAAATCTCATTTGTGTCCACAGTGTGGTAAAGGATTTAAAAATAACGGATATTTAAAGCAACACATGATTTCACATTTGGgcgaaaaaatatttgcttgtCCGCAATGTCCAAATAAATACTGTACAAaaggaAAGTTGAAATCTCATCTTCAAAGCCATTCCGGATTAAAACCATTTGTCTGTGAATTATGTGGCTCTAGTTTTACTAAGCATTATACTTTGACGGTACATAAAAGAATTCACTCAGGCGAAAAACCATTCGGATGTGATACTTGTCCAAAACGATTCATTTCATTAAATCATTTGAAACGACATTCTCGTGTCCACACAGGCGAGAAGCCTTACAAATGTCAATACTGCGAACGTGCATTTGCTCAAAGTGGCGATCTGATTAAACACACCCGATCTCATATTGGTACAAATACGtataaatgtgataaatgtGAAGCAACATTTCGATTACATGGCgaacttaaaaaacatattcaAATGCACTTTTTGGCCGAAAAAGAAATGATGGTAGaaacaaaaagtgaaaattaa
Protein Sequence: MENIDENVCRICLVATNVDESQGIFDVFSNELTYSDVVILIASIELKPNDGLPNKLCKKCSDRANDAYDFRKLCISSDKLLKTKTEAPNIVKVEVPEGDVKIEDSDDDNLDDAWICNPLDEIEEEIEMSPPRKEKKQHKCEICFKIFDKPFRLQRHLSVHTANGKEFECDVCHRYFALRGTLLKHKMVHDGETSEQPIDDQPPIDDSQDDDLNDVDYVPLVKVEQIPEKPRKVRKTHKCEICSKVFDKPSRLQRHASVHAANGKEFECNICHRFFAAGSTLIRHKITHAVQAQEINDGSNPKKPFKCFECDRIFEKQESMASHMRIHKTDSTVKEYKCDYCPKVFTEVNLLTRHSKSHVEMKVFKCEICPESFGSRPQLIDHTNKHKGLKPYECTICEKKFHSSTVLNQHIKIHTDDKSHLCPQCGKGFKNNGYLKQHMISHLGEKIFACPQCPNKYCTKGKLKSHLQSHSGLKPFVCELCGSSFTKHYTLTVHKRIHSGEKPFGCDTCPKRFISLNHLKRHSRVHTGEKPYKCQYCERAFAQSGDLIKHTRSHIGTNTYKCDKCEATFRLHGELKKHIQMHFLAEKEMMVETKSEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01052488;
90% Identity: iTF_01458840; iTF_01460477;
80% Identity: -