Thel046879.1
Basic Information
- Insect
- Tipula helvola
- Gene Symbol
- ZFY
- Assembly
- GCA_963556165.1
- Location
- OY744482.1:9685447-9688101[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 20 0.00034 0.13 15.6 3.4 1 23 116 138 116 138 0.98 2 20 0.00018 0.068 16.5 2.4 1 23 144 166 144 166 0.96 3 20 0.0008 0.3 14.4 2.8 2 23 173 194 173 194 0.97 4 20 6.6 2.5e+03 2.1 0.8 1 10 200 209 200 209 0.91 5 20 9.6e-07 0.00036 23.6 0.5 3 23 248 268 247 268 0.98 6 20 6.5e-06 0.0024 21.0 2.0 1 23 274 296 274 296 0.97 7 20 0.24 90 6.6 6.7 1 23 302 325 302 325 0.95 8 20 0.0014 0.51 13.7 2.7 1 23 337 360 337 360 0.94 9 20 3.1e-07 0.00011 25.2 0.3 2 23 439 460 438 460 0.96 10 20 0.00062 0.23 14.8 3.7 1 23 466 488 466 488 0.98 11 20 0.051 19 8.8 1.6 1 21 495 515 495 518 0.90 12 20 0.0093 3.5 11.1 0.3 2 23 526 547 525 547 0.92 13 20 0.0018 0.69 13.3 7.2 1 23 585 607 585 607 0.98 14 20 0.012 4.4 10.7 1.0 1 19 613 631 613 635 0.90 15 20 0.00063 0.23 14.8 1.0 1 23 641 663 641 663 0.98 16 20 2.8e-05 0.01 19.0 5.7 1 23 669 691 669 691 0.99 17 20 2e-05 0.0076 19.4 1.1 2 23 720 741 719 741 0.97 18 20 0.00013 0.05 16.9 2.1 1 23 747 769 747 769 0.98 19 20 0.0024 0.91 12.9 2.6 1 23 778 800 778 800 0.98 20 20 0.0031 1.2 12.6 3.6 1 23 806 828 806 828 0.95
Sequence Information
- Coding Sequence
- ATGGATTCgcaaacatttttcatattGGAGAATAATGTGCTAATGCCAATTGACCAAGCTGATATCTGTTACATAATTACTTCCGAATCGCTATTGCCACTTTCAAATGACAATATTACTCTAAATCTGGCTGAAGAATCTTTCGTTGAAAACGTCGAACCTGTTTGtaattttgttgaacaattAACACCAGTTAATGAGGAGGAGCTATACACTTCCGGTTTATCATTTCCCATCGAAGAGGGAAGCAATGAAATTTTCTTGGAATATAATCAGGCTGGGTCTAAGCCTATAACCGATGAAAACACAAATCAAGATACTGAACTTATGAACATtcagaatttatacaattgtGAACACTGTGCAACGAAATTTCCGCAACTGAAACTTTTGAATCGACACAAACGCACACATGTGTATGAGAAACGATTTAAATGCGACAAATGTCACGAAACCTTTAATTTCTCGGTCAATTTAAAAGTTCACAGTATAATTCATCAAGATACATTAAAAAACGTGTGTTGTATCTGTAATAGAATATTCCGGAGATTTTCAAGTCTACGCGGTCATCTTAATTCGCATGCTGTCtcggaatattttaattgtgaacattgtgatgaaatatttttaggtaAGATATTTTATGACTGCCATTTGGAGAAGTACCACAAGAAAGAAGGTAAGGAAACTAAAATAGCCAAAGTACCTAATGGTAATAACGTTGCCAACGTAGACCGAGACTGTAAAATATGcggtaaattgtttaaaaagccCAGTATGCTGGTTCGCCACATGCGTGTGCATAATGGCGAAAAACCGTTTAAGTGTAATATTTGTGAAAGGaaattctctcaaaaaaatTCTCTCACCACACATTTACTTCTGCATACAGGGAAAAAACCGTTCCCATGTACGTTATGCTGTAGGAGATTCACACAGAAATGTAACCTAAAACTACATAAGGAAAGGGTACATAACAAGTATAGTTTGAACACGGATGCCAATAAATATCCATGCAATAAATGTTCGTGCTCGTTTCGTAAAATCGCATCGCTTAATCGACATATTACTGAATTTCACAGTGCAAATGCACGGGAATCTAAATTTGTGAATCCTGAGGTCACGTCCAAaggtgatttaaattttaatgagatTCTTTCACAAATAAATGAACTGAAACAAATTCAAGCTTCATCCACTGAGGAAGAGATgcatgaagaaaataaaattcagttagCCGATCGACTTGAAAACGGTATTTTATTACATCGTAATGTACAACAACTAAAGACTGACCGAGGTAAAAACAAGCTAAGTTGTCTTAATTGTGGAAAACAATTTACTCGGCCGTCGGATCTATTGCGACATATCCGCGTACACACAAAAGAAAAGCCGTTTGAATGTTATCTGTGTAAACGGCGATTTTCGGTCAAACGGACCCTCACACTACACTATAAAACACACGAAAGTACTTTGCGCAAATATTCGTGCAGCGTATGCTGTAAAAATTTTCGCGATATTGACACGCTAAACCGGCACGGAGCTGAATATCATGAAAATTGTAATAACTTCTTGCAGTGCTTTCCGTGCAAAGAAATTTTCTCAAATGCTGAAGAACTACAAACGCacacaaaattgcacaatcgTCGACTTTCGGTAATGAAGCGTAAAGCTTATGACCCGAGTATTCAGATGCGAGATCCGATTGTTGTTAATccagaaaagaaaaatgaagaCCCACGAAGGCGGCTATATAAATGTGATGAATGTTTCAAAAGGTTCATAAAATTATGCCATCTAAAGCAGCATCAGTTATCACATACGGATGATCGACCTTTCAGATGTGATAAATGTATAAAAACGTTTAAATCTAGAAATGCGTTAACAATCCACGATCGaggacatttaaatttaaaaccttACAAATGCGTAACGTGCggtgaaaattttgtttcaaaatctaTACTGAATCGGCACCACATAATTCATTCGGaggtaagaaattttaaatgcccATATTGTCAGAAATcgtttaaatcaaaaacagaTTGTCGCAAACATATTCGAATACATCAAGAAGAAATGTTGATATCGCCTCTTGTCGATCCCTCGGTGAGTTCAAATGACAAAACCGATAATGAACaatcaaacataaaaacatGTCAATACTGTGGTCGGTATTTCAAGAAACCGATAGATCTACGCCGACATGAACGGATTCATACTGGTGAACGACCGTTTAAATGTGATAAATGCGAAAAATCATTCTCATTGGCATCCACGCTGAAATTCCATCAACGAATCCATGATGAAACCAAGCGCAACAATATGTACACATGTCACGTGTGTTCAAATAAATATGCCTCAAAGGGCAGCCTTAACTTGCACAAACGGCTTCACACAGGTGAAAAGCCATTCAAATGCCGATATTGCGATAAAATATTCCGAACAAATGGGCACCGCAGCGTACACGAAtcgaatcatttaaaaatcgCCTATGAACGTGGTATCGATCCAaaagatgttaaaaatattcggtCGTCGAAATTCGAGAGCATCTtagaaaattttacgttcaatTAG
- Protein Sequence
- MDSQTFFILENNVLMPIDQADICYIITSESLLPLSNDNITLNLAEESFVENVEPVCNFVEQLTPVNEEELYTSGLSFPIEEGSNEIFLEYNQAGSKPITDENTNQDTELMNIQNLYNCEHCATKFPQLKLLNRHKRTHVYEKRFKCDKCHETFNFSVNLKVHSIIHQDTLKNVCCICNRIFRRFSSLRGHLNSHAVSEYFNCEHCDEIFLGKIFYDCHLEKYHKKEGKETKIAKVPNGNNVANVDRDCKICGKLFKKPSMLVRHMRVHNGEKPFKCNICERKFSQKNSLTTHLLLHTGKKPFPCTLCCRRFTQKCNLKLHKERVHNKYSLNTDANKYPCNKCSCSFRKIASLNRHITEFHSANARESKFVNPEVTSKGDLNFNEILSQINELKQIQASSTEEEMHEENKIQLADRLENGILLHRNVQQLKTDRGKNKLSCLNCGKQFTRPSDLLRHIRVHTKEKPFECYLCKRRFSVKRTLTLHYKTHESTLRKYSCSVCCKNFRDIDTLNRHGAEYHENCNNFLQCFPCKEIFSNAEELQTHTKLHNRRLSVMKRKAYDPSIQMRDPIVVNPEKKNEDPRRRLYKCDECFKRFIKLCHLKQHQLSHTDDRPFRCDKCIKTFKSRNALTIHDRGHLNLKPYKCVTCGENFVSKSILNRHHIIHSEVRNFKCPYCQKSFKSKTDCRKHIRIHQEEMLISPLVDPSVSSNDKTDNEQSNIKTCQYCGRYFKKPIDLRRHERIHTGERPFKCDKCEKSFSLASTLKFHQRIHDETKRNNMYTCHVCSNKYASKGSLNLHKRLHTGEKPFKCRYCDKIFRTNGHRSVHESNHLKIAYERGIDPKDVKNIRSSKFESILENFTFN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01460472;
- 90% Identity
- -
- 80% Identity
- -