Basic Information

Insect: Tipula helvola
Gene Symbol: -
Assembly: GCA_963556165.1
Location: OY744481.1:244332454-244333890[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 1.9 7.1e+02 3.8 0.9 1 11 2 12 2 22 0.86

2 14 0.15 55 7.3 0.0 1 23 30 52 30 52 0.97

3 14 5.7e-05 0.021 18.0 1.0 1 23 102 125 102 125 0.97

4 14 3.7e-06 0.0014 21.8 1.9 1 23 131 153 131 153 0.98

5 14 1.4e-06 0.00053 23.1 6.7 1 23 159 181 159 181 0.98

6 14 4.3e-05 0.016 18.4 0.7 2 23 187 208 186 208 0.97

7 14 0.17 65 7.1 0.7 3 23 216 237 215 237 0.97

8 14 5.3e-06 0.002 21.3 4.4 1 23 243 265 243 265 0.98

9 14 1.6e-06 0.00061 22.9 3.0 1 23 271 293 271 293 0.97

10 14 4.8e-08 1.8e-05 27.7 1.7 1 23 299 321 299 321 0.99

11 14 1.7e-07 6.5e-05 25.9 1.8 1 23 327 349 327 349 0.99

12 14 9.1e-05 0.034 17.4 2.2 1 23 355 377 355 377 0.98

13 14 3.3e-06 0.0012 21.9 2.5 1 23 383 405 383 405 0.98

14 14 1.1e-06 0.00042 23.4 1.6 1 23 411 433 411 433 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	1.9	7.1e+02	3.8	0.9	1	11	2	12	2	22	0.86
2	14	0.15	55	7.3	0.0	1	23	30	52	30	52	0.97
3	14	5.7e-05	0.021	18.0	1.0	1	23	102	125	102	125	0.97
4	14	3.7e-06	0.0014	21.8	1.9	1	23	131	153	131	153	0.98
5	14	1.4e-06	0.00053	23.1	6.7	1	23	159	181	159	181	0.98
6	14	4.3e-05	0.016	18.4	0.7	2	23	187	208	186	208	0.97
7	14	0.17	65	7.1	0.7	3	23	216	237	215	237	0.97
8	14	5.3e-06	0.002	21.3	4.4	1	23	243	265	243	265	0.98
9	14	1.6e-06	0.00061	22.9	3.0	1	23	271	293	271	293	0.97
10	14	4.8e-08	1.8e-05	27.7	1.7	1	23	299	321	299	321	0.99
11	14	1.7e-07	6.5e-05	25.9	1.8	1	23	327	349	327	349	0.99
12	14	9.1e-05	0.034	17.4	2.2	1	23	355	377	355	377	0.98
13	14	3.3e-06	0.0012	21.9	2.5	1	23	383	405	383	405	0.98
14	14	1.1e-06	0.00042	23.4	1.6	1	23	411	433	411	433	0.98

Sequence Information

Coding Sequence: ATGTTTTCATGTACATTATGTGACGCGACATTCAAATGTGAAAGTGAAAGCGTAACTCATTTAAGATGCCATTCAGATGATAGGCCATTTGAATGTCCCGATTGTGCCAATCTCTACGATGATTTAGAATTATTCGCAGAACATATGCAAGAACATGAAAGTAGCCAACAACAGGATTACGGTGAATCATTTGATCAAGCTGAGGATGATGTGATTTCGgacataattgaatttaaagagACGACGAAACAAAGAGCCCCTGTTTCGGTGGCATGGCAACTACACGACAGTAAAGTCCGTCCATTTAAATGTGATATATGTGAACGTATATTTACGCTAGCCAGCTCTTTAAAGCTGCACAAACAACGAACTCATTACGGTATTAAACCGTACGCATGTCATGAGTGTCCGCAAAAATTTGGCCAGTCAAGTGATTTGACCAAACACAAAATGACTCATTCGGACATCCGTCCACATAAGTGTGATTACTGTGATACTACATTTAGGCAGCTACATAATCTAAGAAACCACATGAAAATGCATACGAATGAACCGAGCgtttgtaaatattgtgacaaaaaatttgccCTCGCTACGAGTTTAGTACAACACCTAAAAAAGCACGAGACTGGTGACATGATACTGTGTGAATTGTGCGGTATCCCATACTCGTGTGAAAAAGAATTGAATTTGCATGTGCGTCGGAAACATACCGATGAGAAACCGCATAAATGTATGGAATGTGGTAAAGCTTTTGTACAATCTTGTGATCTGAAAAAACACGAACGAACGCATACCGGAGAACGACCGTTCAAGTGCGATGTGTGCGGAAAAACATTTTCCTTTTGGACATCTTTACGGCATCACACCACGATACACACTGGCGAAAAACCTTATCAATGTTCTTACTGTGGTCGGAGATTTACAACTTCAGGCAATTTAAAGGCACACAATCGATCACATACTGGCGAGAAGCCTTTTAAGTGTGATATAtgcaataaacaattttcacgGTCCGCTAATCTAAACGAACATAAGCGAAGCCACACTGGGCAAAAAGGTTACGTGTGTACCACTTGCAACAAGTTGTTTGCAAACTCATCCACCTACTCGCGTCATAAAAAAATACACACCGGTGAACGCCCTTATAAGTGTAAAATTTGTGACAAGGATTTTATTCAGAAAACTCATTTATTGAATCATACCCTTATTCATACCGGTGAAAAGTCTTTTTACTGTACAATTTGCAATAAAGGATACCAGCGAGCAGACACGCTGAATAAGCACATGAAAACTCATTCTAAAATAAGCTCTGATTCACGAATGATTGGAGGAAACTGCGAAACAGTCCCAATTACGGTACAGCTGCTAACTAACGATACAAATCCAAGCAGCAGCATAGTGTTTCTACTTCAACAACCAGCGAACTTTACCTAA
Protein Sequence: MFSCTLCDATFKCESESVTHLRCHSDDRPFECPDCANLYDDLELFAEHMQEHESSQQQDYGESFDQAEDDVISDIIEFKETTKQRAPVSVAWQLHDSKVRPFKCDICERIFTLASSLKLHKQRTHYGIKPYACHECPQKFGQSSDLTKHKMTHSDIRPHKCDYCDTTFRQLHNLRNHMKMHTNEPSVCKYCDKKFALATSLVQHLKKHETGDMILCELCGIPYSCEKELNLHVRRKHTDEKPHKCMECGKAFVQSCDLKKHERTHTGERPFKCDVCGKTFSFWTSLRHHTTIHTGEKPYQCSYCGRRFTTSGNLKAHNRSHTGEKPFKCDICNKQFSRSANLNEHKRSHTGQKGYVCTTCNKLFANSSTYSRHKKIHTGERPYKCKICDKDFIQKTHLLNHTLIHTGEKSFYCTICNKGYQRADTLNKHMKTHSKISSDSRMIGGNCETVPITVQLLTNDTNPSSSIVFLLQQPANFT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01460469; iTF_01458837;
90% Identity: iTF_01460469;
80% Identity: -