Tcon038413.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tipula confusa
Gene Symbol
grau
Assembly
GCA_963556175.1
Location
OY744477.1:127638599-127640200[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.0078 1.2 11.1 0.2 2 23 210 232 209 232 0.96
2 10 0.62 93 5.1 3.0 6 23 241 258 241 258 0.99
3 10 0.0016 0.24 13.2 6.4 1 23 264 286 264 286 0.95
4 10 0.00081 0.12 14.2 4.8 1 23 294 316 294 316 0.99
5 10 3.5e-06 0.00053 21.6 0.4 1 23 324 347 324 347 0.96
6 10 0.00092 0.14 14.0 4.1 1 23 353 376 353 376 0.97
7 10 0.019 2.9 9.8 2.0 2 23 385 406 384 406 0.97
8 10 0.00034 0.051 15.4 0.8 1 23 413 436 413 436 0.95
9 10 9.3e-06 0.0014 20.3 1.8 1 23 442 464 442 464 0.98
10 10 2.9e-05 0.0043 18.7 4.9 1 23 470 493 470 493 0.97

Sequence Information

Coding Sequence
atggacCAGGTGATTCCACAATATTGCCGCTTGTGCCTCATTGGACATGCAaacatgttaaatatttatgacgAAAATGAACCATCAACGTCCATCGCTATGATTTTGTCACAACATTTTTGGTTCGAGatcAAACCAGACGACCTCTATAGTAAACATATATGCATTGACTGCTGGAATCGAGTTCAAGActtccataatttttactctcaaATTTATATTGCCCATACCGAATTCTATTCAAGTTACGAAAACGTTTTGAAAATTGAATCAAATGGAAACACTTCACATGCAACAGAATTAGTTGAAGGATCGTTAGATAGAGTCCTGATCGaagaattagaaaaacaaacaaatttaattattggacACGATCCCAACCagaaaaataatcaaagtaaCGATGATTATGATATTGGGTTTcttgaaaaatgtaataatcaGCAGCTAACTGATGAAAGCGACGAAGACGATATCACTGAAAATAATTCGGAAAATGATTCAGAGTTGGCTAGTAAACCGGCAGGTAAATCgcgaaatcaaattaaaatcaaaataagagAAACTCGTGAAGAAGTGGAACGTATTGAGAAAGAGGATAAACAAATTAGCGAATATTTTAGCATGGTCTGTGAATTGTGCCCAACAAAGTTTCGTGTATATCAGGATATAAAAACACATTATCGAGTTGAACATAAAATGAAAGGATACCTGAAATGttgttctaaaaaatttgtGCAACGTTGTCATGTTCTTGATCATATTCAGCGGCATTTAAATCCTAATACCTTCAAATGTGAAATGTGCAATAAATGTTATGCGGATAAACGTGGTCTACAAAATCATAAGCATTTTCATTTGCCAAACGAGCAGAAAGCGTTTAAATGTCCGCATTGTCCGAACACATAtgctaaaaattgtttgttgcgGCAACATTTACAACGACATATTATTGATCGGGCGAAACCATTTTCCTGTGAACAATGTGGAAAATcatttgcttcaaaatatgtattgcaAGCCCATAAACGAGGGGTCCACGAGGGAGCATTTGTGCATGTTTGCGAAATTTGTGCGAAATCCTTTAAGAGTAAACTTTTTTACGAACATCATATCAAGACGATGCACAGTGAGACACCATTACCTAAACAGCAATGCCAACTATGCGGTGCATGGTTAAAGCACGAAAACAGTTTAAGAAGGCATATGAAAAGGCACGAAGATGCCGAGAGAGAACACATATGTAACTTATGTGGAAAACAATCACCAAATCGTGGTGCATTACGAAGTCATCAGAAGTATGTGCATATGGTGGAACGAGCGCACAAATGCAATGTATGTGAAAAGGCTTTTAAAAAGGCTGTAACTCTTAAAGAACACATGACAATGCATACCGGagaaattttatacaattgtcCCCACTGTCCCAAAACATTTAATTCATCAGCGAACATGCATTCACATCGCAAAAAAATGCATCCTCGTGAATTTGAGGAAACCCGTAGGCAGAGAAAATGTTACAATGAAAATCCACTACagtaa
Protein Sequence
MDQVIPQYCRLCLIGHANMLNIYDENEPSTSIAMILSQHFWFEIKPDDLYSKHICIDCWNRVQDFHNFYSQIYIAHTEFYSSYENVLKIESNGNTSHATELVEGSLDRVLIEELEKQTNLIIGHDPNQKNNQSNDDYDIGFLEKCNNQQLTDESDEDDITENNSENDSELASKPAGKSRNQIKIKIRETREEVERIEKEDKQISEYFSMVCELCPTKFRVYQDIKTHYRVEHKMKGYLKCCSKKFVQRCHVLDHIQRHLNPNTFKCEMCNKCYADKRGLQNHKHFHLPNEQKAFKCPHCPNTYAKNCLLRQHLQRHIIDRAKPFSCEQCGKSFASKYVLQAHKRGVHEGAFVHVCEICAKSFKSKLFYEHHIKTMHSETPLPKQQCQLCGAWLKHENSLRRHMKRHEDAEREHICNLCGKQSPNRGALRSHQKYVHMVERAHKCNVCEKAFKKAVTLKEHMTMHTGEILYNCPHCPKTFNSSANMHSHRKKMHPREFEETRRQRKCYNENPLQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-