Tcon038418.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tipula confusa
Gene Symbol
TY3B-I
Assembly
GCA_963556175.1
Location
OY744477.1:127662232-127673081[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 2.9 4.4e+02 3.0 0.3 2 23 879 901 878 901 0.94
2 10 0.048 7.1 8.6 0.2 6 23 910 927 910 927 0.99
3 10 1.8e-05 0.0026 19.4 2.3 1 23 933 955 933 955 0.99
4 10 5.7e-06 0.00085 20.9 2.5 1 23 963 985 963 985 0.97
5 10 6.5e-06 0.00097 20.8 0.5 1 23 992 1015 992 1015 0.95
6 10 0.038 5.7 8.9 2.2 1 23 1021 1044 1021 1044 0.96
7 10 5.7e-06 0.00085 21.0 0.3 2 23 1053 1074 1052 1074 0.98
8 10 0.044 6.5 8.7 0.7 3 23 1081 1102 1080 1102 0.97
9 10 3.2e-06 0.00048 21.7 1.1 1 23 1107 1129 1107 1129 0.99
10 10 1e-05 0.0015 20.1 2.0 1 23 1135 1157 1135 1157 0.98

Sequence Information

Coding Sequence
ATGAGTGGAGATGAAGAGCAAACACAAACCAATTCTGAGGTGTCATCCATGCATATTAAACTGCAACCGTTCTGGATGAACAACCCTCGTGATTGGTTTAACATGGCGGAGATCATTTTTGACATTCAAAAGATAAAAAGCGATAAAAAAAAGTACGTTTCAGTGTTATCAGCCTTATCACCTCAAGCAAGTCACAAAATATCGGACCTGCTTGCGGCACCTCCTAGTATAAATTGTTACGAAACAATTAAACAAGCTTTCCTCGATCGTCTGGCTCCTTCTGCTGAGCGGAAGCTCACAGAACTCTTGAGCGGACAAGATATGGGAGACATGTGCCCAACAGAAATTTTGCGACACATTCGGGTTTTGgccgaaaatcaattaaacgaTTCGGTCATAAAACAACTTTGGTTGAGGAAACTCccagaaattatcaaaattgcGATAGTAGCACAACCCGAATCAATCACATTAGAAAGGCTTGCCAAAACGGCTGATAACATGAACGAGCACATCGCATCATCGAACTCAATCGCGGCAGTTAGTGGCCAAGCAACATCATCAAGCACTCTTCTTTCGGCAGCCAACGGCTCACATATAGCCACTTTTGGTTCAAAATTGCTTCAAATCAATATTGGTCTTAAACGTCCATTCACACATGCATTCATCATTGCTGATGTGAATCGTCCAATTATTGGCGCCGATTTCATCATAAAGTTCGGACTCCTTGTCGATCTTAGGCTTAGACGGCTAGTTGATTCAACTACTCAGTTGTCAGTCAATGCCGTAACGGTTCGTACAAACACACCTACGCCTATTCATTTTACCATCGACAATGGTTACGGCACACTGCTTAAGAAATATCCATCACTTACAGCAGAACCAAATTACAATCTGCCAGTTCGACACAACGTGGTCCATCACATCGTAACTGCAGGCCATCTACCTGCATCACGACCACGTAGACTAGATCCAGTGCGACATAAAGCGGCTCTTACAGAATTCCAACACATGGTGGAATTAGGGATTTGCAGAGCATCAGCATCTCCCGTCTCTTGTCCTTTACACATGGTAAAGAAGAAAGACAACGATTGGCGACCATGTGGGGATTATCGTAGACTAAACACGATCACAACACCAGATCGCTATCCGATACCCCACATTCACAATTTCTCCATGCACTTACatggatcaaaaatattttctaaaattgatctcGTCAGAGCCTACCATCTCATTCCAGTCGCTTCCGAAGACGTTCATAAAACCGCAATAACCACACCATTTGGTCTCTTTgaatttactcgaatgccatttggtcttCGCAATGCGGCGCAAACATTTCAACGTTTTATGAACGAAGTTCTTCGTGACCTAGACTTTATCTTTGTGTACATTGACGACATTCTGGTTCCGAAAACGTGGTCGGACACACTCTCCCGACCACACGATAACGAATCAGCATCAGTCGAGACTCGCTTCGACTATAATACGATCATTCAAGCTCAAAAAtcagacttagaacttcagaatttactttctggttccagACGTCACACTAGTTCATCACAGAaactagaattttttaaactaccGGGTTTCGAAATCGTTTGCGAAACCTCTACGGGAGTAAACCGCCCGTACATTGCAGCATCACTTCGTCGAAATATCTTCGACGCACTGCACAACCTATCACATCCTGGTGTCCGTGCCACACGTAAATTGGTAACTGCTCGTTATTTTTGGCCCAGCATAAACAAGGACGTAAATCAATGGACGAAttcctgtttatcctgccaaagatCAAAAGTTCATCGCCATACCAAATCACCCCATGGGCAATTTGAAATTCCACCTGGTCGCTTTGAGCATATCCATATAGACATTGTAGGTCCACTGCCTCCATCTAATGGATATATGTATCTTCtcacctgtgtcgatcgtttcactcgTTGGCCCGAAGCTTACTGTATGTCCGACATGACTGCAGCTACCATTGCCACCACTTTTGTCAACAACTACGTATCTCGATTCGGTGTTCCACTCCACATAACCACTGATCAAGGAACGCAATTCGAGTCTAAACTTTTCACGGAGTTAACGAAGCTCCTCGGCTCACATCGAATACGCACAACGGCTTATCACCCACAAGCCAACGGAATGGTAGAACGCTTTCACAGACAACTCAAGTCTGCCCTCATGGCCCGAGGCAATACAGTCAATTGGAGCTCGGAGATCCCAATCATTTTACTTGGCATCCGAGCTACAGTGAAAGAAGATCTGAAGTGCTCACCAGCGGAAATGGTTTATGGACAAACCATTAAGCTTCCAGTTAAAGTTGAGATTGTCGATGAGAATAATCCAAATCAAAATGGATCTCCTAAATTTGAACACGTTCAGGAAGAACCAAGTCAAGATGATGATATGCACGATGACGATATTGATCTGCAATCCGAAAGTAGTAATAAAGATGAAGAAAATGATGAATtagaaataaatgttaaaaaaaaggcCAAACCCAAAACTtgtaaaaaaaccattaaaaaaactagAACTAGAAAAGTAAAACATAGTATTGAAGATCAGGATAAAGTCGAAAGTGAAGATCAACAAATtcgtgaatattttaaaatgaaatgtgAAATATGTTCGGTAGAAttggataaatttcaaaatgtccaAACACACTATCGTGACGAGCATAATCTGCGCGGCTATTTAAAatgttgcaataaaaaatatactgaGCGATCATTGTTAGTCGAGCACATCCAAAGCCATATCGATCCAAATGCTTTTAAATGCGAAACATGTAAGAAAGTTTATAACGATAAACGAGGTCTAGATAGACACATGAAGCGACATAAATCCACCGATGAGCGTCCGTTTAAATGTAATGAgtgtttaaaaacttttaagcgAAAATATTCTTTGATACGGCACACGgatattcataaaaatgaagaaaaaaaattcatttgtgaTGATTGTGGCAAACCatatcgaACCAAAGATTTACTGCAATCACATAAGAAGAATATTCACGAAGGCGCTTTTATTCATATATGTGATATATGTGCGAGAGTGTTTCGaagtaaattagtttttgaGCAACATCATCAAACGGTCCACGAGAAAAAAATCATACCAAAAGTTAAATGTCCTATTTGCGGAGTTTTCGTATCTgacaaatattatttgaaaaaacatATGAACCGACACGGCGAAAGTAAAGTGTTTTGCAATATTTGCGGAAATCAATACTTAAATAGGACGACGTTATTGAAACATATACGTTCGGTGCACACGGATAAAGTTTACGAATGTACTATGTGTGAAAAGACGTTCAAAAAATCGATTAGCCTAAAAGAGCATATGGCCACGCACACTGGAGAGATTTTGTATTCGTGTCCTTACTGtccaaaaacatttaattcatCAGGAAATATGTATTCGCACAAGAAAAAACATCCGAAAGAATATGAAGAGGCCGAAAAAATGAAAGAACAAGGAATTAAAGAATAA
Protein Sequence
MSGDEEQTQTNSEVSSMHIKLQPFWMNNPRDWFNMAEIIFDIQKIKSDKKKYVSVLSALSPQASHKISDLLAAPPSINCYETIKQAFLDRLAPSAERKLTELLSGQDMGDMCPTEILRHIRVLAENQLNDSVIKQLWLRKLPEIIKIAIVAQPESITLERLAKTADNMNEHIASSNSIAAVSGQATSSSTLLSAANGSHIATFGSKLLQINIGLKRPFTHAFIIADVNRPIIGADFIIKFGLLVDLRLRRLVDSTTQLSVNAVTVRTNTPTPIHFTIDNGYGTLLKKYPSLTAEPNYNLPVRHNVVHHIVTAGHLPASRPRRLDPVRHKAALTEFQHMVELGICRASASPVSCPLHMVKKKDNDWRPCGDYRRLNTITTPDRYPIPHIHNFSMHLHGSKIFSKIDLVRAYHLIPVASEDVHKTAITTPFGLFEFTRMPFGLRNAAQTFQRFMNEVLRDLDFIFVYIDDILVPKTWSDTLSRPHDNESASVETRFDYNTIIQAQKSDLELQNLLSGSRRHTSSSQKLEFFKLPGFEIVCETSTGVNRPYIAASLRRNIFDALHNLSHPGVRATRKLVTARYFWPSINKDVNQWTNSCLSCQRSKVHRHTKSPHGQFEIPPGRFEHIHIDIVGPLPPSNGYMYLLTCVDRFTRWPEAYCMSDMTAATIATTFVNNYVSRFGVPLHITTDQGTQFESKLFTELTKLLGSHRIRTTAYHPQANGMVERFHRQLKSALMARGNTVNWSSEIPIILLGIRATVKEDLKCSPAEMVYGQTIKLPVKVEIVDENNPNQNGSPKFEHVQEEPSQDDDMHDDDIDLQSESSNKDEENDELEINVKKKAKPKTCKKTIKKTRTRKVKHSIEDQDKVESEDQQIREYFKMKCEICSVELDKFQNVQTHYRDEHNLRGYLKCCNKKYTERSLLVEHIQSHIDPNAFKCETCKKVYNDKRGLDRHMKRHKSTDERPFKCNECLKTFKRKYSLIRHTDIHKNEEKKFICDDCGKPYRTKDLLQSHKKNIHEGAFIHICDICARVFRSKLVFEQHHQTVHEKKIIPKVKCPICGVFVSDKYYLKKHMNRHGESKVFCNICGNQYLNRTTLLKHIRSVHTDKVYECTMCEKTFKKSISLKEHMATHTGEILYSCPYCPKTFNSSGNMYSHKKKHPKEYEEAEKMKEQGIKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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