Tcon021431.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tipula confusa
Gene Symbol
-
Assembly
GCA_963556175.1
Location
OY744476.1:108572556-108575479[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 8.1e-05 0.012 17.3 0.2 1 23 378 400 378 400 0.94
2 12 0.00081 0.12 14.2 1.7 1 23 409 431 409 431 0.98
3 12 0.00011 0.016 16.9 0.6 2 23 439 460 438 460 0.96
4 12 1.2e-06 0.00018 23.1 1.8 1 23 466 488 466 488 0.99
5 12 3.9e-05 0.0058 18.3 1.1 1 23 495 517 495 517 0.98
6 12 3.5e-05 0.0052 18.5 2.0 1 23 523 545 523 545 0.94
7 12 5.1e-05 0.0076 18.0 0.3 1 23 551 573 551 573 0.98
8 12 8.5e-06 0.0013 20.4 0.9 1 23 579 602 579 602 0.96
9 12 0.00017 0.025 16.3 2.1 1 23 608 631 608 631 0.94
10 12 0.00016 0.024 16.4 2.5 1 23 637 659 637 659 0.99
11 12 0.00012 0.018 16.8 1.5 1 23 665 687 665 687 0.97
12 12 0.00051 0.077 14.8 0.2 1 22 693 714 693 717 0.92

Sequence Information

Coding Sequence
atGAATAATGAAAATGAGGCTAGTGAATATGCCAAACAACATGAACTTCAGCAGAATGtggaaatgatgaaaattgGCTCTTGCTTTGTCTGTAATTCCGGTTTTGGCAGTGATAGAATAGCAGAACTAAACTTATTTACAGATCGTACCCCAATCAATGATTTATCACCATCGTTCATTTTGTCACAAATATTGAACCGTCCACTGGCAAACAATAATGTACACTCTGATTCTCTGTGTcagaattgttttaaattgtgcCTGGAATTTGAAGAACTGGAACAGCGTTTAGTTGAAATCCGACTTGAGTTCattagaaattttaacaataCAGCTATTACATATAATTTGGAACCAGTTGAACTTGAAGACGATGAAGTCGAAGATGATAATATAGACGAAGATAATCTGGTAGAGGAAGATGATGgatgtgatgatgatgaacatgTTGTCGATGACGACCAAAAGCAGGACATGGTATTAGATGAAAACCGTGTAGAAGAAATCGAAGTAGATGAAATGGAAAAAATCCCACATCACCACCAGGAAATTTTAGAACAATATGAAATGGTTACAGCTAATGAGGCAGTCAAAGAAACTAGAGTTATTCTTCTGGAAAATTTACAAACTCCAACATTAGTGCAAGAAGTTGAACACACTGGCACAACATATTCAATAAATGCATCTCACTTTAGGGAAGAATACCTTAgcgaagaaaatcaaaatatggtCGAAGTGGTCGCAGAATCAGAAGATTATGTTGATATAATTGTCAATGAGAATCAAATGTCGATGCACGATGAAAATTCATATGAAAGCGGAATTGTTaaggataattcaaaatcatCCGACAATAGTCAGGATAGTAGCCGTAACCATATGTTCGAAATTAAAGTCGAACAAAGTGACAATAGCCAAAGTGGATTTAGCAttccatcaaataaattaaaaggacgtaaatcaaacaaaacaggGACTGGTGATAAAGAGACAATTGTTTTAAGCACTAACGAGATCTTTACACGAGAAGATGATTCATACGTCTGCCAATTGTGTACAGATAAAACTTTAATCATTTACGACGTGCGAACAATCGGAATACATTTGAAATCGATacatgatattaaaatttatttgtgtgaCATATGTGGCCAAGATTTTCGTAAACGCAGCGAGCTTACAGAACATTTGGATGAACATGTGTCGGCGACGGAAGATGGTTTCTTTACTTGTGATCTATGTAGTAGAGAATTCAATAATTTGCGACTTTTTCGAATACATAAACGAATTCATTATACCAATTCTAAATCATGGCCATgttcaaaatgtaataaaaaatttggttcaaaaaatttgttggacGAGCACATGAATATGCATACAGGAAAACGGCCATATAAATGTGCTCATTGCGATAAAGATTTTGCATCTAAATATACACTATCGGCCCACATGAAAATTCATTCCGATCGTCCACGACCATTTGAATGTCGAACATGTGGTAAATCCTTCTATAGCGGGCAGAATTTAATACAACACGAAAAGACACATACCGGTTTAAGGCCCCATGACTGTGATGCATGCgataaatcgtttagtacacaACATAACTTGGAAGTGCACAAAATCGTACACACTGGATTCAAGCCATTTATTTGTCGTACGTGTGGTAAAGCATTTGCCCGCCGAGCTGAAATCAAAGATCATGAACGTACGCATACTGGTGAAAAACCATTCAAATGTGATTTATGTACGGCAAGTTTTGCGCAACGGTCTAATTTGCAGTCGCACAGAAGGGCTACACATTTAGATGATAAACGATATCAATGCGATATTTGCGATCGACGATTTAAAAGGCGAAGGCTATTAGACTATCATAAAAAGGCAACGCATACCGGTGAACGTCCATTTCAATGTCGATTATGTTCAGCCACGTTTGTATATCCAGAACATTACAAAAAGCATTTGCGCATACATTCCGGACTTAAACCTTATTCGtgtgaaatatgtaaaaaaatgttcaatagcCGAGACAATCGAAATGCACATCGATTTGTGCATAGCGATAAGAAACCATACGAATGTACAACATGTGGAGCCGGATTCATGCGAAAACCATTACTATTTTCGCACATGAAACAAGCGGCTCACTTTTCAGATGCTATCATCATTAATCAACCGCGAATTCAATCGCTTACAACGGCAACTAATACAAAGGATGGTAAAAATGAAGTTGTTTTTAAAACAGAAAAGGTTGTTGTCGATAAAGATAATTCAACAGACGAATACATTGAGGATGGAGAACAAATGGACAGCGGAGAAATAATCGAAGATGATCAACATTTAATAGATAATGAAATAGAATCAATACTGCCCGATGATGATGACGCTGAGGAAGATGATAACGATGAAGATGACAATATTTCCGAAGATCATATAATTGGTGAAGAGTTGTCGGTTgaacaaattttagaaaattcaaattttgccaCCGAAACAATCCAACCGGGAACGGAACTTTTTATTACCGAAGAGGGACAACTTTACGAGACTAGTAACGGAACAATacattatgtgaaaattataaatgatccAAATgtgaaaaatagtaaaaaattatctataaaaatggAGTAA
Protein Sequence
MNNENEASEYAKQHELQQNVEMMKIGSCFVCNSGFGSDRIAELNLFTDRTPINDLSPSFILSQILNRPLANNNVHSDSLCQNCFKLCLEFEELEQRLVEIRLEFIRNFNNTAITYNLEPVELEDDEVEDDNIDEDNLVEEDDGCDDDEHVVDDDQKQDMVLDENRVEEIEVDEMEKIPHHHQEILEQYEMVTANEAVKETRVILLENLQTPTLVQEVEHTGTTYSINASHFREEYLSEENQNMVEVVAESEDYVDIIVNENQMSMHDENSYESGIVKDNSKSSDNSQDSSRNHMFEIKVEQSDNSQSGFSIPSNKLKGRKSNKTGTGDKETIVLSTNEIFTREDDSYVCQLCTDKTLIIYDVRTIGIHLKSIHDIKIYLCDICGQDFRKRSELTEHLDEHVSATEDGFFTCDLCSREFNNLRLFRIHKRIHYTNSKSWPCSKCNKKFGSKNLLDEHMNMHTGKRPYKCAHCDKDFASKYTLSAHMKIHSDRPRPFECRTCGKSFYSGQNLIQHEKTHTGLRPHDCDACDKSFSTQHNLEVHKIVHTGFKPFICRTCGKAFARRAEIKDHERTHTGEKPFKCDLCTASFAQRSNLQSHRRATHLDDKRYQCDICDRRFKRRRLLDYHKKATHTGERPFQCRLCSATFVYPEHYKKHLRIHSGLKPYSCEICKKMFNSRDNRNAHRFVHSDKKPYECTTCGAGFMRKPLLFSHMKQAAHFSDAIIINQPRIQSLTTATNTKDGKNEVVFKTEKVVVDKDNSTDEYIEDGEQMDSGEIIEDDQHLIDNEIESILPDDDDAEEDDNDEDDNISEDHIIGEELSVEQILENSNFATETIQPGTELFITEEGQLYETSNGTIHYVKIINDPNVKNSKKLSIKME

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01053681;
90% Identity
iTF_01458869;
80% Identity
-