Tcon038417.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tipula confusa
Gene Symbol
-
Assembly
GCA_963556175.1
Location
OY744477.1:127656937-127660615[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.021 3.2 9.7 0.4 2 23 171 193 170 193 0.96
2 18 0.033 5 9.1 0.6 6 23 202 219 202 219 0.99
3 18 8.6e-05 0.013 17.2 0.4 1 23 225 247 225 247 0.98
4 18 0.00044 0.066 15.0 2.7 1 23 255 277 255 277 0.95
5 18 3.5e-05 0.0053 18.5 0.2 1 23 284 307 284 307 0.95
6 18 0.027 4 9.4 2.1 1 23 313 336 313 336 0.95
7 18 0.013 1.9 10.4 0.2 2 23 345 366 344 366 0.97
8 18 0.058 8.6 8.3 0.5 3 23 373 394 372 394 0.97
9 18 1.9e-05 0.0028 19.3 1.9 1 23 399 421 399 421 0.99
10 18 1.5e-05 0.0022 19.7 4.0 1 23 427 449 427 450 0.96
11 18 1e-05 0.0015 20.2 0.7 1 23 702 724 702 724 0.97
12 18 1.2e-05 0.0018 19.9 0.2 1 23 732 754 732 754 0.99
13 18 3.3e-05 0.0049 18.5 0.2 1 23 760 783 760 783 0.97
14 18 0.00011 0.017 16.9 2.0 1 23 788 811 788 811 0.97
15 18 0.059 8.8 8.3 0.6 2 23 820 841 819 841 0.94
16 18 0.0027 0.4 12.5 0.2 1 23 848 871 848 871 0.94
17 18 5.7e-05 0.0085 17.8 2.8 1 23 876 898 876 898 0.96
18 18 2.9e-05 0.0043 18.7 2.7 1 23 904 927 904 927 0.97

Sequence Information

Coding Sequence
ATGGAATTTGATTCGCCAAATTGCAGATTATGTTTAACatcatttgataatttaataaacgtGTTGCAGATTGAATCAGCAAACGAAACAATCGCCTCAATTTTAACACAACACTTTTGGTTTGAGATAAAAGATAATGAAAGCAGCACAAATATTTGTTCTAGTTGTTGGACAAaagtagaaaattttcattctttttatATTCATGTTTATAATATCCACTACGAATACCTTCCGAAAGTCAAAGTCGCTGGATATCACACAAATCAATATgagtcaaataaatttaaagaaagggATGAAGACCAACTTGAGGTGCAACCTGAGGCCGCCAACAATGCTAAAAACAATGATAATGAAATTGAGATACATTTTTTGACTAAAGGCATCGTGATAagtgaaaaagaaaatacaaaaaccaacCAACGAGTTAAATTAGTTAGGCCTAGTATCGAAGATCAGGATGAGGTTGAACGAGAAAATCAGCAAATtcgagaatattttaaaatggaatgtGAAATTTGTTCGATGGAGTtcgataaatttcaaaatgtacaaattcaCTATCGTAAGGAGCATAGTCTGCGTGGCTTTTTAAGATGTTGCAATAGAAAATATACCAAGCGATCACTACTTGTTGAGCACATTCAAAGACACATCAATCCAAATGCATTTAAATGcgaattatgtaataaaatttacaatgacAAACGAGGCTTAGAAGGACACATGGAGCGACATGGCTCTGTTGATGAACGTCCATTTAAATGTAGCGATTGTCTAAAAAGTTTTacgaaaaagtttttattggtACGCCACTCGTATATTCATAAGAACGAAgagaagaaatttatttgtgttgattGTGGCAAACCatttgggACTAAAACTTTACTACAagcccataaaaaaaatattcacgaaGGTGCTAGCATTCATATATGTGATATATGTGCCAAAGTTTTTCGAAGTAAATTAGTGTTTGAACAGCATCACCAATCGgtgcacgaaaaaaaaattttacccaAAGTTCAATGCCAAGTTTGTGGTGTTTGGCTTAAAGATAAGTATTATTTGAAACAACATATGGATCGGCATGATGAAAGTaaagtattttgcaatatttgcggcaaccaatatttaaatcgaaagGCATTACGAAATCATGTACGTTCGGTGCACACAGATAAAGTTTACAAATGTAGTATGTGcgagaaaacttttaaaaaatcaattagtttAAAGGAACATACGGCCACTCACACTGGAGTCGTATTGTATACATGTCCTTACTGtccaaaaacatttaattcatCCGGCAATATGTATTCGCACAAGAAAAAACATCATCCGAAAGAATGGGAGGAGCATGAACAATTAAAGGCCACTGcatttgCAAATAACAATGGTCGCTGTAAAGGAATTCCGTTGTATTTTACAAGTCATgtaAAAAACGACGATGACTCTATTAAAGATATCTGTCACGATTGTTGGGCCAAAGTGGAagatttccatttattttatacaaaagttTATGATATTCACGCAACGTTACTTTCGAAAGTGGATATAAAAAGGGAAATAGTTGAAACGTTAAACACGAAAGAAATAGACATAAAAAACACAGAAATCAATAATACAGATTTagcaaaacaaacaaatgttGATCAACATGATGTATTACATTCTGACATGGAAGTTGAGTGGTCTGGTTCAGGTATGGCTGATGAGTGTTCAAGCGATAACTATACGGTGGCCTCAAACAGTGAcaatgacattaaaaataaaaatgatgacgAATTTACCTCATTACCTTCAGCACTGAAGCAAAATGGTAATAAACGGAAAACAAAAAGAATCCAAACTAAAAAAGAAACTGATCCGGCTAAAAAagctaaatttgaatttcaaaataaacagaTATCCGACTATTTCTCGATGGACTGTGATATGTGTCCAATGAAATTggataattttcgaattttacaaTTACACTATAGACTAGAACATAAAACTAAAGGATATGTTCGATGTTGtaataagaaatatataaaacgtGGCTTAATACTTGAACATTTGGGACGTCATTTAAATCCGGAAACATTCGATTGcgaaatatgtaataaaaaatttgtagctAAGCGAAGCTTAGAGCTCCATATGCGCAGTCACTTGCCATCAGAAGAGAGACCGTTTAAATGTCCCGAGTGTCCTAAGACATATGTTATAGCCAATCTGCTAAAACGACACCTAGAAACTCATGCAACTGAGCGAAAATTTGTGTGTGGTGAATGTGGCAAATCATTCGTGGCGGAACTTCAACTAAAATCACACCAACGAAGTATGCATGTGgccaatatttatatttgtgatgTGTGCGCAAAACCTTTTCGTAGTAAAGATACATTCAAGAAGCATCACATGTCAGTTCATGGAAAGGTTCCACTTCCGAAAGTTCAGTGTCAAATATGTAGTGCGTGGGTTAGTCATAAATATTACCTTAAAAAACATATGGCTGGTCatgctgaaaataaaacaagttttcCCTGTAATATTTGTGGTAAATCGACGCCTAATGCAGCAGCACTTCAATGTCATAATCGTGTTGTGCATACCGAAAAAGTGCATACATGTAGTTTATGtgagaaaacatttaaaagatcGATCAGCTTGAAGGAGCACATGGCATTTCATACAGGAGTTATTTTGTACAGTTGCTCTTACTGTCCAAAGACGTTTAACTCATCAGCTAACATGTATACCCATAGAAAAAAAAGTCATAAGAAAGAATGGGAAGAACATAAATTAGGGAAACACAAAGCAAATTCcgcaatataa
Protein Sequence
MEFDSPNCRLCLTSFDNLINVLQIESANETIASILTQHFWFEIKDNESSTNICSSCWTKVENFHSFYIHVYNIHYEYLPKVKVAGYHTNQYESNKFKERDEDQLEVQPEAANNAKNNDNEIEIHFLTKGIVISEKENTKTNQRVKLVRPSIEDQDEVERENQQIREYFKMECEICSMEFDKFQNVQIHYRKEHSLRGFLRCCNRKYTKRSLLVEHIQRHINPNAFKCELCNKIYNDKRGLEGHMERHGSVDERPFKCSDCLKSFTKKFLLVRHSYIHKNEEKKFICVDCGKPFGTKTLLQAHKKNIHEGASIHICDICAKVFRSKLVFEQHHQSVHEKKILPKVQCQVCGVWLKDKYYLKQHMDRHDESKVFCNICGNQYLNRKALRNHVRSVHTDKVYKCSMCEKTFKKSISLKEHTATHTGVVLYTCPYCPKTFNSSGNMYSHKKKHHPKEWEEHEQLKATAFANNNGRCKGIPLYFTSHVKNDDDSIKDICHDCWAKVEDFHLFYTKVYDIHATLLSKVDIKREIVETLNTKEIDIKNTEINNTDLAKQTNVDQHDVLHSDMEVEWSGSGMADECSSDNYTVASNSDNDIKNKNDDEFTSLPSALKQNGNKRKTKRIQTKKETDPAKKAKFEFQNKQISDYFSMDCDMCPMKLDNFRILQLHYRLEHKTKGYVRCCNKKYIKRGLILEHLGRHLNPETFDCEICNKKFVAKRSLELHMRSHLPSEERPFKCPECPKTYVIANLLKRHLETHATERKFVCGECGKSFVAELQLKSHQRSMHVANIYICDVCAKPFRSKDTFKKHHMSVHGKVPLPKVQCQICSAWVSHKYYLKKHMAGHAENKTSFPCNICGKSTPNAAALQCHNRVVHTEKVHTCSLCEKTFKRSISLKEHMAFHTGVILYSCSYCPKTFNSSANMYTHRKKSHKKEWEEHKLGKHKANSAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-