Basic Information

Gene Symbol
-
Assembly
GCA_963556175.1
Location
OY744477.1:127650203-127653564[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.031 4.7 9.2 0.5 3 23 197 218 195 218 0.97
2 18 6.9e-05 0.01 17.5 2.3 1 23 250 272 250 272 0.98
3 18 2.3e-05 0.0034 19.1 0.7 1 23 280 302 280 302 0.99
4 18 7.6e-06 0.0011 20.5 0.3 1 23 308 331 308 331 0.97
5 18 0.0039 0.58 12.0 2.5 1 23 337 360 337 360 0.96
6 18 0.027 4.1 9.4 1.4 2 23 369 390 368 390 0.97
7 18 3.9e-05 0.0059 18.3 0.0 1 23 397 420 397 420 0.97
8 18 3.9e-06 0.00058 21.5 0.6 1 23 425 447 425 447 0.97
9 18 2.7e-05 0.0041 18.8 2.8 1 23 453 476 453 476 0.97
10 18 0.031 4.7 9.2 0.5 3 23 658 679 656 679 0.97
11 18 6.9e-05 0.01 17.5 2.3 1 23 711 733 711 733 0.98
12 18 2.3e-05 0.0034 19.1 0.7 1 23 741 763 741 763 0.99
13 18 7.6e-06 0.0011 20.5 0.3 1 23 769 792 769 792 0.97
14 18 0.0039 0.58 12.0 2.5 1 23 798 821 798 821 0.96
15 18 0.027 4.1 9.4 1.4 2 23 830 851 829 851 0.97
16 18 3.9e-05 0.0059 18.3 0.0 1 23 858 881 858 881 0.97
17 18 3.9e-06 0.00058 21.5 0.6 1 23 886 908 886 908 0.97
18 18 2.7e-05 0.0041 18.8 2.8 1 23 914 937 914 937 0.97

Sequence Information

Coding Sequence
atggaTACAAATTTATCACAATGTCGCCTCTGTTTATCACAATCACCaagttttttgaatatatttactGAAACGATCGATGATAAACCAATTGCGTCCATATTAACTCAACATTTTTGGTTCGAAGTAAATGAGGATGACTCAAGTAAATATATTTGCCAAGATTGCTGGATCAAAGTGTCAGATTTTCATATAtactatttaaaagtttataatatCCACTGCGAGTTGCTTGTAAAGGTAGATCAAGGCGTTAAACTGGAGGAAATAGATGAGAAACAGAACTCGAACGAAAATGAAGTAGAATTAGTAACcgatttaaaaaagaattcaGAAGTCAAAACCGAACAATGTACAAATGAACCAAATAGTaaagaaattgaacaaaacttACTATCAGACTTGGACGACGATGATGATATATGGTCAGAAGACAGCTTTAAAGTGACTGATCATTTAAACGAAAGCGACAGTGAAAGTAACAGTGATAAAGAATCGCCTGCAACACGACGACCAAAACGGcaagtaactaaaaaaaatgaaaagaaacgCAAAGACAAACCGATCTCCGAATATTTTTCAATGGACTGTGAACTGTGTTCGTTGACATTAGATTCATTtcgaaatttacaattacactATAGAACCGAGCATAAAATTAAAGGGTACGTGCGATGTTGTAgtcgtaaatatataaaacgtgTCTACATCCTTGAACATTTACGACGCCATTTGAATCCCGAAACATTCAGATGCGATATATGTAACAAAAATTTTGCAGCCAAACGATGTTTACAGCTTCATATGCGCGGTCATATACCCTCAGAAGAGCGGCCGTTTAAATGCACTGAATGTCCCAAGACTTatgttatttcaaatttactaAAACGTCATTTAGAAACACATGCAACCGAACGAAAATTTGTATGCGGTGAGTGTGGGAAATCTTATGTCACGGAACTTCAACTTAAATCTCATCAACGCAGTATGCATAGTGAGGCCAATATTCATATTTGTGATGTATGCGCAAAACCTTTTCGTAGTAAAGACGTTTTTGAGAAGCATCATAAATCGGTACATGGGAAAGTACCGCTTCCGAAAGTGCAATGTAAAGTATGTGGTTCATGGGTTAAACATAAATACTACCTTAAGCAACATATGGCACGGCATGCCGATAGCAATACAACTTTCCCGTGTAATATTTGTGGAAAATCTGCTCCGAACATCCGTGCACTTCAAAGTCATATGCGCGTCGTGCATACTGAAAAAATGTACGACTGTAATTGGTGTGACAAAACATTTAAACGATCGATCAGCTTGAAGGAGCATTTGGCATCACATACAGGTGTAATTTTGTATTCGTGTACTTACTGCCCGAAAACGTTCAATTCATCGGcaaatatgtatacacacaGAAAAAAAAGTCACGTAAAAGAATGGAAAGAACAGAAATTAGAGAAACTTAAAGGGGCTCTTACCACAGAATACGCCGATAATAGCATCGAGACTGTTCGAGAAGGCTTCGCGTGCTGCATTAATGTGGTAGATTGCTGGATCAAAGTGTCAGATTTTCATATAtactatttaaaagtttataatatCCACTGCGAGTTGCTTGTAAAGGTAGATCAAGGCGTTAAACTGGAGGAAATAGATGAGAAACAGAACTCGAACGAAAATGAAGTAGAATTAGTAACcgatttaaaaaagaattcaGAAGTCAAAACCGAACAATGTACAAATGAACCAAATAGTaaagaaattgaacaaaacttACTATCAGACTTGGACGACGATGATGATATATGGTCAGAAGACAGCTTTAAAGTGACTGATCATTTAAACGAAAGCGACAGTGAAAGTAACAGTGATAAAGAATCGCCTGCAACACGACGACCAAAACGGcaagtaactaaaaaaaatgaaaagaaacgCAAAGACAAACCGATCTCCGAATATTTTTCAATGGACTGTGAACTGTGTTCGTTGACATTAGATTCATTtcgaaatttacaattacactATAGAACCGAGCATAAAATTAAAGGGTACGTGCGATGTTGTAgtcgtaaatatataaaacgtgTCTACATCCTTGAACATTTACGACGCCATTTGAATCCCGAAACATTCAGATGCGATATATGTAACAAAAATTTTGCAGCCAAACGATGTTTACAGCTTCATATGCGCGGTCATATACCCTCAGAAGAGCGGCCGTTTAAATGCACTGAATGTCCCAAGACTTatgttatttcaaatttactaAAACGTCATTTAGAAACACATGCAACCGAACGAAAATTTGTATGCGGTGAGTGTGGGAAATCTTATGTCACGGAACTTCAACTTAAATCTCATCAACGCAGTATGCATAGTGAGGCCAATATTCATATTTGTGATGTATGCGCAAAACCTTTTCGTAGTAAAGACGTTTTTGAGAAGCATCATAAATCGGTACATGGGAAAGTACCGCTTCCGAAAGTGCAATGTAAAGTATGTGGTTCATGGGTTAAACATAAATACTACCTTAAGCAACATATGGCACGGCATGCCGATAGCAATACAACTTTCCCGTGTAATATTTGTGGAAAATCTGCTCCGAACATCCGTGCACTTCAAAGTCATATGCGCGTCGTGCATACTGAAAAAATGTACGACTGTAATTGGTGTGACAAAACATTTAAACGATCGATCAGCTTGAAGGAGCATTTGGCATCACATACAGGTGTAATTTTGTATTCGTGTACTTACTGCCCGAAAACGTTCAATTCATCGGcaaatatgtatacacacaGAAAAAAAAGTCACGTAAAAGAATGGAAAGAACAGAAATTAGAGAAACTTAAAGGGGCTCTTACCACAGAATAG
Protein Sequence
MDTNLSQCRLCLSQSPSFLNIFTETIDDKPIASILTQHFWFEVNEDDSSKYICQDCWIKVSDFHIYYLKVYNIHCELLVKVDQGVKLEEIDEKQNSNENEVELVTDLKKNSEVKTEQCTNEPNSKEIEQNLLSDLDDDDDIWSEDSFKVTDHLNESDSESNSDKESPATRRPKRQVTKKNEKKRKDKPISEYFSMDCELCSLTLDSFRNLQLHYRTEHKIKGYVRCCSRKYIKRVYILEHLRRHLNPETFRCDICNKNFAAKRCLQLHMRGHIPSEERPFKCTECPKTYVISNLLKRHLETHATERKFVCGECGKSYVTELQLKSHQRSMHSEANIHICDVCAKPFRSKDVFEKHHKSVHGKVPLPKVQCKVCGSWVKHKYYLKQHMARHADSNTTFPCNICGKSAPNIRALQSHMRVVHTEKMYDCNWCDKTFKRSISLKEHLASHTGVILYSCTYCPKTFNSSANMYTHRKKSHVKEWKEQKLEKLKGALTTEYADNSIETVREGFACCINVVDCWIKVSDFHIYYLKVYNIHCELLVKVDQGVKLEEIDEKQNSNENEVELVTDLKKNSEVKTEQCTNEPNSKEIEQNLLSDLDDDDDIWSEDSFKVTDHLNESDSESNSDKESPATRRPKRQVTKKNEKKRKDKPISEYFSMDCELCSLTLDSFRNLQLHYRTEHKIKGYVRCCSRKYIKRVYILEHLRRHLNPETFRCDICNKNFAAKRCLQLHMRGHIPSEERPFKCTECPKTYVISNLLKRHLETHATERKFVCGECGKSYVTELQLKSHQRSMHSEANIHICDVCAKPFRSKDVFEKHHKSVHGKVPLPKVQCKVCGSWVKHKYYLKQHMARHADSNTTFPCNICGKSAPNIRALQSHMRVVHTEKMYDCNWCDKTFKRSISLKEHLASHTGVILYSCTYCPKTFNSSANMYTHRKKSHVKEWKEQKLEKLKGALTTE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-