Tbis007872.1
Basic Information
- Insect
- Tineola bisselliella
- Gene Symbol
- ZEB1
- Assembly
- GCA_028551675.1
- Location
- JAPWLS010001512.1:9618-15373[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.0065 0.35 11.4 1.1 2 23 26 47 25 47 0.97 2 14 0.0013 0.068 13.6 1.4 2 23 83 105 82 105 0.95 3 14 0.0013 0.071 13.6 0.3 1 23 110 134 110 134 0.90 4 14 0.044 2.4 8.8 0.1 1 23 168 190 168 190 0.91 5 14 0.0035 0.19 12.2 0.2 2 23 217 239 216 239 0.94 6 14 1.8 98 3.7 0.6 1 13 245 257 245 263 0.86 7 14 8e-06 0.00044 20.5 0.1 1 23 273 296 273 296 0.98 8 14 0.0093 0.51 10.9 0.4 1 23 306 329 306 329 0.94 9 14 0.0033 0.18 12.3 0.0 3 23 336 358 335 358 0.89 10 14 0.58 32 5.2 2.2 2 23 365 386 364 386 0.95 11 14 0.0017 0.09 13.3 0.5 1 23 391 413 391 413 0.96 12 14 1.7e-05 0.00093 19.5 2.6 1 23 419 441 419 441 0.97 13 14 8.4e-05 0.0045 17.3 1.1 2 23 447 468 446 468 0.97 14 14 4.1e-05 0.0022 18.3 0.4 1 23 474 497 474 497 0.97
Sequence Information
- Coding Sequence
- ATGGCTACCCGTAAACCAAAAAACGACGGTAAAACGAGCAAAACAAGCACTTGCATCGAACAACTCGGCGGCATCAAATGCAACGTTTGCGATGCGGTTTTACAAACAAAATTCAATTTCGATCGTCATTATAAGAAACATGGACATGAAAACATCGTGTACACATGCCTGGCTTGCCGCGCCGAGATAGCTTCCTACAAGACTTTCATTGACCACTGCTACAGGCATACCCTCAAATCAAGATTGGAATGCCAGATTTGCAAAAAACATTATTCAAAATCTCAAGCACTACTTGATCATTTGAAAAATATACATGGATTGGGTCAATATGTCTGTCCGTCGCCATGTAATCAAGTCTTCAACAATTTGAGCGAATTTAAAAAGCACATGGACGACACGCACAAGAAGATCAACAAAACACAGAATTGTGTGTTATGTCAGACCGAGTTGCCCACCCAGGAGTCCTGCTTGGAGCATCTGGACGCACACGTGGAGTTCATATTCAGTTGCCCGATCTGCGGAGTGCAGTTCGGTGATAGGGACGATGCACCTGAGCACTTGCATACGCATTTCCAAGATGAAATACTGAATCTACATGAGTTAACCAAATACGAGGTTGCTTACACACCCGGTAACCCAGTACAGATATCATGTGGCGTATGCAGGGTGGCATTCAAGACTAAGGCAGATTTCGAAGCGCATTACACTTCCCAGCACGACACTACGATAACCTACACATGCGCCGTTTGCTGGAAAAATTACAAACAATATAACATATTTAGCAATCATTGCTACAATCATCTTGTTAAAGGGAAATTTAAATGTGACGTCTGCCAGAAGACATTCCCCCGTCTGCCAATGTTAGTAGTTCACATGGAGACCGTACATATATCTGCAGTCAACAATGAGAAGCCGTTCGAATGTGTCGAGTGTAAGCAGAGGTTCTCAATAGGGAAATCTCTTAAAGCACATTTGCAAGATAATCATGGTGTCTCTTATCAGATTTGCTCTTTTCCCGGTTGCGGAAAAATGTTCGATTCCCCTACAGCTCTAATATCCCATGAAATAGAACATCGCAGTAGACCGCAACAGCGTTGCAGCAACTGTGGTCTACTATTCAAAAACCTGTTCGCCTGCTACAAGCACATGGACGTACACAAAATTATCAAATTTAATTGCCCAATCTGTGAACGCAAGTATTCCGAGAAGTATTTAATCGTGAAGCATTTGAAGGATCATTACCAGGGCGATATGCATGTTTGTCAGAAATGCGGGAAGGTGTATAATAGACGATACCGTTTGATGCAGCATATCAAGATACACACTCAAGAGACGTTGAGTTGTTCCTACTGCGAGAAGAAGTTTTCAACGAGGCCCCGCTTGAACGATCATGTTAACACGCATACTAAAGAAACACCCTACAAATGCTTGGTTTGTCCAAAGAGGTTCCCTTCAGAATCGGGTTGGCGTAAACATTTGAAAAATCTACACAACGTAACTTCAATTAAGAAGACCGATATGTTTGGTGTGAATAGCATTGGAGATATAGGTCCTGGAACAGATGATGCGATGCCATGTGATGATGAATTCAACATATTGGACACCGATGATAAGATTGTCGATGAAAGCGAAGAGGTCGTCGAGATAAATGCAATAGCCGAGACCATAGGTGCAGAGTTGATGGAACCGGTGGAAAGCGAATGTATTCTTGATTTAGATGCAAGAAAGTACGATGAAGATGAACCGTCCGAAGCAAAGGAGGAGCCCGCCGAGGAGATGCCCAATTTCATAGACACGTCATGCGAAACGAGCTACGGTAACCAAGTTGTTTATCACACAGTGTATCCGACGAAGATTATGGAGAACGTCACTTTTAACGACAATGATTATCAAACTGATTACGAAATGGTATTGCCTTACGCTGTACTTTAA
- Protein Sequence
- MATRKPKNDGKTSKTSTCIEQLGGIKCNVCDAVLQTKFNFDRHYKKHGHENIVYTCLACRAEIASYKTFIDHCYRHTLKSRLECQICKKHYSKSQALLDHLKNIHGLGQYVCPSPCNQVFNNLSEFKKHMDDTHKKINKTQNCVLCQTELPTQESCLEHLDAHVEFIFSCPICGVQFGDRDDAPEHLHTHFQDEILNLHELTKYEVAYTPGNPVQISCGVCRVAFKTKADFEAHYTSQHDTTITYTCAVCWKNYKQYNIFSNHCYNHLVKGKFKCDVCQKTFPRLPMLVVHMETVHISAVNNEKPFECVECKQRFSIGKSLKAHLQDNHGVSYQICSFPGCGKMFDSPTALISHEIEHRSRPQQRCSNCGLLFKNLFACYKHMDVHKIIKFNCPICERKYSEKYLIVKHLKDHYQGDMHVCQKCGKVYNRRYRLMQHIKIHTQETLSCSYCEKKFSTRPRLNDHVNTHTKETPYKCLVCPKRFPSESGWRKHLKNLHNVTSIKKTDMFGVNSIGDIGPGTDDAMPCDDEFNILDTDDKIVDESEEVVEINAIAETIGAELMEPVESECILDLDARKYDEDEPSEAKEEPAEEMPNFIDTSCETSYGNQVVYHTVYPTKIMENVTFNDNDYQTDYEMVLPYAVL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -