Basic Information

Insect: Tinea pellionella
Gene Symbol: topi
Assembly: GCA_948150575.1
Location: OX411265.1:4491549-4501230[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.015 0.8 10.3 4.1 3 23 79 99 77 99 0.96

2 11 0.00043 0.024 15.1 0.2 2 23 135 157 134 157 0.96

3 11 1.3e-06 7.2e-05 23.0 1.6 1 23 163 185 163 185 0.98

4 11 1.5e-06 8.3e-05 22.8 2.8 1 23 191 213 191 213 0.98

5 11 0.053 3 8.5 0.8 1 21 219 239 219 240 0.94

6 11 0.042 2.3 8.8 1.5 3 19 263 279 262 284 0.92

7 11 2.7e-05 0.0015 18.9 3.6 1 23 573 595 573 595 0.98

8 11 9e-06 0.0005 20.4 2.5 1 23 602 625 602 625 0.97

9 11 0.05 2.7 8.6 1.3 1 23 633 656 633 656 0.95

10 11 0.0084 0.46 11.0 2.5 1 23 662 686 662 686 0.96

11 11 7e-07 3.9e-05 23.9 1.0 1 21 692 712 692 713 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.015	0.8	10.3	4.1	3	23	79	99	77	99	0.96
2	11	0.00043	0.024	15.1	0.2	2	23	135	157	134	157	0.96
3	11	1.3e-06	7.2e-05	23.0	1.6	1	23	163	185	163	185	0.98
4	11	1.5e-06	8.3e-05	22.8	2.8	1	23	191	213	191	213	0.98
5	11	0.053	3	8.5	0.8	1	21	219	239	219	240	0.94
6	11	0.042	2.3	8.8	1.5	3	19	263	279	262	284	0.92
7	11	2.7e-05	0.0015	18.9	3.6	1	23	573	595	573	595	0.98
8	11	9e-06	0.0005	20.4	2.5	1	23	602	625	602	625	0.97
9	11	0.05	2.7	8.6	1.3	1	23	633	656	633	656	0.95
10	11	0.0084	0.46	11.0	2.5	1	23	662	686	662	686	0.96
11	11	7e-07	3.9e-05	23.9	1.0	1	21	692	712	692	713	0.96

Sequence Information

Coding Sequence: ATGGATACTAGTTTGTCATATTTTGTTCTATCGTATGAGGGTTCGGGGACAACAGAAAGTGGATATAACCTAAAGAATGTGACACACGAAGATTCTCTTGATAATGTGTTAAATCAGCCTCCAAGGCCGCCGTCACCCTTTCTTCAACCCGATGATGTTTTAGATGAATTGTTGTCAACAGCTGATGCACATCATTTAGGTGAAACACCACGTAATGTGACTCAATCTATGTGCTGTCATATTTGTAATAAAAGTTTTGATAAACTTTGGAAGTATTATGGGCATCTGAGAGTGCATTCTAAAGATAATTTGTGGTTTTGTGATAAATGTCCAGATGTAAAATATTCAACAAAGAAACAACTTGATAAGCACTGCATAGAAACTCATAATAAGGCCTCCGTCACATGTTCATATTGTCCTATGGGGTTTTCTACAGCATGGAGATTACAACAACACATACTATCAAAACATATTAATTATAGATCTCACAAATGCGTTCAGTGTGATAAAGCATTTGTCAAGCCATCCGATCTTAAGAAACATCAAGAAACACATAGTGAAGTAAGAAAGTATGCTTGTTCACACTGTACAGCTAAATTTAAAGATAAATCTAATTTGAAAAGGCATATATTAATGCATACAGGCACTAAAAAATATGTTTGTTCTGCCTGTGGACATAAATACCAACAGATAGCATCATTAAACCGTCACAAGAAGAAATGTTTGCCAAAAACAGAGAGTTTGGACAAGAATAATAGTACACAAGCAAAGACGAGACAAAATCATTGTAGAGTATGTGGCATGACGTTTATTTATAAAAGTGCCCTGTTGGAACATTGTGTCAGAGAGCACACAAATCCAAAAGAAGATACACATGAAGACAAACATGTAGAACAGACACGTTTACATGATGAAAACACAGTTGATGATTTAGATGAAATATTATCGGCTGACAATGATTATTCAACAATTGATTCAAACGTAATAACAAATGATTGTGATATCACAATATTTAATCAAATGCAAGCCCAACCTTTAGACAATAATCCTGATAGCCTATTACAAATTGAATTCTTAAAAGAAATGAACCAACTTCACACTATAGATGACGAGCTATTTTACAATGATATGATGGATTTCGATTTTCAACCGAGTAACTTTGGCAATGATTATGATTATGGTAACCCATCTGATGCTAATTCCGGTATACTATTCGATTTTGCTGATAACGGTCGGAGTTTGGACCAAGATTTGATGAGTGCGTTCTTACATCTTAAATCTAAAGATTTGCCTGACGAATTATTGAACGTCCCTGAAGGGCTGATTAAGGACGCCGTCTTACCTGATATTAAGGAAGAGAACAAAGATGCGATAGAGAATCCTGTATCGGTAAATGATTGTGCTACAATATTCGAAAGTGATGTAGATTTGGAGGAGAGTTCGAATCTCGCAGCAAATTTGAATCAATTAATCGGAGAGAATAATGTCCAATACATTTCTACGGAGGATGATGATACGTTCATCATAAGTTTAAATAGTACTATAGATGCTGAACAATTAACTGATATGTTGAATATTGGTATTGAGTATGTAGATGAAAATAAAGCTGATATGGAAAGAAAAGTCCCTGAAGCGGTGAAGACTGAAACAGAACAACTAGAGGAAGAGAAGACTGAAAAGGAAGAAATAAAAAATAAGGTCAAAAGACCGGCCGTATTTATTTGTAAGACTTGTAAGAAGAAGTTTAATAAGAAGGATAATTATAAATCTCATATAGCTACTCACGAGCCATCACTGCGTCGCCACGTATGCCCAATATGCCGTGAAAGGTTTAGTTATAGATCTACATTGAACAAGCATGTCCGTTCGCGACACATACCACGCGTCGAGCCTGCTCATAATTGTGGAATCTGTCATAAACAGTATAAAGCCGCTTGGCTGGTTAAGAATCACATAGAACGCGATCACGAAGGGATAACCCCTTTCAGTTGCAATTTTGAAGGTTGTAATAGGAAGTTTTATAAACAATTTGATCTTGTTATACATAAAAGGTTTCATACTGGTGATCGTGCGTACGAGTGTGATATTTGCAACAAGAAGTTTCCGCACGCGTCACATCTCAAGCGTCATGTCAGGGCTACTGATTGTACTAAACGATTAAAAAAGAACATATCGATGAAAAATACTGCTGGTAGAAAATCAGCGACAAAACCAGTTATACCAGTTTACCAAATGGTATCTAATACAACGGCGACGCTTATGCCCGTTTTCACCAATAAACTTTCAACGCGCACTCACTTAGGCGTTCCTTTGACTAAAGGTGCCCCTAAAAGATAG
Protein Sequence: MDTSLSYFVLSYEGSGTTESGYNLKNVTHEDSLDNVLNQPPRPPSPFLQPDDVLDELLSTADAHHLGETPRNVTQSMCCHICNKSFDKLWKYYGHLRVHSKDNLWFCDKCPDVKYSTKKQLDKHCIETHNKASVTCSYCPMGFSTAWRLQQHILSKHINYRSHKCVQCDKAFVKPSDLKKHQETHSEVRKYACSHCTAKFKDKSNLKRHILMHTGTKKYVCSACGHKYQQIASLNRHKKKCLPKTESLDKNNSTQAKTRQNHCRVCGMTFIYKSALLEHCVREHTNPKEDTHEDKHVEQTRLHDENTVDDLDEILSADNDYSTIDSNVITNDCDITIFNQMQAQPLDNNPDSLLQIEFLKEMNQLHTIDDELFYNDMMDFDFQPSNFGNDYDYGNPSDANSGILFDFADNGRSLDQDLMSAFLHLKSKDLPDELLNVPEGLIKDAVLPDIKEENKDAIENPVSVNDCATIFESDVDLEESSNLAANLNQLIGENNVQYISTEDDDTFIISLNSTIDAEQLTDMLNIGIEYVDENKADMERKVPEAVKTETEQLEEEKTEKEEIKNKVKRPAVFICKTCKKKFNKKDNYKSHIATHEPSLRRHVCPICRERFSYRSTLNKHVRSRHIPRVEPAHNCGICHKQYKAAWLVKNHIERDHEGITPFSCNFEGCNRKFYKQFDLVIHKRFHTGDRAYECDICNKKFPHASHLKRHVRATDCTKRLKKNISMKNTAGRKSATKPVIPVYQMVSNTTATLMPVFTNKLSTRTHLGVPLTKGAPKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01453472;
90% Identity: -
80% Identity: -