Tshe003281.1
Basic Information
- Insect
- Timema shepardi
- Gene Symbol
- ken
- Assembly
- GCA_902151425.1
- Location
- CABFVX010000137.1:30613-46073[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 9 2.5e+03 1.7 0.0 10 23 206 219 197 219 0.85 2 10 0.46 1.3e+02 5.7 0.8 5 23 257 275 255 275 0.94 3 10 0.00041 0.11 15.4 1.0 1 23 281 304 281 304 0.96 4 10 3.2e-05 0.0086 18.9 0.1 1 23 356 378 356 378 0.98 5 10 2e-05 0.0054 19.5 2.6 1 23 384 407 384 407 0.96 6 10 2e-05 0.0055 19.5 0.5 2 23 414 435 413 435 0.97 7 10 2.8e-05 0.0077 19.0 1.4 1 23 441 463 441 463 0.97 8 10 0.02 5.5 10.0 7.6 1 23 469 491 469 491 0.98 9 10 0.00026 0.07 16.0 1.2 1 23 497 519 497 519 0.95 10 10 0.00032 0.087 15.7 5.7 1 23 525 547 525 548 0.95
Sequence Information
- Coding Sequence
- ATGCACAGGAGGTTTATGCACAGGGCTGTCTCTGGGCAGTGCACACAAAAGCAATGCACACTAAGGAGATTCATCTCGGACATCAGCGACCCTATAATCCAGACAGTGTGCAAGCAGGAGATTCACTCGGACATCAGCAACCCTATAATCCAGGCAGTGCGCAAGCAGGAGATTCATTCGGACATCAGCGACCCTATAATCCAGGCAGTGCTCAAGCAGGAGATTCACTCGGACATCAGCGACCCTATAATCCAGACAGTGTGCAAGCAGGAGATTCATTCGGACATCAGCGACCCTATAATCCAGACAGTGTGCAAGCAGGAGATTCACTCGGACATCAGCAACCCTATAATCCAGGCAGTGCTCAAGCAGGAGATTCACTCGGACATCAGCGACCCTATAATCCAGGCAGTGCTCAAGCAGGAGATTCACTCGGACATCAGCGACCCTATAATCCAGGCAGTGCACAAGCAGGAGATTCACTCGGACATCAGTGACCCTATAATCCAGGCAGTGCACATGCATGAGATACACCTCGACATAAGTGCTTATAGCCAGGTGGTTCACATGCAGGAAAAACACCCCATGTACGAATGCAACTTGTATGGTCTAATCCTGACAAATCGAGACAATATGAAACTCCACCTGGAAGTGCACAACAATCCTAAATGGCCCTCAAGTGACGATTTGGTTGAATCTGATCACGGCATATCTAGTAAACGGGTTCTGGAAGAACCCTCTGATGATGACGACTCAAAGAAACCCTTCACCTGCCACATGTGCATCAAGAGAAAGGGGGCTGTAGACAACCACATGCGAATACATACTGGGGAGAAACCTTACACTTGCAACATTTGTATGAAGAACTTTATGGTGAGGTCGACATTGACTCGCCACCTTAAGGAGGTGCATGAGCACCAGCAAAAACGCATCTGTAAGGTGTGTGGGTGGAAACAGACCCATTTGACAACACCGTATGGTGTATTGCATGAAGCTGACATTCCTAAATGGTTCAAAAATGAAGAGTCCGAGTCGGAGATCGTTGAGATGCCCGATCGGCCCATCTTTGAGTGTGATTACTGTGGTAAGATTTTGGCGTCAAGGGAGAACATAAGGGTGCATCTCAGGATCCACACTGGGGAACGCCCATTCACATGCCACGTGTGCGGCAAGTGTTTCAAGGCACCATCTGGCATCAAGCGCCATCTCAAGGAGGTTCACGAGGGGGTCAAGGACCAAACATGTGAAGTGTGCAGTCGCTCATTTGCTAACAGACGAACACTTGAGGACCATTTACGCATTCACAGCGGGGAGCGTCCATTCGTGTGTGCGGCCTGCGGGAAGACATTTAAGACAAAGGCATCGTTGCATGTCCACAACCGCAGCCACAGCGATGTTTACCCATTCCCATGCAGCCAGTGCAACTGCAAATTTCACACTCAACACAGTTTGTCAGTTCATCTGCTTCGTCACACTGGTGAGAAACCGCATGCTTGTAATGTGTGTGGCCGTAGGTTCCGGATCAAGTACGAGCTCGGGCGACATAAGCTTGTTCATTCTGAGTACAAACCGTTTGTATGCATGGTGTGTGGACACTCGTTCAGACAGAGGAAGTATCTGATGAATCACAACAAGACCCATCACAGAGAATGTTTCACAGAACTCATTGTTTGCTGA
- Protein Sequence
- MHRRFMHRAVSGQCTQKQCTLRRFISDISDPIIQTVCKQEIHSDISNPIIQAVRKQEIHSDISDPIIQAVLKQEIHSDISDPIIQTVCKQEIHSDISDPIIQTVCKQEIHSDISNPIIQAVLKQEIHSDISDPIIQAVLKQEIHSDISDPIIQAVHKQEIHSDISDPIIQAVHMHEIHLDISAYSQVVHMQEKHPMYECNLYGLILTNRDNMKLHLEVHNNPKWPSSDDLVESDHGISSKRVLEEPSDDDDSKKPFTCHMCIKRKGAVDNHMRIHTGEKPYTCNICMKNFMVRSTLTRHLKEVHEHQQKRICKVCGWKQTHLTTPYGVLHEADIPKWFKNEESESEIVEMPDRPIFECDYCGKILASRENIRVHLRIHTGERPFTCHVCGKCFKAPSGIKRHLKEVHEGVKDQTCEVCSRSFANRRTLEDHLRIHSGERPFVCAACGKTFKTKASLHVHNRSHSDVYPFPCSQCNCKFHTQHSLSVHLLRHTGEKPHACNVCGRRFRIKYELGRHKLVHSEYKPFVCMVCGHSFRQRKYLMNHNKTHHRECFTELIVC*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -