Tshe014433.1
Basic Information
- Insect
- Timema shepardi
- Gene Symbol
- -
- Assembly
- GCA_902151425.1
- Location
- CABFVX010000937.1:137206-175446[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 5 1.4e+03 2.5 0.5 3 23 24 44 22 44 0.85 2 17 0.0017 0.46 13.4 0.6 1 23 361 383 361 383 0.98 3 17 0.28 77 6.4 1.1 1 19 387 405 387 407 0.92 4 17 0.15 41 7.3 2.5 2 23 416 437 415 437 0.95 5 17 0.2 53 6.9 0.7 2 21 442 461 441 466 0.91 6 17 0.0022 0.59 13.1 0.3 3 23 473 493 472 493 0.98 7 17 0.051 14 8.8 2.4 3 23 533 553 532 553 0.97 8 17 0.17 46 7.1 1.9 2 20 558 576 557 577 0.87 9 17 0.0053 1.5 11.8 0.1 2 23 583 603 582 603 0.96 10 17 0.5 1.4e+02 5.7 0.8 1 17 608 624 608 625 0.89 11 17 0.0031 0.85 12.6 5.1 2 23 654 675 653 675 0.95 12 17 0.00017 0.047 16.5 1.9 1 23 680 702 680 702 0.97 13 17 7e-05 0.019 17.8 0.5 1 23 707 729 707 729 0.96 14 17 1.5e-05 0.0041 19.9 0.3 1 23 735 757 735 757 0.97 15 17 0.00035 0.095 15.6 0.8 2 23 766 787 765 787 0.95 16 17 2.9e-05 0.0078 19.0 7.0 1 23 793 816 793 816 0.97 17 17 0.0026 0.7 12.9 4.2 1 23 821 844 821 844 0.97
Sequence Information
- Coding Sequence
- ATGATGAAGGTAGTAGCTGAGCTGCCTGCTGAGAAGCTTGGCGCACGCAAAGTTCAGGACCAATGGTGCTGTAAGCTGTGTGGCTACCAAGAGGCGAGTGTGGCAGTGTATGCCAAACACATGAGGAGTCATTTCAAGCCGCTCCTTAGATCCACAGACAAGTTATACTGCCATGCGTGTAGGCTGCAGTTCAACAACGAGAAGgCAATGTTGAAGCACAAGGTAGATTGCCATGGACTTACCCTGAAACGACCGCACCTTATGGAAGTGTTACAAGGGACACAAGACCCTGAGGGGCCACGCCCTACCTCCTACACAACCCAAGACACCTGTCAGgCCCTGTTCCCTGTCCCTGAACAGGAACAGATGTTTCAGAATCAGTCCTTGAGCAGTCTGCTACAAGAAGGCCACAACGAAGCCCTCAAGTCACTCCTAGACCAATACCAAGTCCCTACTCAGAGAGAAATGCAATTCTCTGAGAAGACGCTGCCAGGTGACCCCAAGGAACCTTTTGGCTCACCAGGTTTCATACCTGACCTAGTAGATGCCGCCAACATGGATGCTGTTATGGAGAAGAGCTTCAACCCCTCAGAGTCAAGCAACATTCTCACTAATTTTGATCCCCGGAATGAGCCATCTCTAGGGGGATTGATTGGAACAGGCTCCAAGGCTGAGGGTACGAATAGTACATCTGACGTACATGTGATGATAATGTTGGATCAGGCCAAGTGTGATGAGGTTTACGGTCTTAGTGGTGGCAGGGACCGTGGAGATTGTGGCTTGTCGTACAAGATGGAGGGTTCGGGAGACAGTCGGGACGAACTCAGGACTCCGGTGGGCTTTGGTCTGATTGACGGTTCTGACAGTGCAAGCTGTGATAAGACCAGTAACAAGCTGGATCTGAACGGGGGCCAGGATGCTCTCCTGTCCCTGGTGCCACACAAGGACTTCAGCATCGGGAGTGATGCAGTGGACAAGACACAGGCTTTAAGTGTGGCTTTGATGGACGCTGTGGACGGAATCAATCAACAGGCAGGTAATGGTACTCCGGTGGACCAGTTATCTGACAAGGGACCTCCCTTCATCTGTGACATCTGTGACAAAGAATTTCTAAGAGTGATCTATCTGTACAGACACCTGCGAAAACACACGGGAGAGTTCACCTGCATCACCTGTAAGATGGTGTTTGCACGCAAGGAGTCGCTGCTGACCCATTCTTGTTTCTCTAAGGACCTTCCCCCTTTGACCTGTCCCCATTGTTTCAAGACCTTTCTGATCATGAAGCTGCTCAAGAAACACCTCGCCAAACACACCGGTAAATGGACATGTAAAGCTTGCAAACGTATCTATAGCTCCAAGCCGGCATTGGCCCAACACAAGTGTTCGCAAGCGCCACACGCCAACAAACTCGCTCTGTGCCCGGTGTGCAACAAAGCATTCCAGAAAATCCTGTGGCTACAGAAACACCTACGCCTTCATGCCGAAACTGTTCCCTGTGACACCTGCGGGAAAAAGGTCTGCCTGGGACCAGAGACAGACACTCATAGCGCCTACTGTGTGCAGGGTAAGCTGCTGGAAGCCATTGGTCAGGCTTGCTGCCCTCTATGCAAGATCACCTTCTCGGAGCTGGAGGCATACAGGCAACATGTCCACATGCACACCCACCCATTGAAATGTGAGGAGTGCGGCCAGCGCTTCAAATTCAACAAGGGTCGCAGGCTTCATGTTTGCCCCGGAGAACCTTGGGTATGCGACATGTGTTCTGAGTCCTTCACGCTTGCCAACCTCACCCTCCACCAGGCAAGCCACGGCATTCCACCTCATCACTGCTATGAGTGCGGCCGAGACTACTACCGACAGGAAAACTACCTGAAGTGCTGTGTGGGCCCCCCAAGGAAGGTCAAGATGAGGGAGACCAACAATAACAAGGATACAGCTTCCACAAAATCTGAGAGCTGTGTATGTCACGTGTGTGGAGAGCTGTTCAAGACCACATCGAGTCTCAGGCTACACATATCCCATCATAAGGAGCAGCAGTACTCATGCGAGATATGTCCTAAACGCTTTTATCGTAAGGATGTCCTGCAGGAACACCACTTTGTACATCAGGAGCCCAAGTTCCCCTGCACAATATGCAACAAGATGCTCAAGTCAAGCAAGTCGCTCAACACTCACATGGTGTGGCACTTGGGCAAGAAGCGTTACTCATGCTCTGATTGTGGACGGGAGTTCTTCCAGAAGGGCAATTTGTTGAACCATGCTGAAATGCACAAGGACGGCCACAGGGCTTTGCTCGAGTGTACCTTCTGCAGCAAGAGTTTCATCAACAAGAATGGGTTTGCACGCCACCAACTGGAGCACACTCAAGCGCACATCTACAAGTGCACACATTGCAGCAAGTCCTTTATCAAGAAACATATGTTGACCTCACACATGCGGTTGAGCCACAGCAACCACAGCTTTGAGTGTCCGTACTGTCGCATGTCCATTCGCCACAAGACAAGCTTCAGGAGACATCTGCAGAGCCGTCATGAGAATGTCAGGGATGAGTGGAACACTGACATGTTCTGGGAATCCTTCCTGTCCCCACCAACGCAGGAACAGGACCAGGTATGCGAGGTGTTGTTGACAGTACCCGGGGTCCAACTCCCTGGAGGAGAACAGGACAAGAAAGAGTCTGCTCTCTCACATGACTCCTTGCAGCCTCCTGACCCATTACTCGCCATGCAGGATCCCCCTGTGTCTGTCTGTAACACGTATATACTTGAGGATGGAACCATCATCCAGCCGGAAGGAGGGGAGGGAGATATTCTTCTCTACGTCCTCGACACCAACCCTACCAACCAAGCTTTCTAA
- Protein Sequence
- MMKVVAELPAEKLGARKVQDQWCCKLCGYQEASVAVYAKHMRSHFKPLLRSTDKLYCHACRLQFNNEKAMLKHKVDCHGLTLKRPHLMEVLQGTQDPEGPRPTSYTTQDTCQALFPVPEQEQMFQNQSLSSLLQEGHNEALKSLLDQYQVPTQREMQFSEKTLPGDPKEPFGSPGFIPDLVDAANMDAVMEKSFNPSESSNILTNFDPRNEPSLGGLIGTGSKAEGTNSTSDVHVMIMLDQAKCDEVYGLSGGRDRGDCGLSYKMEGSGDSRDELRTPVGFGLIDGSDSASCDKTSNKLDLNGGQDALLSLVPHKDFSIGSDAVDKTQALSVALMDAVDGINQQAGNGTPVDQLSDKGPPFICDICDKEFLRVIYLYRHLRKHTGEFTCITCKMVFARKESLLTHSCFSKDLPPLTCPHCFKTFLIMKLLKKHLAKHTGKWTCKACKRIYSSKPALAQHKCSQAPHANKLALCPVCNKAFQKILWLQKHLRLHAETVPCDTCGKKVCLGPETDTHSAYCVQGKLLEAIGQACCPLCKITFSELEAYRQHVHMHTHPLKCEECGQRFKFNKGRRLHVCPGEPWVCDMCSESFTLANLTLHQASHGIPPHHCYECGRDYYRQENYLKCCVGPPRKVKMRETNNNKDTASTKSESCVCHVCGELFKTTSSLRLHISHHKEQQYSCEICPKRFYRKDVLQEHHFVHQEPKFPCTICNKMLKSSKSLNTHMVWHLGKKRYSCSDCGREFFQKGNLLNHAEMHKDGHRALLECTFCSKSFINKNGFARHQLEHTQAHIYKCTHCSKSFIKKHMLTSHMRLSHSNHSFECPYCRMSIRHKTSFRRHLQSRHENVRDEWNTDMFWESFLSPPTQEQDQVCEVLLTVPGVQLPGGEQDKKESALSHDSLQPPDPLLAMQDPPVSVCNTYILEDGTIIQPEGGEGDILLYVLDTNPTNQAF*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -