Basic Information

Gene Symbol
-
Assembly
GCA_902151425.1
Location
CABFVX010000341.1:105359-126715[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 2.9 7.8e+02 3.3 0.6 1 23 236 258 236 258 0.91
2 16 1.8 5e+02 3.9 3.3 1 23 281 303 281 303 0.82
3 16 0.028 7.6 9.6 0.6 2 23 310 332 310 332 0.94
4 16 0.0039 1.1 12.3 2.1 2 20 338 356 337 358 0.93
5 16 0.00014 0.038 16.8 0.7 1 23 386 409 386 409 0.98
6 16 0.057 15 8.6 0.2 2 23 419 440 418 440 0.97
7 16 0.0055 1.5 11.8 0.5 1 23 460 482 460 482 0.98
8 16 0.044 12 9.0 0.9 2 23 489 510 488 510 0.95
9 16 0.022 6.1 9.9 1.2 1 23 529 552 529 552 0.94
10 16 0.0036 0.97 12.4 0.1 1 23 569 592 569 592 0.96
11 16 4.5e-05 0.012 18.4 0.3 1 23 597 619 597 619 0.98
12 16 1.3e-06 0.00035 23.3 1.1 1 23 625 647 625 647 0.99
13 16 0.00016 0.043 16.7 1.1 1 23 653 676 653 676 0.97
14 16 0.0075 2 11.4 0.7 1 23 682 704 682 704 0.97
15 16 1.3e-07 3.4e-05 26.4 1.7 1 23 710 732 710 732 0.98
16 16 0.00018 0.048 16.5 1.7 1 23 738 761 738 761 0.96

Sequence Information

Coding Sequence
ATGGTTGGTAAAATTGACATTGCCTCATCAGAGAATGAACATTCATCTGAGGACAATGATTtggataatttagaaaatattgatatgaGGTATCGTGAATCACTGTGCAGATTGTGTGCTTGTCATGTTGGAAATCCTGTTTACATCTTTGGGAATGCTGGAAAGAATTTGAAGTTGGCGAACATGATCAATTGTAGTCTTCCCATCAGTGTTAATATCACAGACACCTTACCTAAACAATTATGTTCATCCTGCATCGACAAACTAACAATTTGTCATAAGTTTGCAGAGTCTTGCATAGAAGCAGAGGAACGTCTAAAAGTATTATCTAAATGGTCTTCAAACAAGCTGATTGAGCCCCAAAGGATTGAGTACCCTTCAGACCATCATAACTGCCCTTTATGTGTAAATGGCACAGTAAAGGTTTTGGATAAGGCACCAAAAGAATTAGAAGATGCTGAAGAAATGGAATGCTTGGTCGACATTGCGAATTATCATTGGTGCAATCATGAGAACAAAACAGACTCTGAGGAGGATGTGGAGAATGAAAATTATTCGAATGATGATCAGCAAGGGAGCAAACCTaaagataccaattttgaagaAAGCAAAGACACGATATACATCTGCCGGATGTGTGGCGAGTTATGCTCCACtgttagttttagttttgagCATTCACTGACACACGCTGTGTCCGGTAACTATCCTTGCATCCTTTGTGATACTAATTTGATTGACAGAAGGGGacttgaaaaacattttttacaccATCGGAGTGAACAAATGACCTATGGTAGAGAACTCTCTAGAAGGGGGGAGTGGCAGAGAGACAAGACCTACAGATGCAAGATTTGTGAAAAACTGTTTTACAAAAGGGAAAGATATATTTTCCACCAGCAGTTTCATGACGGTGCCAGGGAGAATTATTGCGATATTTGTCACAAGGAGTATGGTAGTGAGTTGTTGTTGTTCCGTCATGTCAACCAAATCCATGCTAACTTAGCGTTAATTTGCCAACATTGCGGAGAAGATTTTGACTCTCAATACACACTTGAAAATCATCATTGTGATGAGAATAATGGGATGTATAAGTGTGAACAGCTGCCAAAGATGGACACTAAGGAACCTGGTCACAAATCCCCTGAAGAGATGTATGTGTGTAATTTGTGTGAAACAAACTTTGCTACCCAGAGAAAACTAAGTGGCCACATGAGGTCTCAGCATGGGCAGGTGGGATCCCAGCGGTGTATTCGCTGCAACACTTGCCAAGCCATATTCCCTGATATCAGCCAAACCATTATGCACACCAAGACACACTTCTCTGGTTCCGAAGGAGGAAGTACAAGAGTAGAAGAGGTGTGTGCCACTAAACTGTTTGTCTGTGAATACTGTGAGACTTTCTTCGCCTATCCAGAGATCCTCAATACTCATCGCAAGAGTCATACCAGCTCAAAGCCCTTCTTGTGTCGGTCATGCCCAGAGACGTTCTCTAACTTCACGCAGGCAGATGTCCACAGGCGTACACATTCAAACCCAAACCATCTTCATAACAGCAGCCATATGTTCACCATCCCTGTTGTGTTTCTCTGTGAGGTGTGCAGCCGAGGTTTCAAGCTCTGGGAGAGTTTTCACATCCACCGTTTGAGGGATCACGAGAAGCTACAGGAGTCTGGTCTTTGGTTTCAAGGGTCTGATGGGATCTATGAATGCGAACTCTGTCCCGACACTTTTGAGCAGAAGAAGCAGCTTCTTGGGCACATCAAGCTGGAGCATCTCAAGAAGAAGTTTGAGTGTGATGAATGTGGCAAGGTGTTATCTCATATTTCTGGTTTGATCATCCACCGGCGACAGCACACAGGTGAAAAACCTTATACGTGTGATGTGTGTGGGAAGTCATTTAGACAAAGTGCGGGCATGTACACCCACCGGCGCACGCACACCAAGGAGCACCCCTATTGCTGTGAGATATGCGGGCAGGGCTTTAATGTGAAAGGAGACCTTGATAACCACCGGCGCTCCAAACACACTAAAGAGCGCCCCTTCAAGTGCCCTGTCTGTCAAAAGGCATTCCTCACCTCTGGTGTTTTCTACCAGCACAGGATGATGCACGCCGGCATCAAGAAGTACCATTGTCAATACTGCGGACGTGCCTTCTCACGATGGAACGCCCTTCGTTTGCATATCCGCACGCACACAGGTGAGAAGCCTTATGTGTGTGAGGTGTGCAATCGAGCATTTGCTCAGAAGGGAGACATGAGGAAGCATTGCCGCACTCAACACCCACCAGTTCAATAG
Protein Sequence
MVGKIDIASSENEHSSEDNDLDNLENIDMRYRESLCRLCACHVGNPVYIFGNAGKNLKLANMINCSLPISVNITDTLPKQLCSSCIDKLTICHKFAESCIEAEERLKVLSKWSSNKLIEPQRIEYPSDHHNCPLCVNGTVKVLDKAPKELEDAEEMECLVDIANYHWCNHENKTDSEEDVENENYSNDDQQGSKPKDTNFEESKDTIYICRMCGELCSTVSFSFEHSLTHAVSGNYPCILCDTNLIDRRGLEKHFLHHRSEQMTYGRELSRRGEWQRDKTYRCKICEKLFYKRERYIFHQQFHDGARENYCDICHKEYGSELLLFRHVNQIHANLALICQHCGEDFDSQYTLENHHCDENNGMYKCEQLPKMDTKEPGHKSPEEMYVCNLCETNFATQRKLSGHMRSQHGQVGSQRCIRCNTCQAIFPDISQTIMHTKTHFSGSEGGSTRVEEVCATKLFVCEYCETFFAYPEILNTHRKSHTSSKPFLCRSCPETFSNFTQADVHRRTHSNPNHLHNSSHMFTIPVVFLCEVCSRGFKLWESFHIHRLRDHEKLQESGLWFQGSDGIYECELCPDTFEQKKQLLGHIKLEHLKKKFECDECGKVLSHISGLIIHRRQHTGEKPYTCDVCGKSFRQSAGMYTHRRTHTKEHPYCCEICGQGFNVKGDLDNHRRSKHTKERPFKCPVCQKAFLTSGVFYQHRMMHAGIKKYHCQYCGRAFSRWNALRLHIRTHTGEKPYVCEVCNRAFAQKGDMRKHCRTQHPPVQ*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01445890;
90% Identity
iTF_01445890;
80% Identity
-