Basic Information

Gene Symbol
-
Assembly
GCA_902151425.1
Location
CABFVX010000111.1:458981-478290[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 1.3 3.6e+02 4.3 0.1 3 23 238 258 237 258 0.97
2 16 0.0071 1.9 11.5 1.8 1 23 264 287 264 287 0.95
3 16 0.13 36 7.5 0.3 3 21 320 338 320 339 0.95
4 16 0.0019 0.51 13.3 0.1 1 20 509 528 509 530 0.94
5 16 0.00066 0.18 14.7 2.0 1 23 536 558 536 558 0.98
6 16 0.00044 0.12 15.3 1.3 3 23 568 588 566 588 0.96
7 16 4.5e-07 0.00012 24.7 2.0 1 23 594 616 594 616 0.98
8 16 0.0098 2.7 11.0 0.0 1 23 622 645 622 645 0.96
9 16 1.5e-05 0.0041 19.9 0.4 2 23 690 711 689 711 0.96
10 16 0.65 1.8e+02 5.3 0.1 2 23 720 741 719 741 0.97
11 16 3.9e-06 0.0011 21.7 0.5 1 23 773 795 773 795 0.98
12 16 5.5e-06 0.0015 21.2 0.6 1 23 801 823 801 823 0.98
13 16 0.00021 0.056 16.3 0.1 1 23 829 853 829 853 0.98
14 16 0.00096 0.26 14.2 2.3 1 23 859 881 859 881 0.97
15 16 0.00031 0.084 15.7 0.9 1 23 887 909 887 909 0.98
16 16 0.053 14 8.7 0.1 2 19 919 936 918 936 0.92

Sequence Information

Coding Sequence
ATGGCAGAAAATAGGCCTGTCCAAACCACAGCATCCACCGCTGCAGAAGAGGTCTGTCGTTTGTGTGGAAAAACCAAAGTGGATCTTGTCTCAATATATTCTGAAGAAGCCTCGGCTAAGAACATACTCCAGAAGATGAAAGACTTGCTCAATATCAATGTTACACCGCAGGATAAGCTATCGAAGCGCGTGTGTCACCCATGTGTGACCCAGCTAACCTTGTGTGATGGCATGGTAGAGTTCTTCATGAAAAACCAAGAGGTGCTCAAGAAAAAATACCCTGAAGACACACAACCAGGAGAGCTGAGCAAGGATTTGTCAACTGATGCTGATTCTGGTGAGCCAAGTGAAGCCTGTGCTGTGGATGGCGATGAAGCTACTTTAAGTCCAGTTGAAGAGCCACCAAACATAAACACTAACGCTTCTACAGACGGGCCAAGGGAAAAAATCAATGTGGAACTGTGCCGAGTTTCCTCGACAGTTTTATGTGTGTGCAGTGCTGCTAGTTTTTTCGTCCCTGCACGGACAGTTATGCGTGGTCACGGCAGCTCTCGAGGTTCTGGCCTCGAGCTCGTTGCGGTACTCTTGGTTCTGGGCTTGTTGAGAGCACGTTGGGGTTATTGTGATGCTATCACGCAGAGTCTGGGGGTGTCCATCAACCAAGATATGTTGTTTGCCCTTCATGGTCTAGATGCTACCCTACCTGTTGCTTGTGACTTCTGTGAAAGTGAATTCGATGACTTGGAGAAGTTCGACATCCATATGGCGAGCCACAAGGAGGTGCGTTTCTTCTCATGCCAACTCTGTACCAACACGTACATGTCCTGGAGCAACCTGGTGGCGCATCGCAAGGCATGCCACGGAGGCTCTGTTCTTAGCTGCGAAGAGTGCAGTGAGCGCCGCTACCATCCGGACCTTGGGCCTGTCAACTATGCTGTTGGGGACTTCCCTGTGGGGTGCGAGGAGTGCGGGGCAGGTTTCCATAGCCTTAATGAGTTGTATCGCCATTTCCGAGACCAGGCCAACCACAACACTGTTCGGCGTGTCAAAATTGCCAAGTTTGGTGTTATGGGGCTGGTATTGACAACATTTGAGATTCAGGGGCAGAATTTAGGAACCGTCCTGGCCGTCAAGAGAACGAGGCTACCGTCCAAGGGTCTTCAAAAGatcaagagcctaccgtccaaaGGCCTTCAAGAGACCAAGAGATTACCGTCCAATAGCCGTCAAGAGAACAAGAGACTTCCGTCCAAGGATCTTCAAAAGATCAAGAGACTACTGTCCAGGAGCCATCGAGAGAGTAAGAGTCTACCGTTCAAGGGTCTTCAAGAGACCAAGAGCCTATTGTCCAAGAGCCTTCAAGAGAGTAAAAGCCTACCGTCCAAGGGCCGTAAAGAGAACAAGAGCCTACCTTCCAAGGTGTGTGACGAGCCCAACTCAAAgtcaaaagaagaaaaagttgGCCAGCCCAGGCTTGCCAAACCTGTAAAGAAAAAGCCAACATTCAGGGCCATGTCTGTGCGTTTCATGTGCCCGACATGTGGAATCCAGTTTTTTACAGCGGATAAGCTCACGGAGCACCTCGCAAGGCTCCCCAAAGAGGGTTTTGTCTGTGAGACCTGCAATAACAAGTTCTGTACATTGGGCATGTTGAACGCCCACAAGCGCGTGCACTCTCGAGGCAAGTTTGCGGCCAGCATCTGTGAAGTCTGTGGAAAGCACCTTCCGAACAAATCGAGCTATAACCGGCACAAACAGATTCATTCAGGCGAGAAGAACTTCAAATGTGGCTACTGTGGCAAGGCTTTTGTCCGCAAGCATGCTCTTAAAGTCCACATGTATTCACACCCTCTGAAAGAAGACTATTCCTGCCTGGAGTGCTCAATATCGTATGAAGACATTGAGGGCCTACAGAGACATGTCATGATTGCTCATAAAGATGAGGATGAGACTCTCATGTGTAACATCTGTAAAGAGCATGTGGAGGTTCCCCTGTTCATTGACCACTACAGGGCTTGCCACCTTCTCAAGGAGGATGAGATGCTCTCCAGACGGCTCAGCGCTGTGACTTGCCAAATCTGCTCCAAGGTGTTTTCCACACCGGCAACCTTAAATCGTCATTCTAAGCTCCACAATCCTCTGTTCAGTCGGGCCAGCACATGCGAGATCTGCCAGGAGATTATTGTCGGGCGGAGAAACATCATATCACATGCCAGGACTCACTATGACGAGTCCAATATGCCAGAGAAATACCAACGAATCAGCCGTTCGCTGGTACGGGATCAGAAGTACCGGAAGACTGCGGCGCAGAAGAGCTACATCTGTGAGTACTGTGGACGTGAGTTCAACAAGACCATAAACCTCCAAATTCACATCCGACGTCATACTGGTGAGAAACCATATATGTGCCAGATGTGCGGTATGGCGTTTTACACTCGTCAGCAACTGTCTATCCACATCCGAACACATACAGGTGAACGTCCTTACACTTGCAAGGCCGCTGGTTGCGGCAAGACATTCTCCAGCCCTGCGGCTATCTATATGCACAGGAAGATCCACAGCGATGCCCAGATGTACCGGTGCCACATCTGTGAGAAGACTTTTACCAAACGACTAACATATATTGGCCACGTTCGAGCACATACTAATGAGCGGCCATTTAGGTGCTCACAGTGCCCTGGTGCATTCACTCTGCGGAGCAAGCTGAATTTGCATATGAATAAACACAAGCAAGAGGCAGAGAGAGAGGCACTCACATGCTCAGACTGCAATACTACGTTTGCAACAGTGGAGGATCTAGATGTACATTGTGCAGACCAGTGTTACATCACCGTGCACACATATGAGGAGGGAGAGGAGCTGGATATTGACGGTCAAGCCCAAGTCATTGTTTTGAACCCAGAGGACTTTGCTGACATTGAGAGCAGTTTTATTGAAGAAGAGGATGGACTTTAA
Protein Sequence
MAENRPVQTTASTAAEEVCRLCGKTKVDLVSIYSEEASAKNILQKMKDLLNINVTPQDKLSKRVCHPCVTQLTLCDGMVEFFMKNQEVLKKKYPEDTQPGELSKDLSTDADSGEPSEACAVDGDEATLSPVEEPPNINTNASTDGPREKINVELCRVSSTVLCVCSAASFFVPARTVMRGHGSSRGSGLELVAVLLVLGLLRARWGYCDAITQSLGVSINQDMLFALHGLDATLPVACDFCESEFDDLEKFDIHMASHKEVRFFSCQLCTNTYMSWSNLVAHRKACHGGSVLSCEECSERRYHPDLGPVNYAVGDFPVGCEECGAGFHSLNELYRHFRDQANHNTVRRVKIAKFGVMGLVLTTFEIQGQNLGTVLAVKRTRLPSKGLQKIKSLPSKGLQETKRLPSNSRQENKRLPSKDLQKIKRLLSRSHRESKSLPFKGLQETKSLLSKSLQESKSLPSKGRKENKSLPSKVCDEPNSKSKEEKVGQPRLAKPVKKKPTFRAMSVRFMCPTCGIQFFTADKLTEHLARLPKEGFVCETCNNKFCTLGMLNAHKRVHSRGKFAASICEVCGKHLPNKSSYNRHKQIHSGEKNFKCGYCGKAFVRKHALKVHMYSHPLKEDYSCLECSISYEDIEGLQRHVMIAHKDEDETLMCNICKEHVEVPLFIDHYRACHLLKEDEMLSRRLSAVTCQICSKVFSTPATLNRHSKLHNPLFSRASTCEICQEIIVGRRNIISHARTHYDESNMPEKYQRISRSLVRDQKYRKTAAQKSYICEYCGREFNKTINLQIHIRRHTGEKPYMCQMCGMAFYTRQQLSIHIRTHTGERPYTCKAAGCGKTFSSPAAIYMHRKIHSDAQMYRCHICEKTFTKRLTYIGHVRAHTNERPFRCSQCPGAFTLRSKLNLHMNKHKQEAEREALTCSDCNTTFATVEDLDVHCADQCYITVHTYEEGEELDIDGQAQVIVLNPEDFADIESSFIEEEDGL*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-