Tshe003755.1
Basic Information
- Insect
- Timema shepardi
- Gene Symbol
- -
- Assembly
- GCA_902151425.1
- Location
- CABFVX010000162.1:291837-293192[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.00024 0.065 16.1 4.2 1 23 35 57 35 57 0.96 2 13 6.5e-05 0.018 17.9 0.7 1 23 92 114 92 114 0.98 3 13 0.0085 2.3 11.2 5.6 2 21 122 141 121 143 0.93 4 13 0.00042 0.11 15.3 2.1 1 23 146 168 146 168 0.98 5 13 1.3e-05 0.0035 20.1 2.5 1 23 174 196 174 196 0.98 6 13 0.00088 0.24 14.3 5.4 1 23 202 224 202 224 0.97 7 13 0.00016 0.042 16.7 1.0 1 23 230 252 230 252 0.97 8 13 8.9e-05 0.024 17.5 0.2 1 23 258 281 258 281 0.95 9 13 0.00059 0.16 14.9 3.3 1 21 291 311 291 313 0.94 10 13 4.2e-05 0.011 18.5 0.8 1 23 319 341 319 341 0.95 11 13 5.2e-07 0.00014 24.5 0.4 2 23 348 369 348 369 0.97 12 13 5.3e-07 0.00014 24.5 5.1 1 23 375 397 375 397 0.98 13 13 1.8e-06 0.0005 22.7 0.5 1 23 403 425 403 425 0.98
Sequence Information
- Coding Sequence
- ATGAAAACGAACCCTCAAGAGAACAAGCGCACATTTTTTGGTCAGGTCCCGTCCGAGGGCGGTATTTCGACCTGCCTTACCAGCGGCACGGGAATCCCGACTCACTTCTGCACGATGTGCGGCGTAGTGTTCAAATCTGACTCGAAACTTTGCTCCCACATCCAGACTCATTTGGAAGAGCGTTTGCCCGCGTGTGAGGCATATGGAAAAATATTCTCCTCCACAGACAATTTAAACTCTCGCATGGAAGACTGTTGTAAAGGTGAACAAGTATTTGTGTGCGAACTGTGCGAAAACACCTTCACGTCCGATAAGAATCTCAGTTCACACATGAAGATTCATCTTGCGGAGCGAGACCCTTGCACCTGCGACAGCTGCGGTAAAACCTTCGTTAACAGGAAGAAGTTGCTCGGGCATATGAAGTGTCACAAGAACCACAAATGTCCGACTTGCGGCAGAGACTTCAACTTGATCAAACGGCTCAGGATCCACATGAAGAGCCACAGCGAGGAGCGGCCGTACTCCTGCGACGTCTGCTACAAGAAGTTCAAGCGCTCGTACTACCTCATCGACCACCGCAAGATTCACACGGGGGAGAAACTACACGAGTGCGATGTGTGCGGTTACACGTGTATCCAGAAGGTGCACCTGGTGAACCACAAGAAGAGGCACTTCAATCAGTACAAGTTCGACTGCGACCTCTGCGGTAAGGGGTTCCACACCAACACCGAGCTTCAAGGTCACAAGAACGTCCACCTGGGGGAACGGCCGTACATGTGTGATATATGTGGTAAGGCGTACCCTTCCAAGACTAACATGATGGGGCATAAAAGGGCACAACACCCAGAAACTGCTCAGAACCCTAAAAAATACGAGTGCGACATCTGCCGTAAGACGTTCACTTACAAACGTTCCTTACTGCTCCACGCGCGTTGTCACACAGGCGAAAGCAACTTCCTCTGTGACGTGTGCGGGAAGGCGTTGTCGAGCTGCGAGACACTCAAGGCCCATCGCCGGATCCATACGGGAGAGAAGCCCAACGTGTGCAGTGTTTGCGGTAAGGCGTTTGGCAAGTCGAGTTACCTGAAGGTCCACCAGAGGACCCATACCGGGGAACGTCCCCACACCTGTGATCACTGCGGTAAATCTTTCACCCAGCGGTCCACGCTGGTGATACACCAGCGCTACCATACGGGTCAGAGGCCGTACCAGTGCGAGATTTGCTCCAAGGGGTTTGTCTCCAAGGCACTGTTAAAAACACACCAGATGAATCACGATGTCTCTAGTACGAATCTGGTCCTCATAGGACACCAAGACATTCATACTCATGCAAACATTGACCTTgacaagttttga
- Protein Sequence
- MKTNPQENKRTFFGQVPSEGGISTCLTSGTGIPTHFCTMCGVVFKSDSKLCSHIQTHLEERLPACEAYGKIFSSTDNLNSRMEDCCKGEQVFVCELCENTFTSDKNLSSHMKIHLAERDPCTCDSCGKTFVNRKKLLGHMKCHKNHKCPTCGRDFNLIKRLRIHMKSHSEERPYSCDVCYKKFKRSYYLIDHRKIHTGEKLHECDVCGYTCIQKVHLVNHKKRHFNQYKFDCDLCGKGFHTNTELQGHKNVHLGERPYMCDICGKAYPSKTNMMGHKRAQHPETAQNPKKYECDICRKTFTYKRSLLLHARCHTGESNFLCDVCGKALSSCETLKAHRRIHTGEKPNVCSVCGKAFGKSSYLKVHQRTHTGERPHTCDHCGKSFTQRSTLVIHQRYHTGQRPYQCEICSKGFVSKALLKTHQMNHDVSSTNLVLIGHQDIHTHANIDLDKF*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01445004;
- 90% Identity
- iTF_01446829;
- 80% Identity
- -