Basic Information

Insect: Timema shepardi
Gene Symbol: ZFX
Assembly: GCA_902151425.1
Location: CABFVX010005392.1:1-19413[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.088 24 8.0 4.5 2 23 256 277 255 277 0.96

2 18 6.8e-06 0.0019 21.0 1.5 2 23 283 304 283 304 0.97

3 18 0.00014 0.037 16.9 0.8 1 21 310 330 310 331 0.95

4 18 0.0011 0.3 14.0 0.4 1 23 358 380 358 380 0.98

5 18 0.00062 0.17 14.8 2.3 1 23 383 405 383 405 0.98

6 18 0.00023 0.064 16.1 0.5 2 23 414 435 413 435 0.96

7 18 0.0012 0.32 13.9 0.4 1 23 467 489 467 489 0.98

8 18 0.3 81 6.4 0.7 1 23 495 518 495 518 0.94

9 18 2.4e-05 0.0064 19.3 0.5 1 23 564 587 564 587 0.96

10 18 1.2e-05 0.0033 20.2 1.9 1 23 593 615 593 615 0.98

11 18 0.096 26 7.9 0.4 2 23 623 644 622 644 0.93

12 18 0.0058 1.6 11.7 0.1 1 23 650 672 650 672 0.98

13 18 0.00031 0.083 15.8 3.4 1 23 695 717 695 717 0.98

14 18 0.0018 0.5 13.3 4.0 1 23 723 746 723 746 0.96

15 18 1.5e-05 0.0042 19.9 0.5 1 23 772 794 772 794 0.97

16 18 0.011 3 10.8 0.5 1 23 830 852 830 852 0.91

17 18 0.041 11 9.1 0.4 1 21 887 907 887 908 0.93

18 18 0.00016 0.044 16.6 0.7 2 23 944 965 943 965 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.088	24	8.0	4.5	2	23	256	277	255	277	0.96
2	18	6.8e-06	0.0019	21.0	1.5	2	23	283	304	283	304	0.97
3	18	0.00014	0.037	16.9	0.8	1	21	310	330	310	331	0.95
4	18	0.0011	0.3	14.0	0.4	1	23	358	380	358	380	0.98
5	18	0.00062	0.17	14.8	2.3	1	23	383	405	383	405	0.98
6	18	0.00023	0.064	16.1	0.5	2	23	414	435	413	435	0.96
7	18	0.0012	0.32	13.9	0.4	1	23	467	489	467	489	0.98
8	18	0.3	81	6.4	0.7	1	23	495	518	495	518	0.94
9	18	2.4e-05	0.0064	19.3	0.5	1	23	564	587	564	587	0.96
10	18	1.2e-05	0.0033	20.2	1.9	1	23	593	615	593	615	0.98
11	18	0.096	26	7.9	0.4	2	23	623	644	622	644	0.93
12	18	0.0058	1.6	11.7	0.1	1	23	650	672	650	672	0.98
13	18	0.00031	0.083	15.8	3.4	1	23	695	717	695	717	0.98
14	18	0.0018	0.5	13.3	4.0	1	23	723	746	723	746	0.96
15	18	1.5e-05	0.0042	19.9	0.5	1	23	772	794	772	794	0.97
16	18	0.011	3	10.8	0.5	1	23	830	852	830	852	0.91
17	18	0.041	11	9.1	0.4	1	21	887	907	887	908	0.93
18	18	0.00016	0.044	16.6	0.7	2	23	944	965	943	965	0.92

Sequence Information

Coding Sequence: ATGCATGCCACTGATACACTTTGGTTGCAGGTTTCCAAAAGAGACGGACTGCCGACACAGATCTGTCGGCAATGCCTGCACAAGGTGAACTTGTGGCATGACTTCAAGCGGGTGTGCGACTCCTCGCAGGAGCGGCTCAAAGAATGGTTCAACCAGACCCACACTCGGAACAACCAGCCGCGGGAGTCGGTTGAGCATGACAGGGTGGTGATAAAACAAGAGACAATCGATGTCGAGGAAGATGATGACATGATTGAAATCACCCGCCATGATGAGATGAGAGAATCCTCGaTGATAGAAATCAAGCAAGAAGAAATTGAGGtttgtgatgatgatgatgatgataataatggtGACGCTGATGAATTTGTGAACGccattgaaattattaatgacCCGTTGAGCTTTCCCTCttcaaagaataataaaagtcCATTGCCGCTGTCGAAGACTATAAAAATAGAACCCGAAGATCCTGATGTTCAACATGTTTATGATCATCCTGTTCTTATTGGCGATTATTCTGGAATCGAAAATGGGGACACAATAGATTTAAATGGTGTGAATCATAGTGGAGCGTTGTCAATGCAAGGCATATTTGATCCCGAAAGACCAATCAAGCTGGAAATTAATGACCAAATACCTAATCGTCGTAAAAGGAGAAGAAAGTATTTCAAAAGGATCACGGTTAAGAAGAAACCtaaaatcaaacaaacactTTGGGCCAACCCCAAAGATATAGTATCTAAAACGCAGGATGGGTGCAAATGTAGAAAGTGTGGAGATTCCTTCCCCGATTTGTGTTCGCTCAAGACTCATGAAAAGGTTCACGCTGCTGCGGAAAATGTCTGCACAATATGTGACAAACGTTATTCCAGCAAAGGTTGTCTAGTCCGACACATACGTATCCACACGGGGCAGAAACCATATATTTGCTCCATCTGTAAGAAGTCATTCCCATACAAGTCTGCTTACACACAGCATCGTAATAATTGCAGTGAGTTAATTAATGCTACTGAAATCAAGAAAGAAATAGAACAAGATGAAGATAATTTGCCCAACGCAAATACCTATTCTTGTTATGTGTGTGAAAAGCCGTTTCCGAATGTGAATCAAATGATCTCTCACAGGAGAAGTCATAGTTCTTTCTCGTGTCATAAGTGTAAGAAGATGTTTGCTGGCGGAACTGGATTGAGCAACCATTTGCGAACACACACCAATGTGTTACACTCATACTTGTCGTGTTTTGTTTGTTGGAAATCTTTCAAGAGTAAACTAGCATTAGAGGTGCATAAAAGAGTGCACAAGAAAGTATTAACACCTCCATCGATTGCCAAGACTGTTATCAACAGTAAACTACTACAAAACAACGCTGACGggaaaaaaccaacaaatggGTTCGTTTGTGAAGTCTGTGACAAGTGGTTCAAAggttttaatatgttaacaagACACATGATCTCTCACACAAAATCAAAGGAGTTTGCGTGCACATTATGCAGCTCAACAATGGGCTATGCCTCTTCTCTGCACAAACACATGCAGGTTGTccacaatattaatattgattataaacaAATCAAGCCTAACAATCTATCATCTCCTGCCATGAAGGATAACAAACCCAAGTTCATTACTGCTGCATCTGCACAGATAAATGATCAGCAAGCATCAACTCAATCAGGGAACCACGTATGCACTATATGCACTAAAAGCTTCCCCGAGAAGAGTATGTTGGTGAGCCACATAAAAATCATACACATGGGAGTGAAGGCTTATAAATGTAGTGTTTGTTCGAAAATGTTTGCCTCGAGGATTCACTTGGTGAAGCACATGGATTCTCATTCTGAGAACTTAGATGAGCTCTCGTGCAAAATTTGCCTCAAACAGTTTCCCGACCTTAAACGATTGAACCTTCACAAAGGAGTCCACAAACGTTTCAAATTCTACAAGTGTGACATTTGCTTGGAGTCGTTCAACGGTTTGAAAGCTTGGAACAACCACCAAATGGCGCATGCCTTTAGAGATTCTCCACTGACACCTCTAAATGATGCTCCTCTAGAATCGTGCCCCACCGGAACATACACTTGCCGCTTGTGTTTCAAGATGTTCACTTCAAGATCTGACCTATACGAACATAAGAAAATGCACATCAAGCTGAAGATATTTTCATGCTCACATTGCAAAAACTCTTACAATAGTTCTTCTGCTTtgacaaaacataaaataagaaatcatCGTGGAGGTGGCCTTCCAATAAATCCATTCGCAGATCCACGCAAGGTCAATCGTGTCCTCAATCAGGAAAGGTTATTTGTGTGTGAAATTTGTTCTAAGCCATTTAACAATTCATCTGGGCTGAGCAAACACAGATTACAACACgcggatattttatttaagaatgtaaagCAAGTGAAAACAGTAAAACCCACTGCCCagaaaaacacatatttaaaaaaatcggttCCAGCCACCAAAGAGGGCACATTTGTTTGCGAACCTTGTAATCGCTCATTCAATGACTGGCAGTCGTTTACCACACACAAGGGCTGGCACACCAGGAAGCACGCCCCACTAGACCGTATGCTTCCTTTGAAAGATACACCGAGTCCTGTCAAGAACTCGCCTGCTGTTGACAACAATGTGGTGGTTCATAAACATAAGTGTAATGCTTGTGCCAAAATGTTCTCAACCCCTGGAAGATTGTCGCAGCACGAACAATCCTGTCCGATAGTCGCCATTAAAAGAAAGATGGCTATTGAAGATCAATTTAAGAAACCTTCTTTGAAAGAACAATCTGAAACTCcacaagataaaaataagaaagttGAATGTTCAGTATGCCACAAAATGTTTGCAAACAAAAAAGCCTTAATAAGACATAAAGGATGGCATTCTAGGTCTCCTAATTCTCGACTGAAGAGCTATAAATTAGAATTTAGCCAGTTCAGTAAAGATGAAAACGACACTCCTATACAAGAAACACCTCTTTTCATTGAAACGCCACTTGTCGAAACACCGTTGGTTGAAAAACAACTTCTCCCTGAAACACCACTCGCAGATGTAAAAACACTTTCGGGTGCTCACGATTCATCACCTATAGNN
Protein Sequence: MHATDTLWLQVSKRDGLPTQICRQCLHKVNLWHDFKRVCDSSQERLKEWFNQTHTRNNQPRESVEHDRVVIKQETIDVEEDDDMIEITRHDEMRESSMIEIKQEEIEVCDDDDDDNNGDADEFVNAIEIINDPLSFPSSKNNKSPLPLSKTIKIEPEDPDVQHVYDHPVLIGDYSGIENGDTIDLNGVNHSGALSMQGIFDPERPIKLEINDQIPNRRKRRRKYFKRITVKKKPKIKQTLWANPKDIVSKTQDGCKCRKCGDSFPDLCSLKTHEKVHAAAENVCTICDKRYSSKGCLVRHIRIHTGQKPYICSICKKSFPYKSAYTQHRNNCSELINATEIKKEIEQDEDNLPNANTYSCYVCEKPFPNVNQMISHRRSHSSFSCHKCKKMFAGGTGLSNHLRTHTNVLHSYLSCFVCWKSFKSKLALEVHKRVHKKVLTPPSIAKTVINSKLLQNNADGKKPTNGFVCEVCDKWFKGFNMLTRHMISHTKSKEFACTLCSSTMGYASSLHKHMQVVHNINIDYKQIKPNNLSSPAMKDNKPKFITAASAQINDQQASTQSGNHVCTICTKSFPEKSMLVSHIKIIHMGVKAYKCSVCSKMFASRIHLVKHMDSHSENLDELSCKICLKQFPDLKRLNLHKGVHKRFKFYKCDICLESFNGLKAWNNHQMAHAFRDSPLTPLNDAPLESCPTGTYTCRLCFKMFTSRSDLYEHKKMHIKLKIFSCSHCKNSYNSSSALTKHKIRNHRGGGLPINPFADPRKVNRVLNQERLFVCEICSKPFNNSSGLSKHRLQHADILFKNVKQVKTVKPTAQKNTYLKKSVPATKEGTFVCEPCNRSFNDWQSFTTHKGWHTRKHAPLDRMLPLKDTPSPVKNSPAVDNNVVVHKHKCNACAKMFSTPGRLSQHEQSCPIVAIKRKMAIEDQFKKPSLKEQSETPQDKNKKVECSVCHKMFANKKALIRHKGWHSRSPNSRLKSYKLEFSQFSKDENDTPIQETPLFIETPLVETPLVEKQLLPETPLADVKTLSGAHDSSPIX

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -